DT-Web

DB04695 - FARNESYL THIOPYROPHOSPHATE


Identification
Name FARNESYL THIOPYROPHOSPHATE
Accession Number DB04695
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 398.392
Groups experimental
Monoisotopic Weight 398.108182342
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Undecaprenyl pyrophosphate synthetase
Name Undecaprenyl pyrophosphate synthetase
Gene Name uppS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.723
Geranylgeranyl pyrophosphate synthetase
Name Geranylgeranyl pyrophosphate synthetase
Gene Name GGPS1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6407
Mevalonate kinase
Name Mevalonate kinase
Gene Name MVK
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8231
Dehydrosqualene synthase
Name Dehydrosqualene synthase
Gene Name crtM
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.9593

Predictions


Id Partner name Gene Name Score
853 Farnesyl pyrophosphate synthetase FDPS 0.1671
6548 4-hydroxy-3-methylbut-2-enyl diphosphate reductase ispH 0.1019
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.0745
6576 Geranylgeranyl transferase type-2 subunit beta RABGGTB 0.0647
6575 Geranylgeranyl transferase type-2 subunit alpha RABGGTA 0.0647
4128 Protein farnesyltransferase subunit beta FNTB 0.0539
6595 Lantibiotic nisin-Z nisZ 0.0533
4129 Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit FNTA 0.0529
6574 GTPase KRas KRAS 0.0427
3188 IspD/ispF bifunctional enzyme [Includes: 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase ispDF 0.0282
1994 Geranylgeranyl transferase type-1 subunit beta PGGT1B 0.0259
6540 Prenyltransferase Not Available 0.0244
862 Multidrug resistance-associated protein 1 ABCC1 0.0234
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0226
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