DT-Web

DB03633 - Lpc-Ether


Identification
Name Lpc-Ether
Accession Number DB03633 (EXPT02056)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 510.7076
Groups experimental
Monoisotopic Weight 510.392350073
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Ganglioside GM2 activator
Name Ganglioside GM2 activator
Gene Name GM2A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0994
Phospholipase A2
Name Phospholipase A2
Gene Name PLA2G1B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2827

Predictions


Id Partner name Gene Name Score
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.1129
1588 Multidrug resistance protein 1 ABCB1 0.063
2981 Phospholipase A2, membrane associated PLA2G2A 0.0437
4615 Chain A, Red Copper Protein Nitrosocyanin NE0143 0.0389
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0339
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0339
4132 Chloride channel protein ClC-Ka CLCNKA 0.0292
1758 GTPase HRas HRAS 0.0282
2300 Lysozyme E 0.0194
3633 Lysozyme R 0.0194
5597 Lysozyme 17 0.0194
489 Monocarboxylate transporter 2 SLC16A7 0.0166
723 Cytosolic phospholipase A2 PLA2G4A 0.0141
738 Monocarboxylate transporter 1 SLC16A1 0.0126
871 Glucocorticoid receptor NR3C1 0.0123
394 Calcineurin subunit B isoform 1 PPP3R1 0.0122
6753 Apolipoprotein M APOM 0.0122
6742 Recoverin RCVRN 0.0122
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0122
6747 Chalcone/stilbene synthase family protein MT1417 0.0122
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0122
6743 Non-fluorescent flavoprotein luxF 0.0122
2528 Fatty acid metabolism regulator protein fadR 0.0122
6740 Fatty acid metabolism regulator protein fadR 0.0122
6751 Gag polyprotein gag 0.0122
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0122
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0122
6749 Polyprotein Not Available 0.0122
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.011
5961 Insulin INS 0.0107
6527 Lymphocyte antigen 96 LY96 0.0106
6755 Poliovirus receptor PVR 0.0106
6524 Protein tonB tonB 0.0098
6750 ADP-ribosylation factor 6 ARF6 0.0098
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0098
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0098
20 Prostaglandin G/H synthase 1 PTGS1 0.0096
290 Prostaglandin G/H synthase 2 PTGS2 0.0089
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0089
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0089
4210 Toll-like receptor 4 TLR4 0.0085
6316 ADP-ribosylation factor 1 ARF1 0.0083
2297 Genome polyprotein Not Available 0.0083
2322 Genome polyprotein Not Available 0.0083
2694 Genome polyprotein Not Available 0.0083
2719 Genome polyprotein Not Available 0.0083
2860 Genome polyprotein Not Available 0.0083
2928 Genome polyprotein Not Available 0.0083
3160 Genome polyprotein Not Available 0.0083
3260 Genome polyprotein Not Available 0.0083
4783 Genome polyprotein Not Available 0.0083
5726 Genome polyprotein Not Available 0.0083
5779 Genome polyprotein Not Available 0.0083
5867 Genome polyprotein Not Available 0.0083
6253 Genome polyprotein Not Available 0.0083
6301 Genome polyprotein Not Available 0.0083
6380 Genome polyprotein Not Available 0.0083
6381 Genome polyprotein Not Available 0.0083
6437 Genome polyprotein Not Available 0.0083
6520 Genome polyprotein Not Available 0.0083
6521 Genome polyprotein Not Available 0.0083
6652 Genome polyprotein Not Available 0.0083
6734 Genome polyprotein Not Available 0.0083
6735 Genome polyprotein Not Available 0.0083
6736 Genome polyprotein Not Available 0.0083
6737 Genome polyprotein Not Available 0.0083
6738 Genome polyprotein Not Available 0.0083
6739 Genome polyprotein Not Available 0.0083
6744 Genome polyprotein Not Available 0.0083
6748 Genome polyprotein Not Available 0.0083
6894 Genome polyprotein Not Available 0.0083
6898 Genome polyprotein Not Available 0.0083
864 Gag-Pol polyprotein gag-pol 0.0079
2237 Gag-Pol polyprotein gag-pol 0.0079
2326 Gag-Pol polyprotein gag-pol 0.0079
2451 Gag-Pol polyprotein gag-pol 0.0079
2901 Gag-Pol polyprotein gag-pol 0.0079
3165 Gag-Pol polyprotein gag-pol 0.0079
3722 Gag-Pol polyprotein gag-pol 0.0079
6306 Gag-Pol polyprotein gag-pol 0.0079
6624 Gag-Pol polyprotein gag-pol 0.0079
2391 Ferrochelatase hemH 0.0069
6502 Ferrochelatase DKFZp686P18130 0.0069
1591 Ferrochelatase, mitochondrial FECH 0.0069
6085 Fatty acid-binding protein, intestinal FABP2 0.0069
2427 Ferrichrome-iron receptor fhuA 0.0069
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0066
768 FK506-binding protein 1A FKBP1A 0.0066
6228 Nuclear receptor coactivator 1 NCOA1 0.0065
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0062
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.006
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.006
6493 Cytochrome c oxidase subunit 6C COX6C 0.006
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.006
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.006
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.006
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.006
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.006
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.006
6559 Cytochrome c oxidase subunit 2 ctaC 0.006
6669 Cytochrome c oxidase subunit 2 ctaC 0.006
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.006
371 Cytochrome c oxidase subunit 1 MT-CO1 0.006
6558 Cytochrome c oxidase subunit 1 ctaD 0.006
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.006
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0057
3587 Gastrotropin FABP6 0.0055
2540 Choloylglycine hydrolase cbh 0.0055
6501 Fatty acid-binding protein, liver FABP1 0.0052
465 Calmodulin CALM1 0.0049
4604 Liver carboxylesterase 1 CES1 0.0045
3809 Estrogen-related receptor gamma ESRRG 0.0042
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0037
517 Alcohol dehydrogenase 1C ADH1C 0.0036
4878 Glycoprotein hormones alpha chain CGA 0.0035
4877 Beta-mannanase man 0.0035
4850 Beta-2-glycoprotein 1 APOH 0.0035
4880 Membrane cofactor protein CD46 0.0035
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0035
1072 Granzyme B GZMB 0.0035
4889 Ig epsilon chain C region IGHE 0.0035
4189 Alpha-galactosidase A GLA 0.0035
4869 Major capsid protein A430L 0.0035
4852 Reticulon-4 receptor RTN4R 0.0035
757 Fusion glycoprotein F0 F 0.0035
4875 Fusion glycoprotein F0 F 0.0035
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0035
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0035
442 Envelope glycoprotein gp41 0.0035
4859 Envelope glycoprotein env 0.0035
4856 CD209 antigen CD209 0.0035
4721 Beta-1,4-mannanase manA 0.0035
4845 ADAM 33 ADAM33 0.0035
1354 Beta-glucuronidase GUSB 0.0035
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0035
3352 Structural polyprotein Not Available 0.0035
3628 Structural polyprotein Not Available 0.0035
4892 Structural polyprotein Not Available 0.0035
587 Serum albumin ALB 0.0032
6858 Inactive carboxylesterase 4 CES1P1 0.0031
1184 Interferon beta IFNB1 0.0031
793 T-cell surface antigen CD2 CD2 0.0031
4861 Interleukin-6 receptor alpha chain IL6R 0.0031
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0031
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0031
1379 Interleukin-12 subunit beta IL12B 0.0031
3837 Cytokine receptor common beta chain CSF2RB 0.0031
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0031
4890 Hemagglutinin HA 0.0031
6566 Hemagglutinin Not Available 0.0031
6141 Sodium/bile acid cotransporter SLC10A1 0.003
3444 Cyanovirin-N Not Available 0.0028
1859 Prostatic acid phosphatase ACPP 0.0028
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0028
3140 Hemagglutinin-neuraminidase HN 0.0028
3609 Hemagglutinin-neuraminidase HN 0.0028
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0028
4666 Fucose-binding lectin PA-IIL lecB 0.0027
2372 Bifunctional tail protein 9 0.0027
4787 Envelope glycoprotein gp160 env 0.0027
4820 Envelope glycoprotein gp160 env 0.0027
5727 Envelope glycoprotein gp160 env 0.0027
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0026
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0026
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0025
554 Low-density lipoprotein receptor LDLR 0.0025
852 Heparin cofactor 2 SERPIND1 0.0025
64 Neuraminidase NA 0.0025
641 Neuraminidase NA 0.0025
2676 Neuraminidase NA 0.0025
3026 Neuraminidase NA 0.0025
3519 Neuraminidase NA 0.0025
6007 Neuraminidase NA 0.0025
3480 Mannan endo-1,4-beta-mannosidase manA 0.0025
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0024
1439 Lactotransferrin LTF 0.0024
776 Bile salt export pump ABCB11 0.0024
1243 Cathepsin D CTSD 0.0023
595 Fibrinogen alpha chain FGA 0.0023
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0023
2430 Chondroitinase B cslB 0.0023
958 Insulin-like growth factor 1 receptor IGF1R 0.0023
2164 Multidrug resistance-associated protein 4 ABCC4 0.0023
6143 Solute carrier family 22 member 7 SLC22A7 0.0022
6307 Ig gamma-2 chain C region IGHG2 0.0022
2581 Chondroitinase AC cslA 0.0022
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0022
862 Multidrug resistance-associated protein 1 ABCC1 0.0022
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0022
6847 Lactase-phlorizin hydrolase LCT 0.0021
6142 Solute carrier family 22 member 8 SLC22A8 0.002
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.002
2207 Rhodopsin RHO 0.002
3814 Complement C1r subcomponent C1R 0.002
309 Antithrombin-III SERPINC1 0.0019
4785 Ig gamma-1 chain C region IGHG1 0.0018
76 Nitric-oxide synthase, brain NOS1 0.0018
952 Dipeptidyl peptidase 4 DPP4 0.0016
3923 Cholinesterase BCHE 0.0011
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