DT-Web

DB07543 - (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol


Identification
Name (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
Accession Number DB07543
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 298.3795
Groups experimental
Monoisotopic Weight 298.168127958
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Lysozyme
Name Lysozyme
Gene Name E
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.506
Beta-2 adrenergic receptor
Name Beta-2 adrenergic receptor
Gene Name ADRB2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.4861

Predictions


Id Partner name Gene Name Score
3633 Lysozyme R 1.506
5597 Lysozyme 17 1.506
193 Beta-1 adrenergic receptor ADRB1 0.2262
1517 Beta-3 adrenergic receptor ADRB3 0.0648
4119 Cytochrome P450 2D6 CYP2D6 0.0587
2264 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT 0.0487
4031 Glutathione S-transferase A1 GSTA1 0.0315
556 Alpha-1A adrenergic receptor ADRA1A 0.0293
3923 Cholinesterase BCHE 0.028
1588 Multidrug resistance protein 1 ABCB1 0.0253
320 5-hydroxytryptamine 1A receptor HTR1A 0.0245
2457 Bacillolysin nprS 0.0231
4512 Cytochrome P450 3A4 CYP3A4 0.0204
6144 Solute carrier family 22 member 2 SLC22A2 0.0197
6016 Cytochrome P450 2C19 CYP2C19 0.0192
4615 Chain A, Red Copper Protein Nitrosocyanin NE0143 0.0187
318 Alpha-2A adrenergic receptor ADRA2A 0.0186
4681 Aminopeptidase Not Available 0.018
3526 Pseudomonalisin pcp 0.018
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0165
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0165
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.016
6231 Pepsin A PGA3 0.0147
5226 Protein ninB ninB 0.014
885 5-hydroxytryptamine 1B receptor HTR1B 0.0137
1758 GTPase HRas HRAS 0.0135
6145 Solute carrier family 22 member 1 SLC22A1 0.0128
4200 Cytochrome P450 1A2 CYP1A2 0.0125
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0122
1277 Alpha-1-antitrypsin SERPINA1 0.0122
6500 Phospholipase A2 PLA2G1B 0.0114
629 Alpha-2B adrenergic receptor ADRA2B 0.0113
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0109
2826 Glucose--fructose oxidoreductase gfo 0.0107
4549 Endonuclease III HP_0602 0.0106
3810 Catechol O-methyltransferase COMT 0.0101
632 Alpha-1B adrenergic receptor ADRA1B 0.01
952 Dipeptidyl peptidase 4 DPP4 0.01
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0098
378 Alpha-2C adrenergic receptor ADRA2C 0.0096
5718 Cytochrome P450 2A6 CYP2A6 0.0094
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0089
4757 Cytochrome P450 2C9 CYP2C9 0.0088
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0086
1313 Lactoylglutathione lyase GLO1 0.0084
6147 Solute carrier family 22 member 3 SLC22A3 0.0083
6024 Cytochrome P450 1A1 CYP1A1 0.0081
1820 Beta-nerve growth factor NGF 0.0081
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0074
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0074
828 Phenylalanine-4-hydroxylase PAH 0.0071
3109 Phenylalanine-4-hydroxylase phhA 0.0071
118 Organic cation/carnitine transporter 2 SLC22A5 0.0067
740 Argininosuccinate synthase ASS1 0.0066
865 Argininosuccinate synthase ASS1 0.0066
2680 Argininosuccinate synthase argG 0.0066
3194 Argininosuccinate synthase argG 0.0066
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0063
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.006
5126 Arginase rocF 0.0058
624 Guanidinoacetate N-methyltransferase GAMT 0.0057
871 Glucocorticoid receptor NR3C1 0.0057
789 Alpha-1D adrenergic receptor ADRA1D 0.0057
824 Sodium-dependent serotonin transporter SLC6A4 0.0057
777 Tumor necrosis factor TNF 0.0054
6107 Cytochrome P450 3A7 CYP3A7 0.0051
713 Sodium-dependent dopamine transporter SLC6A3 0.0051
3941 Amine oxidase [flavin-containing] A MAOA 0.0051
4118 Cytochrome P450 3A5 CYP3A5 0.0049
5682 Ribonuclease pancreatic RNASE1 0.0047
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0045
833 Organic cation/carnitine transporter 1 SLC22A4 0.0043
1176 Mitogen-activated protein kinase 1 MAPK1 0.004
4924 Cytochrome P450 2C8 CYP2C8 0.0036
1374 Natriuretic peptides B NPPB 0.0029
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0029
1827 Gap junction alpha-1 protein GJA1 0.0029
1908 Vascular cell adhesion protein 1 VCAM1 0.0029
6142 Solute carrier family 22 member 8 SLC22A8 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
465 Calmodulin CALM1 0.0028
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0026
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0024
183 Vascular endothelial growth factor A VEGFA 0.0022
3939 Amine oxidase [flavin-containing] B MAOB 0.0022
6151 Monocarboxylate transporter 10 SLC16A10 0.0019
1360 Sphingomyelin phosphodiesterase SMPD1 0.0018
6013 Cytochrome P450 2E1 CYP2E1 0.0018
502 5-hydroxytryptamine 2A receptor HTR2A 0.0017
492 Histamine H1 receptor HRH1 0.0017
3947 Xanthine dehydrogenase/oxidase XDH 0.0015
1256 5-hydroxytryptamine 6 receptor HTR6 0.0015
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0014
124 Histamine H2 receptor HRH2 0.0013
716 5-hydroxytryptamine 7 receptor HTR7 0.0013
6432 Transporter snf 0.0013
436 5-hydroxytryptamine 2B receptor HTR2B 0.0012
432 D(4) dopamine receptor DRD4 0.0012
638 D(3) dopamine receptor DRD3 0.0012
20 Prostaglandin G/H synthase 1 PTGS1 0.0012
590 5-hydroxytryptamine 2C receptor HTR2C 0.0011
23 D(1A) dopamine receptor DRD1 0.001
831 D(2) dopamine receptor DRD2 0.001
6106 Cytochrome P450 2C18 CYP2C18 0.0009
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0009
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0009
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0008
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0008
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0007
6030 Cytochrome P450 2B6 CYP2B6 0.0007
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