| Name |
Small inducible cytokine A8 |
| Synonyms |
7222 |
| Gene name |
CCL8 |
| General function |
Involved in chemokine activity |
| Specific function |
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8 |
| Gene sequence |
+ ...
ATGAAGGTTTCTGCAGCGCTTCTGTGCCTGCTGCTCATGGCAGCCACTTTCAGCCCTCAGGGACTTGCTCAGCCAGATTCAGTTTCCATTCCAATCACCTGCTGCTTTAACGTGATCAATAGGAAAATTCCTATCCAGAGGCTGGAGAGCTACACAAGAATCACCAACATCCAATGTCCCAAGGAAGCTGTGATCTTCAAGACCCAACGGGGCAAGGAGGTCTGTGCTGACCCCAAGGAGAGATGGGTCAGGGATTCCATGAAGCATCTGGACCAAATATTTCAAAATCTGAAGCCATGA
|
| Protein sequence |
+ ...
MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP
|
| GO Classification |
| component |
| cell |
| membrane |
| extracellular region |
| function |
| chemokine activity |
| signal transducer activity |
| receptor binding |
| cytokine activity |
| process |
| immune response |
| response to stimulus |
| response to biotic stimulus |
| defense response |
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www.drugbank.ca
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