DT-Web

DB02236 - Glycinamide Ribonucleotide


Identification
Name Glycinamide Ribonucleotide
Accession Number DB02236 (EXPT01547)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 284.1605
Groups experimental
Monoisotopic Weight 284.040951914
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Phosphoribosylglycinamide formyltransferase 2
Name Phosphoribosylglycinamide formyltransferase 2
Gene Name purT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.578
Phosphoribosylglycinamide formyltransferase
Name Phosphoribosylglycinamide formyltransferase
Gene Name purN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.933
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase
Name Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase
Gene Name GART
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1169

Predictions


Id Partner name Gene Name Score
3514 Granulysin GNLY 0.1356
3500 Putative family 31 glucosidase yicI yicI 0.1026
2878 Probable serine/threonine-protein kinase pknB pknB 0.0714
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0641
4773 Deoxycytidine kinase DCK 0.0513
2897 ATP-dependent DNA helicase recQ recQ 0.0508
365 Dihydrofolate reductase DHFR 0.0499
2381 Dihydrofolate reductase DFR1 0.0499
2833 Dihydrofolate reductase Not Available 0.0499
2931 Dihydrofolate reductase folA 0.0499
3544 Dihydrofolate reductase folA 0.0499
3682 Dihydrofolate reductase folA 0.0499
6642 Dihydrofolate reductase folA 0.0499
6756 Dihydrofolate reductase dfrA 0.0499
24 Thymidylate synthase TMP1 0.0498
359 Thymidylate synthase TYMS 0.0498
2626 Thymidylate synthase thyA 0.0498
2729 Thymidylate synthase thyA 0.0498
5352 Thymidylate synthase THYA 0.0498
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0491
4837 Cag-alfa cag-alfa 0.0475
4839 DNA polymerase III subunit tau dnaX 0.0475
4838 PMS1 protein homolog 2 PMS2 0.0475
1750 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 0.0368
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0353
5312 Kinesin-like protein KIF1A KIF1A 0.0352
2615 Chemotaxis protein cheA cheA 0.0333
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0322
2621 Thermoresistant gluconokinase gntK 0.0272
5466 Putative sugar kinase STM4066 0.0272
4517 Probable butyrate kinase 2 buk2 0.0272
3669 Ribokinase rbsK 0.0266
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0254
2717 Folylpolyglutamate synthase fgs 0.0226
48 Pyridoxal kinase PDXK 0.0219
36 Insulin receptor INSR 0.0193
3390 Aminoglycoside 3'-phosphotransferase aphA 0.011
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.011
5646 Galactokinase GALK1 0.011
5265 FtsH ftsH 0.011
5302 TrwB trwB 0.011
2371 Pantothenate kinase coaA 0.0096
2892 Acetylglutamate kinase argB 0.0096
3550 Acetylglutamate kinase argB 0.0096
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0096
825 Arsenical pump-driving ATPase ASNA1 0.0096
3435 Arsenical pump-driving ATPase arsA 0.0096
1881 Hexokinase-1 HK1 0.0096
2727 S-adenosylmethionine synthetase metK 0.0092
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0089
5641 Rod shape-determining protein MreB TM_0588 0.0088
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0088
5645 DNA topoisomerase 4 subunit B parE 0.0088
6227 DNA topoisomerase 4 subunit B parE 0.0088
3794 Osmolarity sensor protein envZ envZ 0.0088
5644 Sensor protein phoQ phoQ 0.0088
5643 General secretion pathway protein E epsE 0.0088
5649 Potassium-transporting ATPase B chain kdpB 0.0088
5642 Chaperone clpB clpB 0.0088
2251 Thymidylate kinase tmk 0.008
2254 Thymidylate kinase DTYMK 0.008
3522 Thymidylate kinase tmk 0.008
4751 Mitogen-activated protein kinase 12 MAPK12 0.0077
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0077
2397 Dihydroxyacetone kinase dhaK 0.0077
740 Argininosuccinate synthase ASS1 0.0077
865 Argininosuccinate synthase ASS1 0.0077
2680 Argininosuccinate synthase argG 0.0077
3194 Argininosuccinate synthase argG 0.0077
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0077
2852 DNA mismatch repair protein mutL mutL 0.0077
3822 Actin, alpha skeletal muscle ACTA1 0.0075
207 Glutathione synthetase GSS 0.0074
5269 Glutathione synthetase gshB 0.0074
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0073
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0071
3231 Death-associated protein kinase 1 DAPK1 0.0071
1721 Glycogen synthase kinase-3 beta GSK3B 0.0068
936 Ephrin type-A receptor 2 EPHA2 0.0063
887 DNA gyrase subunit B gyrB 0.0063
4150 DNA gyrase subunit B gyrB 0.0063
6225 DNA gyrase subunit B gyrB 0.0063
958 Insulin-like growth factor 1 receptor IGF1R 0.0057
4192 DNA topoisomerase 2-beta TOP2B 0.0052
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0052
1836 Mitogen-activated protein kinase 10 MAPK10 0.005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0048
2236 Casein kinase II subunit alpha CSNK2A1 0.0047
3199 Phosphopantetheine adenylyltransferase coaD 0.0038
3543 Phosphopantetheine adenylyltransferase coaD 0.0038
3567 Phosphopantetheine adenylyltransferase coaD 0.0038
5289 Phosphopantetheine adenylyltransferase coaD 0.0038
5293 Shikimate kinase 2 aroL 0.0038
5288 Shikimate kinase aroK 0.0038
5304 UPF0166 protein TM_0021 TM_0021 0.0038
2874 Nitrogenase iron protein 1 nifH1 0.0038
4346 Polynucleotide kinase pseT 0.0038
5283 D-alanine--D-alanine ligase B ddlB 0.0038
5287 Signaling protein Not Available 0.0038
5292 Putative partitioning protein TT_C1605 0.0038
5266 Activator of hgdC 0.0038
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0038
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0038
5281 Plasmid segregation protein parM parM 0.0038
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0038
5299 D-alanine--D-alanine ligase ddl 0.0038
6598 D-alanine--D-alanine ligase ddl 0.0038
5276 Chromosomal replication initiator protein dnaA dnaA 0.0038
5259 Transcriptional regulator ntrC1 0.0038
6699 Transcriptional regulator Cgl2612 0.0038
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5291 Glycogen synthase 1 glgA1 0.0038
5264 DNA replication protein REP 0.0038
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0038
5308 Preprotein translocase secA 1 subunit secA1 0.0038
5315 Chaperone protein htpG htpG 0.0038
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0038
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0038
5277 Preprotein translocase subunit secA secA 0.0038
5284 Large T antigen Not Available 0.0038
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0038
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0038
5261 Phosphoribosylformylglycinamidine synthase purL 0.0038
5285 Kinesin heavy chain KIF5B 0.0038
4106 Guanylate kinase GUK1 0.0033
4516 Guanylate kinase gmk 0.0033
2270 Dephospho-CoA kinase coaE 0.0033
2284 Adenylate kinase adk 0.0033
2296 Adenylate kinase adk 0.0033
2311 Adenylate kinase adk 0.0033
2312 Adenylate kinase Not Available 0.0033
3470 Hypothetical protein MG245 homolog MPN_348 0.0033
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0033
4774 NTPase P4 Not Available 0.0033
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0033
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0033
6277 Heat shock cognate 71 kDa protein HSPA8 0.0033
3426 Glutamine synthetase glnA 0.0033
3987 Glutamine synthetase GLUL 0.0033
3175 Glutamate--cysteine ligase gshA 0.0033
413 Amidophosphoribosyltransferase PPAT 0.0033
2515 Amidophosphoribosyltransferase purF 0.0033
3714 Amidophosphoribosyltransferase purF 0.0033
5189 Trimethylamine dehydrogenase tmd 0.0033
2390 Nonsecretory ribonuclease RNASE2 0.0031
2683 Mono-ADP-ribosyltransferase C3 C3 0.0031
2922 Glycerol kinase glpK 0.0031
5271 Focal adhesion kinase 1 PTK2 0.0031
340 Apoptotic protease-activating factor 1 APAF1 0.0031
2282 Protein recA recA 0.0029
2315 Protein recA recA 0.0029
2332 Protein recA recA 0.0029
5263 Protein recA recA 0.0029
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0029
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0029
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0029
408 Riboflavin kinase RFK 0.0028
5300 Antigen peptide transporter 1 TAP1 0.0028
2334 Dethiobiotin synthetase bioD 0.0027
6555 Dethiobiotin synthetase bioD 0.0027
2697 Uridine-cytidine kinase 2 UCK2 0.0027
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0027
788 Creatine kinase M-type CKM 0.0027
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0025
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0025
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0025
6395 Myosin-14 MYH14 0.0025
2091 Endoplasmin HSP90B1 0.0024
702 UMP-CMP kinase CMPK1 0.0024
1422 Serine/threonine-protein kinase 6 AURKA 0.0024
3379 Kinesin-like protein KIF11 KIF11 0.0023
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0023
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0023
509 Thymidine kinase TK 0.0021
570 Thymidine kinase TK 0.0021
2559 Thymidine kinase TK 0.0021
3430 Thymidine kinase tdk 0.0021
3518 Thymidine kinase TK 0.0021
5301 Thymidine kinase tdk 0.0021
5771 Thymidine kinase ORF36 0.0021
7009 Thymidine kinase ORF36 0.0021
504 Mast/stem cell growth factor receptor KIT 0.0021
5294 Nucleoside diphosphate kinase A NME1 0.0021
5682 Ribonuclease pancreatic RNASE1 0.0019
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0019
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0019
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0018
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