Identification | |||||||||||||||||||||||
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Name | Pivampicillin | ||||||||||||||||||||||
Accession Number | DB01604 | ||||||||||||||||||||||
Type | small molecule | ||||||||||||||||||||||
Description | Pivalate ester analog of ampicillin. | ||||||||||||||||||||||
Structure |
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Categories (*) | |||||||||||||||||||||||
Molecular Weight | 463.547 | ||||||||||||||||||||||
Groups | approved | ||||||||||||||||||||||
Monoisotopic Weight | 463.177706365 | ||||||||||||||||||||||
Pharmacology | |||||||||||||||||||||||
Indication | or the treatment of respiratory tract infections (including acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia); ear, nose and throat infections; gynecological infections; urinary tract infections (including acute uncomplicated gonococcal urethritis) when caused by non penicillinase-producing susceptible strains of the following organisms: gram-positive organisms, e.g., streptococci, pneumococci and staphylococci; gram-negative organisms, e.g., H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis. | ||||||||||||||||||||||
Mechanism of action | Ampicillin (the active metabolite of pivampicillin) has a bactericidal action resulting from inhibition of cell wall mucopeptide biosynthesis. | ||||||||||||||||||||||
Absorption | Absorbed following oral administration. | ||||||||||||||||||||||
Protein binding | Not Available | ||||||||||||||||||||||
Biotransformation | Not Available | ||||||||||||||||||||||
Route of elimination | Not Available | ||||||||||||||||||||||
Toxicity | Not Available | ||||||||||||||||||||||
Affected organisms |
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Interactions | |||||||||||||||||||||||
Drug Interactions |
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Food Interactions |
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Penicillin-binding proteins 1A/1B | |
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Name | Penicillin-binding proteins 1A/1B |
Gene Name | pbpA |
Pharmacological action | yes |
Actions | inhibitor |
References |
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DTHybrid score | 0.7406 |