DT-Web

DB02337 - S-(D-Carboxybutyl)-L-Homocysteine


Identification
Name S-(D-Carboxybutyl)-L-Homocysteine
Accession Number DB02337 (EXPT00843)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 235.301
Groups experimental
Monoisotopic Weight 235.087828727
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Betaine--homocysteine S-methyltransferase 1
Name Betaine--homocysteine S-methyltransferase 1
Gene Name BHMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6518

Predictions


Id Partner name Gene Name Score
3996 Betaine--homocysteine S-methyltransferase 2 BHMT2 0.0401
480 Methionine-R-sulfoxide reductase B2 MSRB2 0.037
317 Methionine-R-sulfoxide reductase SEPX1 0.037
3995 Methionyl-tRNA synthetase, mitochondrial MARS2 0.0369
3921 Methionine adenosyltransferase 2 subunit beta MAT2B 0.0369
600 Methionyl-tRNA synthetase, cytoplasmic MARS 0.0369
191 Peptide methionine sulfoxide reductase MSRA 0.033
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.029
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0279
840 Methionine synthase reductase, mitochondrial MTRR 0.0239
809 Methionine synthase MTR 0.0223
2935 Methionine synthase metH 0.0223
2795 Methionine aminopeptidase 2 METAP2 0.0223
3426 Glutamine synthetase glnA 0.0209
3987 Glutamine synthetase GLUL 0.0209
3917 Methylenetetrahydrofolate reductase MTHFR 0.0183
6151 Monocarboxylate transporter 10 SLC16A10 0.017
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0099
5590 N utilization substance protein B homolog nusB 0.0099
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0099
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0099
2300 Lysozyme E 0.0099
3633 Lysozyme R 0.0099
5597 Lysozyme 17 0.0099
5588 Cell division protein FtsY TM_0570 0.0099
5591 Complement component C8 gamma chain C8G 0.0099
2838 Ribose-5-phosphate isomerase A rpiA 0.0099
2952 Ribose-5-phosphate isomerase A rpiA 0.0099
5595 Ribose-5-phosphate isomerase A rpiA 0.0099
4695 UPF0124 protein yfiH yfiH 0.0099
4238 50S ribosomal protein L4 rplD 0.0099
5578 50S ribosomal protein L4 rplD 0.0099
6173 50S ribosomal protein L4 rplD 0.0099
6219 50S ribosomal protein L4 rplD 0.0099
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0099
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0099
5587 Iron(III)-binding periplasmic protein fbpA 0.0099
5600 Pyruvate decarboxylase pdc 0.0099
5582 Regulator of transcription; stringent starvation protein A sspA 0.0099
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0099
5593 Transferase Not Available 0.0099
5581 Beta-fructosidase bfrA 0.0099
5060 Intron-associated endonuclease 1 ITEVIR 0.0099
4375 Glutamine synthetase 1 glnA1 0.0099
5575 Short tail fiber protein 12 0.0099
5574 Invasin YPTB1668 0.0099
5580 Hexon protein PII 0.0099
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0091
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0091
4992 Cytochrome c peroxidase Not Available 0.0091
5006 RNASE4 protein RNASE4 0.0088
2555 Pol polyprotein pol 0.0087
3242 Pol polyprotein gag-pol 0.0087
3471 Pol polyprotein gag-pro-pol 0.0087
5256 Pol polyprotein pol 0.0087
6469 Pol polyprotein gag-pol 0.0087
6565 Pol polyprotein Not Available 0.0087
4533 Glyoxalase family protein BC_1747 0.0086
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0085
3132 Tryptophan synthase alpha chain trpA 0.0085
6568 Tryptophan synthase alpha chain trpA 0.0085
3729 Citrate synthase gltA 0.0085
4575 Citrate synthase cit 0.0085
4580 Citrate synthase gltA 0.0085
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0085
5328 Prostaglandin F synthase Tb11.02.2310 0.0085
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0085
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0085
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0082
2149 Angiogenin ANG 0.008
2603 Beta-lactamase II blm 0.008
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0079
3583 6-phosphogluconolactonase pgl 0.0079
2521 Cell division protein ftsZ ftsZ 0.0078
3301 Cell division protein ftsZ ftsZ 0.0078
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0076
2286 Isocitrate dehydrogenase [NADP] icd 0.0075
2302 Isocitrate dehydrogenase [NADP] icd 0.0075
2771 Isocitrate dehydrogenase [NADP] icd 0.0075
3486 Fumarate hydratase class II fumC 0.0075
2942 Sialidase nanH 0.0074
3546 Sialidase nedA 0.0074
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0074
857 Malate dehydrogenase, mitochondrial MDH2 0.0071
332 Beta-lactamase blaZ 0.0071
2478 Beta-lactamase ampC 0.0071
2613 Beta-lactamase ampC 0.0071
2635 Beta-lactamase ampC 0.0071
2700 Beta-lactamase penP 0.0071
5445 Beta-lactamase blaB 0.0071
6019 Beta-lactamase SHV-7 0.0071
6701 Beta-lactamase cphA 0.0071
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.007
1123 Eosinophil cationic protein RNASE3 0.007
2452 Tryptophanyl-tRNA synthetase trpS 0.007
2697 Uridine-cytidine kinase 2 UCK2 0.0069
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0067
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0067
411 Glycine N-methyltransferase GNMT 0.0067
5579 Carboxypeptidase B CPB1 0.0064
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0062
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0062
3384 Macrophage migration inhibitory factor MIF 0.0062
128 Adenine phosphoribosyltransferase APRT 0.0057
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0049
5682 Ribonuclease pancreatic RNASE1 0.0049
822 Aldose reductase AKR1B1 0.0048
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0045
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0039
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