| Partner ID | 6548 | ||||||||
| Name | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | ||||||||
| Synonyms | 8774 | ||||||||
| Gene name | ispH | ||||||||
| General function | Lipid transport and metabolism | ||||||||
| Specific function | Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth | ||||||||
| Gene sequence |
+ ...
Not Available |
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| Protein sequence |
+ ...
MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD |
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| GO Classification |
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| See more information at → www.drugbank.ca | |||||||||
| Id | Name |
|---|---|
| DB01785 | Dimethylallyl Diphosphate |
| DB04714 | ISOPENTENYL PYROPHOSPHATE |
| Id | Name |
|---|---|
| DB00282 | Pamidronate |
| DB00399 | Zoledronate |
| DB00630 | Alendronate |
| DB00710 | Ibandronate |
| DB00884 | Risedronate |
| DB01785 | Dimethylallyl Diphosphate |
| DB02508 | Isopentyl Pyrophosphate |
| DB02552 | Geranyl Diphosphate |
| DB04695 | FARNESYL THIOPYROPHOSPHATE |
| DB04714 | ISOPENTENYL PYROPHOSPHATE |
| DB06830 | (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) |
| DB06931 | (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) |
| DB07221 | (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM |
| DB07404 | (1-HYDROXY-1-PHOSPHONO-2-[1,1';3',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID |
| DB07409 | (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID |
| DB07410 | [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID |
| DB07426 | [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) |
| DB07780 | FARNESYL DIPHOSPHATE |
| DB07841 | GERANYLGERANYL DIPHOSPHATE |
| DB07873 | (1-HYDROXYDODECANE-1,1-DIYL)BIS(PHOSPHONIC ACID) |
| DB08529 | (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) |