DT-Web

DB00946 - Phenprocoumon


Identification
Name Phenprocoumon
Accession Number DB00946 (APRD00228)
Type small molecule
Description Coumarin derivative that acts as a long acting oral anticoagulant. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 280.3178
Groups approved
Monoisotopic Weight 280.109944378
Pharmacology
Indication Used for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Mechanism of action Phenprocoumon inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins, this limits the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulant proteins. The synthesis of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Depression of three of the four vitamin K-dependent coagulation factors (factors II, VII, and X) results in decreased prothrombin levels and a decrease in the amount of thrombin generated and bound to fibrin. This reduces the thrombogenicity of clots.
Absorption Bioavailability is close to 100%
Protein binding 99%
Biotransformation Phenprocoumon is stereoselectively metabolized by hepatic microsomal enzymes (cytochrome P-450) to inactive hydroxylated metabolites (predominant route) and by reductases to reduced metabolites. Cytochrome P450 2C9 is the principal form of human liver P-450 responsible for metabolism.
Route of elimination Not Available
Toxicity 50=500 mg/kg. Symptoms of overdose includes suspected or overt abnormal bleeding (e.g., appearance of blood in stools or urine, hematuria, excessive menstrual bleeding, melena, petechiae, excessive bruising or persistent oozing from superficial injuries).
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Vitamin K epoxide reductase complex subunit 1
Name Vitamin K epoxide reductase complex subunit 1
Gene Name VKORC1
Pharmacological action yes
Actions inhibitor
References
  • Schalekamp T, Brasse BP, Roijers JF, van Meegen E, van der Meer FJ, van Wijk EM, Egberts AC, de Boer A: VKORC1 and CYP2C9 genotypes and phenprocoumon anticoagulation status: interaction between both genotypes affects dose requirement. Clin Pharmacol Ther. 2007 Feb;81(2):185-93. Epub 2006 Dec 27. - Pubmed
  • Reitsma PH, van der Heijden JF, Groot AP, Rosendaal FR, Buller HR: A C1173T dimorphism in the VKORC1 gene determines coumarin sensitivity and bleeding risk. PLoS Med. 2005 Oct;2(10):e312. Epub 2005 Oct 11. - Pubmed
  • Thijssen HH, Baars LG: Microsomal warfarin binding and vitamin K 2,3-epoxide reductase. Biochem Pharmacol. 1989 Apr 1;38(7):1115-20. - Pubmed
  • Thijssen HH, Baars LG, Vervoort-Peters HT: Vitamin K 2,3-epoxide reductase: the basis for stereoselectivity of 4-hydroxycoumarin anticoagulant activity. Br J Pharmacol. 1988 Nov;95(3):675-82. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.5047

Enzymes


Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3011
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Schalekamp T, Brasse BP, Roijers JF, van Meegen E, van der Meer FJ, van Wijk EM, Egberts AC, de Boer A: VKORC1 and CYP2C9 genotypes and phenprocoumon anticoagulation status: interaction between both genotypes affects dose requirement. Clin Pharmacol Ther. 2007 Feb;81(2):185-93. Epub 2006 Dec 27. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.423
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4944

Carriers


Predictions


Id Partner name Gene Name Score
6016 Cytochrome P450 2C19 CYP2C19 0.2267
4119 Cytochrome P450 2D6 CYP2D6 0.2082
1588 Multidrug resistance protein 1 ABCB1 0.1819
4200 Cytochrome P450 1A2 CYP1A2 0.1808
4118 Cytochrome P450 3A5 CYP3A5 0.1376
6030 Cytochrome P450 2B6 CYP2B6 0.1065
6107 Cytochrome P450 3A7 CYP3A7 0.0955
6013 Cytochrome P450 2E1 CYP2E1 0.0923
20 Prostaglandin G/H synthase 1 PTGS1 0.0878
6024 Cytochrome P450 1A1 CYP1A1 0.078
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.07
2159 Quinone oxidoreductase CRYZ 0.0653
5718 Cytochrome P450 2A6 CYP2A6 0.0623
290 Prostaglandin G/H synthase 2 PTGS2 0.0562
6106 Cytochrome P450 2C18 CYP2C18 0.0559
1729 Solute carrier family 22 member 6 SLC22A6 0.0522
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0488
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0476
220 Sodium channel protein type 5 subunit alpha SCN5A 0.047
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0456
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.043
862 Multidrug resistance-associated protein 1 ABCC1 0.0423
556 Alpha-1A adrenergic receptor ADRA1A 0.0373
492 Histamine H1 receptor HRH1 0.037
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0363
891 Dihydropteroate synthase folP 0.0353
5359 Dihydropteroate synthase folP 0.0353
7175 Dihydropteroate synthase sulI 0.0353
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0353
824 Sodium-dependent serotonin transporter SLC6A4 0.0344
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.034
6145 Solute carrier family 22 member 1 SLC22A1 0.032
502 5-hydroxytryptamine 2A receptor HTR2A 0.0317
6142 Solute carrier family 22 member 8 SLC22A8 0.0313
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0307
2164 Multidrug resistance-associated protein 4 ABCC4 0.0306
320 5-hydroxytryptamine 1A receptor HTR1A 0.0297
3811 Cytochrome P450 19A1 CYP19A1 0.0268
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0264
136 Estrogen receptor ESR1 0.0264
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.026
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0257
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0256
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0255
632 Alpha-1B adrenergic receptor ADRA1B 0.0251
1898 Cytochrome P450 1B1 CYP1B1 0.0245
831 D(2) dopamine receptor DRD2 0.0242
6144 Solute carrier family 22 member 2 SLC22A2 0.0241
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0237
789 Alpha-1D adrenergic receptor ADRA1D 0.0233
1024 Solute carrier family 22 member 11 SLC22A11 0.0232
871 Glucocorticoid receptor NR3C1 0.023
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0227
847 Mu-type opioid receptor OPRM1 0.0223
6143 Solute carrier family 22 member 7 SLC22A7 0.022
844 Epidermal growth factor receptor EGFR 0.0215
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.021
318 Alpha-2A adrenergic receptor ADRA2A 0.0201
776 Bile salt export pump ABCB11 0.0199
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0198
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0197
696 Kappa-type opioid receptor OPRK1 0.0193
23 D(1A) dopamine receptor DRD1 0.0192
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0192
731 HIV-1 protease HIV-1 protease 0.0189
766 Beta-2 adrenergic receptor ADRB2 0.0189
238 Peroxisome proliferator-activated receptor gamma PPARG 0.018
713 Sodium-dependent dopamine transporter SLC6A3 0.0174
465 Calmodulin CALM1 0.0172
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0172
467 Delta-type opioid receptor OPRD1 0.0171
1389 Transforming growth factor beta-1 TGFB1 0.0169
118 Organic cation/carnitine transporter 2 SLC22A5 0.0164
590 5-hydroxytryptamine 2C receptor HTR2C 0.0163
70 Type-1 angiotensin II receptor AGTR1 0.0162
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.016
122 P2Y purinoceptor 12 P2RY12 0.016
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0159
400 Coagulation factor IX F9 0.0153
5461 Coagulation factor IX F9 0.0153
193 Beta-1 adrenergic receptor ADRB1 0.0153
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0151
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.015
604 Vitamin K-dependent protein Z PROZ 0.015
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0147
3941 Amine oxidase [flavin-containing] A MAOA 0.0144
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0144
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0143
6541 Peptostreptococcal albumin-binding protein pab 0.0142
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0142
341 5-hydroxytryptamine 3 receptor HTR3A 0.0142
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0141
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0141
6141 Sodium/bile acid cotransporter SLC10A1 0.0138
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0137
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0135
6147 Solute carrier family 22 member 3 SLC22A3 0.0135
146 Androgen receptor AR 0.0133
380 Cytochrome P450 17A1 CYP17A1 0.013
6020 Aldehyde oxidase AOX1 0.0129
260 Cytochrome P450 51 ERG11 0.0129
761 Cytochrome P450 51 ERG11 0.0129
3163 Cytochrome P450 51 cyp51 0.0129
183 Vascular endothelial growth factor A VEGFA 0.0128
422 Vitamin K-dependent protein C PROC 0.0127
1245 Vitamin K-dependent protein S PROS1 0.0126
811 Translocator protein TSPO 0.0124
6031 Cytochrome P450 3A43 CYP3A43 0.0123
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0121
3939 Amine oxidase [flavin-containing] B MAOB 0.012
756 Sex hormone-binding globulin SHBG 0.012
2183 Fatty acid-binding protein, adipocyte FABP4 0.0119
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0118
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0117
1050 Bile salt sulfotransferase SULT2A1 0.0116
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0116
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0114
3923 Cholinesterase BCHE 0.0114
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0112
614 Progesterone receptor PGR 0.0111
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0111
468 Cytochrome P450 4A11 CYP4A11 0.011
6085 Fatty acid-binding protein, intestinal FABP2 0.0109
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0108
2211 Fatty acid-binding protein, heart FABP3 0.0108
6102 Arylamine N-acetyltransferase 2 NAT2 0.0106
3917 Methylenetetrahydrofolate reductase MTHFR 0.0106
6182 Cytochrome P450 2J2 CYP2J2 0.0106
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0106
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0106
4604 Liver carboxylesterase 1 CES1 0.0106
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0104
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0103
1757 Myeloperoxidase MPO 0.0102
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0102
3947 Xanthine dehydrogenase/oxidase XDH 0.0101
1517 Beta-3 adrenergic receptor ADRB3 0.0101
738 Monocarboxylate transporter 1 SLC16A1 0.0101
833 Organic cation/carnitine transporter 1 SLC22A4 0.0101
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.01
798 Osteocalcin BGLAP 0.01
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0099
885 5-hydroxytryptamine 1B receptor HTR1B 0.0098
4116 Dihydropteroate synthetase Not Available 0.0097
504 Mast/stem cell growth factor receptor KIT 0.0097
482 Glycine receptor subunit alpha-1 GLRA1 0.0096
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0096
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0095
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0095
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0095
566 Serotransferrin TF 0.0094
5787 Angiopoietin-1 receptor TEK 0.0093
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0092
6136 Multidrug resistance-associated protein 5 ABCC5 0.0092
705 Glutamate receptor 1 GRIA1 0.0091
239 Coagulation factor X F10 0.0091
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0091
54 Prothrombin F2 0.009
373 Transthyretin TTR 0.009
629 Alpha-2B adrenergic receptor ADRA2B 0.0089
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0088
369 Coagulation factor VII F7 0.0088
768 FK506-binding protein 1A FKBP1A 0.0088
869 Estrogen receptor beta ESR2 0.0087
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0086
1656 CYP2B protein CYP2B 0.0084
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0084
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0082
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0082
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0082
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0082
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0082
537 ATP synthase delta chain, mitochondrial ATP5D 0.0082
29 Tubulin beta-1 chain TUBB1 0.0081
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0081
365 Dihydrofolate reductase DHFR 0.0081
2381 Dihydrofolate reductase DFR1 0.0081
2833 Dihydrofolate reductase Not Available 0.0081
2931 Dihydrofolate reductase folA 0.0081
3544 Dihydrofolate reductase folA 0.0081
3682 Dihydrofolate reductase folA 0.0081
6642 Dihydrofolate reductase folA 0.0081
6756 Dihydrofolate reductase dfrA 0.0081
232 Corticosteroid-binding globulin SERPINA6 0.008
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.008
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.008
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0079
645 Penicillin-binding protein 1A mrcA 0.0078
5805 Penicillin-binding protein 1A ponA 0.0078
6185 Penicillin-binding protein 1A mrcA 0.0078
6799 Penicillin-binding protein 1A pbpA 0.0078
378 Alpha-2C adrenergic receptor ADRA2C 0.0078
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0077
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0077
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0077
558 Solute carrier family 12 member 1 SLC12A1 0.0076
6137 Multidrug resistance-associated protein 6 ABCC6 0.0076
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0076
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0075
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0075
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0075
1618 High affinity nerve growth factor receptor NTRK1 0.0075
638 D(3) dopamine receptor DRD3 0.0075
1541 Metalloproteinase mmp20 0.0074
88 Retinoic acid receptor RXR-beta RXRB 0.0073
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0073
543 Penicillin-binding protein 1B mrcB 0.0072
6186 Penicillin-binding protein 1B ponB 0.0072
6822 Penicillin-binding protein 1b pbp1b 0.0072
6844 Penicillin-binding protein 1b pbp1b 0.0072
436 5-hydroxytryptamine 2B receptor HTR2B 0.0072
725 5-hydroxytryptamine 1D receptor HTR1D 0.0072
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0072
1 Peptidoglycan synthetase ftsI ftsI 0.0071
4155 Peptidoglycan synthetase ftsI ftsI 0.0071
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0071
6148 Multidrug resistance-associated protein 7 ABCC10 0.007
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0069
49 Endothelin B receptor EDNRB 0.0069
228 Beta platelet-derived growth factor receptor PDGFRB 0.0069
2853 14 kDa fatty acid-binding protein Not Available 0.0068
817 DNA topoisomerase 2-alpha TOP2A 0.0068
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0068
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0068
295 Carbonic anhydrase 1 CA1 0.0068
952 Dipeptidyl peptidase 4 DPP4 0.0067
407 Vascular endothelial growth factor receptor 2 KDR 0.0067
592 Carbonic anhydrase 4 CA4 0.0067
24 Thymidylate synthase TMP1 0.0066
359 Thymidylate synthase TYMS 0.0066
2626 Thymidylate synthase thyA 0.0066
2729 Thymidylate synthase thyA 0.0066
5352 Thymidylate synthase THYA 0.0066
36 Insulin receptor INSR 0.0066
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0065
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0065
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0065
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0065
578 Endothelin-1 receptor EDNRA 0.0065
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0065
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0065
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0065
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0064
275 Arachidonate 5-lipoxygenase ALOX5 0.0064
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0063
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0063
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0063
133 Dihydropterate synthase sulI 0.0063
459 Retinoic acid receptor RXR-alpha RXRA 0.0062
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0062
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0062
3932 Glutathione S-transferase A2 GSTA2 0.0061
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0061
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.006
357 Carbonic anhydrase 2 CA2 0.006
6103 Arylamine N-acetyltransferase 1 NAT1 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0059
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0059
6043 Putative G-protein coupled receptor 44 GPR44 0.0058
3810 Catechol O-methyltransferase COMT 0.0058
818 50S ribosomal protein L10 rplJ 0.0058
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0058
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0058
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0057
432 D(4) dopamine receptor DRD4 0.0057
780 Retinoic acid receptor RXR-gamma RXRG 0.0056
427 Substance-P receptor TACR1 0.0056
777 Tumor necrosis factor TNF 0.0056
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0056
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0055
716 5-hydroxytryptamine 7 receptor HTR7 0.0055
4120 NADPH--cytochrome P450 reductase POR 0.0055
737 Mineralocorticoid receptor NR3C2 0.0054
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0054
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0053
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0053
94 5-hydroxytryptamine 4 receptor HTR4 0.0053
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0053
594 Thyroxine-binding globulin SERPINA7 0.0053
6014 Cytochrome P450 2A13 CYP2A13 0.0052
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0052
161 Tubulin beta chain TUBB 0.0052
312 Tubulin beta chain TUB2 0.0052
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0052
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0052
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0051
4203 Histamine N-methyltransferase HNMT 0.0051
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0051
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.005
6432 Transporter snf 0.005
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0049
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0049
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0049
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0049
758 Thyroid hormone receptor alpha THRA 0.0049
1010 Cytochrome P450 51A1 CYP51A1 0.0049
856 Vitamin D3 receptor VDR 0.0049
814 Ryanodine receptor 1 RYR1 0.0048
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0048
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0048
162 Retinoic acid receptor gamma-1 RARG 0.0048
6220 Aryl hydrocarbon receptor AHR 0.0047
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0047
124 Histamine H2 receptor HRH2 0.0047
1648 Elastin ELN 0.0046
3382 Glycolipid transfer protein GLTP 0.0046
68 Cannabinoid receptor 1 CNR1 0.0046
26 Vascular endothelial growth factor receptor 3 FLT4 0.0046
527 Prostacyclin receptor PTGIR 0.0045
1275 Estrogen sulfotransferase SULT1E1 0.0045
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0045
474 Acetylcholinesterase ACHE 0.0045
115 Penicillin-binding protein 2 mrdA 0.0044
6069 Penicillin-binding protein 2 mrdA 0.0044
6118 Penicillin-binding protein 2 penA 0.0044
6187 Penicillin-binding protein 2 pbpA 0.0044
6686 Penicillin-binding protein 2 pbp2 0.0044
6939 Penicillin-binding protein 2 mrdA 0.0044
7163 Penicillin-binding protein 2 pbpA 0.0044
208 DNA-directed RNA polymerase beta' chain rpoC 0.0044
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0044
130 Prostacyclin synthase PTGIS 0.0044
32 Vascular endothelial growth factor receptor 1 FLT1 0.0044
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0044
2178 Metabotropic glutamate receptor 5 GRM5 0.0044
346 Thyroid hormone receptor beta-1 THRB 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
887 DNA gyrase subunit B gyrB 0.0044
4150 DNA gyrase subunit B gyrB 0.0044
6225 DNA gyrase subunit B gyrB 0.0044
6033 High affinity interleukin-8 receptor A CXCR1 0.0044
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0043
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0043
633 Penicillin-binding proteins 1A/1B pbpA 0.0043
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0043
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0042
1992 Vitamin D-binding protein GC 0.0042
6149 Solute carrier family 22 member 10 SLC22A10 0.0042
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0041
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0041
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0041
528 5-hydroxytryptamine 1E receptor HTR1E 0.0041
6677 Myelin P2 protein PMP2 0.0041
229 Retinoic acid receptor beta RARB 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
1629 Transcription factor AP-1 JUN 0.004
1864 RET proto-oncogene RET 0.004
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.004
4161 Furin FURIN 0.004
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.004
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.004
730 Retinoic acid receptor alpha RARA 0.004
921 Glutamate receptor 2 GRIA2 0.004
1256 5-hydroxytryptamine 6 receptor HTR6 0.004
163 D(1B) dopamine receptor DRD5 0.0039
4210 Toll-like receptor 4 TLR4 0.0039
6138 Multidrug resistance protein 3 ABCB4 0.0039
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
6067 Penicillin binding protein 2a mecA 0.0038
571 Melatonin receptor type 1A MTNR1A 0.0038
362 Melatonin receptor type 1B MTNR1B 0.0038
6126 Carbonic anhydrase 7 CA7 0.0038
284 DNA-directed RNA polymerase beta chain rpoB 0.0037
5773 DNA-directed RNA polymerase beta chain rpoB 0.0037
518 Peroxidase/catalase T katG 0.0037
4122 Histone deacetylase 2 HDAC2 0.0037
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0036
1291 cAMP response element-binding protein CREB1 0.0036
199 Monocarboxylate transporter 8 SLC16A2 0.0036
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0036
819 Penicillin-binding protein 4 dacB 0.0036
16 Adenosine A1 receptor ADORA1 0.0036
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0036
4237 50S ribosomal protein L22 rplV 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
2539 Tubulin alpha-1 chain TUBA4A 0.0035
1178 Adenosine A2a receptor ADORA2A 0.0035
939 50S ribosomal protein L3 rplC 0.0035
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0035
322 Vasopressin V2 receptor AVPR2 0.0034
1483 Membrane copper amine oxidase AOC3 0.0034
5300 Antigen peptide transporter 1 TAP1 0.0034
751 Potassium channel subfamily K member 6 KCNK6 0.0034
3639 Thymidine phosphorylase deoA 0.0034
3936 Thymidine phosphorylase TYMP 0.0034
581 Cytochrome P450 2R1 CYP2R1 0.0034
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0033
273 Apoptosis regulator Bcl-2 BCL2 0.0033
2981 Phospholipase A2, membrane associated PLA2G2A 0.0033
5880 Thrombopoietin receptor MPL 0.0033
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0033
1867 Major prion protein PRNP 0.0032
5934 Cytochrome P450 26A1 CYP26A1 0.0032
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0032
6174 50S ribosomal protein L32 rpmF 0.0032
4217 Telomerase reverse transcriptase TERT 0.0032
595 Fibrinogen alpha chain FGA 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0031
1196 Complement decay-accelerating factor CD55 0.0031
3809 Estrogen-related receptor gamma ESRRG 0.0031
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0031
172 Potassium channel subfamily K member 1 KCNK1 0.0031
3086 Plasmepsin-2 Not Available 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
3760 Penicillin-binding protein 5 precursor dacA 0.0031
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
823 Fibroblast growth factor receptor 2 FGFR2 0.003
904 Glutathione S-transferase P GSTP1 0.0029
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0029
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
153 Dopamine beta-hydroxylase DBH 0.0029
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0029
2207 Rhodopsin RHO 0.0028
634 Squalene monooxygenase SQLE 0.0028
7196 Squalene monooxygenase ERG1 0.0028
233 Potassium channel subfamily K member 2 KCNK2 0.0028
6207 30S ribosomal protein S14 rpsN 0.0028
6209 30S ribosomal protein S19 rpsS 0.0028
6712 30S ribosomal protein S19 rpsS 0.0028
6726 30S ribosomal protein S19 rpsS 0.0028
4226 Uridine phosphorylase 2 UPP2 0.0028
1525 Heparin-binding growth factor 2 FGF2 0.0028
5431 Lipid binding protein Not Available 0.0028
3616 Fatty acid-binding protein, epidermal FABP5 0.0028
5433 UPF0230 protein TM_1468 TM_1468 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
1852 Microtubule-associated protein 2 MAP2 0.0028
723 Cytosolic phospholipase A2 PLA2G4A 0.0027
2808 Chloramphenicol acetyltransferase 3 cat3 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
84 Nuclear receptor 0B1 NR0B1 0.0027
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0027
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0027
1192 Sulfotransferase 1A1 SULT1A1 0.0027
469 Annexin A1 ANXA1 0.0027
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0027
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0027
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0026
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0026
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0026
4225 Uridine phosphorylase 1 UPP1 0.0026
3856 Fibroblast growth factor receptor 3 FGFR3 0.0026
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0026
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0025
165 FL cytokine receptor FLT3 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
2320 Thymidine kinase, cytosolic TK1 0.0025
2417 Chloramphenicol acetyltransferase cat 0.0025
3278 Chloramphenicol acetyltransferase cat 0.0025
3808 Dihydropteroate synthase 2 folP2 0.0025
3601 Dihydropteroate synthase 1 folP1 0.0025
3807 Dihydropteroate synthase 1 folP1 0.0025
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0025
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0025
2810 Dr hemagglutinin structural subunit draA 0.0025
3426 Glutamine synthetase glnA 0.0025
3987 Glutamine synthetase GLUL 0.0025
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0025
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0025
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0024
3937 Fatty-acid amide hydrolase FAAH 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
413 Amidophosphoribosyltransferase PPAT 0.0024
2515 Amidophosphoribosyltransferase purF 0.0024
3714 Amidophosphoribosyltransferase purF 0.0024
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
2112 Toll-like receptor 9 TLR9 0.0024
6231 Pepsin A PGA3 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0023
283 SEC14-like protein 2 SEC14L2 0.0023
332 Beta-lactamase blaZ 0.0023
2478 Beta-lactamase ampC 0.0023
2613 Beta-lactamase ampC 0.0023
2635 Beta-lactamase ampC 0.0023
2700 Beta-lactamase penP 0.0023
5445 Beta-lactamase blaB 0.0023
6019 Beta-lactamase SHV-7 0.0023
6701 Beta-lactamase cphA 0.0023
2021 Thrombomodulin THBD 0.0023
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0023
6146 High affinity copper uptake protein 1 SLC31A1 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0022
1360 Sphingomyelin phosphodiesterase SMPD1 0.0022
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0022
4311 tRNA TRDMT1 0.0022
4325 tRNA trmD 0.0022
4328 tRNA trmD 0.0022
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0022
6459 Glycodelin PAEP 0.0022
6218 Pannexin-1 PANX1 0.0022
164 Histamine H4 receptor HRH4 0.0022
1714 Mitogen-activated protein kinase 3 MAPK3 0.0022
319 Opioid receptor, sigma 1 OPRS1 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0022
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
2232 Interleukin-5 IL5 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
6506 Stathmin-4 STMN4 0.0021
707 72 kDa type IV collagenase MMP2 0.0021
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
244 Angiotensin-converting enzyme ACE 0.0021
976 Platelet glycoprotein IX GP9 0.0021
1630 Integrin beta-2 ITGB2 0.0021
4103 Proteasome subunit beta type 2 PSMB2 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
4102 Proteasome subunit beta type 5 PSMB5 0.0021
4101 Proteasome subunit beta type 1 PSMB1 0.0021
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0021
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
6501 Fatty acid-binding protein, liver FABP1 0.002
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.002
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.002
489 Monocarboxylate transporter 2 SLC16A7 0.002
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.002
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.002
5923 Microtubule-associated protein tau MAPT 0.0019
5924 Microtubule-associated protein 4 MAP4 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
33 Cystine/glutamate transporter SLC7A11 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
65 Matrix metalloproteinase-9 Not Available 0.0018
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0018
174 Sigma 1-type opioid receptor SIGMAR1 0.0018
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
6151 Monocarboxylate transporter 10 SLC16A10 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
1262 Corticotropin-lipotropin POMC 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
712 Tubulin alpha chain TUB1 0.0018
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
6048 Troponin C, skeletal muscle TNNC2 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
683 Potassium transporter GK0582 0.0018
1198 Serum paraoxonase/arylesterase 1 PON1 0.0018
6223 Penicillin-binding protein 1C pbpC 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0017
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
719 Retinoic acid receptor responder protein 1 RARRES1 0.0017
770 Retinoic acid-induced protein 3 GPRC5A 0.0017
268 Adenosine A2b receptor ADORA2B 0.0017
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0017
106 Cannabinoid receptor 2 CNR2 0.0017
6044 Serum paraoxonase/lactonase 3 PON3 0.0017
6824 Tyrosine-protein kinase Lyn LYN 0.0017
4773 Deoxycytidine kinase DCK 0.0017
992 Protein tyrosine kinase 2 beta PTK2B 0.0017
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0016
1268 Neuropeptide S receptor NPSR1 0.0016
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0016
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0016
1792 Tissue-type plasminogen activator PLAT 0.0016
563 Thyroid peroxidase TPO 0.0016
572 Integrin alpha-L ITGAL 0.0016
173 Toll-like receptor 7 TLR7 0.0016
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0016
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0016
5798 Mitogen-activated protein kinase 11 MAPK11 0.0016
3913 Glutamic acid decarboxylase GAD65 0.0016
3233 Bile acid receptor NR1H4 0.0015
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0015
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0015
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0015
936 Ephrin type-A receptor 2 EPHA2 0.0015
569 Retinal dehydrogenase 2 ALDH1A2 0.0015
267 Plasminogen activator inhibitor 1 SERPINE1 0.0015
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0015
7 Nitric oxide synthase, inducible NOS2 0.0015
6073 Potassium channel subfamily K member 9 KCNK9 0.0015
6072 Potassium channel subfamily K member 3 KCNK3 0.0015
1341 Histamine H3 receptor HRH3 0.0014
611 Retinal dehydrogenase 1 ALDH1A1 0.0014
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0014
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0014
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0014
2599 Tyrosine-protein kinase HCK HCK 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0014
6221 Steroid hormone receptor ERR1 ESRRA 0.0014
605 Fumarate reductase flavoprotein subunit frdA 0.0014
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0014
3673 Fumarate reductase flavoprotein subunit fccA 0.0014
4912 Fumarate reductase flavoprotein subunit ifcA 0.0014
6549 Fumarate reductase flavoprotein subunit frdA 0.0014
1039 Histone deacetylase 9 HDAC9 0.0013
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0013
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0013
2216 Fibroblast growth factor receptor 4 FGFR4 0.0013
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0013
735 Alanine aminotransferase 1 GPT 0.0013
3904 Alanine aminotransferase 2 GPT2 0.0013
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0013
908 Glutathione S-transferase theta-1 GSTT1 0.0013
1405 Thiopurine S-methyltransferase TPMT 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
4192 DNA topoisomerase 2-beta TOP2B 0.0012
822 Aldose reductase AKR1B1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0012
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0012
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0012
1295 Fatty acid synthase FASN 0.0012
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0012
4948 Cytochrome c-553 Not Available 0.0012
4923 Cytochrome c3 DvMF_2499 0.0012
4945 Cytochrome c3 Not Available 0.0012
4949 Cytochrome c3 DVU_3171 0.0012
4968 Cytochrome c3 cytc3 0.0012
4997 Cytochrome c3 SO_2727 0.0012
5219 Cytochrome c3 cyd 0.0012
4902 Nine-heme cytochrome c Ddes_2038 0.0012
3189 High-molecular-weight cytochrome c hmcA 0.0012
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0012
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0012
6042 Prostaglandin reductase 2 PTGR2 0.0011
3957 Adenosine deaminase ADA 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0011
1374 Natriuretic peptides B NPPB 0.0011
1827 Gap junction alpha-1 protein GJA1 0.0011
1908 Vascular cell adhesion protein 1 VCAM1 0.0011
896 Glutathione S-transferase Mu 1 GSTM1 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.001
5756 D-alanyl-D-alanine carboxypeptidase dac 0.001
5251 Carbonyl reductase [NADPH] 1 CBR1 0.001
511 5-hydroxytryptamine 1F receptor HTR1F 0.001
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.001
4386 Hemoglobin-like protein HbN glbN 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
251 Alcohol dehydrogenase 1A ADH1A 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
2298 Cytochrome P450-cam camC 0.001
760 Fibroblast growth factor 1 FGF1 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
820 Glycine receptor subunit alpha-2 GLRA2 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0009
3221 Cytochrome c4 cc4 0.0009
828 Phenylalanine-4-hydroxylase PAH 0.0009
3109 Phenylalanine-4-hydroxylase phhA 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
6131 Carbonic anhydrase 14 CA14 0.0009
1313 Lactoylglutathione lyase GLO1 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
444 Alcohol dehydrogenase 1B ADH1B 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
2132 Protein S100-B S100B 0.0009
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
3404 Exotoxin A eta 0.0008
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
6122 Carbonic anhydrase 3 CA3 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0008
4954 Soluble cytochrome b558 Not Available 0.0008
4943 Cytochrome c6 petJ 0.0008
4916 Cyanoglobin glbN 0.0008
4947 Bacterial hemoglobin vhb 0.0008
4934 Cytochrome c-551 nirM 0.0008
5218 Cytochrome c-551 nirM 0.0008
4915 Cytochrome c-550 psbV 0.0008
4959 Cytochrome c-550 psbV 0.0008
5216 Cytochrome c-550 psbV 0.0008
4925 Cytochrome c-type protein SHP shp 0.0008
5000 HemO hemO 0.0008
4975 Cytochrome c-556 RPA3973 0.0008
4936 Cytochrome c2 iso-2 Not Available 0.0008
4994 Hemoglobin-like protein HbO glbO 0.0008
4905 Cytochrome c2 Not Available 0.0008
4939 Cytochrome c2 cycA 0.0008
4964 Cytochrome c2 cycA 0.0008
4979 Cytochrome c2 cycA 0.0008
6673 Cytochrome c2 cycA 0.0008
4942 Diheme cytochrome c napB napB 0.0008
4984 Neuroglobin NGB 0.0008
4981 Iron-starvation protein PigA pigA 0.0008
4998 Hemoglobin-like protein yjbI yjbI 0.0008
4935 Cytochrome c-554 cycA1 0.0008
4909 CooA protein cooA 0.0008
4910 Cytoglobin CYGB 0.0008
4961 Hemophore HasA hasA 0.0008
3116 Bacterioferritin bfr 0.0008
4906 Bacterioferritin bfr 0.0008
4965 Bacterioferritin bfr 0.0008
4904 Cytochrome c family protein GSU1996 0.0008
644 Heme oxygenase 2 HMOX2 0.0008
4982 Heme oxygenase 2 pbsA2 0.0008
4971 Nonaheme cytochrome c hmcA 0.0008
4907 Cytochrome c-L moxG 0.0008
6865 Cytochrome c-L moxG 0.0008
4937 Cytochrome oxidase subunit II rcoxA 0.0008
4989 Cytochrome c551 peroxidase ccp 0.0008
5222 Cytochrome c551 peroxidase ccpA 0.0008
4931 Cytochrome P450 167A1 CYP167A1 0.0008
4976 Apocytochrome f petA 0.0008
6407 Apocytochrome f petA 0.0008
4764 Cytochrome P450 165C4 CYP165C4 0.0008
4999 Cytochrome P450 165B3 CYP165B3 0.0008
4960 Putative cytochrome P450-family protein SCO7417 0.0008
4903 Methyl-accepting chemotaxis protein Tar4 0.0008
4922 Cytochrome c, putative SO_4144 0.0008
4926 Heme-based aerotactic transducer hemAT hemAT 0.0008
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0008
4972 P450cin cinA 0.0008
4993 Hydroxylamine oxidoreductase hao1 0.0008
4952 Catalase/peroxidase katA 0.0008
3093 Catalase HPII katE 0.0008
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
1507 Cytochrome c CYCS 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0008
291 Nitric-oxide synthase, endothelial NOS3 0.0008
1025 Aquaporin-1 AQP1 0.0008
517 Alcohol dehydrogenase 1C ADH1C 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
3830 Calreticulin CALR 0.0008
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0008
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0008
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0008
2091 Endoplasmin HSP90B1 0.0008
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0008
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0008
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
5818 Folate receptor alpha FOLR1 0.0007
6034 Hydroxyindole O-methyltransferase ASMT 0.0007
6035 Nuclear receptor ROR-beta RORB 0.0007
6036 Eosinophil peroxidase EPX 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
125 DNA polymerase beta POLB 0.0007
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0007
131 Synaptic vesicular amine transporter SLC18A2 0.0007
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0007
144 Hemoglobin subunit alpha HBA1 0.0006
293 Gamma-glutamyl hydrolase GGH 0.0006
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
765 Indoleamine 2,3-dioxygenase IDO1 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
4920 Peroxidase/catalase katG 0.0006
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
2119 Cytochrome b5 CYB5A 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
4990 PpcA ppcA 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
1650 Heme carrier protein 1 SLC46A1 0.0006
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0006
2230 Catalase CAT 0.0006
3249 Catalase katA 0.0006
3625 Catalase katA 0.0006
4539 Catalase katA 0.0006
4941 Catalase katB 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
6753 Apolipoprotein M APOM 0.0005
2528 Fatty acid metabolism regulator protein fadR 0.0005
6740 Fatty acid metabolism regulator protein fadR 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
6749 Polyprotein Not Available 0.0005
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
2617 Nitric oxide synthase oxygenase nos 0.0005
2701 Nitric oxide synthase oxygenase nos 0.0005
3102 Flavohemoprotein hmp 0.0005
4969 Flavohemoprotein hmp 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
5961 Insulin INS 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
6755 Poliovirus receptor PVR 0.0005
2972 6-deoxyerythronolide B hydroxylase eryF 0.0005
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0004
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
76 Nitric-oxide synthase, brain NOS1 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0004
6524 Protein tonB tonB 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
358 Cystathionine beta-synthase CBS 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2616 Ganglioside GM2 activator GM2A 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
693 Hemoglobin subunit beta HBB 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
6268 Hydroxyacid oxidase 1 HAO1 0.0004
2297 Genome polyprotein Not Available 0.0004
2322 Genome polyprotein Not Available 0.0004
2694 Genome polyprotein Not Available 0.0004
2719 Genome polyprotein Not Available 0.0004
2860 Genome polyprotein Not Available 0.0004
2928 Genome polyprotein Not Available 0.0004
3160 Genome polyprotein Not Available 0.0004
3260 Genome polyprotein Not Available 0.0004
4783 Genome polyprotein Not Available 0.0004
5726 Genome polyprotein Not Available 0.0004
5779 Genome polyprotein Not Available 0.0004
5867 Genome polyprotein Not Available 0.0004
6253 Genome polyprotein Not Available 0.0004
6301 Genome polyprotein Not Available 0.0004
6380 Genome polyprotein Not Available 0.0004
6381 Genome polyprotein Not Available 0.0004
6437 Genome polyprotein Not Available 0.0004
6520 Genome polyprotein Not Available 0.0004
6521 Genome polyprotein Not Available 0.0004
6652 Genome polyprotein Not Available 0.0004
6734 Genome polyprotein Not Available 0.0004
6735 Genome polyprotein Not Available 0.0004
6736 Genome polyprotein Not Available 0.0004
6737 Genome polyprotein Not Available 0.0004
6738 Genome polyprotein Not Available 0.0004
6739 Genome polyprotein Not Available 0.0004
6744 Genome polyprotein Not Available 0.0004
6748 Genome polyprotein Not Available 0.0004
6894 Genome polyprotein Not Available 0.0004
6898 Genome polyprotein Not Available 0.0004
810 Heme oxygenase 1 HMOX1 0.0004
3391 Heme oxygenase 1 pbsA1 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
6228 Nuclear receptor coactivator 1 NCOA1 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0002
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0002
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0002
6168 Solute carrier family 22 member 16 SLC22A16 0.0002
6135 Sodium channel subunit beta-4 SCN4B 0.0002
6134 Sodium channel subunit beta-3 SCN3B 0.0002
6132 Sodium channel subunit beta-1 SCN1B 0.0002
6127 Carbonic anhydrase-related protein CA8 0.0002
6128 Carbonic anhydrase-related protein 10 CA10 0.0002
6133 Sodium channel subunit beta-2 SCN2B 0.0002
6129 Carbonic anhydrase-related protein 11 CA11 0.0002
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0002
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0002
6130 Carbonic anhydrase 13 CA13 0.0002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0002
3007 Carbonic anhydrase 12 CA12 0.0002
4205 Carbonic anhydrase 9 CA9 0.0002
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