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Pseudomonalisin


Partner ID 3526
Name Pseudomonalisin
Synonyms 5567
Gene name pcp
General function Not Available
Specific function Hydrolysis of the B chain of insulin at 13- Glu-|-Ala-14, 15-Leu-|-Tyr-16 and 25-Phe-|-Tyr-26 and angiotensin I at 4-Tyr-|-Ile-5. A good synthetic substrate is Lys-Pro-Ile-Glu- Phe-|-Phe(NO(2))-Arg-Leu
Gene sequence + ...

ATGAAGTCGTCAGCCGCAAAACAAACGGTCCTGTGTCTAAACCGTTACGCGGTCGTTGCTTTGCCTCTCGCTATTGCTTCGTTCGCTGCGTTCGGCGCATCGCCCGCGTCCACACTGTGGGCGCCCACCGACACGAAGGCGTTTGTAACGCCCGCCCAGGTCGAGGCGCGCAGTGCGGCGCCGTTGCTCGAACTCGCCGCCGGCGAGACCGCGCATATCGTCGTCAGCCTCAAGCTTCGCGACGAGGCGCAACTGAAGCAACTCGCGCAGGCAGTCAACCAGCCGGGCAACGCGCAGTTCGGCAAATTCCTCAAGCGTCGGCAATTCCTCTCGCAATTCGCGCCGACCGAGGCGCAAGTGCAGGCCGTCGTCGCGCATTTACGGAAGAACGGCTTCGTCAACATTCACGTCGTGCCGAACCGCCTGCTGATTTCCGCCGACGGCAGCGCCGGCGCCGTCAAAGCGGCCTTCAACACGCCGCTGGTTCGCTATCAGCTGAACGGCAAGGCCGGCTACGCGAACACGGCGCCGGCACAGGTGCCGCAGGATCTCGGCGAGATCGTCGGTTCGGTGCTCGGCTTGCAGAACGTCACGCGTGCCCATCCGATGCTGAAGGTCGGCGAGCGTTCCGCCGCGAAGACGCTGGCCGCCGGTACGGCCAAGGGCCACAATCCGACCGAGTTCCCAACGATCTACGACGCCAGCAGCGCGCCCACCGCGGCGAACACGACGGTCGGCATCATCACGATCGGCGGCGTCTCGCAGACGCTTCAGGATCTCCAGCAGTTCACCAGCGCGAATGGCCTTGCGTCCGTCAACACGCAGACGATCCAGACCGGATCGTCGAATGGCGACTACAGCGACGATCAGCAAGGCCAGGGTGAGTGGGACCTCGACAGCCAGTCGATTGTCGGTTCCGCGGGCGGCGCGGTGCAGCAACTGCTGTTCTACATGGCCGATCAAAGCGCGTCCGGCAACACCGGCCTCACGCAGGCGTTCAATCAGGCGGTGTCCGATAACGTCGCGAAGGTGATCAACGTGTCGCTCGGCTGGTGTGAAGCCGATGCCAACGCTGACGGCACGCTGCAGGCCGAAGATCGCATCTTCGCGACGGCCGCGGCACAAGGGCAAACCTTCTCGGTGTCGTCCGGCGATGAGGGCGTGTACGAATGCAACAACCGCGGCTACCCTGACGGCAGCACCTATTCGGTATCGTGGCCGGCCTCGTCGCCCAACGTGATCGCCGTCGGCGGCACGACGCTTTACACGACGTCAGCAGGCGCCTACTCGAACGAAACCGTCTGGAACGAAGGGCTCGACAGCAACGGCAAGCTCTGGGCAACCGGCGGTGGCTACAGCGTGTACGAGTCGAAGCCGTCGTGGCAGTCGGTGGTGAGCGGCACGCCGGGCCGGCGTCTGCTACCCGACATCTCCTTCGACGCGGCGCAGGGCACGGGCGCACTGATTTACAACTACGGCCAGCTTCAGCAGATCGGCGGGACGAGCCTCGCTTCGCCAATCTTCGTCGGGCTGTGGGCACGTTTGCAGAGCGCGAATTCGAATAGCCTGGGCTTCCCCGCAGCCAGCTTTTACAGCGCCATTAGCTCGACGCCTTCGCTGGTGCACGACGTGAAATCGGGTAACAACGGCTACGGCGGCTATGGTTACAACGCAGGCACCGGTTGGGACTATCCGACCGGATGGGGAAGCCTCGATATTGCGAAGCTGTCCGCTTATATCAGGAGCAACGGCTTTGGACATTGA
Protein sequence + ...

MKSSAAKQTVLCLNRYAVVALPLAIASFAAFGASPASTLWAPTDTKAFVTPAQVEARSAAPLLELAAGETAHIVVSLKLRDEAQLKQLAQAVNQPGNAQFGKFLKRRQFLSQFAPTEAQVQAVVAHLRKNGFVNIHVVPNRLLISADGSAGAVKAAFNTPLVRYQLNGKAGYANTAPAQVPQDLGEIVGSVLGLQNVTRAHPMLKVGERSAAKTLAAGTAKGHNPTEFPTIYDASSAPTAANTTVGIITIGGVSQTLQDLQQFTSANGLASVNTQTIQTGSSNGDYSDDQQGQGEWDLDSQSIVGSAGGAVQQLLFYMADQSASGNTGLTQAFNQAVSDNVAKVINVSLGWCEADANADGTLQAEDRIFATAAAQGQTFSVSSGDEGVYECNNRGYPDGSTYSVSWPASSPNVIAVGGTTLYTTSAGAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSVVSGTPGRRLLPDISFDAAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQSANSNSLGFPAASFYSAISSTPSLVHDVKSGNNGYGGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
GO Classification Not Available
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB03660 Iodo-Phenylalanine
DB03750 Isovaleric Acid
DB03978 Tyrosinal

Associated as Prediction

Id Name
DB00135 L-Tyrosine
DB00364 Sucralfate
DB00373 Timolol
DB00536 Guanidine
DB01076 Atorvastatin
DB01261 Sitagliptin
DB01639 N-Methyl-Pyridoxal-5'-Phosphate
DB01722 Ethylbenzene
DB01766 Beta-(2-Naphthyl)-Alanine
DB01845 N-Butylbenzene
DB01884 2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One
DB01932 5-Methylpyrrole
DB01957 3-Chlorophenol
DB01986 3-Fluoro-2-Methyl-Aniline
DB02004 5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine
DB02024 3-phenylpropionic acid
DB02210 Hexane-1,6-Diol
DB02403 2-Fluoroaniline
DB02406 N-Valeric Acid
DB02467 S-Oxymethionine
DB02486 2-Hydroxyethyl Disulfide
DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
DB02531 Isobutyric Acid
DB02534 2-Allylphenol
DB02758 Indolylpropionic Acid
DB02815 Indene
DB02870 N-Allyl-Aniline
DB02926 2-Oxo-Glutaric Acid
DB02944 Alpha-D-Mannose
DB02970 2-Propyl-Aniline
DB02981 Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
DB03029 Ortho-Xylene
DB03238 3,5-Difluoroaniline
DB03253 (2s)-Pyrrolidin-2-Ylmethylamine
DB03255 Phenol
DB03301 2-Allyl-6-Methyl-Phenol
DB03345 Beta-Mercaptoethanol
DB03463 Para-Xylene
DB03553 Glutaric Acid
DB03568 Butanoic Acid
DB03629 Pyridoxal-5'-Phosphate-N-Oxide
DB03660 Iodo-Phenylalanine
DB03662 Vitamin B6 Complexed with 2-Amino-Pentanoic Acid
DB03669 4-Fluorophenethyl Alcohol
DB03741 2-Methylbutanoic Acid
DB03750 Isovaleric Acid
DB03766 Propanoic Acid
DB03793 Benzoic Acid
DB03842 2-Chloro-6-Methyl-Aniline
DB03978 Tyrosinal
DB04078 Isobutylbenzene
DB04083 N'-Pyridoxyl-Lysine-5'-Monophosphate
DB04179 Benzofuran
DB04299 Maleic Acid
DB04467 Pyridoxyl-Alanine-5-Phosphate
DB04491 Diisopropylphosphono Group
DB04532 Indole
DB04577 1-(1-phenylcyclopentyl)methylamine
DB04578 (S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
DB04713 4-IODOPHENYLALANINE
DB04762 N-PYRIDOXYL-D-GLUTAMIC ACID-5'-MONOPHOSPHATE
DB04765 N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE
DB04876 Vildagliptin
DB06203 Alogliptin
DB06335 Saxagliptin
DB06655 Liraglutide
DB06839 N-(ethoxycarbonyl)-L-leucine
DB06880 (1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE
DB06934 (1R)-3-chloro-1-phenylpropan-1-ol
DB06939 N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE
DB06993 (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine
DB06994 (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine
DB07015 (3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine
DB07021 (7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine
DB07067 (2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE
DB07072 (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
DB07081 (2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
DB07092 (2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE
DB07135 (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE
DB07154 (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE
DB07181 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide
DB07193 (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine
DB07205 N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
DB07239 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile
DB07271 (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE
DB07328 METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE
DB07356 (1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE
DB07412 1-biphenyl-2-ylmethanamine
DB07465 (1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile
DB07482 (2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE
DB07543 (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
DB07666 (3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE
DB07779 N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE
DB07830 (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE
DB07851 (3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE
DB08024 1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE
DB08044 (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE
DB08051 (2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
DB08164 (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE
DB08288 CYCLOHEXYL-NORSTATINE
DB08371 PARA-(BENZOYL)-PHENYLALANINE
DB08382 2-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidine
DB08429 N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide
DB08445 (3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE
DB08456 3-{[(2,2,5,5-TETRAMETHYL-1-OXO-4-PHENYL-2,5-DIHYDRO-1H-PYRROLIUM-3-YL)METHYL]DISULFANYL}-D-ALANINE
DB08504 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM
DB08530 7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE
DB08588 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE
DB08617 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE
DB08672 4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE
DB08740 CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE
DB08743 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE
DB08882 Linagliptin
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