Identification
Name Temazepam
Accession Number DB00231 (APRD00676)
Type small molecule
Description A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem]
Structure
Categories (*)
Molecular Weight 300.74
Groups approved
Monoisotopic Weight 300.066555377
Pharmacology
Indication For the short-term treatment of insomnia (generally 7-10 days).
Mechanism of action Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Absorption Well absorbed, minimal first-pass metabolism.
Protein binding 96%
Biotransformation Hepatic. Temazepam is completely metabolized through conjugation prior to excretion. The major metabolite is the O-conjugate of temazepam (90%).
Route of elimination Temazepam was completely metabolized through conjugation prior to excretion; 80% to 90% of the dose appeared in the urine.
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Aminophylline Aminophylline may decrease the efficacy of Temazepam. Monitor for changes in the therapeutic effect of Temazepam if Aminophylline is initiated, discontinued or dose changed.
Clozapine The benzodiazepine, Temazepam, may increase the adverse effects of Clozapine. Monitor for respiratory depression and hypotension if concomitant therapy is initiated.
Dyphylline Dyphylline may decrease the efficacy of Temazepam. Monitor for changes in the therapeutic effect of Temazepam if Dyphylline is initiated, discontinued or dose changed.
Kava Kava may increase the effect of the benzodiazepine, temazepam.
Theophylline Theophylline may decrease the efficacy of Temazepam. Monitor for changes in the therapeutic effect of Temazepam if Theophylline is initiated, discontinued or dose changed.
Triprolidine The CNS depressants, Triprolidine and Temazepam, may increase adverse/toxic effects due to additivity. Monitor for increased CNS depressant effects during concomitant therapy.
Food Interactions
  • Avoid excessive quantities of coffee or tea (Caffeine).
  • Avoid alcohol.
  • Avoid avocado.
Gamma-aminobutyric-acid receptor subunit alpha-1
Name Gamma-aminobutyric-acid receptor subunit alpha-1
Gene Name GABRA1
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.3048
Gamma-aminobutyric-acid receptor subunit alpha-2
Name Gamma-aminobutyric-acid receptor subunit alpha-2
Gene Name GABRA2
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.2294
Gamma-aminobutyric-acid receptor subunit alpha-3
Name Gamma-aminobutyric-acid receptor subunit alpha-3
Gene Name GABRA3
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.2268
Gamma-aminobutyric-acid receptor subunit alpha-4
Name Gamma-aminobutyric-acid receptor subunit alpha-4
Gene Name GABRA4
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 0.8728
Gamma-aminobutyric-acid receptor subunit alpha-5
Name Gamma-aminobutyric-acid receptor subunit alpha-5
Gene Name GABRA5
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.2516
Gamma-aminobutyric-acid receptor subunit alpha-6
Name Gamma-aminobutyric-acid receptor subunit alpha-6
Gene Name GABRA6
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 0.8388
Gamma-aminobutyric-acid receptor subunit beta-1
Name Gamma-aminobutyric-acid receptor subunit beta-1
Gene Name GABRB1
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0942
Gamma-aminobutyric-acid receptor subunit beta-2
Name Gamma-aminobutyric-acid receptor subunit beta-2
Gene Name GABRB2
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0753
Gamma-aminobutyric-acid receptor subunit beta-3
Name Gamma-aminobutyric-acid receptor subunit beta-3
Gene Name GABRB3
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0894
Gamma-aminobutyric acid receptor subunit gamma-1
Name Gamma-aminobutyric acid receptor subunit gamma-1
Gene Name GABRG1
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0838
Gamma-aminobutyric acid receptor subunit gamma-2
Name Gamma-aminobutyric acid receptor subunit gamma-2
Gene Name GABRG2
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.1077
Gamma-aminobutyric acid receptor subunit gamma-3
Name Gamma-aminobutyric acid receptor subunit gamma-3
Gene Name GABRG3
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0563
Gamma-aminobutyric acid receptor subunit delta
Name Gamma-aminobutyric acid receptor subunit delta
Gene Name GABRD
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0724
Gamma-aminobutyric acid receptor subunit epsilon
Name Gamma-aminobutyric acid receptor subunit epsilon
Gene Name GABRE
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0705
Gamma-aminobutyric acid receptor subunit pi
Name Gamma-aminobutyric acid receptor subunit pi
Gene Name GABRP
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.047
Gamma-aminobutyric-acid receptor subunit rho-1
Name Gamma-aminobutyric-acid receptor subunit rho-1
Gene Name GABRR1
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.052
Gamma-aminobutyric acid receptor subunit rho-2
Name Gamma-aminobutyric acid receptor subunit rho-2
Gene Name GABRR2
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 1.0579
Gamma-aminobutyric acid receptor subunit rho-3
Name Gamma-aminobutyric acid receptor subunit rho-3
Gene Name GABRR3
Pharmacological action yes
Actions potentiator
References
  • Mohler H, Fritschy JM, Rudolph U: A new benzodiazepine pharmacology. J Pharmacol Exp Ther. 2002 Jan;300(1):2-8. - Pubmed
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
DTHybrid score 1.0549
Gamma-aminobutyric acid receptor subunit theta
Name Gamma-aminobutyric acid receptor subunit theta
Gene Name GABRQ
Pharmacological action yes
Actions potentiator
References
  • Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. Epub 2008 Mar 31. - Pubmed
  • Giersch A, Boucart M, Elliott M, Vidailhet P: Atypical behavioural effects of lorazepam: clues to the design of novel therapies? Pharmacol Ther. 2010 Apr;126(1):94-108. Epub 2010 Feb 4. - Pubmed
DTHybrid score 0.7058
Translocator protein
Name Translocator protein
Gene Name TSPO
Pharmacological action unknown
Actions other
References
  • Dobbin M, Martyres RF, Clode D, Champion De Crespigny FE: Association of benzodiazepine injection with the prescription of temazepam capsules. Drug Alcohol Rev. 2003 Jun;22(2):153-7. - Pubmed
  • Miller EI, Wylie FM, Oliver JS: Detection of benzodiazepines in hair using ELISA and LC-ESI-MS-MS. J Anal Toxicol. 2006 Sep;30(7):441-8. - Pubmed
  • Mant A, Whicker SD, McManus P, Birkett DJ, Edmonds D, Dumbrell D: Benzodiazepine utilisation in Australia: report from a new pharmacoepidemiological database. Aust J Public Health. 1993 Dec;17(4):345-9. - Pubmed
DTHybrid score 0.6236
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate
References
  • Application available online: - The P450 Program
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.591
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Shou M, Mei Q, Ettore MW Jr, Dai R, Baillie TA, Rushmore TH: Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives. Biochem J. 1999 Jun 15;340 ( Pt 3):845-53. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.9514
Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4427
Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4267
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.6249
Id Partner name Gene Name Score
6013 Cytochrome P450 2E1 CYP2E1 0.3426
1588 Multidrug resistance protein 1 ABCB1 0.3132
4119 Cytochrome P450 2D6 CYP2D6 0.3034
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.2967
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.2965
4118 Cytochrome P450 3A5 CYP3A5 0.2928
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.2883
4200 Cytochrome P450 1A2 CYP1A2 0.2867
921 Glutamate receptor 2 GRIA2 0.2547
6107 Cytochrome P450 3A7 CYP3A7 0.2527
587 Serum albumin ALB 0.1736
6106 Cytochrome P450 2C18 CYP2C18 0.1635
5718 Cytochrome P450 2A6 CYP2A6 0.1548
20 Prostaglandin G/H synthase 1 PTGS1 0.1497
6024 Cytochrome P450 1A1 CYP1A1 0.0949
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0767
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0693
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0663
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0617
6102 Arylamine N-acetyltransferase 2 NAT2 0.0615
6031 Cytochrome P450 3A43 CYP3A43 0.0557
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0553
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0552
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0537
6144 Solute carrier family 22 member 2 SLC22A2 0.0523
482 Glycine receptor subunit alpha-1 GLRA1 0.0516
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0516
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0495
6145 Solute carrier family 22 member 1 SLC22A1 0.0485
492 Histamine H1 receptor HRH1 0.0465
862 Multidrug resistance-associated protein 1 ABCC1 0.046
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0449
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0446
3811 Cytochrome P450 19A1 CYP19A1 0.0435
290 Prostaglandin G/H synthase 2 PTGS2 0.0433
824 Sodium-dependent serotonin transporter SLC6A4 0.0425
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0414
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0414
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0408
1898 Cytochrome P450 1B1 CYP1B1 0.0382
1729 Solute carrier family 22 member 6 SLC22A6 0.0365
461 Glycine receptor subunit alpha-3 GLRA3 0.0352
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.035
820 Glycine receptor subunit alpha-2 GLRA2 0.0311
502 5-hydroxytryptamine 2A receptor HTR2A 0.0307
136 Estrogen receptor ESR1 0.0305
468 Cytochrome P450 4A11 CYP4A11 0.0297
776 Bile salt export pump ABCB11 0.0297
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0291
731 HIV-1 protease HIV-1 protease 0.0284
556 Alpha-1A adrenergic receptor ADRA1A 0.0282
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0265
260 Cytochrome P450 51 ERG11 0.0265
761 Cytochrome P450 51 ERG11 0.0265
3163 Cytochrome P450 51 cyp51 0.0265
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0258
3937 Fatty-acid amide hydrolase FAAH 0.0258
831 D(2) dopamine receptor DRD2 0.0253
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0248
6020 Aldehyde oxidase AOX1 0.0244
6142 Solute carrier family 22 member 8 SLC22A8 0.0241
713 Sodium-dependent dopamine transporter SLC6A3 0.0239
2164 Multidrug resistance-associated protein 4 ABCC4 0.0235
318 Alpha-2A adrenergic receptor ADRA2A 0.0233
871 Glucocorticoid receptor NR3C1 0.0232
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0232
122 P2Y purinoceptor 12 P2RY12 0.0231
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0231
847 Mu-type opioid receptor OPRM1 0.0221
2981 Phospholipase A2, membrane associated PLA2G2A 0.0217
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0217
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0205
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0204
3426 Glutamine synthetase glnA 0.0201
3987 Glutamine synthetase GLUL 0.0201
467 Delta-type opioid receptor OPRD1 0.02
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0199
23 D(1A) dopamine receptor DRD1 0.0197
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0197
705 Glutamate receptor 1 GRIA1 0.0197
537 ATP synthase delta chain, mitochondrial ATP5D 0.0194
696 Kappa-type opioid receptor OPRK1 0.0193
465 Calmodulin CALM1 0.0188
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0188
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0188
891 Dihydropteroate synthase folP 0.0188
5359 Dihydropteroate synthase folP 0.0188
7175 Dihydropteroate synthase sulI 0.0188
6143 Solute carrier family 22 member 7 SLC22A7 0.0186
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0183
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0183
341 5-hydroxytryptamine 3 receptor HTR3A 0.0183
590 5-hydroxytryptamine 2C receptor HTR2C 0.0182
146 Androgen receptor AR 0.0182
3941 Amine oxidase [flavin-containing] A MAOA 0.018
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0173
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0172
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0169
118 Organic cation/carnitine transporter 2 SLC22A5 0.0166
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0164
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0164
172 Potassium channel subfamily K member 1 KCNK1 0.0164
632 Alpha-1B adrenergic receptor ADRA1B 0.0162
766 Beta-2 adrenergic receptor ADRB2 0.0159
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0159
738 Monocarboxylate transporter 1 SLC16A1 0.0156
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0153
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0151
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.0151
6182 Cytochrome P450 2J2 CYP2J2 0.015
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0149
70 Type-1 angiotensin II receptor AGTR1 0.0148
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0146
3939 Amine oxidase [flavin-containing] B MAOB 0.0144
320 5-hydroxytryptamine 1A receptor HTR1A 0.0141
489 Monocarboxylate transporter 2 SLC16A7 0.0139
6147 Solute carrier family 22 member 3 SLC22A3 0.0137
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0137
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0137
1024 Solute carrier family 22 member 11 SLC22A11 0.0135
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0134
62 Glycine receptor subunit beta GLRB 0.0132
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0129
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0128
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0125
4120 NADPH--cytochrome P450 reductase POR 0.0124
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0123
6136 Multidrug resistance-associated protein 5 ABCC5 0.0121
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0121
592 Carbonic anhydrase 4 CA4 0.012
500 Monocarboxylate transporter 4 SLC16A3 0.0118
3923 Cholinesterase BCHE 0.0118
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0117
504 Mast/stem cell growth factor receptor KIT 0.0116
789 Alpha-1D adrenergic receptor ADRA1D 0.0115
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0112
614 Progesterone receptor PGR 0.011
833 Organic cation/carnitine transporter 1 SLC22A4 0.011
6137 Multidrug resistance-associated protein 6 ABCC6 0.011
629 Alpha-2B adrenergic receptor ADRA2B 0.0107
4604 Liver carboxylesterase 1 CES1 0.0106
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0104
818 50S ribosomal protein L10 rplJ 0.0104
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0103
844 Epidermal growth factor receptor EGFR 0.0101
817 DNA topoisomerase 2-alpha TOP2A 0.0101
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.01
756 Sex hormone-binding globulin SHBG 0.01
6220 Aryl hydrocarbon receptor AHR 0.01
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.01
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0099
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0099
6141 Sodium/bile acid cotransporter SLC10A1 0.0098
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0098
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0097
4116 Dihydropteroate synthetase Not Available 0.0097
638 D(3) dopamine receptor DRD3 0.0097
869 Estrogen receptor beta ESR2 0.0097
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0097
174 Sigma 1-type opioid receptor SIGMAR1 0.0096
29 Tubulin beta-1 chain TUBB1 0.0096
49 Endothelin B receptor EDNRB 0.0096
407 Vascular endothelial growth factor receptor 2 KDR 0.0095
427 Substance-P receptor TACR1 0.0095
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0095
193 Beta-1 adrenergic receptor ADRB1 0.0093
885 5-hydroxytryptamine 1B receptor HTR1B 0.0093
1010 Cytochrome P450 51A1 CYP51A1 0.0092
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0091
578 Endothelin-1 receptor EDNRA 0.009
380 Cytochrome P450 17A1 CYP17A1 0.0089
1656 CYP2B protein CYP2B 0.0089
124 Histamine H2 receptor HRH2 0.0089
357 Carbonic anhydrase 2 CA2 0.0089
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0088
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0088
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0088
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0088
365 Dihydrofolate reductase DHFR 0.0087
2381 Dihydrofolate reductase DFR1 0.0087
2833 Dihydrofolate reductase Not Available 0.0087
2931 Dihydrofolate reductase folA 0.0087
3544 Dihydrofolate reductase folA 0.0087
3682 Dihydrofolate reductase folA 0.0087
6642 Dihydrofolate reductase folA 0.0087
6756 Dihydrofolate reductase dfrA 0.0087
161 Tubulin beta chain TUBB 0.0086
312 Tubulin beta chain TUB2 0.0086
1757 Myeloperoxidase MPO 0.0086
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0086
6148 Multidrug resistance-associated protein 7 ABCC10 0.0086
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0085
295 Carbonic anhydrase 1 CA1 0.0084
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0083
26 Vascular endothelial growth factor receptor 3 FLT4 0.0083
777 Tumor necrosis factor TNF 0.0082
6085 Fatty acid-binding protein, intestinal FABP2 0.0081
232 Corticosteroid-binding globulin SERPINA6 0.008
725 5-hydroxytryptamine 1D receptor HTR1D 0.008
32 Vascular endothelial growth factor receptor 1 FLT1 0.0079
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0079
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0079
6014 Cytochrome P450 2A13 CYP2A13 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0076
952 Dipeptidyl peptidase 4 DPP4 0.0075
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0075
1541 Metalloproteinase mmp20 0.0074
94 5-hydroxytryptamine 4 receptor HTR4 0.0073
2183 Fatty acid-binding protein, adipocyte FABP4 0.0072
228 Beta platelet-derived growth factor receptor PDGFRB 0.0072
373 Transthyretin TTR 0.0071
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0071
571 Melatonin receptor type 1A MTNR1A 0.007
362 Melatonin receptor type 1B MTNR1B 0.007
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.007
716 5-hydroxytryptamine 7 receptor HTR7 0.007
275 Arachidonate 5-lipoxygenase ALOX5 0.0068
436 5-hydroxytryptamine 2B receptor HTR2B 0.0067
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0067
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0066
856 Vitamin D3 receptor VDR 0.0066
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0066
88 Retinoic acid receptor RXR-beta RXRB 0.0065
3810 Catechol O-methyltransferase COMT 0.0063
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0063
133 Dihydropterate synthase sulI 0.0063
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0062
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0062
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0062
432 D(4) dopamine receptor DRD4 0.006
378 Alpha-2C adrenergic receptor ADRA2C 0.006
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0059
737 Mineralocorticoid receptor NR3C2 0.0059
6138 Multidrug resistance protein 3 ABCB4 0.0058
68 Cannabinoid receptor 1 CNR1 0.0058
581 Cytochrome P450 2R1 CYP2R1 0.0058
2539 Tubulin alpha-1 chain TUBA4A 0.0057
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0057
183 Vascular endothelial growth factor A VEGFA 0.0056
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0056
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0056
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0056
24 Thymidylate synthase TMP1 0.0055
359 Thymidylate synthase TYMS 0.0055
2626 Thymidylate synthase thyA 0.0055
2729 Thymidylate synthase thyA 0.0055
5352 Thymidylate synthase THYA 0.0055
1618 High affinity nerve growth factor receptor NTRK1 0.0055
5300 Antigen peptide transporter 1 TAP1 0.0055
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0054
558 Solute carrier family 12 member 1 SLC12A1 0.0054
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0053
823 Fibroblast growth factor receptor 2 FGFR2 0.0053
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0052
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0052
6126 Carbonic anhydrase 7 CA7 0.0052
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0051
3932 Glutathione S-transferase A2 GSTA2 0.0051
4203 Histamine N-methyltransferase HNMT 0.0051
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0051
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.005
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.005
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.005
518 Peroxidase/catalase T katG 0.005
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0049
84 Nuclear receptor 0B1 NR0B1 0.0049
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0049
814 Ryanodine receptor 1 RYR1 0.0048
284 DNA-directed RNA polymerase beta chain rpoB 0.0048
5773 DNA-directed RNA polymerase beta chain rpoB 0.0048
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0048
251 Alcohol dehydrogenase 1A ADH1A 0.0048
780 Retinoic acid receptor RXR-gamma RXRG 0.0047
563 Thyroid peroxidase TPO 0.0047
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0047
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0047
1648 Elastin ELN 0.0046
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0046
1992 Vitamin D-binding protein GC 0.0045
527 Prostacyclin receptor PTGIR 0.0045
1275 Estrogen sulfotransferase SULT1E1 0.0045
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0045
474 Acetylcholinesterase ACHE 0.0045
6174 50S ribosomal protein L32 rpmF 0.0045
319 Opioid receptor, sigma 1 OPRS1 0.0044
208 DNA-directed RNA polymerase beta' chain rpoC 0.0044
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0044
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0044
1196 Complement decay-accelerating factor CD55 0.0044
130 Prostacyclin synthase PTGIS 0.0044
1050 Bile salt sulfotransferase SULT2A1 0.0044
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0043
1483 Membrane copper amine oxidase AOC3 0.0043
3809 Estrogen-related receptor gamma ESRRG 0.0043
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0043
4122 Histone deacetylase 2 HDAC2 0.0042
444 Alcohol dehydrogenase 1B ADH1B 0.0042
1630 Integrin beta-2 ITGB2 0.0042
528 5-hydroxytryptamine 1E receptor HTR1E 0.0042
3947 Xanthine dehydrogenase/oxidase XDH 0.0042
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
1629 Transcription factor AP-1 JUN 0.004
634 Squalene monooxygenase SQLE 0.004
7196 Squalene monooxygenase ERG1 0.004
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.004
162 Retinoic acid receptor gamma-1 RARG 0.004
5787 Angiopoietin-1 receptor TEK 0.0039
1192 Sulfotransferase 1A1 SULT1A1 0.0039
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
2808 Chloramphenicol acetyltransferase 3 cat3 0.0038
469 Annexin A1 ANXA1 0.0038
6146 High affinity copper uptake protein 1 SLC31A1 0.0038
6043 Putative G-protein coupled receptor 44 GPR44 0.0038
165 FL cytokine receptor FLT3 0.0038
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0038
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0038
85 Growth hormone receptor GHR 0.0038
6103 Arylamine N-acetyltransferase 1 NAT1 0.0037
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0037
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0037
54 Prothrombin F2 0.0037
517 Alcohol dehydrogenase 1C ADH1C 0.0036
163 D(1B) dopamine receptor DRD5 0.0036
6432 Transporter snf 0.0036
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0036
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0036
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0036
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0036
633 Penicillin-binding proteins 1A/1B pbpA 0.0036
4311 tRNA TRDMT1 0.0036
4325 tRNA trmD 0.0036
4328 tRNA trmD 0.0036
16 Adenosine A1 receptor ADORA1 0.0036
1262 Corticotropin-lipotropin POMC 0.0035
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
3808 Dihydropteroate synthase 2 folP2 0.0035
3601 Dihydropteroate synthase 1 folP1 0.0035
3807 Dihydropteroate synthase 1 folP1 0.0035
2417 Chloramphenicol acetyltransferase cat 0.0035
3278 Chloramphenicol acetyltransferase cat 0.0035
2810 Dr hemagglutinin structural subunit draA 0.0035
1178 Adenosine A2a receptor ADORA2A 0.0035
939 50S ribosomal protein L3 rplC 0.0035
7 Nitric oxide synthase, inducible NOS2 0.0035
153 Dopamine beta-hydroxylase DBH 0.0035
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0034
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0034
239 Coagulation factor X F10 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0034
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0033
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0033
1256 5-hydroxytryptamine 6 receptor HTR6 0.0033
5880 Thrombopoietin receptor MPL 0.0033
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0032
459 Retinoic acid receptor RXR-alpha RXRA 0.0032
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0032
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0032
1268 Neuropeptide S receptor NPSR1 0.0032
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0032
5798 Mitogen-activated protein kinase 11 MAPK11 0.0032
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0032
904 Glutathione S-transferase P GSTP1 0.0032
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0032
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
267 Plasminogen activator inhibitor 1 SERPINE1 0.0031
273 Apoptosis regulator Bcl-2 BCL2 0.0031
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0031
3086 Plasmepsin-2 Not Available 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
106 Cannabinoid receptor 2 CNR2 0.003
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.003
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.003
976 Platelet glycoprotein IX GP9 0.0029
4103 Proteasome subunit beta type 2 PSMB2 0.0029
4102 Proteasome subunit beta type 5 PSMB5 0.0029
4101 Proteasome subunit beta type 1 PSMB1 0.0029
6073 Potassium channel subfamily K member 9 KCNK9 0.0029
6072 Potassium channel subfamily K member 3 KCNK3 0.0029
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0029
2207 Rhodopsin RHO 0.0029
719 Retinoic acid receptor responder protein 1 RARRES1 0.0028
770 Retinoic acid-induced protein 3 GPRC5A 0.0028
6221 Steroid hormone receptor ERR1 ESRRA 0.0028
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0028
936 Ephrin type-A receptor 2 EPHA2 0.0028
5934 Cytochrome P450 26A1 CYP26A1 0.0028
4217 Telomerase reverse transcriptase TERT 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
1852 Microtubule-associated protein 2 MAP2 0.0028
723 Cytosolic phospholipase A2 PLA2G4A 0.0027
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0027
1039 Histone deacetylase 9 HDAC9 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0027
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0027
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0027
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0027
6149 Solute carrier family 22 member 10 SLC22A10 0.0026
3856 Fibroblast growth factor receptor 3 FGFR3 0.0026
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0026
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0025
3639 Thymidine phosphorylase deoA 0.0025
3936 Thymidine phosphorylase TYMP 0.0025
164 Histamine H4 receptor HRH4 0.0025
3913 Glutamic acid decarboxylase GAD65 0.0025
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0025
6033 High affinity interleukin-8 receptor A CXCR1 0.0025
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0025
569 Retinal dehydrogenase 2 ALDH1A2 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0025
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0025
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0024
6044 Serum paraoxonase/lactonase 3 PON3 0.0024
2112 Toll-like receptor 9 TLR9 0.0024
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0024
229 Retinoic acid receptor beta RARB 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
611 Retinal dehydrogenase 1 ALDH1A1 0.0024
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
730 Retinoic acid receptor alpha RARA 0.0023
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0023
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0023
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0023
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0022
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0022
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0022
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0022
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0022
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0022
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0022
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0022
572 Integrin alpha-L ITGAL 0.0022
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0022
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0022
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0022
751 Potassium channel subfamily K member 6 KCNK6 0.0022
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0022
2320 Thymidine kinase, cytosolic TK1 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
2232 Interleukin-5 IL5 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
6506 Stathmin-4 STMN4 0.0021
735 Alanine aminotransferase 1 GPT 0.0021
3904 Alanine aminotransferase 2 GPT2 0.0021
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0021
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0021
594 Thyroxine-binding globulin SERPINA7 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
2021 Thrombomodulin THBD 0.002
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
908 Glutathione S-transferase theta-1 GSTT1 0.0019
6218 Pannexin-1 PANX1 0.0019
5923 Microtubule-associated protein tau MAPT 0.0019
5924 Microtubule-associated protein 4 MAP4 0.0019
291 Nitric-oxide synthase, endothelial NOS3 0.0019
1291 cAMP response element-binding protein CREB1 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
233 Potassium channel subfamily K member 2 KCNK2 0.0019
758 Thyroid hormone receptor alpha THRA 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0018
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
1253 Interferon gamma IFNG 0.0018
4210 Toll-like receptor 4 TLR4 0.0018
511 5-hydroxytryptamine 1F receptor HTR1F 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
6048 Troponin C, skeletal muscle TNNC2 0.0018
683 Potassium transporter GK0582 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
199 Monocarboxylate transporter 8 SLC16A2 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
268 Adenosine A2b receptor ADORA2B 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0017
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0017
896 Glutathione S-transferase Mu 1 GSTM1 0.0017
6824 Tyrosine-protein kinase Lyn LYN 0.0017
4773 Deoxycytidine kinase DCK 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
992 Protein tyrosine kinase 2 beta PTK2B 0.0017
3830 Calreticulin CALR 0.0017
346 Thyroid hormone receptor beta-1 THRB 0.0017
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0016
1517 Beta-3 adrenergic receptor ADRB3 0.0016
1360 Sphingomyelin phosphodiesterase SMPD1 0.0016
4226 Uridine phosphorylase 2 UPP2 0.0016
173 Toll-like receptor 7 TLR7 0.0016
6034 Hydroxyindole O-methyltransferase ASMT 0.0016
6035 Nuclear receptor ROR-beta RORB 0.0016
6036 Eosinophil peroxidase EPX 0.0016
3233 Bile acid receptor NR1H4 0.0015
33 Cystine/glutamate transporter SLC7A11 0.0015
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0015
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0015
4225 Uridine phosphorylase 1 UPP1 0.0015
1341 Histamine H3 receptor HRH3 0.0014
1864 RET proto-oncogene RET 0.0014
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0014
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0014
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0014
2599 Tyrosine-protein kinase HCK HCK 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
65 Matrix metalloproteinase-9 Not Available 0.0014
413 Amidophosphoribosyltransferase PPAT 0.0014
2515 Amidophosphoribosyltransferase purF 0.0014
3714 Amidophosphoribosyltransferase purF 0.0014
1792 Tissue-type plasminogen activator PLAT 0.0014
605 Fumarate reductase flavoprotein subunit frdA 0.0014
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0014
3673 Fumarate reductase flavoprotein subunit fccA 0.0014
4912 Fumarate reductase flavoprotein subunit ifcA 0.0014
6549 Fumarate reductase flavoprotein subunit frdA 0.0014
2300 Lysozyme E 0.0014
3633 Lysozyme R 0.0014
5597 Lysozyme 17 0.0014
765 Indoleamine 2,3-dioxygenase IDO1 0.0014
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0013
2216 Fibroblast growth factor receptor 4 FGFR4 0.0013
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0013
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0013
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0013
6131 Carbonic anhydrase 14 CA14 0.0013
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
4192 DNA topoisomerase 2-beta TOP2B 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
6122 Carbonic anhydrase 3 CA3 0.0012
4948 Cytochrome c-553 Not Available 0.0012
4923 Cytochrome c3 DvMF_2499 0.0012
4945 Cytochrome c3 Not Available 0.0012
4949 Cytochrome c3 DVU_3171 0.0012
4968 Cytochrome c3 cytc3 0.0012
4997 Cytochrome c3 SO_2727 0.0012
5219 Cytochrome c3 cyd 0.0012
1295 Fatty acid synthase FASN 0.0012
4902 Nine-heme cytochrome c Ddes_2038 0.0012
3189 High-molecular-weight cytochrome c hmcA 0.0012
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0012
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0012
5433 UPF0230 protein TM_1468 TM_1468 0.0012
5431 Lipid binding protein Not Available 0.0012
3616 Fatty acid-binding protein, epidermal FABP5 0.0012
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0012
6163 Copper-transporting ATPase 2 ATP7B 0.0012
6165 Copper-transporting ATPase 1 ATP7A 0.0012
3957 Adenosine deaminase ADA 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
1374 Natriuretic peptides B NPPB 0.0011
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0011
1827 Gap junction alpha-1 protein GJA1 0.0011
1908 Vascular cell adhesion protein 1 VCAM1 0.0011
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
3917 Methylenetetrahydrofolate reductase MTHFR 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.001
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.001
4386 Hemoglobin-like protein HbN glbN 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
283 SEC14-like protein 2 SEC14L2 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
2298 Cytochrome P450-cam camC 0.001
760 Fibroblast growth factor 1 FGF1 0.001
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0009
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0009
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0009
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
6168 Solute carrier family 22 member 16 SLC22A16 0.0009
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0009
2211 Fatty acid-binding protein, heart FABP3 0.0009
6459 Glycodelin PAEP 0.0009
76 Nitric-oxide synthase, brain NOS1 0.0009
3221 Cytochrome c4 cc4 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0009
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0009
828 Phenylalanine-4-hydroxylase PAH 0.0009
3109 Phenylalanine-4-hydroxylase phhA 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
6042 Prostaglandin reductase 2 PTGR2 0.0009
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0009
6677 Myelin P2 protein PMP2 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
3404 Exotoxin A eta 0.0008
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
4954 Soluble cytochrome b558 Not Available 0.0008
4925 Cytochrome c-type protein SHP shp 0.0008
4916 Cyanoglobin glbN 0.0008
4947 Bacterial hemoglobin vhb 0.0008
4915 Cytochrome c-550 psbV 0.0008
4959 Cytochrome c-550 psbV 0.0008
5216 Cytochrome c-550 psbV 0.0008
4934 Cytochrome c-551 nirM 0.0008
5218 Cytochrome c-551 nirM 0.0008
4943 Cytochrome c6 petJ 0.0008
4975 Cytochrome c-556 RPA3973 0.0008
4936 Cytochrome c2 iso-2 Not Available 0.0008
4994 Hemoglobin-like protein HbO glbO 0.0008
4905 Cytochrome c2 Not Available 0.0008
4939 Cytochrome c2 cycA 0.0008
4964 Cytochrome c2 cycA 0.0008
4979 Cytochrome c2 cycA 0.0008
6673 Cytochrome c2 cycA 0.0008
4984 Neuroglobin NGB 0.0008
4998 Hemoglobin-like protein yjbI yjbI 0.0008
3116 Bacterioferritin bfr 0.0008
4906 Bacterioferritin bfr 0.0008
4965 Bacterioferritin bfr 0.0008
5000 HemO hemO 0.0008
4910 Cytoglobin CYGB 0.0008
4909 CooA protein cooA 0.0008
4981 Iron-starvation protein PigA pigA 0.0008
4907 Cytochrome c-L moxG 0.0008
6865 Cytochrome c-L moxG 0.0008
644 Heme oxygenase 2 HMOX2 0.0008
4982 Heme oxygenase 2 pbsA2 0.0008
4942 Diheme cytochrome c napB napB 0.0008
4935 Cytochrome c-554 cycA1 0.0008
4961 Hemophore HasA hasA 0.0008
4904 Cytochrome c family protein GSU1996 0.0008
4971 Nonaheme cytochrome c hmcA 0.0008
4976 Apocytochrome f petA 0.0008
6407 Apocytochrome f petA 0.0008
4764 Cytochrome P450 165C4 CYP165C4 0.0008
4999 Cytochrome P450 165B3 CYP165B3 0.0008
4960 Putative cytochrome P450-family protein SCO7417 0.0008
4931 Cytochrome P450 167A1 CYP167A1 0.0008
4989 Cytochrome c551 peroxidase ccp 0.0008
5222 Cytochrome c551 peroxidase ccpA 0.0008
4937 Cytochrome oxidase subunit II rcoxA 0.0008
4972 P450cin cinA 0.0008
4903 Methyl-accepting chemotaxis protein Tar4 0.0008
4926 Heme-based aerotactic transducer hemAT hemAT 0.0008
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0008
4922 Cytochrome c, putative SO_4144 0.0008
4993 Hydroxylamine oxidoreductase hao1 0.0008
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0008
3093 Catalase HPII katE 0.0008
4952 Catalase/peroxidase katA 0.0008
1867 Major prion protein PRNP 0.0008
1507 Cytochrome c CYCS 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
1025 Aquaporin-1 AQP1 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
1313 Lactoylglutathione lyase GLO1 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
125 DNA polymerase beta POLB 0.0007
144 Hemoglobin subunit alpha HBA1 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
4920 Peroxidase/catalase katG 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
2119 Cytochrome b5 CYB5A 0.0006
4990 PpcA ppcA 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
2230 Catalase CAT 0.0006
3249 Catalase katA 0.0006
3625 Catalase katA 0.0006
4539 Catalase katA 0.0006
4941 Catalase katB 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
2617 Nitric oxide synthase oxygenase nos 0.0005
2701 Nitric oxide synthase oxygenase nos 0.0005
3102 Flavohemoprotein hmp 0.0005
4969 Flavohemoprotein hmp 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
3007 Carbonic anhydrase 12 CA12 0.0005
4205 Carbonic anhydrase 9 CA9 0.0005
6151 Monocarboxylate transporter 10 SLC16A10 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
1714 Mitogen-activated protein kinase 3 MAPK3 0.0005
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0005
2972 6-deoxyerythronolide B hydroxylase eryF 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
358 Cystathionine beta-synthase CBS 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
693 Hemoglobin subunit beta HBB 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
6268 Hydroxyacid oxidase 1 HAO1 0.0004
810 Heme oxygenase 1 HMOX1 0.0004
3391 Heme oxygenase 1 pbsA1 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0002