DT-Web

DB04714 - ISOPENTENYL PYROPHOSPHATE


Identification
Name ISOPENTENYL PYROPHOSPHATE
Accession Number DB04714
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 246.0921
Groups experimental
Monoisotopic Weight 246.005825762
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Undecaprenyl pyrophosphate synthetase
Name Undecaprenyl pyrophosphate synthetase
Gene Name uppS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7202
Farnesyl pyrophosphate synthetase
Name Farnesyl pyrophosphate synthetase
Gene Name FDPS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2357
Geranylgeranyl pyrophosphate synthetase
Name Geranylgeranyl pyrophosphate synthetase
Gene Name GGPS1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7199
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Name 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gene Name ispF
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.0434
Undecaprenyl pyrophosphate synthase
Name Undecaprenyl pyrophosphate synthase
Gene Name uppS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Name 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Gene Name ispH
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0292

Predictions


Id Partner name Gene Name Score
6547 Isopentenyl-diphosphate Delta-isomerase 1 IDI1 0.3959
6597 Mevalonate kinase MVK 0.1463
6368 Dehydrosqualene synthase crtM 0.1174
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.1168
6576 Geranylgeranyl transferase type-2 subunit beta RABGGTB 0.1013
6575 Geranylgeranyl transferase type-2 subunit alpha RABGGTA 0.1012
4128 Protein farnesyltransferase subunit beta FNTB 0.0844
4129 Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit FNTA 0.0828
6595 Lantibiotic nisin-Z nisZ 0.0722
6574 GTPase KRas KRAS 0.0578
3188 IspD/ispF bifunctional enzyme [Includes: 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase ispDF 0.0541
6647 Geranyltranstransferase (Farnesyldiphosphate synthase) ispA 0.0522
1994 Geranylgeranyl transferase type-1 subunit beta PGGT1B 0.0496
862 Multidrug resistance-associated protein 1 ABCC1 0.0474
6540 Prenyltransferase Not Available 0.0468
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0434
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0434
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0434
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0434
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0434
2756 Geranyltranstransferase ispA 0.042
6056 Receptor-type tyrosine-protein phosphatase epsilon PTPRE 0.0369
1376 Tyrosine-protein phosphatase non-receptor type 4 PTPN4 0.0369
290 Prostaglandin G/H synthase 2 PTGS2 0.0349
4284 Pentaerythritol tetranitrate reductase onr 0.0348
6055 Receptor-type tyrosine-protein phosphatase S PTPRS 0.0322
6057 V-type proton ATPase catalytic subunit A ATP6V1A 0.0301
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