DT-Web

DB03963 - S-(Dimethylarsenic)Cysteine


Identification
Name S-(Dimethylarsenic)Cysteine
Accession Number DB03963 (EXPT00832)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 225.141
Groups experimental
Monoisotopic Weight 224.98047074
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Toll-like receptor 2
Name Toll-like receptor 2
Gene Name TLR2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8377
Capsid protein P40
Name Capsid protein P40
Gene Name UL80
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.6008
Gag-Pol polyprotein
Name Gag-Pol polyprotein
Gene Name gag-pol
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.9109
Nitric-oxide synthase, endothelial
Name Nitric-oxide synthase, endothelial
Gene Name NOS3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5563
Coatomer subunit gamma
Name Coatomer subunit gamma
Gene Name COPG
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9778
Genome polyprotein
Name Genome polyprotein
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0125
DNA-repair protein XRCC4
Name DNA-repair protein XRCC4
Gene Name XRCC4
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9782
Peptide methionine sulfoxide reductase msrA
Name Peptide methionine sulfoxide reductase msrA
Gene Name msrA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9783

Predictions


Id Partner name Gene Name Score
864 Gag-Pol polyprotein gag-pol 1.9109
2326 Gag-Pol polyprotein gag-pol 1.9109
2451 Gag-Pol polyprotein gag-pol 1.9109
2901 Gag-Pol polyprotein gag-pol 1.9109
3165 Gag-Pol polyprotein gag-pol 1.9109
3722 Gag-Pol polyprotein gag-pol 1.9109
6306 Gag-Pol polyprotein gag-pol 1.9109
6624 Gag-Pol polyprotein gag-pol 1.9109
3569 Capsid protein P40 BVRF2 1.6008
76 Nitric-oxide synthase, brain NOS1 0.2014
2349 Subtilisin Savinase Not Available 0.1768
2589 Alkaline protease Not Available 0.1767
7 Nitric oxide synthase, inducible NOS2 0.1592
2378 Carboxymethylenebutenolidase clcD 0.1539
5372 Proteinase inhibitor I4, serpin Tfu_1933 0.1467
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0753
6755 Poliovirus receptor PVR 0.0569
822 Aldose reductase AKR1B1 0.0466
3382 Glycolipid transfer protein GLTP 0.0358
6316 ADP-ribosylation factor 1 ARF1 0.0258
1673 GTP cyclohydrolase I GCH1 0.0239
3302 GTP cyclohydrolase I folE 0.0239
3209 Ornithine decarboxylase, inducible odcI 0.0239
298 Renin REN 0.0221
3354 Ras-related protein Rap-2a RAP2A 0.0208
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0208
3335 Probable GTP-binding protein engB engB 0.0208
3311 mRNA-capping enzyme A103R 0.0208
2647 RNA-directed RNA polymerase P2 0.0208
828 Phenylalanine-4-hydroxylase PAH 0.0204
3109 Phenylalanine-4-hydroxylase phhA 0.0204
1758 GTPase HRas HRAS 0.0173
1750 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 0.0173
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0153
6749 Polyprotein Not Available 0.0149
6751 Gag polyprotein gag 0.0147
6753 Apolipoprotein M APOM 0.0142
2528 Fatty acid metabolism regulator protein fadR 0.0142
6740 Fatty acid metabolism regulator protein fadR 0.0142
6742 Recoverin RCVRN 0.0142
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0142
394 Calcineurin subunit B isoform 1 PPP3R1 0.0142
6743 Non-fluorescent flavoprotein luxF 0.0142
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0142
6747 Chalcone/stilbene synthase family protein MT1417 0.0142
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0142
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0142
2617 Nitric oxide synthase oxygenase nos 0.014
2701 Nitric oxide synthase oxygenase nos 0.014
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0136
1588 Multidrug resistance protein 1 ABCB1 0.0128
2297 Genome polyprotein Not Available 0.0125
2322 Genome polyprotein Not Available 0.0125
2694 Genome polyprotein Not Available 0.0125
2719 Genome polyprotein Not Available 0.0125
2860 Genome polyprotein Not Available 0.0125
3160 Genome polyprotein Not Available 0.0125
3260 Genome polyprotein Not Available 0.0125
4783 Genome polyprotein Not Available 0.0125
5726 Genome polyprotein Not Available 0.0125
5779 Genome polyprotein Not Available 0.0125
5867 Genome polyprotein Not Available 0.0125
6253 Genome polyprotein Not Available 0.0125
6301 Genome polyprotein Not Available 0.0125
6380 Genome polyprotein Not Available 0.0125
6381 Genome polyprotein Not Available 0.0125
6437 Genome polyprotein Not Available 0.0125
6520 Genome polyprotein Not Available 0.0125
6521 Genome polyprotein Not Available 0.0125
6652 Genome polyprotein Not Available 0.0125
6734 Genome polyprotein Not Available 0.0125
6735 Genome polyprotein Not Available 0.0125
6736 Genome polyprotein Not Available 0.0125
6737 Genome polyprotein Not Available 0.0125
6738 Genome polyprotein Not Available 0.0125
6739 Genome polyprotein Not Available 0.0125
6744 Genome polyprotein Not Available 0.0125
6748 Genome polyprotein Not Available 0.0125
6894 Genome polyprotein Not Available 0.0125
6898 Genome polyprotein Not Available 0.0125
5961 Insulin INS 0.0123
6527 Lymphocyte antigen 96 LY96 0.0123
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0114
6750 ADP-ribosylation factor 6 ARF6 0.0114
6524 Protein tonB tonB 0.0114
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0114
2616 Ganglioside GM2 activator GM2A 0.0107
134 Tryptophan 5-hydroxylase 1 TPH1 0.0104
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0103
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0103
4210 Toll-like receptor 4 TLR4 0.0099
315 Arginase-1 ARG1 0.0097
676 Tyrosine 3-monooxygenase TH 0.0091
6085 Fatty acid-binding protein, intestinal FABP2 0.0081
2427 Ferrichrome-iron receptor fhuA 0.008
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0077
768 FK506-binding protein 1A FKBP1A 0.0076
6228 Nuclear receptor coactivator 1 NCOA1 0.0076
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0072
740 Argininosuccinate synthase ASS1 0.0067
865 Argininosuccinate synthase ASS1 0.0067
2680 Argininosuccinate synthase argG 0.0067
3194 Argininosuccinate synthase argG 0.0067
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0067
465 Calmodulin CALM1 0.0057
290 Prostaglandin G/H synthase 2 PTGS2 0.0054
577 Argininosuccinate lyase ASL 0.0049
1814 Protein-arginine deiminase type-4 PADI4 0.0046
834 Arginase-2, mitochondrial ARG2 0.0044
843 NG,NG-dimethylarginine dimethylaminohydrolase 1 DDAH1 0.0043
670 NG,NG-dimethylarginine dimethylaminohydrolase 2 DDAH2 0.0043
4066 Protein-arginine deiminase type-1 PADI1 0.0043
4067 Protein-arginine deiminase type-3 PADI3 0.0043
4065 Protein-arginine deiminase type-6 PADI6 0.0043
4068 Protein-arginine deiminase type-2 PADI2 0.0043
499 Arginine decarboxylase ADC 0.0041
336 Ornithine carbamoyltransferase, mitochondrial OTC 0.004
587 Serum albumin ALB 0.004
58 Cationic amino acid transporter 4 SLC7A4 0.0038
150 Cationic amino acid transporter 3 SLC7A3 0.0038
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.0038
6151 Monocarboxylate transporter 10 SLC16A10 0.0026
833 Organic cation/carnitine transporter 1 SLC22A4 0.0025
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0023
118 Organic cation/carnitine transporter 2 SLC22A5 0.0022
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0021
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0021
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0021
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0021
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0021
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0021
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.002
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0019
6030 Cytochrome P450 2B6 CYP2B6 0.0019
6168 Solute carrier family 22 member 16 SLC22A16 0.0017
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0017
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0017
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0017
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0017
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0016
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0016
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0015
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0015
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0015
4120 NADPH--cytochrome P450 reductase POR 0.0014
4512 Cytochrome P450 3A4 CYP3A4 0.0014
4119 Cytochrome P450 2D6 CYP2D6 0.0014
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0013
260 Cytochrome P450 51 ERG11 0.0013
761 Cytochrome P450 51 ERG11 0.0013
3163 Cytochrome P450 51 cyp51 0.0013
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0013
6137 Multidrug resistance-associated protein 6 ABCC6 0.0012
6148 Multidrug resistance-associated protein 7 ABCC10 0.0012
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0012
3947 Xanthine dehydrogenase/oxidase XDH 0.0012
817 DNA topoisomerase 2-alpha TOP2A 0.0011
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0011
3811 Cytochrome P450 19A1 CYP19A1 0.0011
776 Bile salt export pump ABCB11 0.0011
1898 Cytochrome P450 1B1 CYP1B1 0.001
862 Multidrug resistance-associated protein 1 ABCC1 0.001
5718 Cytochrome P450 2A6 CYP2A6 0.0009
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0009
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0009
4757 Cytochrome P450 2C9 CYP2C9 0.0009
6013 Cytochrome P450 2E1 CYP2E1 0.0008
6016 Cytochrome P450 2C19 CYP2C19 0.0007
4905 Cytochrome c2 Not Available 0.0007
4939 Cytochrome c2 cycA 0.0007
4964 Cytochrome c2 cycA 0.0007
4979 Cytochrome c2 cycA 0.0007
6673 Cytochrome c2 cycA 0.0007
4916 Cyanoglobin glbN 0.0007
4943 Cytochrome c6 petJ 0.0007
4954 Soluble cytochrome b558 Not Available 0.0007
4934 Cytochrome c-551 nirM 0.0007
5218 Cytochrome c-551 nirM 0.0007
4936 Cytochrome c2 iso-2 Not Available 0.0007
4994 Hemoglobin-like protein HbO glbO 0.0007
4915 Cytochrome c-550 psbV 0.0007
4959 Cytochrome c-550 psbV 0.0007
5216 Cytochrome c-550 psbV 0.0007
4925 Cytochrome c-type protein SHP shp 0.0007
4998 Hemoglobin-like protein yjbI yjbI 0.0007
4947 Bacterial hemoglobin vhb 0.0007
5000 HemO hemO 0.0007
4975 Cytochrome c-556 RPA3973 0.0007
4942 Diheme cytochrome c napB napB 0.0007
4984 Neuroglobin NGB 0.0007
3116 Bacterioferritin bfr 0.0007
4906 Bacterioferritin bfr 0.0007
4965 Bacterioferritin bfr 0.0007
4961 Hemophore HasA hasA 0.0007
4910 Cytoglobin CYGB 0.0007
4907 Cytochrome c-L moxG 0.0007
6865 Cytochrome c-L moxG 0.0007
4981 Iron-starvation protein PigA pigA 0.0007
4909 CooA protein cooA 0.0007
4935 Cytochrome c-554 cycA1 0.0007
644 Heme oxygenase 2 HMOX2 0.0007
4982 Heme oxygenase 2 pbsA2 0.0007
4972 P450cin cinA 0.0007
4960 Putative cytochrome P450-family protein SCO7417 0.0007
4764 Cytochrome P450 165C4 CYP165C4 0.0007
4937 Cytochrome oxidase subunit II rcoxA 0.0007
4971 Nonaheme cytochrome c hmcA 0.0007
4931 Cytochrome P450 167A1 CYP167A1 0.0007
4989 Cytochrome c551 peroxidase ccp 0.0007
5222 Cytochrome c551 peroxidase ccpA 0.0007
4976 Apocytochrome f petA 0.0007
6407 Apocytochrome f petA 0.0007
4904 Cytochrome c family protein GSU1996 0.0007
4999 Cytochrome P450 165B3 CYP165B3 0.0007
4926 Heme-based aerotactic transducer hemAT hemAT 0.0007
4922 Cytochrome c, putative SO_4144 0.0007
4952 Catalase/peroxidase katA 0.0007
3093 Catalase HPII katE 0.0007
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0007
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0007
4993 Hydroxylamine oxidoreductase hao1 0.0007
4903 Methyl-accepting chemotaxis protein Tar4 0.0007
4200 Cytochrome P450 1A2 CYP1A2 0.0007
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4990 PpcA ppcA 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
4920 Peroxidase/catalase katG 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
4948 Cytochrome c-553 Not Available 0.0006
4902 Nine-heme cytochrome c Ddes_2038 0.0006
4923 Cytochrome c3 DvMF_2499 0.0006
4945 Cytochrome c3 Not Available 0.0006
4949 Cytochrome c3 DVU_3171 0.0006
4968 Cytochrome c3 cytc3 0.0006
4997 Cytochrome c3 SO_2727 0.0006
5219 Cytochrome c3 cyd 0.0006
2119 Cytochrome b5 CYB5A 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
3189 High-molecular-weight cytochrome c hmcA 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
4386 Hemoglobin-like protein HbN glbN 0.0006
3670 Soluble cytochrome b562 precursor cybC 0.0006
3291 Cytochrome c-552 cycA 0.0006
4927 Cytochrome c-552 nrfA 0.0006
4938 Cytochrome c-552 cycA 0.0006
4953 Cytochrome c-552 nrfA 0.0006
5217 Cytochrome c-552 cycM 0.0006
3102 Flavohemoprotein hmp 0.0006
4969 Flavohemoprotein hmp 0.0006
3411 Cytochrome P450 121 cyp121 0.0006
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
3221 Cytochrome c4 cc4 0.0005
2230 Catalase CAT 0.0005
3249 Catalase katA 0.0005
3625 Catalase katA 0.0005
4539 Catalase katA 0.0005
4941 Catalase katB 0.0005
4608 Putative cytochrome P450 SCO1207 0.0005
4963 Putative cytochrome P450 SCO2884 0.0005
6254 Putative cytochrome P450 SCO6998 0.0005
605 Fumarate reductase flavoprotein subunit frdA 0.0005
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0005
3673 Fumarate reductase flavoprotein subunit fccA 0.0005
4912 Fumarate reductase flavoprotein subunit ifcA 0.0005
6549 Fumarate reductase flavoprotein subunit frdA 0.0005
2972 6-deoxyerythronolide B hydroxylase eryF 0.0005
1507 Cytochrome c CYCS 0.0005
693 Hemoglobin subunit beta HBB 0.0005
518 Peroxidase/catalase T katG 0.0005
6268 Hydroxyacid oxidase 1 HAO1 0.0005
810 Heme oxygenase 1 HMOX1 0.0004
3391 Heme oxygenase 1 pbsA1 0.0004
2298 Cytochrome P450-cam camC 0.0004
358 Cystathionine beta-synthase CBS 0.0004
275 Arachidonate 5-lipoxygenase ALOX5 0.0003
6106 Cytochrome P450 2C18 CYP2C18 0.0003
20 Prostaglandin G/H synthase 1 PTGS1 0.0002
4924 Cytochrome P450 2C8 CYP2C8 0.0002
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