DT-Web

DB04027 - D-Arginine


Identification
Name D-Arginine
Accession Number DB04027 (EXPT01113)
Type small molecule
Description An essential amino acid that is physiologically active in the L-form. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 175.2089
Groups experimental
Monoisotopic Weight 175.119500744
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Creatine kinase M-type
Name Creatine kinase M-type
Gene Name CKM
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0152

Predictions


Id Partner name Gene Name Score
92 Creatine kinase B-type CKB 0.077
192 Creatine kinase, ubiquitous mitochondrial CKMT1A 0.0724
456 Creatine kinase, sarcomeric mitochondrial CKMT2 0.0716
414 Sodium- and chloride-dependent creatine transporter 1 SLC6A8 0.0695
624 Guanidinoacetate N-methyltransferase GAMT 0.0535
118 Organic cation/carnitine transporter 2 SLC22A5 0.0268
5288 Shikimate kinase aroK 0.0053
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0053
5293 Shikimate kinase 2 aroL 0.0053
5304 UPF0166 protein TM_0021 TM_0021 0.0053
5287 Signaling protein Not Available 0.0053
5292 Putative partitioning protein TT_C1605 0.0053
5266 Activator of hgdC 0.0053
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0053
3199 Phosphopantetheine adenylyltransferase coaD 0.0053
3543 Phosphopantetheine adenylyltransferase coaD 0.0053
3567 Phosphopantetheine adenylyltransferase coaD 0.0053
5289 Phosphopantetheine adenylyltransferase coaD 0.0053
2874 Nitrogenase iron protein 1 nifH1 0.0053
4346 Polynucleotide kinase pseT 0.0053
5283 D-alanine--D-alanine ligase B ddlB 0.0053
5291 Glycogen synthase 1 glgA1 0.0053
5281 Plasmid segregation protein parM parM 0.0053
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0053
5299 D-alanine--D-alanine ligase ddl 0.0053
6598 D-alanine--D-alanine ligase ddl 0.0053
5276 Chromosomal replication initiator protein dnaA dnaA 0.0053
5259 Transcriptional regulator ntrC1 0.0053
6699 Transcriptional regulator Cgl2612 0.0053
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0053
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0053
5264 DNA replication protein REP 0.0053
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0053
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0053
5315 Chaperone protein htpG htpG 0.0053
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0053
5284 Large T antigen Not Available 0.0053
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0053
5277 Preprotein translocase subunit secA secA 0.0053
5308 Preprotein translocase secA 1 subunit secA1 0.0053
5285 Kinesin heavy chain KIF5B 0.0053
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0053
5261 Phosphoribosylformylglycinamidine synthase purL 0.0053
3426 Glutamine synthetase glnA 0.0044
3987 Glutamine synthetase GLUL 0.0044
3175 Glutamate--cysteine ligase gshA 0.0044
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0044
3470 Hypothetical protein MG245 homolog MPN_348 0.0044
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0044
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0044
2270 Dephospho-CoA kinase coaE 0.0044
4837 Cag-alfa cag-alfa 0.0044
4774 NTPase P4 Not Available 0.0044
4106 Guanylate kinase GUK1 0.0044
4516 Guanylate kinase gmk 0.0044
2284 Adenylate kinase adk 0.0044
2296 Adenylate kinase adk 0.0044
2311 Adenylate kinase adk 0.0044
2312 Adenylate kinase Not Available 0.0044
5646 Galactokinase GALK1 0.0044
413 Amidophosphoribosyltransferase PPAT 0.0044
2515 Amidophosphoribosyltransferase purF 0.0044
3714 Amidophosphoribosyltransferase purF 0.0044
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0044
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0044
5265 FtsH ftsH 0.0044
4839 DNA polymerase III subunit tau dnaX 0.0044
5302 TrwB trwB 0.0044
6277 Heat shock cognate 71 kDa protein HSPA8 0.0044
5189 Trimethylamine dehydrogenase tmd 0.0044
4838 PMS1 protein homolog 2 PMS2 0.0044
2683 Mono-ADP-ribosyltransferase C3 C3 0.0041
2390 Nonsecretory ribonuclease RNASE2 0.004
2922 Glycerol kinase glpK 0.004
5271 Focal adhesion kinase 1 PTK2 0.004
5312 Kinesin-like protein KIF1A KIF1A 0.004
5300 Antigen peptide transporter 1 TAP1 0.0039
340 Apoptotic protease-activating factor 1 APAF1 0.0039
2892 Acetylglutamate kinase argB 0.0037
3550 Acetylglutamate kinase argB 0.0037
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0037
2371 Pantothenate kinase coaA 0.0037
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0037
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0037
1881 Hexokinase-1 HK1 0.0037
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0037
3669 Ribokinase rbsK 0.0037
825 Arsenical pump-driving ATPase ASNA1 0.0037
3435 Arsenical pump-driving ATPase arsA 0.0037
2615 Chemotaxis protein cheA cheA 0.0037
408 Riboflavin kinase RFK 0.0037
2282 Protein recA recA 0.0037
2315 Protein recA recA 0.0037
2332 Protein recA recA 0.0037
5263 Protein recA recA 0.0037
2727 S-adenosylmethionine synthetase metK 0.0035
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0035
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0035
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0035
2334 Dethiobiotin synthetase bioD 0.0034
6555 Dethiobiotin synthetase bioD 0.0034
2697 Uridine-cytidine kinase 2 UCK2 0.0034
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0034
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0034
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0033
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0033
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0033
207 Glutathione synthetase GSS 0.0032
5269 Glutathione synthetase gshB 0.0032
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0032
48 Pyridoxal kinase PDXK 0.0031
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0031
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0031
6395 Myosin-14 MYH14 0.0031
2091 Endoplasmin HSP90B1 0.0031
702 UMP-CMP kinase CMPK1 0.0031
2251 Thymidylate kinase tmk 0.003
2254 Thymidylate kinase DTYMK 0.003
3522 Thymidylate kinase tmk 0.003
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.003
1422 Serine/threonine-protein kinase 6 AURKA 0.003
3379 Kinesin-like protein KIF11 KIF11 0.0029
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0029
3822 Actin, alpha skeletal muscle ACTA1 0.0028
504 Mast/stem cell growth factor receptor KIT 0.0028
509 Thymidine kinase TK 0.0027
570 Thymidine kinase TK 0.0027
2559 Thymidine kinase TK 0.0027
3430 Thymidine kinase tdk 0.0027
3518 Thymidine kinase TK 0.0027
5301 Thymidine kinase tdk 0.0027
5771 Thymidine kinase ORF36 0.0027
7009 Thymidine kinase ORF36 0.0027
5294 Nucleoside diphosphate kinase A NME1 0.0026
1721 Glycogen synthase kinase-3 beta GSK3B 0.0026
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0025
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0025
5682 Ribonuclease pancreatic RNASE1 0.0024
4773 Deoxycytidine kinase DCK 0.0023
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0022
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