DT-Web

DB07045 - (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol


Identification
Name (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Accession Number DB07045
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 441.269
Groups experimental
Monoisotopic Weight 440.076658508
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


BAG family molecular chaperone regulator 1
Name BAG family molecular chaperone regulator 1
Gene Name BAG1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4891
Heat shock cognate 71 kDa protein
Name Heat shock cognate 71 kDa protein
Gene Name HSPA8
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2508

Predictions


Id Partner name Gene Name Score
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0103
5287 Signaling protein Not Available 0.0092
3199 Phosphopantetheine adenylyltransferase coaD 0.0092
3543 Phosphopantetheine adenylyltransferase coaD 0.0092
3567 Phosphopantetheine adenylyltransferase coaD 0.0092
5289 Phosphopantetheine adenylyltransferase coaD 0.0092
5288 Shikimate kinase aroK 0.0092
5276 Chromosomal replication initiator protein dnaA dnaA 0.0092
5304 UPF0166 protein TM_0021 TM_0021 0.0092
5281 Plasmid segregation protein parM parM 0.0092
5292 Putative partitioning protein TT_C1605 0.0092
5266 Activator of hgdC 0.0092
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0092
5259 Transcriptional regulator ntrC1 0.0092
6699 Transcriptional regulator Cgl2612 0.0092
2874 Nitrogenase iron protein 1 nifH1 0.0092
4346 Polynucleotide kinase pseT 0.0092
5283 D-alanine--D-alanine ligase B ddlB 0.0092
5293 Shikimate kinase 2 aroL 0.0092
5264 DNA replication protein REP 0.0092
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0092
5299 D-alanine--D-alanine ligase ddl 0.0092
6598 D-alanine--D-alanine ligase ddl 0.0092
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0092
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0092
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0092
5291 Glycogen synthase 1 glgA1 0.0092
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0092
5308 Preprotein translocase secA 1 subunit secA1 0.0092
5315 Chaperone protein htpG htpG 0.0092
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0092
5284 Large T antigen Not Available 0.0092
5285 Kinesin heavy chain KIF5B 0.0092
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0092
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0092
5261 Phosphoribosylformylglycinamidine synthase purL 0.0092
5277 Preprotein translocase subunit secA secA 0.0092
3470 Hypothetical protein MG245 homolog MPN_348 0.008
4106 Guanylate kinase GUK1 0.008
4516 Guanylate kinase gmk 0.008
3390 Aminoglycoside 3'-phosphotransferase aphA 0.008
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.008
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.008
4774 NTPase P4 Not Available 0.008
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.008
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.008
2270 Dephospho-CoA kinase coaE 0.008
413 Amidophosphoribosyltransferase PPAT 0.008
2515 Amidophosphoribosyltransferase purF 0.008
3714 Amidophosphoribosyltransferase purF 0.008
2284 Adenylate kinase adk 0.008
2296 Adenylate kinase adk 0.008
2311 Adenylate kinase adk 0.008
2312 Adenylate kinase Not Available 0.008
5646 Galactokinase GALK1 0.008
5265 FtsH ftsH 0.008
4837 Cag-alfa cag-alfa 0.008
5189 Trimethylamine dehydrogenase tmd 0.008
3426 Glutamine synthetase glnA 0.008
3987 Glutamine synthetase GLUL 0.008
5302 TrwB trwB 0.008
3175 Glutamate--cysteine ligase gshA 0.008
4838 PMS1 protein homolog 2 PMS2 0.008
4839 DNA polymerase III subunit tau dnaX 0.008
340 Apoptotic protease-activating factor 1 APAF1 0.0076
2683 Mono-ADP-ribosyltransferase C3 C3 0.0074
2390 Nonsecretory ribonuclease RNASE2 0.0074
2922 Glycerol kinase glpK 0.0074
5271 Focal adhesion kinase 1 PTK2 0.0074
5312 Kinesin-like protein KIF1A KIF1A 0.0074
5300 Antigen peptide transporter 1 TAP1 0.0073
2282 Protein recA recA 0.0071
2315 Protein recA recA 0.0071
2332 Protein recA recA 0.0071
5263 Protein recA recA 0.0071
408 Riboflavin kinase RFK 0.0071
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.007
3669 Ribokinase rbsK 0.007
2371 Pantothenate kinase coaA 0.007
825 Arsenical pump-driving ATPase ASNA1 0.007
3435 Arsenical pump-driving ATPase arsA 0.007
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.007
2615 Chemotaxis protein cheA cheA 0.007
2892 Acetylglutamate kinase argB 0.007
3550 Acetylglutamate kinase argB 0.007
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.007
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.007
1881 Hexokinase-1 HK1 0.007
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0067
2727 S-adenosylmethionine synthetase metK 0.0067
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0067
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0067
788 Creatine kinase M-type CKM 0.0066
2334 Dethiobiotin synthetase bioD 0.0064
6555 Dethiobiotin synthetase bioD 0.0064
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0064
2697 Uridine-cytidine kinase 2 UCK2 0.0064
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0063
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0063
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0063
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0063
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0061
48 Pyridoxal kinase PDXK 0.006
702 UMP-CMP kinase CMPK1 0.006
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0059
6395 Myosin-14 MYH14 0.0059
2091 Endoplasmin HSP90B1 0.0059
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0059
2251 Thymidylate kinase tmk 0.0059
2254 Thymidylate kinase DTYMK 0.0059
3522 Thymidylate kinase tmk 0.0059
207 Glutathione synthetase GSS 0.0058
5269 Glutathione synthetase gshB 0.0058
1422 Serine/threonine-protein kinase 6 AURKA 0.0057
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0057
3379 Kinesin-like protein KIF11 KIF11 0.0056
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0055
3822 Actin, alpha skeletal muscle ACTA1 0.0054
504 Mast/stem cell growth factor receptor KIT 0.0054
509 Thymidine kinase TK 0.0052
570 Thymidine kinase TK 0.0052
2559 Thymidine kinase TK 0.0052
3430 Thymidine kinase tdk 0.0052
3518 Thymidine kinase TK 0.0052
5301 Thymidine kinase tdk 0.0052
5771 Thymidine kinase ORF36 0.0052
7009 Thymidine kinase ORF36 0.0052
5294 Nucleoside diphosphate kinase A NME1 0.0052
1721 Glycogen synthase kinase-3 beta GSK3B 0.005
4773 Deoxycytidine kinase DCK 0.005
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0048
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0048
5682 Ribonuclease pancreatic RNASE1 0.0047
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0043
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