DT-Web

DB07348 - 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE


Identification
Name 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE
Accession Number DB07348
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 280.3594
Groups experimental
Monoisotopic Weight 280.167459256
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cytohesin-2
Name Cytohesin-2
Gene Name CYTH2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6222
ADP-ribosylation factor 1
Name ADP-ribosylation factor 1
Gene Name ARF1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7771

Predictions


Id Partner name Gene Name Score
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.229
2281 Haloalkane dehalogenase linB 0.1186
2379 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide DAPP1 0.0673
2348 Pleckstrin homology domain-containing family A member 4 PLEKHA4 0.0671
2355 Tyrosine-protein kinase BTK BTK 0.0671
476 RAC-alpha serine/threonine-protein kinase AKT1 0.041
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0389
5694 Transcription antiterminator licT licT 0.0313
5691 DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC rmlC 0.0313
3361 Serpin B5 SERPINB5 0.0313
3335 Probable GTP-binding protein engB engB 0.0304
3354 Ras-related protein Rap-2a RAP2A 0.0303
1758 GTPase HRas HRAS 0.0253
1673 GTP cyclohydrolase I GCH1 0.024
3302 GTP cyclohydrolase I folE 0.024
3209 Ornithine decarboxylase, inducible odcI 0.0239
2286 Isocitrate dehydrogenase [NADP] icd 0.0237
2302 Isocitrate dehydrogenase [NADP] icd 0.0237
2771 Isocitrate dehydrogenase [NADP] icd 0.0237
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0223
3668 Maltose-binding periplasmic protein precursor malE 0.0219
3311 mRNA-capping enzyme A103R 0.0209
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0209
2647 RNA-directed RNA polymerase P2 0.0208
2592 Beta-galactosidase lacZ 0.0194
315 Arginase-1 ARG1 0.0185
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0184
3261 Signal recognition particle protein ffh 0.0178
1750 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 0.0174
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0167
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0165
6750 ADP-ribosylation factor 6 ARF6 0.0158
3116 Bacterioferritin bfr 0.0156
4906 Bacterioferritin bfr 0.0156
4965 Bacterioferritin bfr 0.0156
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0156
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0156
3173 Enolase eno 0.0156
3709 Glycerol uptake facilitator protein glpF 0.0156
3238 Multidrug resistance protein mexA mexA 0.0156
3393 TGF-beta receptor type-2 TGFBR2 0.0156
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0137
2852 DNA mismatch repair protein mutL mutL 0.0136
24 Thymidylate synthase TMP1 0.0135
359 Thymidylate synthase TYMS 0.0135
2626 Thymidylate synthase thyA 0.0135
2729 Thymidylate synthase thyA 0.0135
5352 Thymidylate synthase THYA 0.0135
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.013
6459 Glycodelin PAEP 0.0126
2297 Genome polyprotein Not Available 0.0125
2322 Genome polyprotein Not Available 0.0125
2694 Genome polyprotein Not Available 0.0125
2719 Genome polyprotein Not Available 0.0125
2860 Genome polyprotein Not Available 0.0125
2928 Genome polyprotein Not Available 0.0125
3160 Genome polyprotein Not Available 0.0125
3260 Genome polyprotein Not Available 0.0125
4783 Genome polyprotein Not Available 0.0125
5726 Genome polyprotein Not Available 0.0125
5779 Genome polyprotein Not Available 0.0125
5867 Genome polyprotein Not Available 0.0125
6253 Genome polyprotein Not Available 0.0125
6301 Genome polyprotein Not Available 0.0125
6380 Genome polyprotein Not Available 0.0125
6381 Genome polyprotein Not Available 0.0125
6437 Genome polyprotein Not Available 0.0125
6520 Genome polyprotein Not Available 0.0125
6521 Genome polyprotein Not Available 0.0125
6652 Genome polyprotein Not Available 0.0125
6734 Genome polyprotein Not Available 0.0125
6735 Genome polyprotein Not Available 0.0125
6736 Genome polyprotein Not Available 0.0125
6737 Genome polyprotein Not Available 0.0125
6738 Genome polyprotein Not Available 0.0125
6739 Genome polyprotein Not Available 0.0125
6744 Genome polyprotein Not Available 0.0125
6748 Genome polyprotein Not Available 0.0125
6894 Genome polyprotein Not Available 0.0125
6898 Genome polyprotein Not Available 0.0125
5618 ADP-ribosylation factor 4 ARF4 0.012
3221 Cytochrome c4 cc4 0.0118
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0118
3191 Histidinol dehydrogenase hisD 0.0118
5630 ADP-ribosylation factor-like protein 5A ARL5A 0.011
2802 Endoglucanase G celCCG 0.0109
4692 A/G-specific adenine glycosylase mutY 0.0109
3197 GDP-mannose mannosyl hydrolase nudD 0.0109
5628 Probable GTPase engC rsgA 0.0109
5627 GDP-mannose 4,6-dehydratase gca 0.0109
1882 Ras-related C3 botulinum toxin substrate 1 RAC1 0.0109
2170 Transforming protein RhoA RHOA 0.0109
5624 GTPase rab6 0.0109
3366 GTP-binding protein engA der 0.0109
4311 tRNA TRDMT1 0.0109
4325 tRNA trmD 0.0109
4328 tRNA trmD 0.0109
740 Argininosuccinate synthase ASS1 0.0108
865 Argininosuccinate synthase ASS1 0.0108
2680 Argininosuccinate synthase argG 0.0108
3194 Argininosuccinate synthase argG 0.0108
4037 Hypothetical protein GPX1 0.0096
4297 Hypothetical protein SP_1951 0.0096
4521 Hypothetical protein BC_2969 0.0096
4540 Hypothetical protein TM_1070 0.0096
4555 Hypothetical protein MT1739 0.0096
4569 Hypothetical protein mshD 0.0096
4578 Hypothetical protein PA3270 0.0096
4747 Hypothetical protein PA3967 0.0096
5177 Hypothetical protein TM_0096 0.0096
5194 Hypothetical protein PA1204 0.0096
5240 Hypothetical protein Rv2991 0.0096
5370 Hypothetical protein TM_1158 0.0096
5710 Hypothetical protein Tb927.5.1360 0.0096
4106 Guanylate kinase GUK1 0.0096
4516 Guanylate kinase gmk 0.0096
4547 Iron binding protein FbpA fbpA 0.0096
4527 Putative hydrolase ycdX ycdX 0.0096
4538 Hypothetical protein VC1899 VC_1899 0.0096
4536 Transcriptional regulator, IclR family TM_0065 0.0096
2501 Protein ygbM ygbM 0.0096
4545 Molybdopterin-converting factor subunit 2 moaE 0.0096
4514 Citrate lyase beta subunit-like protein citE 0.0096
4781 Citrate lyase beta subunit-like protein DR_1240 0.0096
4546 Aminotransferase, putative TM_1131 0.0096
4529 Oxalate decarboxylase oxdC oxdC 0.0096
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0096
4524 Mannose-6-phosphate isomerase yvyI 0.0096
658 Para-aminobenzoate synthase component 1 pabB 0.0096
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0096
4522 Arginine N-succinyltransferase subunit alpha astA 0.0096
4548 Gyrase B gyrB 0.0096
4515 Peripheral plasma membrane protein CASK CASK 0.0096
3115 Ras-related protein Rab-9 RAB9A 0.0095
5619 GDP-mannose 4,6 dehydratase GMDS 0.0095
3396 Elongation factor Tu tufA 0.0095
5621 Elongation factor Tu tuf 0.0095
3170 Elongation factor Tu-B tufB 0.0095
3270 Elongation factor G fusA 0.0095
3107 Putative GTP pyrophosphokinase relA 0.0095
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0093
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.009
444 Alcohol dehydrogenase 1B ADH1B 0.0088
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0087
2521 Cell division protein ftsZ ftsZ 0.0087
3301 Cell division protein ftsZ ftsZ 0.0087
6556 Elongation factor Tu GTP-binding domain-containing protein 1 EFTUD1 0.0087
3759 Glutathione S-transferase gst 0.0084
4541 Glutathione S-transferase GST 0.0084
2929 (S)-2-haloacid dehalogenase dhlB 0.0084
2995 (S)-2-haloacid dehalogenase Not Available 0.0084
4533 Glyoxalase family protein BC_1747 0.0084
3237 Beta-lactamase OXA-2 bla 0.0084
4542 Glutaminase 1 glsA1 0.0084
4544 Glutaminase 1 glsA1 0.0084
4528 Phenazine biosynthesis protein PhzD phzD1 0.0083
4517 Probable butyrate kinase 2 buk2 0.0083
4496 C-terminal-binding protein 1 CTBP1 0.0083
56 Delta-aminolevulinic acid dehydratase ALAD 0.0083
2356 Delta-aminolevulinic acid dehydratase hemB 0.0083
3613 Delta-aminolevulinic acid dehydratase hemB 0.0083
3674 Delta-aminolevulinic acid dehydratase hemB 0.0083
4532 Gephyrin GPHN 0.0083
6790 Elongation factor 2 EEF2 0.0082
6742 Recoverin RCVRN 0.0078
2528 Fatty acid metabolism regulator protein fadR 0.0078
6740 Fatty acid metabolism regulator protein fadR 0.0078
394 Calcineurin subunit B isoform 1 PPP3R1 0.0078
6753 Apolipoprotein M APOM 0.0078
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0078
6747 Chalcone/stilbene synthase family protein MT1417 0.0078
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0078
6743 Non-fluorescent flavoprotein luxF 0.0078
6751 Gag polyprotein gag 0.0078
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0078
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0078
6749 Polyprotein Not Available 0.0078
3583 6-phosphogluconolactonase pgl 0.0077
4531 Putative ketoacyl reductase actIII 0.0077
3467 Methylglyoxal synthase mgsA 0.0077
2775 Dihydroorotate dehydrogenase pyrD 0.0077
2230 Catalase CAT 0.0077
3249 Catalase katA 0.0077
3625 Catalase katA 0.0077
4539 Catalase katA 0.0077
4941 Catalase katB 0.0077
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0077
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0073
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0073
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0073
904 Glutathione S-transferase P GSTP1 0.0071
2688 Peptide deformylase def 0.007
2708 Peptide deformylase def 0.007
3004 Peptide deformylase def 0.007
4337 Peptide deformylase def 0.007
4338 Peptide deformylase def 0.007
5368 Peptide deformylase def 0.007
5371 Peptide deformylase def 0.007
6375 Peptide deformylase def 0.007
6378 Peptide deformylase def 0.007
6379 Peptide deformylase def 0.007
6776 Peptide deformylase def 0.007
6900 Peptide deformylase def 0.007
2632 Adenylosuccinate synthetase purA 0.0069
3323 Adenylosuccinate synthetase purA 0.0069
3975 Adenylosuccinate synthetase ADSS 0.0069
4598 Adenylosuccinate synthetase Adss 0.0069
6817 Adenylosuccinate synthetase purA 0.0069
5961 Insulin INS 0.0068
6527 Lymphocyte antigen 96 LY96 0.0068
6755 Poliovirus receptor PVR 0.0068
2548 Subtilisin Carlsberg apr 0.0067
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0067
6524 Protein tonB tonB 0.0063
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0063
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0063
5626 Nucleoside diphosphate kinase B NME2 0.0061
2616 Ganglioside GM2 activator GM2A 0.0059
5294 Nucleoside diphosphate kinase A NME1 0.0058
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0057
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0057
760 Fibroblast growth factor 1 FGF1 0.0056
3027 Streptavidin Not Available 0.0056
810 Heme oxygenase 1 HMOX1 0.0056
3391 Heme oxygenase 1 pbsA1 0.0056
4210 Toll-like receptor 4 TLR4 0.0054
500 Monocarboxylate transporter 4 SLC16A3 0.0053
864 Gag-Pol polyprotein gag-pol 0.005
2237 Gag-Pol polyprotein gag-pol 0.005
2326 Gag-Pol polyprotein gag-pol 0.005
2451 Gag-Pol polyprotein gag-pol 0.005
2901 Gag-Pol polyprotein gag-pol 0.005
3165 Gag-Pol polyprotein gag-pol 0.005
3722 Gag-Pol polyprotein gag-pol 0.005
6306 Gag-Pol polyprotein gag-pol 0.005
6624 Gag-Pol polyprotein gag-pol 0.005
76 Nitric-oxide synthase, brain NOS1 0.0048
5682 Ribonuclease pancreatic RNASE1 0.0048
6085 Fatty acid-binding protein, intestinal FABP2 0.0044
2427 Ferrichrome-iron receptor fhuA 0.0044
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0043
768 FK506-binding protein 1A FKBP1A 0.0042
6228 Nuclear receptor coactivator 1 NCOA1 0.0042
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.004
6013 Cytochrome P450 2E1 CYP2E1 0.0039
357 Carbonic anhydrase 2 CA2 0.0035
1588 Multidrug resistance protein 1 ABCB1 0.0034
465 Calmodulin CALM1 0.0031
587 Serum albumin ALB 0.0021
↑