Name |
DNA protection during starvation protein |
Synonyms |
6866 |
Gene name |
dps |
General function |
Involved in oxidoreductase activity |
Specific function |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. It efficiently inhibits hydroxyl radical production by the Fenton reaction. Does not bind DNA |
Gene sequence |
+ ...
ATGAAGACGCACAAGACGAAGAACGACCTGCCTTCCAACGCCAAGTCGACCGTGATCGGCATTCTGAACGAATCTCTCGCCTCGGTGATCGATCTCGCGCTTGTCACCAAGCAGGCGCACTGGAACCTGAAAGGCCCGCAATTCATCGCCGTCCACGAACTTCTCGACACCTTCCGCACCCAGCTCGACAATCACGGCGATACGATTGCCGAACGCGTCGTGCAGCTGGGCGGCACCGCACTCGGCAGCCTGCAAGCCGTCTCCTCGACGACGAAGCTCAAGGCCTATCCGACCGATATCTATAAAATCCACGATCATCTCGACGCTCTGATCGAGCGTTATGGCGAAGTCGCCAACATGATCCGCAAGGCGATCGACGATTCCGACGAAGCCGGCGATCCGACGACGGCCGATATCTTCACCGCCGCCTCGCGCGATCTCGACAAGTCACTGTGGTTCCTCGAAGCCCATGTGCAGGAAAAGAGCTGA
|
Protein sequence |
+ ...
MKTHKTKNDLPSNAKSTVIGILNESLASVIDLALVTKQAHWNLKGPQFIAVHELLDTFRTQLDNHGDTIAERVVQLGGTALGSLQAVSSTTKLKAYPTDIYKIHDHLDALIERYGEVANMIRKAIDDSDEAGDPTTADIFTAASRDLDKSLWFLEAHVQEKS
|
GO Classification |
function |
binding |
ion binding |
cation binding |
transition metal ion binding |
iron ion binding |
ferric iron binding |
process |
cell homeostasis |
cell ion homeostasis |
cation homeostasis |
di-, tri-valent inorganic cation homeostasis |
iron ion homeostasis |
response to stimulus |
physiological process |
response to stress |
homeostasis |
|
See more information at →
www.drugbank.ca
|