DT-Web

DB08112 - N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID


Identification
Name N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID
Accession Number DB08112
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 486.47
Groups experimental
Monoisotopic Weight 486.089699867
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


UDP-N-acetylmuramoylalanine--D-glutamate ligase
Name UDP-N-acetylmuramoylalanine--D-glutamate ligase
Gene Name murD
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3471

Predictions


Id Partner name Gene Name Score
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.1302
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.1179
4819 Hydrolase Not Available 0.0155
5249 Hydrolase Not Available 0.0155
5436 Hydrolase Not Available 0.0155
3168 Beta-lactamase OXA-1 bla 0.0155
3122 D-hydantoinase Not Available 0.0155
3145 D-hydantoinase hyuA 0.0155
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0155
3237 Beta-lactamase OXA-2 bla 0.0135
3292 Alanine racemase, catabolic dadX 0.0135
3281 Isoaspartyl dipeptidase iadA 0.0135
4264 Alpha-L-fucosidase, putative TM_0306 0.0135
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0124
4549 Endonuclease III HP_0602 0.0117
2646 Dihydroorotase pyrC 0.0117
2717 Folylpolyglutamate synthase fgs 0.0112
2340 Beta-lactamase PSE-2 bla 0.0107
2796 Parathion hydrolase opd 0.0105
6539 Parathion hydrolase opd 0.0105
894 Alanine racemase alr 0.0102
2453 Alanine racemase alr 0.0102
2240 Cell division protein kinase 2 CDK2 0.0058
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0028
5293 Shikimate kinase 2 aroL 0.0028
5287 Signaling protein Not Available 0.0028
5288 Shikimate kinase aroK 0.0028
5292 Putative partitioning protein TT_C1605 0.0028
5304 UPF0166 protein TM_0021 TM_0021 0.0028
4346 Polynucleotide kinase pseT 0.0028
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0028
5266 Activator of hgdC 0.0028
3199 Phosphopantetheine adenylyltransferase coaD 0.0028
3543 Phosphopantetheine adenylyltransferase coaD 0.0028
3567 Phosphopantetheine adenylyltransferase coaD 0.0028
5289 Phosphopantetheine adenylyltransferase coaD 0.0028
2874 Nitrogenase iron protein 1 nifH1 0.0028
5283 D-alanine--D-alanine ligase B ddlB 0.0028
5281 Plasmid segregation protein parM parM 0.0028
5299 D-alanine--D-alanine ligase ddl 0.0028
6598 D-alanine--D-alanine ligase ddl 0.0028
5276 Chromosomal replication initiator protein dnaA dnaA 0.0028
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0028
5308 Preprotein translocase secA 1 subunit secA1 0.0028
5259 Transcriptional regulator ntrC1 0.0028
6699 Transcriptional regulator Cgl2612 0.0028
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0028
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0028
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0028
5291 Glycogen synthase 1 glgA1 0.0028
5264 DNA replication protein REP 0.0028
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0028
5315 Chaperone protein htpG htpG 0.0028
5284 Large T antigen Not Available 0.0028
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0028
5277 Preprotein translocase subunit secA secA 0.0028
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0028
5285 Kinesin heavy chain KIF5B 0.0028
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0028
5261 Phosphoribosylformylglycinamidine synthase purL 0.0028
2270 Dephospho-CoA kinase coaE 0.0024
3470 Hypothetical protein MG245 homolog MPN_348 0.0024
4106 Guanylate kinase GUK1 0.0024
4516 Guanylate kinase gmk 0.0024
4837 Cag-alfa cag-alfa 0.0024
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0024
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0024
2284 Adenylate kinase adk 0.0024
2296 Adenylate kinase adk 0.0024
2311 Adenylate kinase adk 0.0024
2312 Adenylate kinase Not Available 0.0024
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0024
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0024
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0024
5302 TrwB trwB 0.0024
4774 NTPase P4 Not Available 0.0024
3175 Glutamate--cysteine ligase gshA 0.0024
5646 Galactokinase GALK1 0.0024
3426 Glutamine synthetase glnA 0.0024
3987 Glutamine synthetase GLUL 0.0024
413 Amidophosphoribosyltransferase PPAT 0.0024
2515 Amidophosphoribosyltransferase purF 0.0024
3714 Amidophosphoribosyltransferase purF 0.0024
4839 DNA polymerase III subunit tau dnaX 0.0024
5265 FtsH ftsH 0.0024
6277 Heat shock cognate 71 kDa protein HSPA8 0.0024
5189 Trimethylamine dehydrogenase tmd 0.0024
4838 PMS1 protein homolog 2 PMS2 0.0024
2390 Nonsecretory ribonuclease RNASE2 0.0022
2683 Mono-ADP-ribosyltransferase C3 C3 0.0022
2922 Glycerol kinase glpK 0.0022
5271 Focal adhesion kinase 1 PTK2 0.0022
5312 Kinesin-like protein KIF1A KIF1A 0.0022
3669 Ribokinase rbsK 0.0021
2892 Acetylglutamate kinase argB 0.0021
3550 Acetylglutamate kinase argB 0.0021
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0021
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0021
2371 Pantothenate kinase coaA 0.0021
825 Arsenical pump-driving ATPase ASNA1 0.0021
3435 Arsenical pump-driving ATPase arsA 0.0021
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0021
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0021
1881 Hexokinase-1 HK1 0.0021
2615 Chemotaxis protein cheA cheA 0.0021
340 Apoptotic protease-activating factor 1 APAF1 0.002
5300 Antigen peptide transporter 1 TAP1 0.002
2727 S-adenosylmethionine synthetase metK 0.002
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.002
2282 Protein recA recA 0.002
2315 Protein recA recA 0.002
2332 Protein recA recA 0.002
5263 Protein recA recA 0.002
408 Riboflavin kinase RFK 0.002
2334 Dethiobiotin synthetase bioD 0.0019
6555 Dethiobiotin synthetase bioD 0.0019
2697 Uridine-cytidine kinase 2 UCK2 0.0019
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0019
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0019
788 Creatine kinase M-type CKM 0.0019
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0019
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0019
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0019
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0019
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0018
6395 Myosin-14 MYH14 0.0018
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0018
2091 Endoplasmin HSP90B1 0.0017
2251 Thymidylate kinase tmk 0.0017
2254 Thymidylate kinase DTYMK 0.0017
3522 Thymidylate kinase tmk 0.0017
48 Pyridoxal kinase PDXK 0.0017
1422 Serine/threonine-protein kinase 6 AURKA 0.0017
702 UMP-CMP kinase CMPK1 0.0017
3379 Kinesin-like protein KIF11 KIF11 0.0017
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0017
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0016
3822 Actin, alpha skeletal muscle ACTA1 0.0016
207 Glutathione synthetase GSS 0.0016
5269 Glutathione synthetase gshB 0.0016
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0016
504 Mast/stem cell growth factor receptor KIT 0.0015
509 Thymidine kinase TK 0.0015
570 Thymidine kinase TK 0.0015
2559 Thymidine kinase TK 0.0015
3430 Thymidine kinase tdk 0.0015
3518 Thymidine kinase TK 0.0015
5301 Thymidine kinase tdk 0.0015
5771 Thymidine kinase ORF36 0.0015
7009 Thymidine kinase ORF36 0.0015
1721 Glycogen synthase kinase-3 beta GSK3B 0.0015
5294 Nucleoside diphosphate kinase A NME1 0.0015
5682 Ribonuclease pancreatic RNASE1 0.0014
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0013
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0013
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0013
4773 Deoxycytidine kinase DCK 0.0012
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