DT-Web

DB08465 - 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE


Identification
Name 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE
Accession Number DB08465
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 397.807
Groups experimental
Monoisotopic Weight 397.092829706
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Heat shock protein HSP 90-beta
Name Heat shock protein HSP 90-beta
Gene Name HSP90AB1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4872
Endoplasmin
Name Endoplasmin
Gene Name HSP90B1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1879

Predictions


Id Partner name Gene Name Score
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.2477
6840 Virulence sensor histidine kinase phoQ phoQ 0.105
6839 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial PDK3 0.0914
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0756
512 DNA-directed RNA polymerase alpha chain rpoA 0.0326
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0326
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0278
284 DNA-directed RNA polymerase beta chain rpoB 0.0255
5773 DNA-directed RNA polymerase beta chain rpoB 0.0255
4200 Cytochrome P450 1A2 CYP1A2 0.0108
4512 Cytochrome P450 3A4 CYP3A4 0.0094
5315 Chaperone protein htpG htpG 0.0051
5287 Signaling protein Not Available 0.0051
5304 UPF0166 protein TM_0021 TM_0021 0.0051
5288 Shikimate kinase aroK 0.0051
5293 Shikimate kinase 2 aroL 0.0051
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0051
5276 Chromosomal replication initiator protein dnaA dnaA 0.0051
3199 Phosphopantetheine adenylyltransferase coaD 0.0051
3543 Phosphopantetheine adenylyltransferase coaD 0.0051
3567 Phosphopantetheine adenylyltransferase coaD 0.0051
5289 Phosphopantetheine adenylyltransferase coaD 0.0051
4346 Polynucleotide kinase pseT 0.0051
5281 Plasmid segregation protein parM parM 0.0051
5283 D-alanine--D-alanine ligase B ddlB 0.0051
5259 Transcriptional regulator ntrC1 0.0051
6699 Transcriptional regulator Cgl2612 0.0051
5266 Activator of hgdC 0.0051
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0051
2874 Nitrogenase iron protein 1 nifH1 0.0051
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0051
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0051
5292 Putative partitioning protein TT_C1605 0.0051
5264 DNA replication protein REP 0.0051
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0051
5291 Glycogen synthase 1 glgA1 0.0051
5299 D-alanine--D-alanine ligase ddl 0.0051
6598 D-alanine--D-alanine ligase ddl 0.0051
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0051
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0051
5284 Large T antigen Not Available 0.0051
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0051
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0051
5277 Preprotein translocase subunit secA secA 0.0051
5285 Kinesin heavy chain KIF5B 0.0051
5308 Preprotein translocase secA 1 subunit secA1 0.0051
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0051
5261 Phosphoribosylformylglycinamidine synthase purL 0.0051
3470 Hypothetical protein MG245 homolog MPN_348 0.0044
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0044
6277 Heat shock cognate 71 kDa protein HSPA8 0.0044
4106 Guanylate kinase GUK1 0.0044
4516 Guanylate kinase gmk 0.0044
2270 Dephospho-CoA kinase coaE 0.0044
5189 Trimethylamine dehydrogenase tmd 0.0044
2284 Adenylate kinase adk 0.0044
2296 Adenylate kinase adk 0.0044
2311 Adenylate kinase adk 0.0044
2312 Adenylate kinase Not Available 0.0044
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0044
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0044
3175 Glutamate--cysteine ligase gshA 0.0044
5302 TrwB trwB 0.0044
4837 Cag-alfa cag-alfa 0.0044
4774 NTPase P4 Not Available 0.0044
5265 FtsH ftsH 0.0044
3426 Glutamine synthetase glnA 0.0044
3987 Glutamine synthetase GLUL 0.0044
5646 Galactokinase GALK1 0.0044
413 Amidophosphoribosyltransferase PPAT 0.0044
2515 Amidophosphoribosyltransferase purF 0.0044
3714 Amidophosphoribosyltransferase purF 0.0044
4839 DNA polymerase III subunit tau dnaX 0.0044
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0044
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0044
4838 PMS1 protein homolog 2 PMS2 0.0044
2683 Mono-ADP-ribosyltransferase C3 C3 0.0041
5271 Focal adhesion kinase 1 PTK2 0.004
2390 Nonsecretory ribonuclease RNASE2 0.004
2922 Glycerol kinase glpK 0.004
5312 Kinesin-like protein KIF1A KIF1A 0.004
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0038
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0038
2371 Pantothenate kinase coaA 0.0038
2892 Acetylglutamate kinase argB 0.0038
3550 Acetylglutamate kinase argB 0.0038
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0038
2615 Chemotaxis protein cheA cheA 0.0038
3669 Ribokinase rbsK 0.0038
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0038
825 Arsenical pump-driving ATPase ASNA1 0.0038
3435 Arsenical pump-driving ATPase arsA 0.0038
1881 Hexokinase-1 HK1 0.0038
340 Apoptotic protease-activating factor 1 APAF1 0.0037
5300 Antigen peptide transporter 1 TAP1 0.0037
408 Riboflavin kinase RFK 0.0036
2282 Protein recA recA 0.0036
2315 Protein recA recA 0.0036
2332 Protein recA recA 0.0036
5263 Protein recA recA 0.0036
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0036
2727 S-adenosylmethionine synthetase metK 0.0036
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0035
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0035
2334 Dethiobiotin synthetase bioD 0.0035
6555 Dethiobiotin synthetase bioD 0.0035
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0035
2697 Uridine-cytidine kinase 2 UCK2 0.0035
788 Creatine kinase M-type CKM 0.0035
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0034
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0034
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0034
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0033
6395 Myosin-14 MYH14 0.0032
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0032
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0032
48 Pyridoxal kinase PDXK 0.0031
2251 Thymidylate kinase tmk 0.0031
2254 Thymidylate kinase DTYMK 0.0031
3522 Thymidylate kinase tmk 0.0031
702 UMP-CMP kinase CMPK1 0.0031
1422 Serine/threonine-protein kinase 6 AURKA 0.0031
3379 Kinesin-like protein KIF11 KIF11 0.003
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0029
3822 Actin, alpha skeletal muscle ACTA1 0.0029
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0029
207 Glutathione synthetase GSS 0.0029
5269 Glutathione synthetase gshB 0.0029
504 Mast/stem cell growth factor receptor KIT 0.0027
509 Thymidine kinase TK 0.0027
570 Thymidine kinase TK 0.0027
2559 Thymidine kinase TK 0.0027
3430 Thymidine kinase tdk 0.0027
3518 Thymidine kinase TK 0.0027
5301 Thymidine kinase tdk 0.0027
5771 Thymidine kinase ORF36 0.0027
7009 Thymidine kinase ORF36 0.0027
5294 Nucleoside diphosphate kinase A NME1 0.0027
1721 Glycogen synthase kinase-3 beta GSK3B 0.0027
5682 Ribonuclease pancreatic RNASE1 0.0025
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0024
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0024
4773 Deoxycytidine kinase DCK 0.0022
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