DT-Web

DB03754 - Tris(Hydroxymethyl)Aminomethane


Identification
Name Tris(Hydroxymethyl)Aminomethane
Accession Number DB03754 (EXPT03072)
Type small molecule
Description An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 122.143
Groups experimental
Monoisotopic Weight 122.081718255
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Autolysin
Name Autolysin
Gene Name lytA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.6111
Cytochrome c4
Name Cytochrome c4
Gene Name cc4
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7852
Soluble calcium-activated nucleotidase 1
Name Soluble calcium-activated nucleotidase 1
Gene Name CANT1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8512
Lipoprotein nlpI precursor
Name Lipoprotein nlpI precursor
Gene Name nlpI
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9873
DNA protection during starvation protein
Name DNA protection during starvation protein
Gene Name dps
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9879
UPF0010 protein HI1317
Name UPF0010 protein HI1317
Gene Name HI_1317
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9876
Endonuclease VIII-like 1
Name Endonuclease VIII-like 1
Gene Name NEIL1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9876
Cholera enterotoxin subunit B
Name Cholera enterotoxin subunit B
Gene Name ctxB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0105
S-adenosylmethionine decarboxylase proenzyme
Name S-adenosylmethionine decarboxylase proenzyme
Gene Name AMD1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2821
Biotin synthase
Name Biotin synthase
Gene Name bioB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1838
Vascular endothelial growth factor A
Name Vascular endothelial growth factor A
Gene Name VEGFA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9637
6-phosphogluconolactonase
Name 6-phosphogluconolactonase
Gene Name pgl
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8056
Decorin
Name Decorin
Gene Name DCN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
4511 Truncated transposase Not Available 0.2809
2334 Dethiobiotin synthetase bioD 0.2282
6555 Dethiobiotin synthetase bioD 0.2282
6530 Pancreatic lipase-related protein 2 PNLIPRP2 0.1405
5377 Placenta growth factor PGF 0.1355
2429 Putrescine-binding periplasmic protein potF 0.1269
6692 Cholera toxin beta subunit ctxB 0.1204
2427 Ferrichrome-iron receptor fhuA 0.0802
449 Ornithine decarboxylase ODC1 0.0775
2693 Heat-labile enterotoxin B chain eltB 0.0761
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0715
330 Spermidine synthase SRM 0.0527
3038 Spermidine synthase speE 0.0527
411 Glycine N-methyltransferase GNMT 0.0504
833 Organic cation/carnitine transporter 1 SLC22A4 0.0478
1334 Tissue factor pathway inhibitor TFPI 0.0471
2058 P-selectin SELP 0.0468
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0429
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0425
1719 Heparanase HPSE 0.0414
358 Cystathionine beta-synthase CBS 0.0394
1507 Cytochrome c CYCS 0.0316
309 Antithrombin-III SERPINC1 0.0304
3810 Catechol O-methyltransferase COMT 0.0293
6013 Cytochrome P450 2E1 CYP2E1 0.0289
587 Serum albumin ALB 0.026
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0257
4948 Cytochrome c-553 Not Available 0.0256
4923 Cytochrome c3 DvMF_2499 0.0256
4945 Cytochrome c3 Not Available 0.0256
4949 Cytochrome c3 DVU_3171 0.0256
4968 Cytochrome c3 cytc3 0.0256
4997 Cytochrome c3 SO_2727 0.0256
5219 Cytochrome c3 cyd 0.0256
4902 Nine-heme cytochrome c Ddes_2038 0.0255
3189 High-molecular-weight cytochrome c hmcA 0.0255
4757 Cytochrome P450 2C9 CYP2C9 0.0248
5221 Cytochrome c3, 13 kDa Not Available 0.0245
3152 Cytochrome c'' cycA 0.0245
3709 Glycerol uptake facilitator protein glpF 0.0245
3116 Bacterioferritin bfr 0.0244
4906 Bacterioferritin bfr 0.0244
4965 Bacterioferritin bfr 0.0244
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0244
5220 Split-Soret cytochrome c Ddes_2150 0.0244
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0244
3700 Cytochrome c-552 precursor nrfA 0.0244
3238 Multidrug resistance protein mexA mexA 0.0244
3173 Enolase eno 0.0244
3393 TGF-beta receptor type-2 TGFBR2 0.0244
5006 RNASE4 protein RNASE4 0.0244
4386 Hemoglobin-like protein HbN glbN 0.0236
2149 Angiogenin ANG 0.0225
4533 Glyoxalase family protein BC_1747 0.0222
3127 Nitrite reductase nirS 0.0213
3284 Nitrite reductase nirS 0.0213
2852 DNA mismatch repair protein mutL mutL 0.0213
6459 Glycodelin PAEP 0.0197
4692 A/G-specific adenine glycosylase mutY 0.0194
2802 Endoglucanase G celCCG 0.0188
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0185
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0185
3191 Histidinol dehydrogenase hisD 0.0185
5787 Angiopoietin-1 receptor TEK 0.0182
740 Argininosuccinate synthase ASS1 0.018
865 Argininosuccinate synthase ASS1 0.018
2680 Argininosuccinate synthase argG 0.018
3194 Argininosuccinate synthase argG 0.018
4311 tRNA TRDMT1 0.0176
4325 tRNA trmD 0.0176
4328 tRNA trmD 0.0176
5036 Small inducible cytokine A8 CCL8 0.017
5012 Ig lambda chain V-II region MGC Not Available 0.017
6316 ADP-ribosylation factor 1 ARF1 0.0166
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0157
5023 Glycoside hydrolase Not Available 0.0148
5024 Glycoside hydrolase Not Available 0.0148
4771 Dissimilatory copper-containing nitrite reductase nir 0.0148
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0147
6016 Cytochrome P450 2C19 CYP2C19 0.0146
1654 Interleukin-1 beta IL1B 0.0145
844 Epidermal growth factor receptor EGFR 0.0145
4545 Molybdopterin-converting factor subunit 2 moaE 0.0145
4527 Putative hydrolase ycdX ycdX 0.0145
4037 Hypothetical protein GPX1 0.0145
4297 Hypothetical protein SP_1951 0.0145
4521 Hypothetical protein BC_2969 0.0145
4540 Hypothetical protein TM_1070 0.0145
4555 Hypothetical protein MT1739 0.0145
4569 Hypothetical protein mshD 0.0145
4578 Hypothetical protein PA3270 0.0145
4747 Hypothetical protein PA3967 0.0145
5177 Hypothetical protein TM_0096 0.0145
5194 Hypothetical protein PA1204 0.0145
5240 Hypothetical protein Rv2991 0.0145
5370 Hypothetical protein TM_1158 0.0145
5710 Hypothetical protein Tb927.5.1360 0.0145
4536 Transcriptional regulator, IclR family TM_0065 0.0145
4514 Citrate lyase beta subunit-like protein citE 0.0144
4781 Citrate lyase beta subunit-like protein DR_1240 0.0144
4524 Mannose-6-phosphate isomerase yvyI 0.0144
4522 Arginine N-succinyltransferase subunit alpha astA 0.0144
4106 Guanylate kinase GUK1 0.0144
4516 Guanylate kinase gmk 0.0144
4538 Hypothetical protein VC1899 VC_1899 0.0144
4529 Oxalate decarboxylase oxdC oxdC 0.0144
4548 Gyrase B gyrB 0.0144
4546 Aminotransferase, putative TM_1131 0.0144
658 Para-aminobenzoate synthase component 1 pabB 0.0144
2501 Protein ygbM ygbM 0.0144
4547 Iron binding protein FbpA fbpA 0.0144
4515 Peripheral plasma membrane protein CASK CASK 0.0144
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0144
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0144
5416 Coat protein VP1 Not Available 0.0142
3030 Salivary alpha-amylase AMY1A 0.0141
444 Alcohol dehydrogenase 1B ADH1B 0.0141
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0141
4992 Cytochrome c peroxidase Not Available 0.0139
3817 Complement C1q subcomponent subunit C C1QC 0.0138
3816 Complement C1q subcomponent subunit B C1QB 0.0138
3815 Complement C1q subcomponent subunit A C1QA 0.0138
5414 Fiber protein L5 0.0138
5418 Fiber protein L5 0.0138
1756 E-selectin SELE 0.0137
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0137
494 Caspase-1 CASP1 0.0136
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.0136
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.0136
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.0136
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.0136
3814 Complement C1r subcomponent C1R 0.0136
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.0135
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.013
3547 Enterotoxin type B entB 0.013
2324 Botulinum neurotoxin type B botB 0.013
5682 Ribonuclease pancreatic RNASE1 0.0128
2430 Chondroitinase B cslB 0.0127
3759 Glutathione S-transferase gst 0.0126
4541 Glutathione S-transferase GST 0.0126
2929 (S)-2-haloacid dehalogenase dhlB 0.0126
2995 (S)-2-haloacid dehalogenase Not Available 0.0126
3261 Signal recognition particle protein ffh 0.0126
4542 Glutaminase 1 glsA1 0.0126
4544 Glutaminase 1 glsA1 0.0126
56 Delta-aminolevulinic acid dehydratase ALAD 0.0126
2356 Delta-aminolevulinic acid dehydratase hemB 0.0126
3613 Delta-aminolevulinic acid dehydratase hemB 0.0126
3674 Delta-aminolevulinic acid dehydratase hemB 0.0126
4528 Phenazine biosynthesis protein PhzD phzD1 0.0126
4496 C-terminal-binding protein 1 CTBP1 0.0126
3237 Beta-lactamase OXA-2 bla 0.0126
4517 Probable butyrate kinase 2 buk2 0.0126
4532 Gephyrin GPHN 0.0126
1374 Natriuretic peptides B NPPB 0.0122
1827 Gap junction alpha-1 protein GJA1 0.0121
1908 Vascular cell adhesion protein 1 VCAM1 0.0121
4857 Zinc-alpha-2-glycoprotein AZGP1 0.012
1130 Lithostathine 1 alpha REG1A 0.012
275 Arachidonate 5-lipoxygenase ALOX5 0.012
3629 Endo-N-acetylneuraminidase Not Available 0.012
22 30S ribosomal protein S4 rpsD 0.0117
6714 30S ribosomal protein S4 rpsD 0.0117
3467 Methylglyoxal synthase mgsA 0.0116
904 Glutathione S-transferase P GSTP1 0.0116
2775 Dihydroorotate dehydrogenase pyrD 0.0116
4531 Putative ketoacyl reductase actIII 0.0116
2077 Caspase-3 CASP3 0.0116
6374 Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 0.0116
2570 Tetanus toxin tetX 0.0113
810 Heme oxygenase 1 HMOX1 0.0113
3391 Heme oxygenase 1 pbsA1 0.0113
65 Matrix metalloproteinase-9 Not Available 0.0112
4513 Pancreatic alpha-amylase AMY2A 0.0112
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0111
5590 N utilization substance protein B homolog nusB 0.0111
5588 Cell division protein FtsY TM_0570 0.0111
2838 Ribose-5-phosphate isomerase A rpiA 0.0111
2952 Ribose-5-phosphate isomerase A rpiA 0.0111
5595 Ribose-5-phosphate isomerase A rpiA 0.0111
5060 Intron-associated endonuclease 1 ITEVIR 0.0111
5593 Transferase Not Available 0.0111
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0111
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0111
2300 Lysozyme E 0.0111
3633 Lysozyme R 0.0111
5597 Lysozyme 17 0.0111
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0111
5591 Complement component C8 gamma chain C8G 0.0111
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0111
5582 Regulator of transcription; stringent starvation protein A sspA 0.0111
4238 50S ribosomal protein L4 rplD 0.0111
5578 50S ribosomal protein L4 rplD 0.0111
6173 50S ribosomal protein L4 rplD 0.0111
6219 50S ribosomal protein L4 rplD 0.0111
4695 UPF0124 protein yfiH yfiH 0.0111
5581 Beta-fructosidase bfrA 0.0111
5575 Short tail fiber protein 12 0.0111
5587 Iron(III)-binding periplasmic protein fbpA 0.0111
5580 Hexon protein PII 0.0111
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.011
4375 Glutamine synthetase 1 glnA1 0.011
5574 Invasin YPTB1668 0.011
5600 Pyruvate decarboxylase pdc 0.011
140 30S ribosomal protein S9 rpsI 0.011
6719 30S ribosomal protein S9 rpsI 0.011
6725 30S ribosomal protein S9 rpsI 0.011
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0109
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0109
4512 Cytochrome P450 3A4 CYP3A4 0.0106
4534 Cytohesin-2 CYTH2 0.0105
2688 Peptide deformylase def 0.0105
2708 Peptide deformylase def 0.0105
3004 Peptide deformylase def 0.0105
4337 Peptide deformylase def 0.0105
4338 Peptide deformylase def 0.0105
5368 Peptide deformylase def 0.0105
5371 Peptide deformylase def 0.0105
6375 Peptide deformylase def 0.0105
6378 Peptide deformylase def 0.0105
6379 Peptide deformylase def 0.0105
6776 Peptide deformylase def 0.0105
6900 Peptide deformylase def 0.0105
3140 Hemagglutinin-neuraminidase HN 0.0104
3609 Hemagglutinin-neuraminidase HN 0.0104
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0103
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0103
2548 Subtilisin Carlsberg apr 0.0101
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0098
1588 Multidrug resistance protein 1 ABCB1 0.0098
76 Nitric-oxide synthase, brain NOS1 0.0098
862 Multidrug resistance-associated protein 1 ABCC1 0.0097
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0097
3132 Tryptophan synthase alpha chain trpA 0.0096
6568 Tryptophan synthase alpha chain trpA 0.0096
3729 Citrate synthase gltA 0.0096
4575 Citrate synthase cit 0.0096
4580 Citrate synthase gltA 0.0096
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0096
5328 Prostaglandin F synthase Tb11.02.2310 0.0096
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0096
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0096
2555 Pol polyprotein pol 0.0096
3242 Pol polyprotein gag-pol 0.0096
3471 Pol polyprotein gag-pro-pol 0.0096
5256 Pol polyprotein pol 0.0096
6469 Pol polyprotein gag-pol 0.0096
6565 Pol polyprotein Not Available 0.0096
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0089
2603 Beta-lactamase II blm 0.0089
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0089
2521 Cell division protein ftsZ ftsZ 0.0089
3301 Cell division protein ftsZ ftsZ 0.0089
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0089
760 Fibroblast growth factor 1 FGF1 0.0085
3027 Streptavidin Not Available 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
3486 Fumarate hydratase class II fumC 0.0084
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0084
2942 Sialidase nanH 0.0084
3546 Sialidase nedA 0.0084
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0084
64 Neuraminidase NA 0.0084
641 Neuraminidase NA 0.0084
2676 Neuraminidase NA 0.0084
3026 Neuraminidase NA 0.0084
3519 Neuraminidase NA 0.0084
6007 Neuraminidase NA 0.0084
500 Monocarboxylate transporter 4 SLC16A3 0.0081
1024 Solute carrier family 22 member 11 SLC22A11 0.008
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.008
6143 Solute carrier family 22 member 7 SLC22A7 0.0079
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0079
2697 Uridine-cytidine kinase 2 UCK2 0.0077
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
332 Beta-lactamase blaZ 0.0077
2478 Beta-lactamase ampC 0.0077
2613 Beta-lactamase ampC 0.0077
2635 Beta-lactamase ampC 0.0077
2700 Beta-lactamase penP 0.0077
5445 Beta-lactamase blaB 0.0077
6019 Beta-lactamase SHV-7 0.0077
6701 Beta-lactamase cphA 0.0077
1123 Eosinophil cationic protein RNASE3 0.0077
857 Malate dehydrogenase, mitochondrial MDH2 0.0076
2452 Tryptophanyl-tRNA synthetase trpS 0.0076
5579 Carboxypeptidase B CPB1 0.0073
3384 Macrophage migration inhibitory factor MIF 0.0071
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0071
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0071
20 Prostaglandin G/H synthase 1 PTGS1 0.007
6142 Solute carrier family 22 member 8 SLC22A8 0.007
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0064
3947 Xanthine dehydrogenase/oxidase XDH 0.0064
1729 Solute carrier family 22 member 6 SLC22A6 0.0064
128 Adenine phosphoribosyltransferase APRT 0.006
4604 Liver carboxylesterase 1 CES1 0.0059
193 Beta-1 adrenergic receptor ADRB1 0.0057
766 Beta-2 adrenergic receptor ADRB2 0.0056
822 Aldose reductase AKR1B1 0.0055
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0054
357 Carbonic anhydrase 2 CA2 0.0053
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0051
556 Alpha-1A adrenergic receptor ADRA1A 0.005
4934 Cytochrome c-551 nirM 0.0049
5218 Cytochrome c-551 nirM 0.0049
4943 Cytochrome c6 petJ 0.0049
4936 Cytochrome c2 iso-2 Not Available 0.0049
4916 Cyanoglobin glbN 0.0049
4994 Hemoglobin-like protein HbO glbO 0.0049
4925 Cytochrome c-type protein SHP shp 0.0049
4947 Bacterial hemoglobin vhb 0.0049
4954 Soluble cytochrome b558 Not Available 0.0049
4905 Cytochrome c2 Not Available 0.0049
4939 Cytochrome c2 cycA 0.0049
4964 Cytochrome c2 cycA 0.0049
4979 Cytochrome c2 cycA 0.0049
6673 Cytochrome c2 cycA 0.0049
4907 Cytochrome c-L moxG 0.0049
6865 Cytochrome c-L moxG 0.0049
4976 Apocytochrome f petA 0.0049
6407 Apocytochrome f petA 0.0049
4904 Cytochrome c family protein GSU1996 0.0049
4915 Cytochrome c-550 psbV 0.0049
4959 Cytochrome c-550 psbV 0.0049
5216 Cytochrome c-550 psbV 0.0049
5000 HemO hemO 0.0049
4998 Hemoglobin-like protein yjbI yjbI 0.0049
644 Heme oxygenase 2 HMOX2 0.0049
4982 Heme oxygenase 2 pbsA2 0.0049
4999 Cytochrome P450 165B3 CYP165B3 0.0049
4975 Cytochrome c-556 RPA3973 0.0049
4942 Diheme cytochrome c napB napB 0.0049
4984 Neuroglobin NGB 0.0049
4937 Cytochrome oxidase subunit II rcoxA 0.0049
4971 Nonaheme cytochrome c hmcA 0.0049
4989 Cytochrome c551 peroxidase ccp 0.0049
5222 Cytochrome c551 peroxidase ccpA 0.0049
4961 Hemophore HasA hasA 0.0049
4910 Cytoglobin CYGB 0.0049
4981 Iron-starvation protein PigA pigA 0.0049
4993 Hydroxylamine oxidoreductase hao1 0.0049
4909 CooA protein cooA 0.0049
4972 P450cin cinA 0.0049
4764 Cytochrome P450 165C4 CYP165C4 0.0049
4960 Putative cytochrome P450-family protein SCO7417 0.0049
4935 Cytochrome c-554 cycA1 0.0049
4931 Cytochrome P450 167A1 CYP167A1 0.0049
4926 Heme-based aerotactic transducer hemAT hemAT 0.0049
4922 Cytochrome c, putative SO_4144 0.0049
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0049
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0049
4903 Methyl-accepting chemotaxis protein Tar4 0.0049
3093 Catalase HPII katE 0.0049
4952 Catalase/peroxidase katA 0.0049
6024 Cytochrome P450 1A1 CYP1A1 0.0048
3375 Acidic cytochrome c3 Not Available 0.0043
4385 Cytochrome c' Not Available 0.0043
4967 Cytochrome c' cycA 0.0043
5038 Cytochrome c' Not Available 0.0043
5223 Cytochrome c' cycP 0.0043
4990 PpcA ppcA 0.0043
4813 Heme oxygenase hmuO 0.0043
5769 Heme oxygenase Not Available 0.0043
2119 Cytochrome b5 CYB5A 0.0043
4289 Cytochrome P450 TT_P0059 0.0043
6262 Cytochrome P450 staP 0.0043
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0043
3570 Cytochrome P450 152A1 cypC 0.0043
4920 Peroxidase/catalase katG 0.0043
4988 Sulfite oxidase, mitochondrial SUOX 0.0043
2915 Sensor protein fixL fixL 0.0043
4944 Sensor protein fixL fixL 0.0043
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.004
4200 Cytochrome P450 1A2 CYP1A2 0.004
3670 Soluble cytochrome b562 precursor cybC 0.0039
3291 Cytochrome c-552 cycA 0.0039
4927 Cytochrome c-552 nrfA 0.0039
4938 Cytochrome c-552 cycA 0.0039
4953 Cytochrome c-552 nrfA 0.0039
5217 Cytochrome c-552 cycM 0.0039
2617 Nitric oxide synthase oxygenase nos 0.0039
2701 Nitric oxide synthase oxygenase nos 0.0039
3411 Cytochrome P450 121 cyp121 0.0039
3102 Flavohemoprotein hmp 0.0039
4969 Flavohemoprotein hmp 0.0039
4119 Cytochrome P450 2D6 CYP2D6 0.0038
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0037
2230 Catalase CAT 0.0036
3249 Catalase katA 0.0036
3625 Catalase katA 0.0036
4539 Catalase katA 0.0036
4941 Catalase katB 0.0036
4608 Putative cytochrome P450 SCO1207 0.0035
4963 Putative cytochrome P450 SCO2884 0.0035
6254 Putative cytochrome P450 SCO6998 0.0035
605 Fumarate reductase flavoprotein subunit frdA 0.0034
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0034
3673 Fumarate reductase flavoprotein subunit fccA 0.0034
4912 Fumarate reductase flavoprotein subunit ifcA 0.0034
6549 Fumarate reductase flavoprotein subunit frdA 0.0034
2972 6-deoxyerythronolide B hydroxylase eryF 0.0034
260 Cytochrome P450 51 ERG11 0.0033
761 Cytochrome P450 51 ERG11 0.0033
3163 Cytochrome P450 51 cyp51 0.0033
518 Peroxidase/catalase T katG 0.0031
693 Hemoglobin subunit beta HBB 0.0031
6268 Hydroxyacid oxidase 1 HAO1 0.0031
2298 Cytochrome P450-cam camC 0.0027
3689 Endoglucanase A celA 0.0025
5411 Slt-IIvB stxB2e 0.0025
5563 Galectin-2 LGALS2 0.0025
3009 Beta-glucanase Not Available 0.0025
5046 Ecotin eco 0.0025
5554 D-galactose-binding periplasmic protein mglB 0.0025
3741 D-galactose-binding periplasmic protein precursor mglB 0.0025
5562 Hexokinase Not Available 0.0025
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0025
3793 Aspartate ammonia-lyase aspA 0.0025
5569 Endo-1,4-beta glucanase EngF engF 0.0025
5553 Endoglucanase E1 Acel_0614 0.0025
5568 Endoglucanase C307 celC307 0.0025
4668 Laminarinase TM_0024 0.0025
4667 BH0236 protein BH0236 0.0025
1875 Pulmonary surfactant-associated protein D SFTPD 0.0025
4670 Cellulase B celB 0.0025
5570 Endoglucanase E-4 celD 0.0025
5559 Neopullulanase nplT 0.0025
4671 Endoglucanase C cenC 0.0025
3744 Endoglucanase SS precursor celS 0.0025
7 Nitric oxide synthase, inducible NOS2 0.0023
291 Nitric-oxide synthase, endothelial NOS3 0.0022
1503 Galectin-7 LGALS7 0.0022
5247 Endo-1,4-beta-xylanase Not Available 0.0022
5248 Endo-1,4-beta-xylanase xlnA 0.0022
5250 Endo-1,4-beta-xylanase xyl 0.0022
1184 Interferon beta IFNB1 0.0022
5176 YtnJ moxC 0.0022
5498 Maltoporin lamB 0.0022
5561 Maltoporin lamB 0.0022
4509 Acetoin(diacetyl) reductase budC 0.0022
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0022
2705 Dimethyl sulfoxide reductase dmsA 0.0022
4622 Amylase Not Available 0.0022
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0022
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0022
4669 Endo-1,4-beta-xylanase A xynA 0.0022
4715 Endo-1,4-beta-xylanase A xlnA 0.0022
5560 Endo-1,4-beta-xylanase A xynA 0.0022
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.002
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.002
2606 Neopullulanase 2 tvaII 0.002
4811 Amylosucrase ams 0.002
2531 Alpha-amylase amyE 0.002
2948 Alpha-amylase amy 0.002
3169 Alpha-amylase Not Available 0.002
2541 Neopullulanase 1 tvaI 0.002
3747 Cellulase B precursor celB 0.002
4819 Hydrolase Not Available 0.002
5249 Hydrolase Not Available 0.002
5436 Hydrolase Not Available 0.002
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.002
3091 Maltodextrin phosphorylase malP 0.002
3225 Shiga toxin B-chain stxB 0.0019
4666 Fucose-binding lectin PA-IIL lecB 0.0019
4830 Aldose 1-epimerase galM 0.0019
2372 Bifunctional tail protein 9 0.0019
2826 Glucose--fructose oxidoreductase gfo 0.0019
3365 Beta-amylase spoII 0.0019
1881 Hexokinase-1 HK1 0.0019
6106 Cytochrome P450 2C18 CYP2C18 0.0018
6614 Lactase-like protein LCTL 0.0018
1675 Glucokinase GCK 0.0018
4662 Glucokinase glk 0.0018
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0018
2508 Cyclomaltodextrin glucanotransferase cgt 0.0018
2523 Cyclomaltodextrin glucanotransferase cgt 0.0018
3207 Cyclomaltodextrin glucanotransferase amyA 0.0018
3668 Maltose-binding periplasmic protein precursor malE 0.0017
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0017
4272 POSSIBLE CELLULASE CELA1 celA1 0.0017
2440 Endoglucanase F celCCF 0.0016
290 Prostaglandin G/H synthase 2 PTGS2 0.0016
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0016
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
2245 Xylose isomerase xylA 0.0015
2253 Xylose isomerase xylA 0.0015
2260 Xylose isomerase xylA 0.0015
2431 Xylose isomerase xylA 0.0015
2252 Endoglucanase 5A cel5A 0.0015
6030 Cytochrome P450 2B6 CYP2B6 0.0014
10 Glycogen phosphorylase, liver form PYGL 0.0014
4924 Cytochrome P450 2C8 CYP2C8 0.0013
1152 Glycogen phosphorylase, muscle form PYGM 0.0011
↑