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Biphenyl-2,3-diol 1,2-dioxygenase


Partner ID 3032
Name Biphenyl-2,3-diol 1,2-dioxygenase
Synonyms 4236
Gene name bphC
General function Amino acid transport and metabolism
Specific function Biphenyl-2,3-diol + O(2) = 2-hydroxy-6-oxo-6- phenylhexa-2,4-dienoate + H(2)O
Gene sequence + ...

ATGAGTATCGAACGTTTGGGCTACCTCGGCTTCGCCGTCAAGGATGTACCCGCCTGGGACCACTTTCTGACCAAGAGCGTGGGTTTGATGGCTGCGGGTTCGGCTGGCGACGCTGCGCTGTACCGGGCCGATCAGCGTGCCTGGCGCATCGCCGTGCAGCCGGGCGAACTCGACGACCTGGCCTACGCAGGCTTGGAAGTGGATGACGCCGCCGCGCTCGAGCGCATGGCCGACAAGCTGCGCCAGGCAGGGGTGGCCTTCACCCGCGGTGACGAAGCGCTCATGCAGCAGCGCAAGGTCATGGGCCTGCTGTGTCTGCAAGATCCGTTCGGCCTGCCGCTCGAGATTTACTACGGCCCGGCAGAAATCTTTCATGAGCCCTTCCTGCCTAGCGCCCCCGTGTCGGGCTTCGTCACGGGCGACCAGGGCATCGGGCACTTCGTGCGCTGCGTGCCCGACACGGCGAAGGCGATGGCTTTCTACACCGAGGTGCTTGGCTTTGTGCTGTCGGACATCATTGACATCCAGATGGGGCCGGAAACGAGCGTGCCCGCGCACTTTCTGCACTGCAATGGCCGTCACCACACGATCGCCCTGGCTGCTTTCCCGATCCCGAAGCGCATCCACCACTTCATGCTGCAAGCCAACACCATCGACGATGTGGGCTACGCCTTCGATCGGCTGGACGCCGCCGGGCGCATCACCTCCCTGCTCGGGCGCCACACCAACGACCAGACGCTCTCCTTCTATGCCGACACGCCGTCGCCCATGATCGAGGTCGAGTTCGGCTGGGGGCCGCGCACAGTGGATTCCTCCTGGACGGTGGCGCGACACAGCCGCACGGCCATGTGGGGTCACAAGTCGGTACGCGGCCAGCGCTGA
Protein sequence + ...

MSIERLGYLGFAVKDVPAWDHFLTKSVGLMAAGSAGDAALYRADQRAWRIAVQPGELDDLAYAGLEVDDAAALERMADKLRQAGVAFTRGDEALMQQRKVMGLLCLQDPFGLPLEIYYGPAEIFHEPFLPSAPVSGFVTGDQGIGHFVRCVPDTAKAMAFYTEVLGFVLSDIIDIQMGPETSVPAHFLHCNGRHHTIALAAFPIPKRIHHFMLQANTIDDVGYAFDRLDAAGRITSLLGRHTNDQTLSFYADTPSPMIEVEFGWGPRTVDSSWTVARHSRTAMWGHKSVRGQR
GO Classification
function
ferrous iron binding
binding
catalytic activity
ion binding
cation binding
transition metal ion binding
iron ion binding
process
cellular metabolism
aromatic compound metabolism
physiological process
metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02923 Biphenyl-2,3-Diol

Associated as Prediction

Id Name
DB00128 L-Aspartic Acid
DB00134 L-Methionine
DB00527 Dibucaine
DB00536 Guanidine
DB00622 Nicardipine
DB00623 Fluphenazine
DB00753 Isoflurane
DB00831 Trifluoperazine
DB00836 Loperamide
DB00850 Perphenazine
DB00925 Phenoxybenzamine
DB01023 Felodipine
DB01065 Melatonin
DB01069 Promethazine
DB01100 Pimozide
DB01115 Nifedipine
DB01244 Bepridil
DB01373 Calcium
DB01429 Aprindine
DB01695 N-Hydroxy-4-Phosphono-Butanamide
DB01812 Adenosine-3'-5'-Diphosphate
DB01842 3'-Phosphate-Adenosine-5'-Diphosphate
DB01925 2'-Chloro-Biphenyl-2,3-Diol
DB01942 Formic Acid
DB01961 Cytidine-3'-Monophosphate
DB02098 Adenosine-2'-5'-Diphosphate
DB02232 1,2-Dihydroxybenzene
DB02310 3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
DB02363 2'-Monophosphoadenosine-5'-Diphosphate
DB02573 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate
DB02640 Fumagillin
DB02714 3'-Uridinemonophosphate
DB02726 2-Phosphoglycolic Acid
DB02805 1-(3-O-Phosphono-Beta-L-Arabinofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB02868 3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine
DB02893 D-Methionine
DB02923 Biphenyl-2,3-Diol
DB02987 Cysteine-S-Acetamide
DB03026 Phosphoglycolohydroxamic Acid
DB03086 N'-(2s,3r)-3-Amino-4-Cyclohexyl-2-Hydroxy-Butano-N-(4-Methylphenyl)Hydrazide
DB03132 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
DB03135 [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
DB03155 1-(2-Deoxy-2-Fluoro-3-O-Phosphono-Beta-L-Ribofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB03186 U-Pi-a-Pi
DB03259 2',6'-Dichloro-Biphenyl-2,6-Diol
DB03314 Fluorotryptophane
DB03326 deoxycytidylyl-3',5'-guanosine
DB03379 2-Carboxyethylphosphonic Acid
DB03396 (E)-(2r,3r,4s,5r)-3,4,5-Trihydroxy-2-Methoxy-8,8-Dimethyl-Non-6-Enoic Acid ((3s,6r)-6-Hydroxy-2-Oxo-Azepan-3-Yl)-Amide
DB03431 Adenosine-5'-Diphosphate
DB03447 Uridylyl-2'-5'-Phospho-Adenosine
DB03448 2'-Deoxyuridine 3'-Monophosphate
DB03454 3-Methyl-Benzene-1,2-Diol
DB03512 Uridine-2',3'-Vanadate
DB03726 Purine Riboside-5'-Monophosphate
DB03765 Cytidine-2'-Monophosphate
DB03792 5-Amino-1h-Pyrimidine-2,4-Dione
DB03900 2-Methyl-2-Propanol
DB03977 N-Trimethyllysine
DB04108 (2s,3r)-3-Amino-2-Hydroxy-5-(Ethylsulfanyl)Pentanoyl-((S)-(-)-(1-Naphthyl)Ethyl)Amide
DB04120 4-Methyl-1,2-Benzenediol
DB04272 Citric Acid
DB04324 Ovalicin
DB04326 1,3-Dihydroxyacetonephosphate
DB04447 1,4-Dithiothreitol
DB04464 N-Formylmethionine
DB04510 3-Phosphoglyceric Acid
DB04513 N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
DB04514 Phosphoric Acid-2'-[2'-Deoxy-Uridine]Ester-5'-Guanosine Ester
DB04825 Prenylamine
DB04841 Flunarizine
DB07309 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID
DB07313 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
DB07322 2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
DB07323 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
DB07377 N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
DB07387 3-(BUTYLSULPHONYL)-PROPANOIC ACID
DB07478 1,1'-BIPHENYL-3,4-DIOL
DB07610 NAPHTHALENE-1,2-DIOL
DB07746 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID
DB08039 (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
DB08231 MYRISTIC ACID
DB08596 5'-deoxy-5'-piperidin-1-ylthymidine
DB08633 (CHLOROACETYL)CARBAMIC ACID (3R,4S,5S,5R)-5-METHOXY-4-[(2R,3R)-2-METHYL-3-(3-METHYL-2-BUTENYL)OXIRANYL]-1-OXASPIRO[2.5]OCT-6-YL ESTER
DB08661 1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
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