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Dihydroneopterin aldolase


Partner ID 2360
Name Dihydroneopterin aldolase
Synonyms 4185
Gene name folB
General function Coenzyme transport and metabolism
Specific function Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Gene sequence + ...

Not Available
Protein sequence + ...

MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
GO Classification
function
aldehyde-lyase activity
dihydroneopterin aldolase activity
catalytic activity
lyase activity
carbon-carbon lyase activity
process
physiological process
metabolism
cellular metabolism
aromatic compound metabolism
folic acid and derivative metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01778 8-Amino-1,3-Dimethyl-3,7-Dihydropurine-2,6-Dione
DB01906 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-Benzoic Acid
DB02119 6-Hydroxymethyl-7,8-Dihydropterin
DB02489 9-Methylguanine
DB03231 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-N-[2-(2-(Hydroxymethyl-Phenylsulfanyl)-Benzyl]-Benzamide
DB03571 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-N-(3,5-Dichlorobenzyl)-Benzamide
DB04168 2-Amino-5-Bromo-6-Phenylpyrimidin-4-Ol
DB04400 7,8-Dihydrobiopterin
DB04425 7,8-Dihydroneopterin
DB06906 2-AMINO-4-HYDROXYPYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

Associated as Prediction

Id Name
DB00120 L-Phenylalanine
DB00125 L-Arginine
DB00135 L-Tyrosine
DB00155 L-Citrulline
DB00360 Tetrahydrobiopterin
DB00368 Norepinephrine
DB00668 Epinephrine
DB00765 Metyrosine
DB00997 Doxorubicin
DB01110 Miconazole
DB01234 Dexamethasone
DB01686 N,N-dimethylarginine
DB01778 8-Amino-1,3-Dimethyl-3,7-Dihydropurine-2,6-Dione
DB01835 4r-Fluoro-N6-Ethanimidoyl-L-Lysine
DB01906 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-Benzoic Acid
DB01997 3-Bromo-7-Nitroindazole
DB02044 N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02119 6-Hydroxymethyl-7,8-Dihydropterin
DB02207 7-Nitroindazole
DB02234 Ethylisothiourea
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02462 Thiocoumarin
DB02489 9-Methylguanine
DB02532 2,4,6-Triaminoquinazoline
DB02533 Aminoguanidine
DB02539 S-Ethylisothiourea
DB02562 Quinonoid 7,8-Tetrahydrobiopterin
DB02596 Alpha,Beta-Methyleneadenosine-5'-Triphosphate
DB02644 N-Omega-Propyl-L-Arginine
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB03014 Heme
DB03100 6-Nitroindazole
DB03144 N-Omega-Hydroxy-L-Arginine
DB03197 6-Hydroxymethylpterin
DB03231 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-N-[2-(2-(Hydroxymethyl-Phenylsulfanyl)-Benzyl]-Benzamide
DB03271 7,8-Dihydro-L-Biopterin
DB03431 Adenosine-5'-Diphosphate
DB03449 N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03552 Meta-Tyrosine
DB03571 3-(5-Amino-7-Hydroxy-[1,2,3]Triazolo[4,5-D]Pyrimidin-2-Yl)-N-(3,5-Dichlorobenzyl)-Benzamide
DB03673 Beta(2-Thienyl)Alanine
DB03953 L-Thiocitrulline
DB04047 [Pterin-6-Yl Methanyl]-Phosphonophosphate
DB04158 6-(Adenosine Tetraphosphate-Methyl)-7,8-Dihydropterin
DB04168 2-Amino-5-Bromo-6-Phenylpyrimidin-4-Ol
DB04400 7,8-Dihydrobiopterin
DB04419 Norleucine
DB04425 7,8-Dihydroneopterin
DB04534 5-Nitroindazole
DB04610 7,8-dihydro-6-hydroxymethyl-7-methyl-7-[2-phenylethyl]-pterin
DB06262 Droxidopa
DB06879 5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE
DB06906 2-AMINO-4-HYDROXYPYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
DB06916 N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE
DB07002 4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile
DB07003 (2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine
DB07007 (3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine
DB07008 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE
DB07011 (3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE
DB07029 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE
DB07306 ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
DB07318 N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE
DB07388 ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
DB07389 N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE
DB07405 1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE
DB08214 4-(1H-IMIDAZOL-1-YL)PHENOL
DB08750 1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE
DB08814 Triflusal
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