DT-Web

DB03880 - Batimastat


Identification
Name Batimastat
Accession Number DB03880 (EXPT00627)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 477.64
Groups experimental
Monoisotopic Weight 477.175597875
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Neutrophil collagenase
Name Neutrophil collagenase
Gene Name MMP8
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.9004
Macrophage metalloelastase
Name Macrophage metalloelastase
Gene Name MMP12
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6724
Matrix metalloproteinase-16
Name Matrix metalloproteinase-16
Gene Name MMP16
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.4467
Disintegrin and metalloproteinase domain-containing protein 28
Name Disintegrin and metalloproteinase domain-containing protein 28
Gene Name ADAM28
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5762
A disintegrin and metalloproteinase with thrombospondin motifs 5
Name A disintegrin and metalloproteinase with thrombospondin motifs 5
Gene Name ADAMTS5
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7177

Predictions


Id Partner name Gene Name Score
1167 Interstitial collagenase MMP1 0.1647
6607 Aggrecan core protein ACAN 0.1195
2489 Lethal factor lef 0.0867
6703 Lethal factor lef 0.0867
6188 Stromelysin-2 MMP10 0.0782
6195 Matrix metalloproteinase-20 MMP20 0.078
370 Urease alpha subunit ureC 0.0676
1926 Stromelysin-1 MMP3 0.0525
6198 Matrix metalloproteinase-24 MMP24 0.0512
6191 Matrix metalloproteinase-14 MMP14 0.0498
6192 Matrix metalloproteinase-15 MMP15 0.0498
6201 Matrix metalloproteinase-27 MMP27 0.0494
6200 Matrix metalloproteinase-26 MMP26 0.0494
6199 Matrix metalloproteinase-25 MMP25 0.0493
6197 Matrix metalloproteinase-23 MMP23A 0.0493
6194 Matrix metalloproteinase-19 MMP19 0.0493
6193 Matrix metalloproteinase-17 MMP17 0.0493
6196 Matrix metalloproteinase-21 MMP21 0.0493
6202 Matrix metalloproteinase-28 MMP28 0.0493
6190 Stromelysin-3 MMP11 0.044
6189 Matrilysin MMP7 0.0394
707 72 kDa type IV collagenase MMP2 0.034
1330 Collagenase 3 MMP13 0.0299
65 Matrix metalloproteinase-9 Not Available 0.0299
4385 Cytochrome c' Not Available 0.0257
4967 Cytochrome c' cycA 0.0257
5038 Cytochrome c' Not Available 0.0257
5223 Cytochrome c' cycP 0.0257
5036 Small inducible cytokine A8 CCL8 0.0257
5012 Ig lambda chain V-II region MGC Not Available 0.0257
5006 RNASE4 protein RNASE4 0.0223
5023 Glycoside hydrolase Not Available 0.0223
5024 Glycoside hydrolase Not Available 0.0223
4771 Dissimilatory copper-containing nitrite reductase nir 0.0223
2149 Angiogenin ANG 0.0206
4905 Cytochrome c2 Not Available 0.0206
4939 Cytochrome c2 cycA 0.0206
4964 Cytochrome c2 cycA 0.0206
4979 Cytochrome c2 cycA 0.0206
6673 Cytochrome c2 cycA 0.0206
3030 Salivary alpha-amylase AMY1A 0.0186
2430 Chondroitinase B cslB 0.0165
183 Vascular endothelial growth factor A VEGFA 0.0143
4513 Pancreatic alpha-amylase AMY2A 0.0141
↑