DT-Web

DB03846 - 5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate


Identification
Name 5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate
Accession Number DB03846 (EXPT00248)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 339.2158
Groups experimental
Monoisotopic Weight 339.059341632
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Thymidylate kinase
Name Thymidylate kinase
Gene Name tmk
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6111

Predictions


Id Partner name Gene Name Score
2254 Thymidylate kinase DTYMK 0.6111
3522 Thymidylate kinase tmk 0.6111
509 Thymidine kinase TK 0.0844
570 Thymidine kinase TK 0.0844
2559 Thymidine kinase TK 0.0844
3430 Thymidine kinase tdk 0.0844
3518 Thymidine kinase TK 0.0844
5301 Thymidine kinase tdk 0.0844
5771 Thymidine kinase ORF36 0.0844
7009 Thymidine kinase ORF36 0.0844
2632 Adenylosuccinate synthetase purA 0.0459
3323 Adenylosuccinate synthetase purA 0.0459
3975 Adenylosuccinate synthetase ADSS 0.0459
4598 Adenylosuccinate synthetase Adss 0.0459
6817 Adenylosuccinate synthetase purA 0.0459
2756 Geranyltranstransferase ispA 0.0458
2434 NH(3)-dependent NAD(+) synthetase nadE 0.044
2910 NH(3)-dependent NAD(+) synthetase nadE 0.044
3217 NH(3)-dependent NAD(+) synthetase nadE 0.044
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0415
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0415
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0415
3481 Glucose-1-phosphate thymidylyltransferase 2 rmlA2 0.0392
3755 Nucleoside-specific channel-forming protein tsx precursor tsx 0.0385
4275 PCZA361.16 Not Available 0.0344
4276 DNA polymerase III subunit epsilon dnaQ 0.0344
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.034
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.034
3299 DNA primase/helicase 4 0.0339
2427 Ferrichrome-iron receptor fhuA 0.0318
3244 Ribonucleoside-diphosphate reductase 2 alpha subunit nrdE 0.0313
1353 DNA topoisomerase 1 TOP1 0.0301
3552 DNA topoisomerase 1 topA 0.0301
2633 Anaerobic ribonucleoside-triphosphate reductase NRDD 0.0294
2257 Uridine phosphorylase udp 0.0274
5132 Uridine phosphorylase udp 0.0274
2320 Thymidine kinase, cytosolic TK1 0.0266
6171 Solute carrier family 28 member 3 SLC28A3 0.023
24 Thymidylate synthase TMP1 0.0179
359 Thymidylate synthase TYMS 0.0179
2626 Thymidylate synthase thyA 0.0179
2729 Thymidylate synthase thyA 0.0179
5352 Thymidylate synthase THYA 0.0179
6145 Solute carrier family 22 member 1 SLC22A1 0.0127
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