DT-Web

Dehydrosqualene synthase


Partner ID 6368
Name Dehydrosqualene synthase
Synonyms 8504
Gene name crtM
General function Lipid transport and metabolism
Specific function Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid dehydrosqualene (4,4'-diapophytoene). This is the initial step in the biosynthesis of staphyloxanthin, an orange carotenoid present in most staphylococci strains
Gene sequence + ...

Not Available
Protein sequence + ...

MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
GO Classification
function
catalytic activity
transferase activity
process
physiological process
metabolism
biosynthesis
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Drugs


Associated as Target

Id Name
DB04695 FARNESYL THIOPYROPHOSPHATE
DB07420 (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid
DB07424 tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate

Associated as Prediction

Id Name
DB00399 Zoledronate
DB02552 Geranyl Diphosphate
DB04695 FARNESYL THIOPYROPHOSPHATE
DB04714 ISOPENTENYL PYROPHOSPHATE
DB06830 (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
DB06931 (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
DB07221 (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM
DB07404 (1-HYDROXY-1-PHOSPHONO-2-[1,1';3',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID
DB07409 (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID
DB07410 [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
DB07420 (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid
DB07424 tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate
DB07426 [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
DB07780 FARNESYL DIPHOSPHATE
DB07841 GERANYLGERANYL DIPHOSPHATE
DB07873 (1-HYDROXYDODECANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
DB08529 (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)
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