DT-Web

DB04930 - Permethrin


Identification
Name Permethrin
Accession Number DB04930
Type small molecule
Description A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 391.288
Groups approved
Monoisotopic Weight 390.07894992
Pharmacology
Indication For the treatment of infestation with Sarcoptes scabiei (scabies).
Mechanism of action Permethrin acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization and paralysis of the pests are the consequences of this disturbance.
Absorption Poorly absorbed through the skin.
Protein binding Not Available
Biotransformation Rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in the urine.
Route of elimination Permethrin is rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in the urine.
Toxicity Oral, rat LD50: 430 - 4000 mg/kg; skin, rabbit LD50: 2000 mg/kg.
Affected organisms
  • Scabies (Sarcoptes scabei) and other insects
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Sodium channel protein type 1 subunit alpha
Name Sodium channel protein type 1 subunit alpha
Gene Name SCN1A
Pharmacological action yes
Actions inhibitor
References
  • Cao Z, Shafer TJ, Murray TF: Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons. J Pharmacol Exp Ther. 2011 Jan;336(1):197-205. Epub 2010 Sep 29. - Pubmed
  • Liu N, Xu Q, Li T, He L, Zhang L: Permethrin resistance and target site insensitivity in the mosquito Culex quinquefasciatus in Alabama. J Med Entomol. 2009 Nov;46(6):1424-9. - Pubmed
  • Breckenridge CB, Holden L, Sturgess N, Weiner M, Sheets L, Sargent D, Soderlund DM, Choi JS, Symington S, Clark JM, Burr S, Ray D: Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides. Neurotoxicology. 2009 Nov;30 Suppl 1:S17-31. Epub 2009 Sep 18. - Pubmed
  • Chang C, Shen WK, Wang TT, Lin YH, Hsu EL, Dai SM: A novel amino acid substitution in a voltage-gated sodium channel is associated with knockdown resistance to permethrin in Aedes aegypti. Insect Biochem Mol Biol. 2009 Apr;39(4):272-8. Epub 2009 Jan 10. - Pubmed
  • McMahon C, Krober T, Guerin PM: In vitro assays for repellents and deterrents for ticks: differing effects of products when tested with attractant or arrestment stimuli. Med Vet Entomol. 2003 Dec;17(4):370-8. - Pubmed
DTHybrid score 0.5067

Enzymes


Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions substrate,inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.229
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3468

Predictions


Id Partner name Gene Name Score
4119 Cytochrome P450 2D6 CYP2D6 0.1057
6016 Cytochrome P450 2C19 CYP2C19 0.1049
4757 Cytochrome P450 2C9 CYP2C9 0.0981
1588 Multidrug resistance protein 1 ABCB1 0.0914
4200 Cytochrome P450 1A2 CYP1A2 0.0812
4118 Cytochrome P450 3A5 CYP3A5 0.0786
4924 Cytochrome P450 2C8 CYP2C8 0.0761
6107 Cytochrome P450 3A7 CYP3A7 0.0565
6013 Cytochrome P450 2E1 CYP2E1 0.0561
5718 Cytochrome P450 2A6 CYP2A6 0.0389
587 Serum albumin ALB 0.0369
6024 Cytochrome P450 1A1 CYP1A1 0.0317
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0307
6106 Cytochrome P450 2C18 CYP2C18 0.0275
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0257
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0244
592 Carbonic anhydrase 4 CA4 0.0237
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0232
492 Histamine H1 receptor HRH1 0.023
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0219
3811 Cytochrome P450 19A1 CYP19A1 0.0215
20 Prostaglandin G/H synthase 1 PTGS1 0.0188
824 Sodium-dependent serotonin transporter SLC6A4 0.0187
357 Carbonic anhydrase 2 CA2 0.0184
556 Alpha-1A adrenergic receptor ADRA1A 0.0184
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0181
871 Glucocorticoid receptor NR3C1 0.0168
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0167
318 Alpha-2A adrenergic receptor ADRA2A 0.0162
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0156
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0156
862 Multidrug resistance-associated protein 1 ABCC1 0.0151
136 Estrogen receptor ESR1 0.015
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.014
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.014
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0139
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0139
731 HIV-1 protease HIV-1 protease 0.0138
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0136
502 5-hydroxytryptamine 2A receptor HTR2A 0.0135
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.013
847 Mu-type opioid receptor OPRM1 0.013
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0126
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0125
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0123
632 Alpha-1B adrenergic receptor ADRA1B 0.0121
831 D(2) dopamine receptor DRD2 0.012
713 Sodium-dependent dopamine transporter SLC6A3 0.0119
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0118
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0117
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0117
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0116
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0116
260 Cytochrome P450 51 ERG11 0.0114
761 Cytochrome P450 51 ERG11 0.0114
3163 Cytochrome P450 51 cyp51 0.0114
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0113
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0113
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0112
789 Alpha-1D adrenergic receptor ADRA1D 0.0111
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0111
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0111
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0111
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0109
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0108
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0108
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0108
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0108
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0108
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0107
233 Potassium channel subfamily K member 2 KCNK2 0.0107
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0106
6145 Solute carrier family 22 member 1 SLC22A1 0.0103
467 Delta-type opioid receptor OPRD1 0.0101
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.01
1898 Cytochrome P450 1B1 CYP1B1 0.0099
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0099
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0099
468 Cytochrome P450 4A11 CYP4A11 0.0099
776 Bile salt export pump ABCB11 0.0097
3923 Cholinesterase BCHE 0.0096
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0096
122 P2Y purinoceptor 12 P2RY12 0.0095
629 Alpha-2B adrenergic receptor ADRA2B 0.0094
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0094
6144 Solute carrier family 22 member 2 SLC22A2 0.0093
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0093
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0092
378 Alpha-2C adrenergic receptor ADRA2C 0.0091
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0091
818 50S ribosomal protein L10 rplJ 0.009
1729 Solute carrier family 22 member 6 SLC22A6 0.009
6020 Aldehyde oxidase AOX1 0.009
696 Kappa-type opioid receptor OPRK1 0.0089
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0089
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0089
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0088
465 Calmodulin CALM1 0.0087
590 5-hydroxytryptamine 2C receptor HTR2C 0.0087
193 Beta-1 adrenergic receptor ADRB1 0.0085
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0084
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0082
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0082
3941 Amine oxidase [flavin-containing] A MAOA 0.0081
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.008
232 Corticosteroid-binding globulin SERPINA6 0.008
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0079
320 5-hydroxytryptamine 1A receptor HTR1A 0.0079
290 Prostaglandin G/H synthase 2 PTGS2 0.0078
118 Organic cation/carnitine transporter 2 SLC22A5 0.0077
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0077
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0076
341 5-hydroxytryptamine 3 receptor HTR3A 0.0076
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0076
6142 Solute carrier family 22 member 8 SLC22A8 0.0076
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0075
174 Sigma 1-type opioid receptor SIGMAR1 0.0074
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0074
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0073
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0073
3939 Amine oxidase [flavin-containing] B MAOB 0.0072
6133 Sodium channel subunit beta-2 SCN2B 0.0071
6135 Sodium channel subunit beta-4 SCN4B 0.0071
6134 Sodium channel subunit beta-3 SCN3B 0.0071
6132 Sodium channel subunit beta-1 SCN1B 0.0071
6127 Carbonic anhydrase-related protein CA8 0.0071
6128 Carbonic anhydrase-related protein 10 CA10 0.0071
6129 Carbonic anhydrase-related protein 11 CA11 0.0071
4120 NADPH--cytochrome P450 reductase POR 0.0068
295 Carbonic anhydrase 1 CA1 0.0067
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0066
23 D(1A) dopamine receptor DRD1 0.0066
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0066
6131 Carbonic anhydrase 14 CA14 0.0065
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0064
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0064
705 Glutamate receptor 1 GRIA1 0.0064
6130 Carbonic anhydrase 13 CA13 0.0063
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0063
482 Glycine receptor subunit alpha-1 GLRA1 0.0063
6147 Solute carrier family 22 member 3 SLC22A3 0.0062
614 Progesterone receptor PGR 0.0062
6122 Carbonic anhydrase 3 CA3 0.0062
146 Androgen receptor AR 0.0061
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.006
2164 Multidrug resistance-associated protein 4 ABCC4 0.006
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0059
6031 Cytochrome P450 3A43 CYP3A43 0.0059
6126 Carbonic anhydrase 7 CA7 0.0057
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0056
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0056
1656 CYP2B protein CYP2B 0.0055
6220 Aryl hydrocarbon receptor AHR 0.0055
29 Tubulin beta-1 chain TUBB1 0.0055
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0054
833 Organic cation/carnitine transporter 1 SLC22A4 0.0054
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0054
811 Translocator protein TSPO 0.0053
537 ATP synthase delta chain, mitochondrial ATP5D 0.0053
638 D(3) dopamine receptor DRD3 0.0053
756 Sex hormone-binding globulin SHBG 0.0052
766 Beta-2 adrenergic receptor ADRB2 0.0052
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0052
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0052
504 Mast/stem cell growth factor receptor KIT 0.0051
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0051
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.005
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.005
4604 Liver carboxylesterase 1 CES1 0.005
80 Peroxisome proliferator-activated receptor alpha PPARA 0.005
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.005
4205 Carbonic anhydrase 9 CA9 0.0049
3007 Carbonic anhydrase 12 CA12 0.0049
6182 Cytochrome P450 2J2 CYP2J2 0.0049
161 Tubulin beta chain TUBB 0.0048
312 Tubulin beta chain TUB2 0.0048
6143 Solute carrier family 22 member 7 SLC22A7 0.0048
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0047
856 Vitamin D3 receptor VDR 0.0046
869 Estrogen receptor beta ESR2 0.0046
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0045
952 Dipeptidyl peptidase 4 DPP4 0.0045
6137 Multidrug resistance-associated protein 6 ABCC6 0.0045
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0045
716 5-hydroxytryptamine 7 receptor HTR7 0.0044
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0043
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0043
885 5-hydroxytryptamine 1B receptor HTR1B 0.0042
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0042
817 DNA topoisomerase 2-alpha TOP2A 0.0042
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6136 Multidrug resistance-associated protein 5 ABCC5 0.004
725 5-hydroxytryptamine 1D receptor HTR1D 0.004
1010 Cytochrome P450 51A1 CYP51A1 0.0039
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
3932 Glutathione S-transferase A2 GSTA2 0.0039
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0038
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
891 Dihydropteroate synthase folP 0.0038
5359 Dihydropteroate synthase folP 0.0038
7175 Dihydropteroate synthase sulI 0.0038
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0038
407 Vascular endothelial growth factor receptor 2 KDR 0.0037
427 Substance-P receptor TACR1 0.0036
68 Cannabinoid receptor 1 CNR1 0.0036
284 DNA-directed RNA polymerase beta chain rpoB 0.0035
5773 DNA-directed RNA polymerase beta chain rpoB 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
3947 Xanthine dehydrogenase/oxidase XDH 0.0035
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0035
939 50S ribosomal protein L3 rplC 0.0035
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0034
6138 Multidrug resistance protein 3 ABCB4 0.0034
6148 Multidrug resistance-associated protein 7 ABCC10 0.0034
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0034
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0034
6014 Cytochrome P450 2A13 CYP2A13 0.0034
26 Vascular endothelial growth factor receptor 3 FLT4 0.0033
844 Epidermal growth factor receptor EGFR 0.0033
474 Acetylcholinesterase ACHE 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0033
814 Ryanodine receptor 1 RYR1 0.0033
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0032
124 Histamine H2 receptor HRH2 0.0032
32 Vascular endothelial growth factor receptor 1 FLT1 0.0032
921 Glutamate receptor 2 GRIA2 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
432 D(4) dopamine receptor DRD4 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.003
228 Beta platelet-derived growth factor receptor PDGFRB 0.003
6043 Putative G-protein coupled receptor 44 GPR44 0.003
581 Cytochrome P450 2R1 CYP2R1 0.003
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0029
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0029
1024 Solute carrier family 22 member 11 SLC22A11 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
723 Cytosolic phospholipase A2 PLA2G4A 0.0027
436 5-hydroxytryptamine 2B receptor HTR2B 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0027
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0026
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0026
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0026
49 Endothelin B receptor EDNRB 0.0026
563 Thyroid peroxidase TPO 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
578 Endothelin-1 receptor EDNRA 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
1483 Membrane copper amine oxidase AOC3 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
1757 Myeloperoxidase MPO 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
373 Transthyretin TTR 0.0023
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0023
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0023
777 Tumor necrosis factor TNF 0.0023
70 Type-1 angiotensin II receptor AGTR1 0.0023
1262 Corticotropin-lipotropin POMC 0.0023
84 Nuclear receptor 0B1 NR0B1 0.0022
737 Mineralocorticoid receptor NR3C2 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0022
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0021
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0021
275 Arachidonate 5-lipoxygenase ALOX5 0.0021
380 Cytochrome P450 17A1 CYP17A1 0.0021
163 D(1B) dopamine receptor DRD5 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
2539 Tubulin alpha-1 chain TUBA4A 0.0021
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0021
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0021
94 5-hydroxytryptamine 4 receptor HTR4 0.002
780 Retinoic acid receptor RXR-gamma RXRG 0.002
1618 High affinity nerve growth factor receptor NTRK1 0.002
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.002
6085 Fatty acid-binding protein, intestinal FABP2 0.002
6432 Transporter snf 0.002
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
633 Penicillin-binding proteins 1A/1B pbpA 0.0019
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0019
7 Nitric oxide synthase, inducible NOS2 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0019
6141 Sodium/bile acid cotransporter SLC10A1 0.0019
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0019
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0019
88 Retinoic acid receptor RXR-beta RXRB 0.0019
5787 Angiopoietin-1 receptor TEK 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
1992 Vitamin D-binding protein GC 0.0019
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
6102 Arylamine N-acetyltransferase 2 NAT2 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0018
319 Opioid receptor, sigma 1 OPRS1 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
683 Potassium transporter GK0582 0.0018
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0018
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0018
904 Glutathione S-transferase P GSTP1 0.0017
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
1630 Integrin beta-2 ITGB2 0.0017
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0017
1256 5-hydroxytryptamine 6 receptor HTR6 0.0017
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0017
1050 Bile salt sulfotransferase SULT2A1 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
165 FL cytokine receptor FLT3 0.0017
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0017
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
1852 Microtubule-associated protein 2 MAP2 0.0016
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0016
173 Toll-like receptor 7 TLR7 0.0016
3233 Bile acid receptor NR1H4 0.0015
251 Alcohol dehydrogenase 1A ADH1A 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
1629 Transcription factor AP-1 JUN 0.0015
3937 Fatty-acid amide hydrolase FAAH 0.0015
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
1541 Metalloproteinase mmp20 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
444 Alcohol dehydrogenase 1B ADH1B 0.0014
469 Annexin A1 ANXA1 0.0014
896 Glutathione S-transferase Mu 1 GSTM1 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
936 Ephrin type-A receptor 2 EPHA2 0.0013
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0013
3809 Estrogen-related receptor gamma ESRRG 0.0013
5798 Mitogen-activated protein kinase 11 MAPK11 0.0013
4122 Histone deacetylase 2 HDAC2 0.0013
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0013
291 Nitric-oxide synthase, endothelial NOS3 0.0013
1192 Sulfotransferase 1A1 SULT1A1 0.0013
569 Retinal dehydrogenase 2 ALDH1A2 0.0013
267 Plasminogen activator inhibitor 1 SERPINE1 0.0013
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0013
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
823 Fibroblast growth factor receptor 2 FGFR2 0.0012
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0012
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0012
16 Adenosine A1 receptor ADORA1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
738 Monocarboxylate transporter 1 SLC16A1 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
571 Melatonin receptor type 1A MTNR1A 0.0012
362 Melatonin receptor type 1B MTNR1B 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
517 Alcohol dehydrogenase 1C ADH1C 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
1295 Fatty acid synthase FASN 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0012
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0012
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0012
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0012
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0012
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0012
6221 Steroid hormone receptor ERR1 ESRRA 0.0012
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0012
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0012
1178 Adenosine A2a receptor ADORA2A 0.0011
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0011
605 Fumarate reductase flavoprotein subunit frdA 0.0011
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0011
3673 Fumarate reductase flavoprotein subunit fccA 0.0011
4912 Fumarate reductase flavoprotein subunit ifcA 0.0011
6549 Fumarate reductase flavoprotein subunit frdA 0.0011
239 Coagulation factor X F10 0.0011
5934 Cytochrome P450 26A1 CYP26A1 0.0011
528 5-hydroxytryptamine 1E receptor HTR1E 0.0011
365 Dihydrofolate reductase DHFR 0.0011
2381 Dihydrofolate reductase DFR1 0.0011
2833 Dihydrofolate reductase Not Available 0.0011
2931 Dihydrofolate reductase folA 0.0011
3544 Dihydrofolate reductase folA 0.0011
3682 Dihydrofolate reductase folA 0.0011
6642 Dihydrofolate reductase folA 0.0011
6756 Dihydrofolate reductase dfrA 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
751 Potassium channel subfamily K member 6 KCNK6 0.0011
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
1039 Histone deacetylase 9 HDAC9 0.0011
6146 High affinity copper uptake protein 1 SLC31A1 0.0011
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0011
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
1360 Sphingomyelin phosphodiesterase SMPD1 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.001
54 Prothrombin F2 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4203 Histamine N-methyltransferase HNMT 0.001
4116 Dihydropteroate synthetase Not Available 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
172 Potassium channel subfamily K member 1 KCNK1 0.001
1144 Hepatocyte growth factor receptor MET 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
5300 Antigen peptide transporter 1 TAP1 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.001
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.001
908 Glutathione S-transferase theta-1 GSTT1 0.001
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0009
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0009
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0009
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
162 Retinoic acid receptor gamma-1 RARG 0.0009
6168 Solute carrier family 22 member 16 SLC22A16 0.0009
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0009
4773 Deoxycytidine kinase DCK 0.0009
1517 Beta-3 adrenergic receptor ADRB3 0.0009
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0009
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
459 Retinoic acid receptor RXR-alpha RXRA 0.0009
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
1648 Elastin ELN 0.0009
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
153 Dopamine beta-hydroxylase DBH 0.0009
183 Vascular endothelial growth factor A VEGFA 0.0009
518 Peroxidase/catalase T katG 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
3404 Exotoxin A eta 0.0008
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0008
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0008
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0008
2207 Rhodopsin RHO 0.0008
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0008
2298 Cytochrome P450-cam camC 0.0008
1867 Major prion protein PRNP 0.0008
2232 Interleukin-5 IL5 0.0008
76 Nitric-oxide synthase, brain NOS1 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
6163 Copper-transporting ATPase 2 ATP7B 0.0008
6165 Copper-transporting ATPase 1 ATP7A 0.0008
1025 Aquaporin-1 AQP1 0.0008
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0008
3856 Fibroblast growth factor receptor 3 FGFR3 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0007
130 Prostacyclin synthase PTGIS 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
6103 Arylamine N-acetyltransferase 1 NAT1 0.0007
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0007
2981 Phospholipase A2, membrane associated PLA2G2A 0.0007
2112 Toll-like receptor 9 TLR9 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
5924 Microtubule-associated protein 4 MAP4 0.0007
5923 Microtubule-associated protein tau MAPT 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
24 Thymidylate synthase TMP1 0.0007
359 Thymidylate synthase TYMS 0.0007
2626 Thymidylate synthase thyA 0.0007
2729 Thymidylate synthase thyA 0.0007
5352 Thymidylate synthase THYA 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0007
164 Histamine H4 receptor HRH4 0.0007
125 DNA polymerase beta POLB 0.0007
4311 tRNA TRDMT1 0.0007
4325 tRNA trmD 0.0007
4328 tRNA trmD 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0006
144 Hemoglobin subunit alpha HBA1 0.0006
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0006
106 Cannabinoid receptor 2 CNR2 0.0006
6174 50S ribosomal protein L32 rpmF 0.0006
273 Apoptosis regulator Bcl-2 BCL2 0.0006
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0006
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0006
1196 Complement decay-accelerating factor CD55 0.0006
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0006
3426 Glutamine synthetase glnA 0.0006
3987 Glutamine synthetase GLUL 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
4192 DNA topoisomerase 2-beta TOP2B 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
3611 Cytidine deaminase cdd 0.0006
3707 Cytidine deaminase cdd 0.0006
4211 Cytidine deaminase CDA 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
634 Squalene monooxygenase SQLE 0.0006
7196 Squalene monooxygenase ERG1 0.0006
4210 Toll-like receptor 4 TLR4 0.0005
2808 Chloramphenicol acetyltransferase 3 cat3 0.0005
1341 Histamine H3 receptor HRH3 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0005
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
3810 Catechol O-methyltransferase COMT 0.0005
2417 Chloramphenicol acetyltransferase cat 0.0005
3278 Chloramphenicol acetyltransferase cat 0.0005
2810 Dr hemagglutinin structural subunit draA 0.0005
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0005
3601 Dihydropteroate synthase 1 folP1 0.0005
3807 Dihydropteroate synthase 1 folP1 0.0005
3808 Dihydropteroate synthase 2 folP2 0.0005
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0005
1714 Mitogen-activated protein kinase 3 MAPK3 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
3913 Glutamic acid decarboxylase GAD65 0.0005
6149 Solute carrier family 22 member 10 SLC22A10 0.0005
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0004
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
4925 Cytochrome c-type protein SHP shp 0.0004
4954 Soluble cytochrome b558 Not Available 0.0004
4916 Cyanoglobin glbN 0.0004
4994 Hemoglobin-like protein HbO glbO 0.0004
4915 Cytochrome c-550 psbV 0.0004
4959 Cytochrome c-550 psbV 0.0004
5216 Cytochrome c-550 psbV 0.0004
4943 Cytochrome c6 petJ 0.0004
4984 Neuroglobin NGB 0.0004
3116 Bacterioferritin bfr 0.0004
4906 Bacterioferritin bfr 0.0004
4965 Bacterioferritin bfr 0.0004
4947 Bacterial hemoglobin vhb 0.0004
4975 Cytochrome c-556 RPA3973 0.0004
4934 Cytochrome c-551 nirM 0.0004
5218 Cytochrome c-551 nirM 0.0004
4936 Cytochrome c2 iso-2 Not Available 0.0004
4905 Cytochrome c2 Not Available 0.0004
4939 Cytochrome c2 cycA 0.0004
4964 Cytochrome c2 cycA 0.0004
4979 Cytochrome c2 cycA 0.0004
6673 Cytochrome c2 cycA 0.0004
4910 Cytoglobin CYGB 0.0004
4981 Iron-starvation protein PigA pigA 0.0004
4909 CooA protein cooA 0.0004
4907 Cytochrome c-L moxG 0.0004
6865 Cytochrome c-L moxG 0.0004
4998 Hemoglobin-like protein yjbI yjbI 0.0004
5000 HemO hemO 0.0004
4942 Diheme cytochrome c napB napB 0.0004
4935 Cytochrome c-554 cycA1 0.0004
644 Heme oxygenase 2 HMOX2 0.0004
4982 Heme oxygenase 2 pbsA2 0.0004
4972 P450cin cinA 0.0004
4904 Cytochrome c family protein GSU1996 0.0004
4971 Nonaheme cytochrome c hmcA 0.0004
4961 Hemophore HasA hasA 0.0004
4976 Apocytochrome f petA 0.0004
6407 Apocytochrome f petA 0.0004
4931 Cytochrome P450 167A1 CYP167A1 0.0004
4960 Putative cytochrome P450-family protein SCO7417 0.0004
4764 Cytochrome P450 165C4 CYP165C4 0.0004
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0004
4903 Methyl-accepting chemotaxis protein Tar4 0.0004
4926 Heme-based aerotactic transducer hemAT hemAT 0.0004
4999 Cytochrome P450 165B3 CYP165B3 0.0004
4993 Hydroxylamine oxidoreductase hao1 0.0004
4989 Cytochrome c551 peroxidase ccp 0.0004
5222 Cytochrome c551 peroxidase ccpA 0.0004
4937 Cytochrome oxidase subunit II rcoxA 0.0004
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0004
4922 Cytochrome c, putative SO_4144 0.0004
4952 Catalase/peroxidase katA 0.0004
3093 Catalase HPII katE 0.0004
4103 Proteasome subunit beta type 2 PSMB2 0.0004
4101 Proteasome subunit beta type 1 PSMB1 0.0004
4102 Proteasome subunit beta type 5 PSMB5 0.0004
976 Platelet glycoprotein IX GP9 0.0004
1374 Natriuretic peptides B NPPB 0.0004
1827 Gap junction alpha-1 protein GJA1 0.0004
1908 Vascular cell adhesion protein 1 VCAM1 0.0004
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
4217 Telomerase reverse transcriptase TERT 0.0004
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0004
735 Alanine aminotransferase 1 GPT 0.0004
3904 Alanine aminotransferase 2 GPT2 0.0004
511 5-hydroxytryptamine 1F receptor HTR1F 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
6048 Troponin C, skeletal muscle TNNC2 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0003
268 Adenosine A2b receptor ADORA2B 0.0003
828 Phenylalanine-4-hydroxylase PAH 0.0003
3109 Phenylalanine-4-hydroxylase phhA 0.0003
6044 Serum paraoxonase/lactonase 3 PON3 0.0003
758 Thyroid hormone receptor alpha THRA 0.0003
33 Cystine/glutamate transporter SLC7A11 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0003
572 Integrin alpha-L ITGAL 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0003
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0003
2320 Thymidine kinase, cytosolic TK1 0.0003
4920 Peroxidase/catalase katG 0.0003
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0003
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0003
4948 Cytochrome c-553 Not Available 0.0003
4923 Cytochrome c3 DvMF_2499 0.0003
4945 Cytochrome c3 Not Available 0.0003
4949 Cytochrome c3 DVU_3171 0.0003
4968 Cytochrome c3 cytc3 0.0003
4997 Cytochrome c3 SO_2727 0.0003
5219 Cytochrome c3 cyd 0.0003
4902 Nine-heme cytochrome c Ddes_2038 0.0003
2119 Cytochrome b5 CYB5A 0.0003
4990 PpcA ppcA 0.0003
3189 High-molecular-weight cytochrome c hmcA 0.0003
3375 Acidic cytochrome c3 Not Available 0.0003
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0003
4988 Sulfite oxidase, mitochondrial SUOX 0.0003
2915 Sensor protein fixL fixL 0.0003
4944 Sensor protein fixL fixL 0.0003
4385 Cytochrome c' Not Available 0.0003
4967 Cytochrome c' cycA 0.0003
5038 Cytochrome c' Not Available 0.0003
5223 Cytochrome c' cycP 0.0003
4813 Heme oxygenase hmuO 0.0003
5769 Heme oxygenase Not Available 0.0003
3570 Cytochrome P450 152A1 cypC 0.0003
4037 Hypothetical protein GPX1 0.0003
4297 Hypothetical protein SP_1951 0.0003
4521 Hypothetical protein BC_2969 0.0003
4540 Hypothetical protein TM_1070 0.0003
4555 Hypothetical protein MT1739 0.0003
4569 Hypothetical protein mshD 0.0003
4578 Hypothetical protein PA3270 0.0003
4747 Hypothetical protein PA3967 0.0003
5177 Hypothetical protein TM_0096 0.0003
5194 Hypothetical protein PA1204 0.0003
5240 Hypothetical protein Rv2991 0.0003
5370 Hypothetical protein TM_1158 0.0003
5710 Hypothetical protein Tb927.5.1360 0.0003
4289 Cytochrome P450 TT_P0059 0.0003
6262 Cytochrome P450 staP 0.0003
4992 Cytochrome c peroxidase Not Available 0.0003
1864 RET proto-oncogene RET 0.0003
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0003
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0003
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
2230 Catalase CAT 0.0003
3249 Catalase katA 0.0003
3625 Catalase katA 0.0003
4539 Catalase katA 0.0003
4941 Catalase katB 0.0003
1275 Estrogen sulfotransferase SULT1E1 0.0003
760 Fibroblast growth factor 1 FGF1 0.0003
6218 Pannexin-1 PANX1 0.0003
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0003
3411 Cytochrome P450 121 cyp121 0.0003
3670 Soluble cytochrome b562 precursor cybC 0.0003
3291 Cytochrome c-552 cycA 0.0003
4927 Cytochrome c-552 nrfA 0.0003
4938 Cytochrome c-552 cycA 0.0003
4953 Cytochrome c-552 nrfA 0.0003
5217 Cytochrome c-552 cycM 0.0003
2617 Nitric oxide synthase oxygenase nos 0.0003
2701 Nitric oxide synthase oxygenase nos 0.0003
4386 Hemoglobin-like protein HbN glbN 0.0003
3102 Flavohemoprotein hmp 0.0003
4969 Flavohemoprotein hmp 0.0003
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0003
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0002
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0002
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0002
3127 Nitrite reductase nirS 0.0002
3284 Nitrite reductase nirS 0.0002
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0002
3221 Cytochrome c4 cc4 0.0002
2972 6-deoxyerythronolide B hydroxylase eryF 0.0002
3957 Adenosine deaminase ADA 0.0002
4608 Putative cytochrome P450 SCO1207 0.0002
4963 Putative cytochrome P450 SCO2884 0.0002
6254 Putative cytochrome P450 SCO6998 0.0002
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0002
358 Cystathionine beta-synthase CBS 0.0002
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0002
1507 Cytochrome c CYCS 0.0002
693 Hemoglobin subunit beta HBB 0.0002
6268 Hydroxyacid oxidase 1 HAO1 0.0002
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0002
810 Heme oxygenase 1 HMOX1 0.0002
3391 Heme oxygenase 1 pbsA1 0.0002
489 Monocarboxylate transporter 2 SLC16A7 0.0002
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0001
↑