DT-Web

DB08198 - [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE


Identification
Name [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE
Accession Number DB08198
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 338.423
Groups experimental
Monoisotopic Weight 338.10889852
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Kinesin-like protein KIF11
Name Kinesin-like protein KIF11
Gene Name KIF11
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8349

Predictions


Id Partner name Gene Name Score
5285 Kinesin heavy chain KIF5B 0.0022
5287 Signaling protein Not Available 0.0022
5291 Glycogen synthase 1 glgA1 0.0022
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0022
3199 Phosphopantetheine adenylyltransferase coaD 0.0022
3543 Phosphopantetheine adenylyltransferase coaD 0.0022
3567 Phosphopantetheine adenylyltransferase coaD 0.0022
5289 Phosphopantetheine adenylyltransferase coaD 0.0022
5293 Shikimate kinase 2 aroL 0.0022
5288 Shikimate kinase aroK 0.0022
5304 UPF0166 protein TM_0021 TM_0021 0.0022
5281 Plasmid segregation protein parM parM 0.0022
2874 Nitrogenase iron protein 1 nifH1 0.0022
5292 Putative partitioning protein TT_C1605 0.0022
5276 Chromosomal replication initiator protein dnaA dnaA 0.0022
5266 Activator of hgdC 0.0022
4346 Polynucleotide kinase pseT 0.0022
5283 D-alanine--D-alanine ligase B ddlB 0.0022
5259 Transcriptional regulator ntrC1 0.0022
6699 Transcriptional regulator Cgl2612 0.0022
5264 DNA replication protein REP 0.0022
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0022
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0022
5299 D-alanine--D-alanine ligase ddl 0.0022
6598 D-alanine--D-alanine ligase ddl 0.0022
5315 Chaperone protein htpG htpG 0.0022
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0022
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0022
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0022
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0022
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0022
5277 Preprotein translocase subunit secA secA 0.0022
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0022
5308 Preprotein translocase secA 1 subunit secA1 0.0022
5284 Large T antigen Not Available 0.0022
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0022
5261 Phosphoribosylformylglycinamidine synthase purL 0.0022
3470 Hypothetical protein MG245 homolog MPN_348 0.0019
4106 Guanylate kinase GUK1 0.0019
4516 Guanylate kinase gmk 0.0019
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0019
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0019
2270 Dephospho-CoA kinase coaE 0.0019
2284 Adenylate kinase adk 0.0019
2296 Adenylate kinase adk 0.0019
2311 Adenylate kinase adk 0.0019
2312 Adenylate kinase Not Available 0.0019
3426 Glutamine synthetase glnA 0.0019
3987 Glutamine synthetase GLUL 0.0019
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0019
5302 TrwB trwB 0.0019
4837 Cag-alfa cag-alfa 0.0019
4774 NTPase P4 Not Available 0.0019
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0019
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0019
5646 Galactokinase GALK1 0.0019
413 Amidophosphoribosyltransferase PPAT 0.0019
2515 Amidophosphoribosyltransferase purF 0.0019
3714 Amidophosphoribosyltransferase purF 0.0019
3175 Glutamate--cysteine ligase gshA 0.0019
4838 PMS1 protein homolog 2 PMS2 0.0019
5265 FtsH ftsH 0.0019
4839 DNA polymerase III subunit tau dnaX 0.0019
6277 Heat shock cognate 71 kDa protein HSPA8 0.0019
5189 Trimethylamine dehydrogenase tmd 0.0019
2683 Mono-ADP-ribosyltransferase C3 C3 0.0018
2390 Nonsecretory ribonuclease RNASE2 0.0018
5312 Kinesin-like protein KIF1A KIF1A 0.0018
2922 Glycerol kinase glpK 0.0018
5271 Focal adhesion kinase 1 PTK2 0.0018
3669 Ribokinase rbsK 0.0017
2892 Acetylglutamate kinase argB 0.0017
3550 Acetylglutamate kinase argB 0.0017
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0017
2371 Pantothenate kinase coaA 0.0017
825 Arsenical pump-driving ATPase ASNA1 0.0017
3435 Arsenical pump-driving ATPase arsA 0.0017
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0017
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0017
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0017
1881 Hexokinase-1 HK1 0.0017
2615 Chemotaxis protein cheA cheA 0.0017
2727 S-adenosylmethionine synthetase metK 0.0016
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0016
5300 Antigen peptide transporter 1 TAP1 0.0016
340 Apoptotic protease-activating factor 1 APAF1 0.0016
408 Riboflavin kinase RFK 0.0016
2282 Protein recA recA 0.0016
2315 Protein recA recA 0.0016
2332 Protein recA recA 0.0016
5263 Protein recA recA 0.0016
2697 Uridine-cytidine kinase 2 UCK2 0.0015
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0015
2334 Dethiobiotin synthetase bioD 0.0015
6555 Dethiobiotin synthetase bioD 0.0015
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0015
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0015
788 Creatine kinase M-type CKM 0.0015
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0015
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0015
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0015
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0015
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0014
6395 Myosin-14 MYH14 0.0014
2091 Endoplasmin HSP90B1 0.0014
48 Pyridoxal kinase PDXK 0.0014
1422 Serine/threonine-protein kinase 6 AURKA 0.0014
2251 Thymidylate kinase tmk 0.0014
2254 Thymidylate kinase DTYMK 0.0014
3522 Thymidylate kinase tmk 0.0014
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0014
702 UMP-CMP kinase CMPK1 0.0013
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0013
3822 Actin, alpha skeletal muscle ACTA1 0.0013
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0013
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0013
207 Glutathione synthetase GSS 0.0013
5269 Glutathione synthetase gshB 0.0013
504 Mast/stem cell growth factor receptor KIT 0.0012
509 Thymidine kinase TK 0.0012
570 Thymidine kinase TK 0.0012
2559 Thymidine kinase TK 0.0012
3430 Thymidine kinase tdk 0.0012
3518 Thymidine kinase TK 0.0012
5301 Thymidine kinase tdk 0.0012
5771 Thymidine kinase ORF36 0.0012
7009 Thymidine kinase ORF36 0.0012
1721 Glycogen synthase kinase-3 beta GSK3B 0.0012
5294 Nucleoside diphosphate kinase A NME1 0.0012
5682 Ribonuclease pancreatic RNASE1 0.0011
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.001
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.001
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.001
4773 Deoxycytidine kinase DCK 0.0009
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