DT-Web

DB07460 - 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE


Identification
Name 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE
Accession Number DB07460
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 468.936
Groups experimental
Monoisotopic Weight 468.167666403
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Focal adhesion kinase 1
Name Focal adhesion kinase 1
Gene Name PTK2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3396

Predictions


Id Partner name Gene Name Score
5304 UPF0166 protein TM_0021 TM_0021 0.0067
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0067
5292 Putative partitioning protein TT_C1605 0.0067
3199 Phosphopantetheine adenylyltransferase coaD 0.0067
3543 Phosphopantetheine adenylyltransferase coaD 0.0067
3567 Phosphopantetheine adenylyltransferase coaD 0.0067
5289 Phosphopantetheine adenylyltransferase coaD 0.0067
5293 Shikimate kinase 2 aroL 0.0067
5287 Signaling protein Not Available 0.0067
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0067
5283 D-alanine--D-alanine ligase B ddlB 0.0067
5266 Activator of hgdC 0.0067
2874 Nitrogenase iron protein 1 nifH1 0.0067
5299 D-alanine--D-alanine ligase ddl 0.0067
6598 D-alanine--D-alanine ligase ddl 0.0067
4346 Polynucleotide kinase pseT 0.0067
5288 Shikimate kinase aroK 0.0067
5284 Large T antigen Not Available 0.0067
5281 Plasmid segregation protein parM parM 0.0067
5276 Chromosomal replication initiator protein dnaA dnaA 0.0067
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0067
5259 Transcriptional regulator ntrC1 0.0067
6699 Transcriptional regulator Cgl2612 0.0067
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0067
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0067
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0067
5291 Glycogen synthase 1 glgA1 0.0067
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0067
5264 DNA replication protein REP 0.0067
5277 Preprotein translocase subunit secA secA 0.0067
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0067
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0067
5315 Chaperone protein htpG htpG 0.0067
5308 Preprotein translocase secA 1 subunit secA1 0.0067
5285 Kinesin heavy chain KIF5B 0.0067
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0067
5261 Phosphoribosylformylglycinamidine synthase purL 0.0067
4106 Guanylate kinase GUK1 0.0058
4516 Guanylate kinase gmk 0.0058
4837 Cag-alfa cag-alfa 0.0058
3470 Hypothetical protein MG245 homolog MPN_348 0.0058
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0058
2270 Dephospho-CoA kinase coaE 0.0058
2284 Adenylate kinase adk 0.0058
2296 Adenylate kinase adk 0.0058
2311 Adenylate kinase adk 0.0058
2312 Adenylate kinase Not Available 0.0058
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0058
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0058
3426 Glutamine synthetase glnA 0.0058
3987 Glutamine synthetase GLUL 0.0058
4774 NTPase P4 Not Available 0.0058
3175 Glutamate--cysteine ligase gshA 0.0058
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0058
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0058
5646 Galactokinase GALK1 0.0058
6277 Heat shock cognate 71 kDa protein HSPA8 0.0058
413 Amidophosphoribosyltransferase PPAT 0.0058
2515 Amidophosphoribosyltransferase purF 0.0058
3714 Amidophosphoribosyltransferase purF 0.0058
5302 TrwB trwB 0.0058
4838 PMS1 protein homolog 2 PMS2 0.0058
5265 FtsH ftsH 0.0058
4839 DNA polymerase III subunit tau dnaX 0.0058
5189 Trimethylamine dehydrogenase tmd 0.0058
2390 Nonsecretory ribonuclease RNASE2 0.0054
2683 Mono-ADP-ribosyltransferase C3 C3 0.0054
2922 Glycerol kinase glpK 0.0054
5312 Kinesin-like protein KIF1A KIF1A 0.0053
5300 Antigen peptide transporter 1 TAP1 0.0051
340 Apoptotic protease-activating factor 1 APAF1 0.0051
3669 Ribokinase rbsK 0.0051
2371 Pantothenate kinase coaA 0.0051
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0051
2892 Acetylglutamate kinase argB 0.0051
3550 Acetylglutamate kinase argB 0.0051
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0051
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0051
825 Arsenical pump-driving ATPase ASNA1 0.0051
3435 Arsenical pump-driving ATPase arsA 0.0051
1881 Hexokinase-1 HK1 0.0051
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0051
2615 Chemotaxis protein cheA cheA 0.0051
408 Riboflavin kinase RFK 0.0049
2282 Protein recA recA 0.0049
2315 Protein recA recA 0.0049
2332 Protein recA recA 0.0049
5263 Protein recA recA 0.0049
2727 S-adenosylmethionine synthetase metK 0.0048
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0048
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0048
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0047
788 Creatine kinase M-type CKM 0.0047
2334 Dethiobiotin synthetase bioD 0.0047
6555 Dethiobiotin synthetase bioD 0.0047
2697 Uridine-cytidine kinase 2 UCK2 0.0047
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0047
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0045
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0045
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0045
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0044
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0043
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0043
6395 Myosin-14 MYH14 0.0043
48 Pyridoxal kinase PDXK 0.0043
2091 Endoplasmin HSP90B1 0.0043
702 UMP-CMP kinase CMPK1 0.0042
2251 Thymidylate kinase tmk 0.0042
2254 Thymidylate kinase DTYMK 0.0042
3522 Thymidylate kinase tmk 0.0042
1422 Serine/threonine-protein kinase 6 AURKA 0.0041
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0041
3379 Kinesin-like protein KIF11 KIF11 0.0041
207 Glutathione synthetase GSS 0.004
5269 Glutathione synthetase gshB 0.004
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.004
3456 Heat shock protein HSP 90-beta HSP90AB1 0.004
3822 Actin, alpha skeletal muscle ACTA1 0.0039
504 Mast/stem cell growth factor receptor KIT 0.0038
509 Thymidine kinase TK 0.0037
570 Thymidine kinase TK 0.0037
2559 Thymidine kinase TK 0.0037
3430 Thymidine kinase tdk 0.0037
3518 Thymidine kinase TK 0.0037
5301 Thymidine kinase tdk 0.0037
5771 Thymidine kinase ORF36 0.0037
7009 Thymidine kinase ORF36 0.0037
5294 Nucleoside diphosphate kinase A NME1 0.0037
1721 Glycogen synthase kinase-3 beta GSK3B 0.0036
5682 Ribonuclease pancreatic RNASE1 0.0034
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0033
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0033
4773 Deoxycytidine kinase DCK 0.0032
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0031
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