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DB02486 - 2-Hydroxyethyl Disulfide


Identification
Name 2-Hydroxyethyl Disulfide
Accession Number DB02486 (EXPT01723)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 154.251
Groups experimental
Monoisotopic Weight 154.012220944
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glutathione S-transferase A1
Name Glutathione S-transferase A1
Gene Name GSTA1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.5843
Lysozyme
Name Lysozyme
Gene Name E
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5505

Enzymes


Glutathione S-transferase A1
Name Glutathione S-transferase A1
Gene Name GSTA1
Actions Not Available
References Not Available
DTHybrid score 0.5843

Predictions


Id Partner name Gene Name Score
3633 Lysozyme R 1.5505
5597 Lysozyme 17 1.5505
1313 Lactoylglutathione lyase GLO1 0.126
904 Glutathione S-transferase P GSTP1 0.0948
901 Glutathione S-transferase Mu 4 GSTM4 0.0853
3759 Glutathione S-transferase gst 0.0666
4541 Glutathione S-transferase GST 0.0666
3932 Glutathione S-transferase A2 GSTA2 0.0566
2264 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT 0.0487
896 Glutathione S-transferase Mu 1 GSTM1 0.0486
4041 Microsomal glutathione S-transferase 2 MGST2 0.0347
5898 Complement C3 C3 0.0299
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0279
766 Beta-2 adrenergic receptor ADRB2 0.0258
6677 Myelin P2 protein PMP2 0.0243
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0239
2517 Subtilisin BPN' apr 0.0231
2457 Bacillolysin nprS 0.0231
1405 Thiopurine S-methyltransferase TPMT 0.0212
2596 Acetyl-CoA acetyltransferase phbA 0.0212
2443 Azurin azu 0.0194
4615 Chain A, Red Copper Protein Nitrosocyanin NE0143 0.0187
4681 Aminopeptidase Not Available 0.018
3526 Pseudomonalisin pcp 0.018
3947 Xanthine dehydrogenase/oxidase XDH 0.0176
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0165
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0165
6231 Pepsin A PGA3 0.0147
5226 Protein ninB ninB 0.014
1758 GTPase HRas HRAS 0.0135
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0122
1277 Alpha-1-antitrypsin SERPINA1 0.0122
6500 Phospholipase A2 PLA2G1B 0.0114
2826 Glucose--fructose oxidoreductase gfo 0.0107
4549 Endonuclease III HP_0602 0.0106
952 Dipeptidyl peptidase 4 DPP4 0.01
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0098
4512 Cytochrome P450 3A4 CYP3A4 0.0091
193 Beta-1 adrenergic receptor ADRB1 0.0067
740 Argininosuccinate synthase ASS1 0.0066
865 Argininosuccinate synthase ASS1 0.0066
2680 Argininosuccinate synthase argG 0.0066
3194 Argininosuccinate synthase argG 0.0066
903 Glutathione S-transferase A5 GSTA5 0.0059
5126 Arginase rocF 0.0058
624 Guanidinoacetate N-methyltransferase GAMT 0.0057
871 Glucocorticoid receptor NR3C1 0.0057
898 Glutathione S-transferase A3 GSTA3 0.0055
900 Glutathione S-transferase A4 GSTA4 0.0052
4034 Glutaredoxin-1 GLRX 0.0051
1928 Leukotriene C4 synthase LTC4S 0.0051
4035 Glutathione S-transferase Mu 5 GSTM5 0.0051
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0051
906 Glutathione peroxidase 1 GPX1 0.0051
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0051
4036 Glutathione peroxidase 6 GPX6 0.0051
4037 Hypothetical protein GPX1 0.0051
4297 Hypothetical protein SP_1951 0.0051
4521 Hypothetical protein BC_2969 0.0051
4540 Hypothetical protein TM_1070 0.0051
4555 Hypothetical protein MT1739 0.0051
4569 Hypothetical protein mshD 0.0051
4578 Hypothetical protein PA3270 0.0051
4747 Hypothetical protein PA3967 0.0051
5177 Hypothetical protein TM_0096 0.0051
5194 Hypothetical protein PA1204 0.0051
5240 Hypothetical protein Rv2991 0.0051
5370 Hypothetical protein TM_1158 0.0051
5710 Hypothetical protein Tb927.5.1360 0.0051
4029 Microsomal glutathione S-transferase 3 MGST3 0.0051
4032 Microsomal glutathione S-transferase 1 MGST1 0.0051
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0051
4040 Glutathione peroxidase 7 GPX7 0.0051
907 Glutathione peroxidase 2 GPX2 0.0051
4038 Glutathione peroxidase 4 GPX4 0.0051
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0051
910 Epididymal secretory glutathione peroxidase GPX5 0.0051
911 Glutathione peroxidase 3 GPX3 0.0051
4042 Glutathione transferase omega-2 GSTO2 0.0051
4033 S-formylglutathione hydrolase ESD 0.0051
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0051
897 Glutathione S-transferase kappa 1 GSTK1 0.0048
3319 Hydroxyacylglutathione hydrolase HAGH 0.0048
909 Maleylacetoacetate isomerase GSTZ1 0.0047
5682 Ribonuclease pancreatic RNASE1 0.0047
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0045
6016 Cytochrome P450 2C19 CYP2C19 0.0045
1588 Multidrug resistance protein 1 ABCB1 0.0044
2165 Glutathione S-transferase Mu 2 GSTM2 0.0043
4119 Cytochrome P450 2D6 CYP2D6 0.0043
899 Glutathione S-transferase Mu 3 GSTM3 0.004
905 Glutathione transferase omega-1 GSTO1 0.0039
207 Glutathione synthetase GSS 0.0037
5269 Glutathione synthetase gshB 0.0037
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0035
833 Organic cation/carnitine transporter 1 SLC22A4 0.0034
6147 Solute carrier family 22 member 3 SLC22A3 0.0033
714 Glutathione reductase, mitochondrial GSR 0.0032
908 Glutathione S-transferase theta-1 GSTT1 0.003
118 Organic cation/carnitine transporter 2 SLC22A5 0.003
6144 Solute carrier family 22 member 2 SLC22A2 0.0028
6142 Solute carrier family 22 member 8 SLC22A8 0.0028
6145 Solute carrier family 22 member 1 SLC22A1 0.0028
6136 Multidrug resistance-associated protein 5 ABCC5 0.0024
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0022
2164 Multidrug resistance-associated protein 4 ABCC4 0.002
862 Multidrug resistance-associated protein 1 ABCC1 0.0019
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0018
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