DT-Web

Holliday junction ATP-dependent DNA helicase ruvB


Partner ID 4755
Name Holliday junction ATP-dependent DNA helicase ruvB
Synonyms 1741
Gene name ruvB
General function Involved in nucleotide binding
Specific function The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvB is a Mg(2+)-dependent, DNA-dependent ATPase with an equal preference for supercoiled and linear duplex DNA. It can promote Holliday junction migration alone
Gene sequence + ...

GTGGAAGACCTCGCCCTTAGGCCCAAGACCCTGGACGAGTACATCGGCCAGGAGCGCCTGAAGCAAAAGCTCCGGGTCTACCTCGAGGCGGCCAAGGCCCGAAAAGAGCCCTTGGAGCACCTCCTCCTCTTCGGCCCCCCGGGCCTGGGCAAGACCACCCTGGCCCACGTCATCGCCCACGAGCTTGGGGTCAACCTCCGGGTCACCTCCGGGCCCGCCATAGAGAAGCCCGGGGACCTCGCCGCCATCCTGGCCAACTCCCTGGAGGAAGGGGACATCCTCTTCATTGACGAGATCCACCGCCTGAGCCGCCAGGCCGAGGAGCACCTCTACCCCGCCATGGAGGACTTCGTCATGGACATCGTCATCGGCCAAGGTCCGGCGGCGAGGACCATCCGGCTGGAGCTTCCCCGCTTCACCCTGATCGGGGCCACCACCCGGCCCGGCCTCATCACCGCGCCCCTCCTGAGCCGCTTCGGCATCGTGGAGCACCTGGAGTACTACACCCCTGAGGAGCTGGCCCAAGGGGTGATGCGGGACGCCCGCCTCCTCGGGGTGAGGATCACGGAGGAGGCCGCCCTGGAGATCGGTAGGCGGAGCCGGGGCACCATGCGCGTCGCCAAGCGCCTCTTCCGGAGGGTGCGGGACTTCGCCCAGGTGGCGGGGGAGGAGGTCATCACCCGGGAGCGGGCCCTGGAGGCCCTTGCCGCCCTGGGCCTGGACGAGCTGGGCTTGGAGAAGCGGGACCGGGAGATCCTGGAGGTCCTCATCCTCCGCTTCGGCGGCGGCCCCGTGGGCCTCGCCACCCTGGCCACCGCCCTCTCCGAGGACCCGGGCACCTTGGAAGAGGTGCACGAGCCCTACCTCATCCGCCAGGGCCTTTTGAAGCGCACTCCCCGGGGCCGGGTGGCCACGGAACTGGCCTACCGCCACCTGGGCTACCCGCCCCCGGTGGGCCCCCTCTTGGAGCCGTGA
Protein sequence + ...

MEDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAILANSLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAPLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTMRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREILEVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVATELAYRHLGYPPPVGPLLEP
GO Classification
function
adenyl nucleotide binding
ATP binding
nucleic acid binding
helicase activity
DNA helicase activity
hydrolase activity, acting on acid anhydrides
Holliday junction helicase activity
binding
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
nucleotide binding
nucleoside-triphosphatase activity
catalytic activity
DNA binding
hydrolase activity
purine nucleotide binding
process
response to biotic stimulus
defense response
DNA recombination
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
defense response to pathogen
physiological process
metabolism
DNA metabolism
cellular metabolism
response to stimulus
DNA repair
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Drugs


Associated as Target

Id Name
DB00173 Adenine

Associated as Prediction

Id Name
DB00118 S-Adenosylmethionine
DB00121 Biotin
DB00128 L-Aspartic Acid
DB00131 Adenosine monophosphate
DB00134 L-Methionine
DB00140 Riboflavin
DB00142 L-Glutamic Acid
DB00143 Glutathione
DB00145 Glycine
DB00147 Pyridoxal
DB00148 Creatine
DB00151 L-Cysteine
DB00157 NADH
DB00165 Pyridoxine
DB00171 Adenosine triphosphate
DB00173 Adenine
DB00175 Pravastatin
DB00180 Flunisolide
DB00197 Troglitazone
DB00223 Diflorasone
DB00227 Lovastatin
DB00240 Alclometasone
DB00242 Cladribine
DB00253 Medrysone
DB00288 Amcinonide
DB00295 Morphine
DB00300 Tenofovir
DB00316 Acetaminophen
DB00324 Fluorometholone
DB00328 Indomethacin
DB00351 Megestrol
DB00373 Timolol
DB00394 Beclometasone dipropionate
DB00398 Sorafenib
DB00439 Cerivastatin
DB00441 Gemcitabine
DB00443 Betamethasone
DB00530 Erlotinib
DB00536 Guanidine
DB00547 Desoximetasone
DB00586 Diclofenac
DB00588 Fluticasone Propionate
DB00591 Fluocinolone Acetonide
DB00596 Halobetasol Propionate
DB00615 Rifabutin
DB00619 Imatinib
DB00620 Triamcinolone
DB00631 Clofarabine
DB00635 Prednisone
DB00641 Simvastatin
DB00642 Pemetrexed
DB00663 Flumethasone Pivalate
DB00678 Losartan
DB00687 Fludrocortisone
DB00688 Mycophenolate mofetil
DB00704 Naltrexone
DB00709 Lamivudine
DB00712 Flurbiprofen
DB00716 Nedocromil
DB00718 Adefovir Dipivoxil
DB00741 Hydrocortisone
DB00756 Hexachlorophene
DB00762 Irinotecan
DB00764 Mometasone
DB00769 Hydrocortamate
DB00773 Etoposide
DB00783 Estradiol
DB00787 Acyclovir
DB00788 Naproxen
DB00818 Propofol
DB00834 Mifepristone
DB00838 Clocortolone
DB00846 Flurandrenolide
DB00860 Prednisolone
DB00870 Suprofen
DB00873 Loteprednol
DB00879 Emtricitabine
DB00887 Bumetanide
DB00896 Rimexolone
DB00943 Zalcitabine
DB00959 Methylprednisolone
DB00973 Ezetimibe
DB00987 Cytarabine
DB01004 Ganciclovir
DB01013 Clobetasol
DB01015 Sulfamethoxazole
DB01016 Glyburide
DB01024 Mycophenolic acid
DB01045 Rifampin
DB01047 Fluocinonide
DB01048 Abacavir
DB01050 Ibuprofen
DB01073 Fludarabine
DB01076 Atorvastatin
DB01095 Fluvastatin
DB01098 Rosuvastatin
DB01130 Prednicarbate
DB01185 Fluoxymesterone
DB01222 Budesonide
DB01234 Dexamethasone
DB01254 Dasatinib
DB01259 Lapatinib
DB01260 Desonide
DB01262 Decitabine
DB01268 Sunitinib
DB01280 Nelarabine
DB01356 Lithium
DB01380 Cortisone acetate
DB01384 Paramethasone
DB01410 Ciclesonide
DB01420 Testosterone Propionate
DB01544 Flunitrazepam
DB01632 Alpha-Phosphoribosylpyrophosphoric Acid
DB01643 Thymidine-5'-Phosphate
DB01660 Adenosine-5'-Diphosphate Monothiophosphate
DB01673 Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine
DB01688 P-Cresol
DB01690 Bis(Adenosine)-5'-Triphosphate
DB01715 7,8-Diamino-Nonanoic Acid
DB01717 Bis(Adenosine)-5'-Pentaphosphate
DB01722 Ethylbenzene
DB01726 2-Aminophenol
DB01772 3-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-Dione
DB01783 Pantothenic acid
DB01793 I-5
DB01812 Adenosine-3'-5'-Diphosphate
DB01842 3'-Phosphate-Adenosine-5'-Diphosphate
DB01845 N-Butylbenzene
DB01863 Inositol 1,3,4,5-Tetrakisphosphate
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01932 5-Methylpyrrole
DB01936 Ribose
DB01942 Formic Acid
DB01944 (S)-blebbistatin
DB01950 N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)Urea
DB01957 3-Chlorophenol
DB01961 Cytidine-3'-Monophosphate
DB01962 Phosphonotyrosine
DB01972 Guanosine-5'-Monophosphate
DB01986 3-Fluoro-2-Methyl-Aniline
DB01992 Coenzyme A
DB02007 Alpha-D-Glucose-6-Phosphate
DB02010 Staurosporine
DB02030 Alpha-Ribazole-5'-Phosphate
DB02052 Indirubin-3'-Monoxime
DB02097 Cytidine
DB02098 Adenosine-2'-5'-Diphosphate
DB02103 2-Chlorodideoxyadenosine
DB02119 6-Hydroxymethyl-7,8-Dihydropterin
DB02147 Cyclo-Tetrametavanadate
DB02158 (1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol
DB02163 2,5-Xylidine
DB02168 Bromopurine
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02210 Hexane-1,6-Diol
DB02212 Pyrophosphate 2-
DB02236 Glycinamide Ribonucleotide
DB02281 Formycin
DB02282 5'-Deoxy-5'-Methylthioadenosine
DB02314 Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate
DB02324 5-Iodo-2'-Deoxyuridine-5'-Monophosphate
DB02345 Selenocysteine
DB02359 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
DB02363 2'-Monophosphoadenosine-5'-Diphosphate
DB02379 Beta-D-Glucose
DB02382 Namn
DB02403 2-Fluoroaniline
DB02424 Geldanamycin
DB02431 Cytidine-5'-Triphosphate
DB02437 (5r)-5-Amino-6-Hydroxyhexylcarbamic Acid
DB02448 N-Tridecanoic Acid
DB02453 Trihydroxyantimonite(Iii)
DB02482 Phosphonothreonine
DB02486 2-Hydroxyethyl Disulfide
DB02490 (Diaminomethyl-Methyl-Amino)-Acetic Acid
DB02495 9-(4-Hydroxybutyl)-N2-Phenylguanine
DB02500 6-(Dihydroxy-Isobutyl)-Thymine
DB02524 Spiro(2,4,6-Trinitrobenzene[1,2a]-2o',3o'-Methylene-Adenine-Triphosphate
DB02534 2-Allylphenol
DB02550 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02573 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate
DB02591 5,6-Dimethylbenzimidazole
DB02594 2'-Deoxycytidine
DB02596 Alpha,Beta-Methyleneadenosine-5'-Triphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02621 Latrunculin A
DB02659 Cholic Acid
DB02661 Adenosine-5'-Diphosphate-2',3'-Vanadate
DB02663 2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid
DB02714 3'-Uridinemonophosphate
DB02733 Purvalanol
DB02753 Selenoinosine
DB02754 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
DB02765 9-Hydroxypropyladenine, R-Isomer
DB02770 7-Alpha-D-Ribofuranosyl-2-Aminopurine-5'-Phosphate
DB02772 Sucrose
DB02795 P-Anisic Acid
DB02800 5-Hydroxymethylene-6-Hydrofolic Acid
DB02805 1-(3-O-Phosphono-Beta-L-Arabinofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB02815 Indene
DB02819 Mono-[3,4-Dihydroxy-5-(5-Methyl-Benzoimidazol-1-Yl)-Tetrahydor-Furan-2-Ylmethyl] Ester
DB02840 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid
DB02859 Soraphen A
DB02870 N-Allyl-Aniline
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB02905 Phosphoric Acid Mono-[3,4-Dihydroxy-5-(5-Hydroxy-Benzoimidazol-1-Yl)Tetrahydro-Furan-2-Ylmethyl] Ester
DB02921 (South)-Methanocarba-Thymidine
DB02927 Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid
DB02930 Phosphothiophosphoric Acid-Adenylate Ester
DB02933 5'-Deoxy-5'-(Methylthio)-Tubercidin
DB02935 1-Methoxy-2-(2-Methoxyethoxy)Ethane
DB02937 Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
DB02938 Heptanoic Acid
DB02941 3-(1-Aminoethyl)Nonanedioic Acid
DB02944 Alpha-D-Mannose
DB02962 Benzimidazole
DB02970 2-Propyl-Aniline
DB02987 Cysteine-S-Acetamide
DB03000 9-Hydroxypropyladenine, S-Isomer
DB03018 3,4-Dimethylaniline
DB03021 Ulapualide A
DB03029 Ortho-Xylene
DB03075 (Diphosphono)Aminophosphonic Acid
DB03079 Alpha-Ribazole-5'-Phosphate Derivative
DB03080 17-Dmag
DB03093 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
DB03103 Thymidine-5'- Diphosphate
DB03126 Mant-Adp
DB03137 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine
DB03150 2',3'-Dideoxythymidine-5'-Monophosphate
DB03155 1-(2-Deoxy-2-Fluoro-3-O-Phosphono-Beta-L-Ribofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB03169 (S)-Hmg-Coa
DB03177 5-methylbenzimidazole
DB03180 4,5-Dimethyl-1,2-Phenylenediamine
DB03186 U-Pi-a-Pi
DB03191 3-Oxiran-2ylalanine
DB03195 Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester
DB03197 6-Hydroxymethylpterin
DB03200 7-Alpha-D-Ribofuranosyl-Purine-5'-Phosphate
DB03222 2'-Deoxyadenosine 5'-Triphosphate
DB03226 Trifluoroethanol
DB03233 Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester
DB03238 3,5-Difluoroaniline
DB03247 Riboflavin Monophosphate
DB03255 Phenol
DB03280 P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate
DB03301 2-Allyl-6-Methyl-Phenol
DB03312 5-Bromovinyldeoxyuridine
DB03326 deoxycytidylyl-3',5'-guanosine
DB03345 Beta-Mercaptoethanol
DB03371 Modified Ribosylated Glutamyl Ester
DB03401 D-Myo-Inositol-1,4,5-Triphosphate
DB03403 Cytidine-5'-Monophosphate
DB03408 Gamma-Glutamylcysteine
DB03431 Adenosine-5'-Diphosphate
DB03434 3[N-Morpholino]Propane Sulfonic Acid
DB03435 Uridine-5'-Diphosphate
DB03444 (3e)-6'-Bromo-2,3'-Biindole-2',3(1h,1'h)-Dione 3-Oxime
DB03447 Uridylyl-2'-5'-Phospho-Adenosine
DB03448 2'-Deoxyuridine 3'-Monophosphate
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03463 Para-Xylene
DB03489 2-Keto-3-Deoxygluconate
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03504 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
DB03506 9-Deazaadenine
DB03512 Uridine-2',3'-Vanadate
DB03565 1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine
DB03587 Pyruvoyl Group
DB03611 L-2-Amino-4-Methoxy-Cis-but-3-Enoic Acid
DB03616 Kabiramide C
DB03624 7-(Carboxyamino)-8-Amino-Nonanoic Acid
DB03633 Lpc-Ether
DB03660 Iodo-Phenylalanine
DB03664 P1-(Adenosine-5'-P5-(Uridine-5')Pentaphosphate
DB03666 3'-Azido-3'-Deoxythymidine-5'-Monophosphate
DB03669 4-Fluorophenethyl Alcohol
DB03708 Adenosine-5'-Phosphosulfate
DB03719 N-Ethyl-5'-Carboxamido Adenosine
DB03726 Purine Riboside-5'-Monophosphate
DB03749 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
DB03758 Radicicol
DB03765 Cytidine-2'-Monophosphate
DB03775 D-Dethiobiotin
DB03781 2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid
DB03792 5-Amino-1h-Pyrimidine-2,4-Dione
DB03801 Lysine Nz-Carboxylic Acid
DB03804 5-Bromothienyldeoxyuridine
DB03809 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
DB03830 Phosphorylated Dihydropteroate
DB03842 2-Chloro-6-Methyl-Aniline
DB03845 P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate
DB03850 Jaspisamide A
DB03887 Alpha-Adenosine Monophosphate
DB03899 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
DB03900 2-Methyl-2-Propanol
DB03903 Tmr
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
DB03996 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol
DB04005 Uridine 5'-Triphosphate
DB04014 Alsterpaullone
DB04027 D-Arginine
DB04047 [Pterin-6-Yl Methanyl]-Phosphonophosphate
DB04052 3,4-Dimethylphenol
DB04054 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
DB04068 Fudp
DB04075 N-Acetyl-L-Glutamate
DB04077 Glycerol
DB04078 Isobutylbenzene
DB04120 4-Methyl-1,2-Benzenediol
DB04130 5-Methoxybenzimidazole
DB04137 Guanosine-5'-Triphosphate
DB04139 6-Hydroxypropylthymine
DB04151 4-Methyl-Histidine
DB04158 6-(Adenosine Tetraphosphate-Methyl)-7,8-Dihydropterin
DB04176 Phosporic Acid Mono-[3,4-Dihydroxy-5-(5-Methoxy-Benzoimidazol-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester
DB04179 Benzofuran
DB04214 4-Nitrophenyl Phosphate
DB04254 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
DB04272 Citric Acid
DB04315 Guanosine-5'-Diphosphate
DB04331 Monastrol
DB04345 7,8-dimethylalloxazine
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04377 3-Hydroxy-3-Methyl-Glutaric Acid
DB04395 Phosphoaminophosphonic Acid-Adenylate Ester
DB04444 Tetrafluoroaluminate Ion
DB04447 1,4-Dithiothreitol
DB04456 Trihydroxyarsenite(Iii)
DB04464 N-Formylmethionine
DB04485 Deoxythymidine
DB04505 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
DB04514 Phosphoric Acid-2'-[2'-Deoxy-Uridine]Ester-5'-Guanosine Ester
DB04522 Phosphonoserine
DB04532 Indole
DB04533 2-Amino-P-Cresol
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB04551 Fructose-1,6-Diphosphate
DB04552 Niflumic Acid
DB04554 8-Bromoadenosine-5'-Diphosphate
DB04588 N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
DB04610 7,8-dihydro-6-hydroxymethyl-7-methyl-7-[2-phenylethyl]-pterin
DB04629 Aplyronine A
DB04638 2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE
DB04770 O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL
DB04774 Reidispongiolide A
DB04775 Reidispongiolide C
DB04776 N6-METHYL-(R)-ROSCOVITINE, R-2-[6-(BENZYL-METHYL-AMINO)-9-ISOPROPYL-9H-PURIN-2-YLAMINO]-BUTAN-1-OL
DB04783 Sphinxolide B
DB04868 Nilotinib
DB04941 Crofelemer
DB04953 Ezogabine
DB05039 Indacaterol
DB06210 Eltrombopag
DB06589 Pazopanib
DB06626 Axitinib
DB06693 Mevastatin
DB06781 Difluprednate
DB06846 7-[3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOL-2-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
DB06934 (1R)-3-chloro-1-phenylpropan-1-ol
DB06956 N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
DB06957 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
DB06958 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
DB06961 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide
DB06964 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
DB06969 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
DB07014 2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole
DB07045 (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
DB07058 5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2(3H)-thione
DB07064 (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE
DB07100 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
DB07149 (7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
DB07186 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
DB07234 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
DB07248 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE
DB07266 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one
DB07317 (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
DB07319 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
DB07324 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
DB07325 N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
DB07360 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea
DB07361 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea
DB07362 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
DB07406 (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE
DB07430 (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one
DB07431 (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one
DB07460 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE
DB07468 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07469 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07470 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07495 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
DB07502 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
DB07543 (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
DB07545 N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
DB07584 N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
DB07585 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
DB07594 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL
DB07601 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol
DB07604 (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE
DB07657 PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
DB07676 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one
DB07728 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
DB07801 N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide
DB07812 N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide
DB07836 1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL
DB07859 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
DB07870 (2S)-2-(4-{[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOXY)PROPANOIC ACID
DB07877 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
DB07947 ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
DB08032 N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
DB08033 (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
DB08037 (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
DB08045 4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL
DB08065 2-(1H-pyrazol-3-yl)-1H-benzimidazole
DB08066 N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE
DB08073 (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
DB08080 LATRUNCULIN B
DB08105 N-[(6-BUTOXYNAPHTHALEN-2-YL)SULFONYL]-L-GLUTAMIC ACID
DB08106 N-[(6-BUTOXYNAPHTHALEN-2-YL)SULFONYL]-D-GLUTAMIC ACID
DB08107 N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID
DB08108 N-({6-[(4-CYANOBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID
DB08112 N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID
DB08153 (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE
DB08194 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
DB08197 (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime
DB08198 [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE
DB08239 (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
DB08244 (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE
DB08246 (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
DB08250 (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
DB08276 N-METHYL O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE
DB08292 (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
DB08293 (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
DB08346 (5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE
DB08358 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
DB08436 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
DB08442 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
DB08443 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol
DB08456 3-{[(2,2,5,5-TETRAMETHYL-1-OXO-4-PHENYL-2,5-DIHYDRO-1H-PYRROLIUM-3-YL)METHYL]DISULFANYL}-D-ALANINE
DB08464 METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
DB08465 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE
DB08557 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide
DB08596 5'-deoxy-5'-piperidin-1-ylthymidine
DB08606 (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL
DB08608 4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE
DB08609 (N-{4-[(ETHYLANILINO)SULFONYL]-2-METHYLPHENYL}-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
DB08610 N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE
DB08661 1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
DB08751 N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE
DB08786 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
DB08787 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
DB08788 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
DB08789 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
DB08820 Ivacaftor
DB08860 Pitavastatin
DB08896 Regorafenib
DB08901 Ponatinib
DB08906 Fluticasone furoate
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