DT-Web

DB00214 - Torasemide


Identification
Name Torasemide
Accession Number DB00214 (APRD00217, APRD00295)
Type small molecule
Description Torasemide (rINN) or torsemide (USAN) is a pyridine-sulfonylurea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension. It is marketed under the brand name Demadex. [Wikipedia]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 348.42
Groups approved
Monoisotopic Weight 348.125611216
Pharmacology
Indication For the treatment of edema associated with congestive heart failure, renal disease, or hepatic disease. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
Mechanism of action Torasemide inhibits the Na+/K+/2Cl--carrier system (via interference of the chloride binding site) in the lumen of the thick ascending portion of the loop of Henle, resulting in a decrease in reabsorption of sodium and chloride. This results in an increase in the rate of delivery of tubular fluid and electrolytes to the distal sites of hydrogen and potassium ion secretion, while plasma volume contraction increases aldosterone production. The increased delivery and high aldosterone levels promote sodium reabsorption at the distal tubules, and By increasing the delivery of sodium to the distal renal tubule, torasemide indirectly increases potassium excretion via the sodium-potassium exchange mechanism. Torasemide's effects in other segments of the nephron have not been demonstrated. Thus torasemide increases the urinary excretion of sodium, chloride, and water, but it does not significantly alter glomerular filtration rate, renal plasma flow, or acid-base balance. Torasemide's effects as a antihypertensive are due to its diuretic actions. By reducing extracellular and plasma fluid volume, blood pressure is reduced temporarily, and cardiac output also decreases.
Absorption Rapidly absorbed following oral administration. Absolute bioavailability is 80%. Food has no effect on absorption.
Protein binding > 99%
Biotransformation Metabolized via the hepatic CYP2C8 to 5 metabolites. The major metabolite, M5, is pharmacologically inactive. There are 2 minor metabolites, M1, possessing one-tenth the activity of torasemide, and M3, equal in activity to torasemide. Overall, torasemide appears to account for 80% of the total diuretic activity, while metabolites M1 and M3 account for 9% and 11%, respectively.
Route of elimination Torsemide is cleared from the circulation by both hepatic metabolism (approximately 80% of total clearance) and excretion into the urine (approximately 20% of total clearance in patients with normal renal function).
Toxicity Symptoms of overdose include dehydration, hypovolemia, hypotension, hyponatremia, hypokalemia, hypochloremic alkalosis, and hemoconcentration. Oral LD50 in rat is 5 g/kg, and intravenous LD50 in rat is 500 mg/kg.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Amifostine Torasemide may increase the hypotensive effect of Amifostine. At chemotherapeutic doses of Amifostine, Torasemide should be withheld for 24 hours prior to Amifostine administration. Use caution at lower doses of Amifostine.
Amikacin Increased ototoxicity
Capecitabine Capecitabine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Capecitabine is initiated, discontinued or dose changed.
Cholestyramine Cholestyramine may decrease the bioavailability of Torasemide by inhibiting Torasemide absorption. Monitor for changes in the therapeutic and adverse effects of Torasemide if Cholestyramine is initiated, discontinued or dose changed. Spacing administration by at least 2 hours may reduce the risk of interaction.
Colesevelam Colesevelam may decrease the bioavailability of Torasemide by inhibiting Torasemide absorption. Monitor for changes in the therapeutic and adverse effects of Torasemide if Colesevelam is initiated, discontinued or dose changed. Spacing administration by at least 2 hours may reduce the risk of interaction.
Colestipol Colestipol may decrease the bioavailability of Torasemide by inhibiting Torasemide absorption. Monitor for changes in the therapeutic and adverse effects of Torasemide if Colestipol is initiated, discontinued or dose changed. Spacing administration by at least 2 hours may reduce the risk of interaction.
Delavirdine Delavirdine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Delavirdine is initiated, discontinued or dose changed.
Floxuridine Floxuridine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Floxuridine is initiated, discontinued or dose changed.
Fluconazole Fluconazole, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Fluconazole is initiated, discontinued or dose changed.
Fluorouracil Fluorouracil, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Fluorouracil is initiated, discontinued or dose changed.
Flurbiprofen Flurbiprofen, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Flurbiprofen is initiated, discontinued or dose changed.
Gemfibrozil Gemfibrozil, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Gemfibrozil is initiated, discontinued or dose changed.
Gentamicin Increased ototoxicity
Ibuprofen The NSAID, ibuprofen, may decrease the diuretic and antihypertensive effect of the loop diuretic, torasemide.
Indomethacin The NSAID, indomethacin, may decrease the diuretic and antihypertensive effects of the loop diuretic, torasemide.
Ketoconazole Ketoconazole, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Ketoconazole is initiated, discontinued or dose changed.
Mefenamic acid Mefanamic acid, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Mefanamic acid is initiated, discontinued or dose changed.
Miconazole Miconazole, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Miconazole is initiated, discontinued or dose changed.
Netilmicin Increased ototoxicity
Nicardipine Nicardipine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Nicardipine is initiated, discontinued or dose changed.
Piroxicam Piroxicam, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Piroxicam is initiated, discontinued or dose changed.
Rituximab Additive antihypertensive effects may occur. Increased risk of hypotension. Consider withholding Torasemide for 12 hours prior to administration of Rituximab.
Sitaxentan Sitaxsentan, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Sitaxsentan is initiated, discontinued or dose changed.
Sulfadiazine Sulfadiazine, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Sulfadiazine is initiated, discontinued or dose changed.
Sulfisoxazole Sulfisoxazole, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Sulfisoxazole is initiated, discontinued or dose changed.
Tobramycin Increased ototoxicity
Tolbutamide Tolbutamide, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing its metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Tolbutamide is initiated, discontinued or dose changed.
Trandolapril The loop diuretic, Torasemide, may increase the hypotensive effect of Trandolapril. Torasemide may also increase the nephrotoxicity of Trandolapril.
Treprostinil Additive hypotensive effect. Monitor antihypertensive therapy during concomitant use.
Food Interactions Not Available

Targets


Solute carrier family 12 member 1
Name Solute carrier family 12 member 1
Gene Name SLC12A1
Pharmacological action yes
Actions inhibitor
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Vormfelde SV, Sehrt D, Toliat MR, Schirmer M, Meineke I, Tzvetkov M, Nurnberg P, Brockmoller J: Genetic variation in the renal sodium transporters NKCC2, NCC, and ENaC in relation to the effects of loop diuretic drugs. Clin Pharmacol Ther. 2007 Sep;82(3):300-9. Epub 2007 Apr 25. - Pubmed
  • Fortuno A, Muniz P, Ravassa S, Rodriguez JA, Fortuno MA, Zalba G, Diez J: Torasemide inhibits angiotensin II-induced vasoconstriction and intracellular calcium increase in the aorta of spontaneously hypertensive rats. Hypertension. 1999 Jul;34(1):138-43. - Pubmed
DTHybrid score 0.5086

Enzymes


Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions substrate
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2832
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4175
Prostaglandin G/H synthase 1
Name Prostaglandin G/H synthase 1
Gene Name PTGS1
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
DTHybrid score 0.4582
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3184

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.2378
290 Prostaglandin G/H synthase 2 PTGS2 0.1783
4119 Cytochrome P450 2D6 CYP2D6 0.1601
4200 Cytochrome P450 1A2 CYP1A2 0.145
1588 Multidrug resistance protein 1 ABCB1 0.1104
6030 Cytochrome P450 2B6 CYP2B6 0.1007
4118 Cytochrome P450 3A5 CYP3A5 0.0992
587 Serum albumin ALB 0.0954
6013 Cytochrome P450 2E1 CYP2E1 0.0894
1729 Solute carrier family 22 member 6 SLC22A6 0.0765
6107 Cytochrome P450 3A7 CYP3A7 0.0706
295 Carbonic anhydrase 1 CA1 0.0683
5718 Cytochrome P450 2A6 CYP2A6 0.0629
310 Solute carrier family 12 member 2 SLC12A2 0.0618
357 Carbonic anhydrase 2 CA2 0.0588
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0559
592 Carbonic anhydrase 4 CA4 0.0552
6024 Cytochrome P450 1A1 CYP1A1 0.054
6106 Cytochrome P450 2C18 CYP2C18 0.0488
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0473
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.044
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0411
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0399
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0393
6142 Solute carrier family 22 member 8 SLC22A8 0.0375
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0353
53 Solute carrier family 12 member 5 SLC12A5 0.0343
663 Solute carrier family 12 member 4 SLC12A4 0.0343
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0337
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0313
1024 Solute carrier family 22 member 11 SLC22A11 0.0311
275 Arachidonate 5-lipoxygenase ALOX5 0.0299
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0285
1181 Alpha-1-acid glycoprotein 1 ORM1 0.026
2164 Multidrug resistance-associated protein 4 ABCC4 0.0257
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0253
492 Histamine H1 receptor HRH1 0.0252
304 Solute carrier family 12 member 7 SLC12A7 0.0243
157 Solute carrier family 12 member 6 SLC12A6 0.0242
6143 Solute carrier family 22 member 7 SLC22A7 0.0242
862 Multidrug resistance-associated protein 1 ABCC1 0.0232
824 Sodium-dependent serotonin transporter SLC6A4 0.0226
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0224
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0222
466 Solute carrier family 12 member 3 SLC12A3 0.0222
3932 Glutathione S-transferase A2 GSTA2 0.0214
1898 Cytochrome P450 1B1 CYP1B1 0.0206
3811 Cytochrome P450 19A1 CYP19A1 0.0203
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.02
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0199
1405 Thiopurine S-methyltransferase TPMT 0.0178
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0178
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0176
70 Type-1 angiotensin II receptor AGTR1 0.0173
118 Organic cation/carnitine transporter 2 SLC22A5 0.0172
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0172
260 Cytochrome P450 51 ERG11 0.017
761 Cytochrome P450 51 ERG11 0.017
3163 Cytochrome P450 51 cyp51 0.017
1757 Myeloperoxidase MPO 0.0169
891 Dihydropteroate synthase folP 0.0168
5359 Dihydropteroate synthase folP 0.0168
7175 Dihydropteroate synthase sulI 0.0168
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0168
6144 Solute carrier family 22 member 2 SLC22A2 0.0168
6145 Solute carrier family 22 member 1 SLC22A1 0.0162
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0161
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0158
6141 Sodium/bile acid cotransporter SLC10A1 0.0156
136 Estrogen receptor ESR1 0.0155
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0152
3007 Carbonic anhydrase 12 CA12 0.0151
4205 Carbonic anhydrase 9 CA9 0.0151
502 5-hydroxytryptamine 2A receptor HTR2A 0.0149
776 Bile salt export pump ABCB11 0.0148
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0146
731 HIV-1 protease HIV-1 protease 0.0145
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0144
146 Androgen receptor AR 0.0143
122 P2Y purinoceptor 12 P2RY12 0.0136
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0135
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0135
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0135
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0131
831 D(2) dopamine receptor DRD2 0.0131
3941 Amine oxidase [flavin-containing] A MAOA 0.0131
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0129
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0128
6102 Arylamine N-acetyltransferase 2 NAT2 0.0127
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0127
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0125
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0123
696 Kappa-type opioid receptor OPRK1 0.0121
51 Muscarinic acetylcholine receptor M3 CHRM3 0.012
713 Sodium-dependent dopamine transporter SLC6A3 0.012
811 Translocator protein TSPO 0.0118
373 Transthyretin TTR 0.0117
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0116
467 Delta-type opioid receptor OPRD1 0.0116
6031 Cytochrome P450 3A43 CYP3A43 0.0115
468 Cytochrome P450 4A11 CYP4A11 0.0115
766 Beta-2 adrenergic receptor ADRB2 0.0115
1507 Cytochrome c CYCS 0.0115
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0114
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0113
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0112
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0112
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0111
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0109
847 Mu-type opioid receptor OPRM1 0.0109
556 Alpha-1A adrenergic receptor ADRA1A 0.0108
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0108
341 5-hydroxytryptamine 3 receptor HTR3A 0.0107
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0105
3939 Amine oxidase [flavin-containing] B MAOB 0.0105
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0104
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0102
6182 Cytochrome P450 2J2 CYP2J2 0.0102
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0101
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0101
6085 Fatty acid-binding protein, intestinal FABP2 0.0098
2183 Fatty acid-binding protein, adipocyte FABP4 0.0098
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0097
590 5-hydroxytryptamine 2C receptor HTR2C 0.0096
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0096
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0092
4116 Dihydropteroate synthetase Not Available 0.0087
738 Monocarboxylate transporter 1 SLC16A1 0.0087
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0086
632 Alpha-1B adrenergic receptor ADRA1B 0.0086
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0086
3312 Fatty acid-binding protein, brain FABP7 0.0086
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0086
23 D(1A) dopamine receptor DRD1 0.0085
427 Substance-P receptor TACR1 0.0084
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0084
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0083
465 Calmodulin CALM1 0.0083
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0082
6136 Multidrug resistance-associated protein 5 ABCC5 0.0081
6137 Multidrug resistance-associated protein 6 ABCC6 0.008
777 Tumor necrosis factor TNF 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
320 5-hydroxytryptamine 1A receptor HTR1A 0.0078
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0076
365 Dihydrofolate reductase DHFR 0.0076
2381 Dihydrofolate reductase DFR1 0.0076
2833 Dihydrofolate reductase Not Available 0.0076
2931 Dihydrofolate reductase folA 0.0076
3544 Dihydrofolate reductase folA 0.0076
3682 Dihydrofolate reductase folA 0.0076
6642 Dihydrofolate reductase folA 0.0076
6756 Dihydrofolate reductase dfrA 0.0076
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0075
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0075
6147 Solute carrier family 22 member 3 SLC22A3 0.0075
3923 Cholinesterase BCHE 0.0074
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0073
504 Mast/stem cell growth factor receptor KIT 0.0073
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0072
1648 Elastin ELN 0.0072
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0071
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0071
49 Endothelin B receptor EDNRB 0.007
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.007
318 Alpha-2A adrenergic receptor ADRA2A 0.0069
380 Cytochrome P450 17A1 CYP17A1 0.0068
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0068
844 Epidermal growth factor receptor EGFR 0.0068
817 DNA topoisomerase 2-alpha TOP2A 0.0066
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0066
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0066
578 Endothelin-1 receptor EDNRA 0.0066
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0065
130 Prostacyclin synthase PTGIS 0.0065
871 Glucocorticoid receptor NR3C1 0.0065
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0064
6014 Cytochrome P450 2A13 CYP2A13 0.0064
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0064
4604 Liver carboxylesterase 1 CES1 0.0064
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0064
133 Dihydropterate synthase sulI 0.0063
193 Beta-1 adrenergic receptor ADRB1 0.0063
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0062
789 Alpha-1D adrenergic receptor ADRA1D 0.0062
921 Glutamate receptor 2 GRIA2 0.0061
823 Fibroblast growth factor receptor 2 FGFR2 0.0061
885 5-hydroxytryptamine 1B receptor HTR1B 0.0061
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.006
6148 Multidrug resistance-associated protein 7 ABCC10 0.006
1541 Metalloproteinase mmp20 0.006
183 Vascular endothelial growth factor A VEGFA 0.006
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0058
362 Melatonin receptor type 1B MTNR1B 0.0058
571 Melatonin receptor type 1A MTNR1A 0.0058
407 Vascular endothelial growth factor receptor 2 KDR 0.0058
6103 Arylamine N-acetyltransferase 1 NAT1 0.0058
3810 Catechol O-methyltransferase COMT 0.0058
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0057
703 NADPH azoreductase azr 0.0056
124 Histamine H2 receptor HRH2 0.0056
634 Squalene monooxygenase SQLE 0.0056
7196 Squalene monooxygenase ERG1 0.0056
833 Organic cation/carnitine transporter 1 SLC22A4 0.0056
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0056
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0056
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0056
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0055
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0055
4120 NADPH--cytochrome P450 reductase POR 0.0055
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0055
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0055
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0055
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0055
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0054
1275 Estrogen sulfotransferase SULT1E1 0.0054
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0053
7 Nitric oxide synthase, inducible NOS2 0.0053
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0053
850 Vasopressin V1b receptor AVPR1B 0.0053
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0053
94 5-hydroxytryptamine 4 receptor HTR4 0.0053
2853 14 kDa fatty acid-binding protein Not Available 0.0053
1010 Cytochrome P450 51A1 CYP51A1 0.0053
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0052
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0052
869 Estrogen receptor beta ESR2 0.0051
725 5-hydroxytryptamine 1D receptor HTR1D 0.0051
436 5-hydroxytryptamine 2B receptor HTR2B 0.0051
228 Beta platelet-derived growth factor receptor PDGFRB 0.0051
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0051
26 Vascular endothelial growth factor receptor 3 FLT4 0.005
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.005
1629 Transcription factor AP-1 JUN 0.0049
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0049
3808 Dihydropteroate synthase 2 folP2 0.0049
3601 Dihydropteroate synthase 1 folP1 0.0049
3807 Dihydropteroate synthase 1 folP1 0.0049
6033 High affinity interleukin-8 receptor A CXCR1 0.0049
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0049
24 Thymidylate synthase TMP1 0.0048
359 Thymidylate synthase TYMS 0.0048
2626 Thymidylate synthase thyA 0.0048
2729 Thymidylate synthase thyA 0.0048
5352 Thymidylate synthase THYA 0.0048
614 Progesterone receptor PGR 0.0048
756 Sex hormone-binding globulin SHBG 0.0048
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0048
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0048
106 Cannabinoid receptor 2 CNR2 0.0048
32 Vascular endothelial growth factor receptor 1 FLT1 0.0048
185 Vasopressin V1a receptor AVPR1A 0.0046
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0046
88 Retinoic acid receptor RXR-beta RXRB 0.0046
68 Cannabinoid receptor 1 CNR1 0.0046
322 Vasopressin V2 receptor AVPR2 0.0046
6012 Tryptophan 2,3-dioxygenase TDO2 0.0045
527 Prostacyclin receptor PTGIR 0.0045
6220 Aryl hydrocarbon receptor AHR 0.0045
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0045
5300 Antigen peptide transporter 1 TAP1 0.0045
1618 High affinity nerve growth factor receptor NTRK1 0.0045
638 D(3) dopamine receptor DRD3 0.0045
528 5-hydroxytryptamine 1E receptor HTR1E 0.0044
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0044
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0044
518 Peroxidase/catalase T katG 0.0043
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0042
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0041
29 Tubulin beta-1 chain TUBB1 0.0041
6146 High affinity copper uptake protein 1 SLC31A1 0.0041
4103 Proteasome subunit beta type 2 PSMB2 0.0041
4102 Proteasome subunit beta type 5 PSMB5 0.0041
459 Retinoic acid receptor RXR-alpha RXRA 0.0041
4101 Proteasome subunit beta type 1 PSMB1 0.0041
2981 Phospholipase A2, membrane associated PLA2G2A 0.0041
4203 Histamine N-methyltransferase HNMT 0.0041
6043 Putative G-protein coupled receptor 44 GPR44 0.004
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.004
6126 Carbonic anhydrase 7 CA7 0.004
489 Monocarboxylate transporter 2 SLC16A7 0.0039
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0039
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0039
4132 Chloride channel protein ClC-Ka CLCNKA 0.0039
6149 Solute carrier family 22 member 10 SLC22A10 0.0039
6174 50S ribosomal protein L32 rpmF 0.0038
4238 50S ribosomal protein L4 rplD 0.0038
5578 50S ribosomal protein L4 rplD 0.0038
6173 50S ribosomal protein L4 rplD 0.0038
6219 50S ribosomal protein L4 rplD 0.0038
161 Tubulin beta chain TUBB 0.0038
312 Tubulin beta chain TUB2 0.0038
716 5-hydroxytryptamine 7 receptor HTR7 0.0038
1192 Sulfotransferase 1A1 SULT1A1 0.0038
1196 Complement decay-accelerating factor CD55 0.0038
1050 Bile salt sulfotransferase SULT2A1 0.0038
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0038
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0037
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0037
737 Mineralocorticoid receptor NR3C2 0.0036
2539 Tubulin alpha-1 chain TUBA4A 0.0036
208 DNA-directed RNA polymerase beta' chain rpoC 0.0036
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0036
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0035
1656 CYP2B protein CYP2B 0.0034
273 Apoptosis regulator Bcl-2 BCL2 0.0033
2808 Chloramphenicol acetyltransferase 3 cat3 0.0033
5880 Thrombopoietin receptor MPL 0.0033
952 Dipeptidyl peptidase 4 DPP4 0.0033
2021 Thrombomodulin THBD 0.0032
4784 Beta-mannosidase manB 0.0032
6695 Beta-mannosidase BT_0458 0.0032
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0032
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0032
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0032
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0032
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
482 Glycine receptor subunit alpha-1 GLRA1 0.0031
629 Alpha-2B adrenergic receptor ADRA2B 0.0031
162 Retinoic acid receptor gamma-1 RARG 0.003
2417 Chloramphenicol acetyltransferase cat 0.003
3278 Chloramphenicol acetyltransferase cat 0.003
2810 Dr hemagglutinin structural subunit draA 0.003
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.003
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.003
3809 Estrogen-related receptor gamma ESRRG 0.0029
33 Cystine/glutamate transporter SLC7A11 0.0029
4122 Histone deacetylase 2 HDAC2 0.0029
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0029
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0029
4311 tRNA TRDMT1 0.0029
4325 tRNA trmD 0.0029
4328 tRNA trmD 0.0029
511 5-hydroxytryptamine 1F receptor HTR1F 0.0029
432 D(4) dopamine receptor DRD4 0.0029
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0029
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0029
581 Cytochrome P450 2R1 CYP2R1 0.0028
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0027
2207 Rhodopsin RHO 0.0027
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
780 Retinoic acid receptor RXR-gamma RXRG 0.0027
1992 Vitamin D-binding protein GC 0.0027
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0027
1039 Histone deacetylase 9 HDAC9 0.0027
84 Nuclear receptor 0B1 NR0B1 0.0026
6500 Phospholipase A2 PLA2G1B 0.0026
319 Opioid receptor, sigma 1 OPRS1 0.0026
54 Prothrombin F2 0.0026
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0026
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0026
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0026
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0026
153 Dopamine beta-hydroxylase DBH 0.0026
85 Growth hormone receptor GHR 0.0025
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0025
3639 Thymidine phosphorylase deoA 0.0025
3936 Thymidine phosphorylase TYMP 0.0025
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0025
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0025
976 Platelet glycoprotein IX GP9 0.0025
1630 Integrin beta-2 ITGB2 0.0025
4787 Envelope glycoprotein gp160 env 0.0025
4820 Envelope glycoprotein gp160 env 0.0025
5727 Envelope glycoprotein gp160 env 0.0025
469 Annexin A1 ANXA1 0.0024
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0024
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0024
759 Free fatty acid receptor 1 FFAR1 0.0024
1818 Long-chain-fatty-acid--CoA ligase 3 ACSL3 0.0024
4217 Telomerase reverse transcriptase TERT 0.0024
6138 Multidrug resistance protein 3 ABCB4 0.0024
2297 Genome polyprotein Not Available 0.0024
2322 Genome polyprotein Not Available 0.0024
2694 Genome polyprotein Not Available 0.0024
2719 Genome polyprotein Not Available 0.0024
2860 Genome polyprotein Not Available 0.0024
2928 Genome polyprotein Not Available 0.0024
3160 Genome polyprotein Not Available 0.0024
3260 Genome polyprotein Not Available 0.0024
4783 Genome polyprotein Not Available 0.0024
5726 Genome polyprotein Not Available 0.0024
5779 Genome polyprotein Not Available 0.0024
5867 Genome polyprotein Not Available 0.0024
6253 Genome polyprotein Not Available 0.0024
6301 Genome polyprotein Not Available 0.0024
6380 Genome polyprotein Not Available 0.0024
6381 Genome polyprotein Not Available 0.0024
6437 Genome polyprotein Not Available 0.0024
6520 Genome polyprotein Not Available 0.0024
6521 Genome polyprotein Not Available 0.0024
6652 Genome polyprotein Not Available 0.0024
6734 Genome polyprotein Not Available 0.0024
6735 Genome polyprotein Not Available 0.0024
6736 Genome polyprotein Not Available 0.0024
6737 Genome polyprotein Not Available 0.0024
6738 Genome polyprotein Not Available 0.0024
6739 Genome polyprotein Not Available 0.0024
6744 Genome polyprotein Not Available 0.0024
6748 Genome polyprotein Not Available 0.0024
6894 Genome polyprotein Not Available 0.0024
6898 Genome polyprotein Not Available 0.0024
229 Retinoic acid receptor beta RARB 0.0024
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
16 Adenosine A1 receptor ADORA1 0.0023
730 Retinoic acid receptor alpha RARA 0.0023
1178 Adenosine A2a receptor ADORA2A 0.0023
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0023
239 Coagulation factor X F10 0.0023
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0023
723 Cytosolic phospholipase A2 PLA2G4A 0.0023
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0023
1864 RET proto-oncogene RET 0.0023
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0023
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0023
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0023
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0023
904 Glutathione S-transferase P GSTP1 0.0023
6131 Carbonic anhydrase 14 CA14 0.0022
1792 Tissue-type plasminogen activator PLAT 0.0022
563 Thyroid peroxidase TPO 0.0022
174 Sigma 1-type opioid receptor SIGMAR1 0.0022
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0022
1374 Natriuretic peptides B NPPB 0.0022
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0022
1827 Gap junction alpha-1 protein GJA1 0.0022
1908 Vascular cell adhesion protein 1 VCAM1 0.0022
3480 Mannan endo-1,4-beta-mannosidase manA 0.0022
3086 Plasmepsin-2 Not Available 0.0022
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0022
1714 Mitogen-activated protein kinase 3 MAPK3 0.0022
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0021
3437 Eosinophil lysophospholipase CLC 0.0021
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0021
165 FL cytokine receptor FLT3 0.0021
1053 BC269730_2 FADS1 0.0021
1395 Sodium/calcium exchanger 1 SLC8A1 0.0021
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0021
5787 Angiopoietin-1 receptor TEK 0.0021
3913 Glutamic acid decarboxylase GAD65 0.0021
6044 Serum paraoxonase/lactonase 3 PON3 0.0021
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.002
856 Vitamin D3 receptor VDR 0.002
908 Glutathione S-transferase theta-1 GSTT1 0.002
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.002
1650 Heme carrier protein 1 SLC46A1 0.0019
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0019
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0019
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0019
572 Integrin alpha-L ITGAL 0.0019
1483 Membrane copper amine oxidase AOC3 0.0019
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0019
5798 Mitogen-activated protein kinase 11 MAPK11 0.0019
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0019
2320 Thymidine kinase, cytosolic TK1 0.0019
267 Plasminogen activator inhibitor 1 SERPINE1 0.0019
164 Histamine H4 receptor HRH4 0.0019
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0019
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0019
6042 Prostaglandin reductase 2 PTGR2 0.0018
1253 Interferon gamma IFNG 0.0018
2236 Casein kinase II subunit alpha CSNK2A1 0.0018
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0018
3856 Fibroblast growth factor receptor 3 FGFR3 0.0018
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0018
378 Alpha-2C adrenergic receptor ADRA2C 0.0018
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0017
6020 Aldehyde oxidase AOX1 0.0017
4192 DNA topoisomerase 2-beta TOP2B 0.0017
735 Alanine aminotransferase 1 GPT 0.0017
3904 Alanine aminotransferase 2 GPT2 0.0017
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
2112 Toll-like receptor 9 TLR9 0.0017
594 Thyroxine-binding globulin SERPINA7 0.0017
992 Protein tyrosine kinase 2 beta PTK2B 0.0017
6218 Pannexin-1 PANX1 0.0017
3830 Calreticulin CALR 0.0017
6221 Steroid hormone receptor ERR1 ESRRA 0.0017
5934 Cytochrome P450 26A1 CYP26A1 0.0017
633 Penicillin-binding proteins 1A/1B pbpA 0.0016
6432 Transporter snf 0.0016
4226 Uridine phosphorylase 2 UPP2 0.0016
1256 5-hydroxytryptamine 6 receptor HTR6 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
814 Ryanodine receptor 1 RYR1 0.0016
6034 Hydroxyindole O-methyltransferase ASMT 0.0016
6035 Nuclear receptor ROR-beta RORB 0.0016
6036 Eosinophil peroxidase EPX 0.0016
822 Aldose reductase AKR1B1 0.0016
758 Thyroid hormone receptor alpha THRA 0.0015
163 D(1B) dopamine receptor DRD5 0.0015
4785 Ig gamma-1 chain C region IGHG1 0.0015
3937 Fatty-acid amide hydrolase FAAH 0.0015
3947 Xanthine dehydrogenase/oxidase XDH 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0015
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0015
4225 Uridine phosphorylase 1 UPP1 0.0015
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0015
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0015
936 Ephrin type-A receptor 2 EPHA2 0.0015
3611 Cytidine deaminase cdd 0.0014
3707 Cytidine deaminase cdd 0.0014
4211 Cytidine deaminase CDA 0.0014
199 Monocarboxylate transporter 8 SLC16A2 0.0014
6048 Troponin C, skeletal muscle TNNC2 0.0014
1313 Lactoylglutathione lyase GLO1 0.0014
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
268 Adenosine A2b receptor ADORA2B 0.0014
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0014
65 Matrix metalloproteinase-9 Not Available 0.0014
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0014
413 Amidophosphoribosyltransferase PPAT 0.0014
2515 Amidophosphoribosyltransferase purF 0.0014
3714 Amidophosphoribosyltransferase purF 0.0014
251 Alcohol dehydrogenase 1A ADH1A 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
2300 Lysozyme E 0.0014
3633 Lysozyme R 0.0014
5597 Lysozyme 17 0.0014
765 Indoleamine 2,3-dioxygenase IDO1 0.0014
346 Thyroid hormone receptor beta-1 THRB 0.0014
2232 Interleukin-5 IL5 0.0014
1291 cAMP response element-binding protein CREB1 0.0014
1593 Mucin-2 MUC2 0.0014
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0013
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0013
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0013
818 50S ribosomal protein L10 rplJ 0.0013
820 Glycine receptor subunit alpha-2 GLRA2 0.0013
4210 Toll-like receptor 4 TLR4 0.0013
284 DNA-directed RNA polymerase beta chain rpoB 0.0013
5773 DNA-directed RNA polymerase beta chain rpoB 0.0013
1262 Corticotropin-lipotropin POMC 0.0013
3426 Glutamine synthetase glnA 0.0013
3987 Glutamine synthetase GLUL 0.0013
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0013
5923 Microtubule-associated protein tau MAPT 0.0013
5924 Microtubule-associated protein 4 MAP4 0.0013
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0012
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0012
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0012
569 Retinal dehydrogenase 2 ALDH1A2 0.0012
444 Alcohol dehydrogenase 1B ADH1B 0.0012
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0012
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0012
5433 UPF0230 protein TM_1468 TM_1468 0.0012
5431 Lipid binding protein Not Available 0.0012
3616 Fatty acid-binding protein, epidermal FABP5 0.0012
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0012
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0012
1852 Microtubule-associated protein 2 MAP2 0.0012
4948 Cytochrome c-553 Not Available 0.0012
4923 Cytochrome c3 DvMF_2499 0.0012
4945 Cytochrome c3 Not Available 0.0012
4949 Cytochrome c3 DVU_3171 0.0012
4968 Cytochrome c3 cytc3 0.0012
4997 Cytochrome c3 SO_2727 0.0012
5219 Cytochrome c3 cyd 0.0012
4902 Nine-heme cytochrome c Ddes_2038 0.0012
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0012
3189 High-molecular-weight cytochrome c hmcA 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
474 Acetylcholinesterase ACHE 0.0011
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
751 Potassium channel subfamily K member 6 KCNK6 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0011
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0011
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0011
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0011
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0011
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0011
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0011
517 Alcohol dehydrogenase 1C ADH1C 0.001
3917 Methylenetetrahydrofolate reductase MTHFR 0.001
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.001
283 SEC14-like protein 2 SEC14L2 0.001
4386 Hemoglobin-like protein HbN glbN 0.001
172 Potassium channel subfamily K member 1 KCNK1 0.001
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.001
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.001
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.001
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0009
2211 Fatty acid-binding protein, heart FABP3 0.0009
6459 Glycodelin PAEP 0.0009
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0009
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0009
2216 Fibroblast growth factor receptor 4 FGFR4 0.0009
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0009
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0009
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0009
3957 Adenosine deaminase ADA 0.0009
1341 Histamine H3 receptor HRH3 0.0009
537 ATP synthase delta chain, mitochondrial ATP5D 0.0009
3221 Cytochrome c4 cc4 0.0009
6677 Myelin P2 protein PMP2 0.0009
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0009
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0009
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0009
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
1184 Interferon beta IFNB1 0.0008
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0008
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
4954 Soluble cytochrome b558 Not Available 0.0008
4916 Cyanoglobin glbN 0.0008
4947 Bacterial hemoglobin vhb 0.0008
4934 Cytochrome c-551 nirM 0.0008
5218 Cytochrome c-551 nirM 0.0008
4943 Cytochrome c6 petJ 0.0008
4915 Cytochrome c-550 psbV 0.0008
4959 Cytochrome c-550 psbV 0.0008
5216 Cytochrome c-550 psbV 0.0008
4925 Cytochrome c-type protein SHP shp 0.0008
4905 Cytochrome c2 Not Available 0.0008
4939 Cytochrome c2 cycA 0.0008
4964 Cytochrome c2 cycA 0.0008
4979 Cytochrome c2 cycA 0.0008
6673 Cytochrome c2 cycA 0.0008
4975 Cytochrome c-556 RPA3973 0.0008
4994 Hemoglobin-like protein HbO glbO 0.0008
4936 Cytochrome c2 iso-2 Not Available 0.0008
4984 Neuroglobin NGB 0.0008
4942 Diheme cytochrome c napB napB 0.0008
4998 Hemoglobin-like protein yjbI yjbI 0.0008
4961 Hemophore HasA hasA 0.0008
4909 CooA protein cooA 0.0008
5000 HemO hemO 0.0008
4981 Iron-starvation protein PigA pigA 0.0008
644 Heme oxygenase 2 HMOX2 0.0008
4982 Heme oxygenase 2 pbsA2 0.0008
4907 Cytochrome c-L moxG 0.0008
6865 Cytochrome c-L moxG 0.0008
291 Nitric-oxide synthase, endothelial NOS3 0.0008
4976 Apocytochrome f petA 0.0008
6407 Apocytochrome f petA 0.0008
3116 Bacterioferritin bfr 0.0008
4906 Bacterioferritin bfr 0.0008
4965 Bacterioferritin bfr 0.0008
4971 Nonaheme cytochrome c hmcA 0.0008
4910 Cytoglobin CYGB 0.0008
4904 Cytochrome c family protein GSU1996 0.0008
4937 Cytochrome oxidase subunit II rcoxA 0.0008
4935 Cytochrome c-554 cycA1 0.0008
4989 Cytochrome c551 peroxidase ccp 0.0008
5222 Cytochrome c551 peroxidase ccpA 0.0008
4999 Cytochrome P450 165B3 CYP165B3 0.0008
4926 Heme-based aerotactic transducer hemAT hemAT 0.0008
4764 Cytochrome P450 165C4 CYP165C4 0.0008
4960 Putative cytochrome P450-family protein SCO7417 0.0008
4931 Cytochrome P450 167A1 CYP167A1 0.0008
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0008
4922 Cytochrome c, putative SO_4144 0.0008
4903 Methyl-accepting chemotaxis protein Tar4 0.0008
4972 P450cin cinA 0.0008
4993 Hydroxylamine oxidoreductase hao1 0.0008
4952 Catalase/peroxidase katA 0.0008
3093 Catalase HPII katE 0.0008
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0008
4773 Deoxycytidine kinase DCK 0.0008
2599 Tyrosine-protein kinase HCK HCK 0.0007
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0007
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0007
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0007
6824 Tyrosine-protein kinase Lyn LYN 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
1517 Beta-3 adrenergic receptor ADRB3 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
2372 Bifunctional tail protein 9 0.0007
760 Fibroblast growth factor 1 FGF1 0.0007
4878 Glycoprotein hormones alpha chain CGA 0.0006
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0006
1072 Granzyme B GZMB 0.0006
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0006
4880 Membrane cofactor protein CD46 0.0006
4889 Ig epsilon chain C region IGHE 0.0006
4877 Beta-mannanase man 0.0006
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0006
4850 Beta-2-glycoprotein 1 APOH 0.0006
4856 CD209 antigen CD209 0.0006
4189 Alpha-galactosidase A GLA 0.0006
4869 Major capsid protein A430L 0.0006
757 Fusion glycoprotein F0 F 0.0006
4875 Fusion glycoprotein F0 F 0.0006
4852 Reticulon-4 receptor RTN4R 0.0006
4845 ADAM 33 ADAM33 0.0006
1354 Beta-glucuronidase GUSB 0.0006
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0006
4721 Beta-1,4-mannanase manA 0.0006
3352 Structural polyprotein Not Available 0.0006
3628 Structural polyprotein Not Available 0.0006
4892 Structural polyprotein Not Available 0.0006
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
705 Glutamate receptor 1 GRIA1 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
4920 Peroxidase/catalase katG 0.0006
828 Phenylalanine-4-hydroxylase PAH 0.0006
3109 Phenylalanine-4-hydroxylase phhA 0.0006
2119 Cytochrome b5 CYB5A 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
4990 PpcA ppcA 0.0006
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0006
793 T-cell surface antigen CD2 CD2 0.0006
4861 Interleukin-6 receptor alpha chain IL6R 0.0006
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0006
3837 Cytokine receptor common beta chain CSF2RB 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
2230 Catalase CAT 0.0005
3249 Catalase katA 0.0005
3625 Catalase katA 0.0005
4539 Catalase katA 0.0005
4941 Catalase katB 0.0005
2430 Chondroitinase B cslB 0.0005
1360 Sphingomyelin phosphodiesterase SMPD1 0.0005
76 Nitric-oxide synthase, brain NOS1 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
6151 Monocarboxylate transporter 10 SLC16A10 0.0005
2617 Nitric oxide synthase oxygenase nos 0.0005
2701 Nitric oxide synthase oxygenase nos 0.0005
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
1379 Interleukin-12 subunit beta IL12B 0.0005
4890 Hemagglutinin HA 0.0005
6566 Hemagglutinin Not Available 0.0005
3102 Flavohemoprotein hmp 0.0005
4969 Flavohemoprotein hmp 0.0005
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0005
1268 Neuropeptide S receptor NPSR1 0.0005
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0005
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0005
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0005
6858 Inactive carboxylesterase 4 CES1P1 0.0005
6133 Sodium channel subunit beta-2 SCN2B 0.0005
6134 Sodium channel subunit beta-3 SCN3B 0.0005
6129 Carbonic anhydrase-related protein 11 CA11 0.0005
6132 Sodium channel subunit beta-1 SCN1B 0.0005
6135 Sodium channel subunit beta-4 SCN4B 0.0005
6127 Carbonic anhydrase-related protein CA8 0.0005
6128 Carbonic anhydrase-related protein 10 CA10 0.0005
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0005
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0005
554 Low-density lipoprotein receptor LDLR 0.0004
852 Heparin cofactor 2 SERPIND1 0.0004
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0004
605 Fumarate reductase flavoprotein subunit frdA 0.0004
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0004
3673 Fumarate reductase flavoprotein subunit fccA 0.0004
4912 Fumarate reductase flavoprotein subunit ifcA 0.0004
6549 Fumarate reductase flavoprotein subunit frdA 0.0004
2972 6-deoxyerythronolide B hydroxylase eryF 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
6073 Potassium channel subfamily K member 9 KCNK9 0.0004
6072 Potassium channel subfamily K member 3 KCNK3 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
1859 Prostatic acid phosphatase ACPP 0.0004
595 Fibrinogen alpha chain FGA 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0004
6130 Carbonic anhydrase 13 CA13 0.0004
3140 Hemagglutinin-neuraminidase HN 0.0004
3609 Hemagglutinin-neuraminidase HN 0.0004
3444 Cyanovirin-N Not Available 0.0004
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0004
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0004
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
358 Cystathionine beta-synthase CBS 0.0004
4509 Acetoin(diacetyl) reductase budC 0.0004
958 Insulin-like growth factor 1 receptor IGF1R 0.0004
693 Hemoglobin subunit beta HBB 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
6122 Carbonic anhydrase 3 CA3 0.0004
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0004
3689 Endoglucanase A celA 0.0004
3814 Complement C1r subcomponent C1R 0.0004
3009 Beta-glucanase Not Available 0.0004
5411 Slt-IIvB stxB2e 0.0004
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0004
5563 Galectin-2 LGALS2 0.0004
1875 Pulmonary surfactant-associated protein D SFTPD 0.0004
5569 Endo-1,4-beta glucanase EngF engF 0.0004
5046 Ecotin eco 0.0004
3793 Aspartate ammonia-lyase aspA 0.0004
5554 D-galactose-binding periplasmic protein mglB 0.0004
3741 D-galactose-binding periplasmic protein precursor mglB 0.0004
5568 Endoglucanase C307 celC307 0.0004
5553 Endoglucanase E1 Acel_0614 0.0004
5562 Hexokinase Not Available 0.0004
3744 Endoglucanase SS precursor celS 0.0004
5570 Endoglucanase E-4 celD 0.0004
5559 Neopullulanase nplT 0.0004
4670 Cellulase B celB 0.0004
4668 Laminarinase TM_0024 0.0004
4667 BH0236 protein BH0236 0.0004
4671 Endoglucanase C cenC 0.0004
6268 Hydroxyacid oxidase 1 HAO1 0.0004
64 Neuraminidase NA 0.0004
641 Neuraminidase NA 0.0004
2676 Neuraminidase NA 0.0004
3026 Neuraminidase NA 0.0004
3519 Neuraminidase NA 0.0004
6007 Neuraminidase NA 0.0004
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0004
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0004
1243 Cathepsin D CTSD 0.0003
810 Heme oxygenase 1 HMOX1 0.0003
3391 Heme oxygenase 1 pbsA1 0.0003
1439 Lactotransferrin LTF 0.0003
309 Antithrombin-III SERPINC1 0.0003
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0003
896 Glutathione S-transferase Mu 1 GSTM1 0.0003
5176 YtnJ moxC 0.0003
5416 Coat protein VP1 Not Available 0.0003
2705 Dimethyl sulfoxide reductase dmsA 0.0003
2298 Cytochrome P450-cam camC 0.0003
5247 Endo-1,4-beta-xylanase Not Available 0.0003
5248 Endo-1,4-beta-xylanase xlnA 0.0003
5250 Endo-1,4-beta-xylanase xyl 0.0003
4669 Endo-1,4-beta-xylanase A xynA 0.0003
4715 Endo-1,4-beta-xylanase A xlnA 0.0003
5560 Endo-1,4-beta-xylanase A xynA 0.0003
1503 Galectin-7 LGALS7 0.0003
5498 Maltoporin lamB 0.0003
5561 Maltoporin lamB 0.0003
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0003
4622 Amylase Not Available 0.0003
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0003
6307 Ig gamma-2 chain C region IGHG2 0.0003
2826 Glucose--fructose oxidoreductase gfo 0.0003
1881 Hexokinase-1 HK1 0.0003
2581 Chondroitinase AC cslA 0.0003
6847 Lactase-phlorizin hydrolase LCT 0.0003
2324 Botulinum neurotoxin type B botB 0.0003
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0003
3747 Cellulase B precursor celB 0.0003
3547 Enterotoxin type B entB 0.0003
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0003
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0003
4819 Hydrolase Not Available 0.0003
5249 Hydrolase Not Available 0.0003
5436 Hydrolase Not Available 0.0003
2531 Alpha-amylase amyE 0.0003
2948 Alpha-amylase amy 0.0003
3169 Alpha-amylase Not Available 0.0003
2541 Neopullulanase 1 tvaI 0.0003
4811 Amylosucrase ams 0.0003
3091 Maltodextrin phosphorylase malP 0.0003
2606 Neopullulanase 2 tvaII 0.0003
4692 A/G-specific adenine glycosylase mutY 0.0003
3225 Shiga toxin B-chain stxB 0.0003
3365 Beta-amylase spoII 0.0003
4830 Aldose 1-epimerase galM 0.0003
6614 Lactase-like protein LCTL 0.0003
1675 Glucokinase GCK 0.0003
4662 Glucokinase glk 0.0003
3030 Salivary alpha-amylase AMY1A 0.0003
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0003
2508 Cyclomaltodextrin glucanotransferase cgt 0.0003
2523 Cyclomaltodextrin glucanotransferase cgt 0.0003
3207 Cyclomaltodextrin glucanotransferase amyA 0.0003
4272 POSSIBLE CELLULASE CELA1 celA1 0.0003
2570 Tetanus toxin tetX 0.0002
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0002
3668 Maltose-binding periplasmic protein precursor malE 0.0002
2802 Endoglucanase G celCCG 0.0002
2440 Endoglucanase F celCCF 0.0002
2245 Xylose isomerase xylA 0.0002
2253 Xylose isomerase xylA 0.0002
2260 Xylose isomerase xylA 0.0002
2431 Xylose isomerase xylA 0.0002
2252 Endoglucanase 5A cel5A 0.0002
10 Glycogen phosphorylase, liver form PYGL 0.0002
2723 Cholera enterotoxin subunit B ctxB 0.0002
4513 Pancreatic alpha-amylase AMY2A 0.0002
2427 Ferrichrome-iron receptor fhuA 0.0002
1152 Glycogen phosphorylase, muscle form PYGM 0.0002
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