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Listeriolysin regulatory protein


Partner ID 2280
Name Listeriolysin regulatory protein
Synonyms 4005
Gene name prfA
General function Signal transduction mechanisms
Specific function Positively regulates expression of listeriolysin, of 1- phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors
Gene sequence + ...

ATGAACGCTCAAGCAGAAGAATTCAAAAAATATTTAGAAACTAACGGGATAAAACCAAAACAATTTCATAAAAAAGAACTTATTTTTAACCAATGGGATCCACAAGAATATTGTATTTTTCTATATGATGGTATCACAAAGCTCACGAGTATTAGCGAGAACGGGACCATCATGAATTTACAATACTACAAAGGGGCTTTCGTTATAATGTCTGGCTTTATTGATACAGAAACATCGGTTGGCTATTATAATTTAGAAGTCATTAGCGAGCAGGCTACCGCATACGTTATCAAAATAAACGAACTAAAAGAACTACTGAGCAAAAATCTTACGCACTTTTTCTATGTTTTCCAAACCCTACAAAAACAAGTTTCATACAGTCTAGCTAAATTTAATGATTTTTCGATTAACGGGAAGCTTGGCTCTATTTGCGGTCAACTTTTAATCCTGACCTATGTGTATGGTAAAGAAACTCCTGATGGCATCAAGATTACACTGGATAATTTAACAATGCAGGAGTTAGGATATTCAAGTGGCATCGCACATAGCTCAGCTGTTAGCAGAATTATTTCCAAATTAAAGCAAGAGAAAGTTATCGTGTATAAAAATTCATGCTTTTATGTACAAAATCTTGATTATCTCAAAAGATATGCCCCTAAATTAGATGAATGGTTTTATTTAGCATGTCCTGCTACTTGGGGAAAATTAAATTAA
Protein sequence + ...

MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
GO Classification
component
cell
intracellular
function
binding
nucleic acid binding
transcription factor activity
DNA binding
process
regulation of metabolism
regulation of cellular metabolism
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
regulation of transcription
regulation of transcription, DNA-dependent
regulation of biological process
regulation of physiological process
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01692 Dithioerythritol
DB03654 S,S-Propylthiocysteine
DB04447 1,4-Dithiothreitol

Associated as Prediction

Id Name
DB00134 L-Methionine
DB00143 Glutathione
DB00157 NADH
DB00162 Vitamin A
DB00172 L-Proline
DB00175 Pravastatin
DB00227 Lovastatin
DB00432 Trifluridine
DB00439 Cerivastatin
DB00495 Zidovudine
DB00641 Simvastatin
DB00755 Tretinoin
DB01076 Atorvastatin
DB01095 Fluvastatin
DB01098 Rosuvastatin
DB01692 Dithioerythritol
DB01695 N-Hydroxy-4-Phosphono-Butanamide
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01992 Coenzyme A
DB02031 (6s)-5,6,7,8-Tetrahydrofolate
DB02135 4-{2,6,8-Trioxo-9-[(2r,3s,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Butyl Dihydrogen Phosphate
DB02184 (2s,3s)-1,4-Dimercaptobutane-2,3-Diol
DB02223 Ly231514 Tetra Glu
DB02256 2'-Deoxyuridine
DB02290 3-{2,6,8-Trioxo-9-[(2s,3s,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Propyl Dihydrogen Phosphate
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02379 Beta-D-Glucose
DB02452 Thymidine-5'-Triphosphate
DB02467 S-Oxymethionine
DB02693 (4s,5s)-1,2-Dithiane-4,5-Diol
DB02711 4-{2,6,8-Trioxo-9-[(2s,3r,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Butyl Dihydrogen Phosphate
DB02726 2-Phosphoglycolic Acid
DB02752 Tosyl-D-Proline
DB02772 Sucrose
DB02899 N-Carboxymethionine
DB03022 3-{2,6,8-Trioxo-9-[(2r,3s,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Propyl Dihydrogen Phosphate
DB03026 Phosphoglycolohydroxamic Acid
DB03038 LY341770
DB03132 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
DB03135 [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
DB03157 N,O-Didansyl-L-Tyrosine
DB03169 (S)-Hmg-Coa
DB03274 2'-5'dideoxyuridine
DB03314 Fluorotryptophane
DB03379 2-Carboxyethylphosphonic Acid
DB03431 Adenosine-5'-Diphosphate
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03541 10-Propargyl-5,8-Dideazafolic Acid
DB03558 Sp-876
DB03654 S,S-Propylthiocysteine
DB03761 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
DB03800 2'-deoxyuridylic acid
DB03811 Histidinol
DB03812 3-{2,6,8-Trioxo-9-[(2s,3r,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Propyl Dihydrogen Phosphate
DB03818 N-[Tosyl-D-Prolinyl]Amino-Ethanethiol
DB03900 2-Methyl-2-Propanol
DB03973 3-{2,6,8-Trioxo-9-[(2r,3r,4r)-2,3,4,5-Tetrahydroxypentyl]-1,2,3,6,8,9-Hexahydro-7h-Purin-7-Yl}Propyl Dihydrogen Phosphate
DB04077 Glycerol
DB04119 Hexatantalum Dodecabromide
DB04205 Thymidine-3',5'-Diphosphate
DB04272 Citric Acid
DB04326 1,3-Dihydroxyacetonephosphate
DB04377 3-Hydroxy-3-Methyl-Glutaric Acid
DB04447 1,4-Dithiothreitol
DB04457 2'-Deoxyguanosine-5'-Monophosphate
DB04503 Sp-722
DB04510 3-Phosphoglyceric Acid
DB04530 S,S-(2-Hydroxyethyl)Thiocysteine
DB04586 2-bromophenol
DB04696 4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN
DB06693 Mevastatin
DB06846 7-[3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOL-2-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
DB07387 3-(BUTYLSULPHONYL)-PROPANOIC ACID
DB07766 (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}
DB08016 4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE
DB08131 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
DB08860 Pitavastatin
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