DT-Web

DB02105 - 3,5-Dinitrocatechol


Identification
Name 3,5-Dinitrocatechol
Accession Number DB02105 (EXPT01233)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 200.1058
Groups experimental
Monoisotopic Weight 200.00693587
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Catechol O-methyltransferase
Name Catechol O-methyltransferase
Gene Name COMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7737

Predictions


Id Partner name Gene Name Score
5455 Arylsulfatase A ARSA 0.0518
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0326
4757 Cytochrome P450 2C9 CYP2C9 0.0251
3939 Amine oxidase [flavin-containing] B MAOB 0.025
3941 Amine oxidase [flavin-containing] A MAOA 0.0243
146 Androgen receptor AR 0.021
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0204
193 Beta-1 adrenergic receptor ADRB1 0.0201
766 Beta-2 adrenergic receptor ADRB2 0.0195
318 Alpha-2A adrenergic receptor ADRA2A 0.0184
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0181
330 Spermidine synthase SRM 0.0149
3038 Spermidine synthase speE 0.0149
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0128
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0126
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0126
411 Glycine N-methyltransferase GNMT 0.0122
358 Cystathionine beta-synthase CBS 0.0117
6013 Cytochrome P450 2E1 CYP2E1 0.0094
3809 Estrogen-related receptor gamma ESRRG 0.0072
136 Estrogen receptor ESR1 0.0069
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0061
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.006
869 Estrogen receptor beta ESR2 0.0054
373 Transthyretin TTR 0.0051
153 Dopamine beta-hydroxylase DBH 0.0047
1588 Multidrug resistance protein 1 ABCB1 0.0046
3811 Cytochrome P450 19A1 CYP19A1 0.0045
4512 Cytochrome P450 3A4 CYP3A4 0.0041
5718 Cytochrome P450 2A6 CYP2A6 0.004
6149 Solute carrier family 22 member 10 SLC22A10 0.004
4200 Cytochrome P450 1A2 CYP1A2 0.0038
6167 Organic solute transporter subunit beta OSTB 0.0037
6166 Organic solute transporter subunit alpha OSTA 0.0037
163 D(1B) dopamine receptor DRD5 0.0036
432 D(4) dopamine receptor DRD4 0.0034
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0034
638 D(3) dopamine receptor DRD3 0.0033
4924 Cytochrome P450 2C8 CYP2C8 0.0033
713 Sodium-dependent dopamine transporter SLC6A3 0.0033
6147 Solute carrier family 22 member 3 SLC22A3 0.0032
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0031
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0031
23 D(1A) dopamine receptor DRD1 0.003
6141 Sodium/bile acid cotransporter SLC10A1 0.0029
118 Organic cation/carnitine transporter 2 SLC22A5 0.0029
6144 Solute carrier family 22 member 2 SLC22A2 0.0028
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0028
831 D(2) dopamine receptor DRD2 0.0028
6145 Solute carrier family 22 member 1 SLC22A1 0.0027
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0025
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0025
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0025
1024 Solute carrier family 22 member 11 SLC22A11 0.0024
2164 Multidrug resistance-associated protein 4 ABCC4 0.0023
6016 Cytochrome P450 2C19 CYP2C19 0.0022
862 Multidrug resistance-associated protein 1 ABCC1 0.0022
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0022
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0022
4119 Cytochrome P450 2D6 CYP2D6 0.0021
6142 Solute carrier family 22 member 8 SLC22A8 0.0021
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.002
1729 Solute carrier family 22 member 6 SLC22A6 0.0019
↑