DT-Web

DB03674 - Methyl Mercury Ion


Identification
Name Methyl Mercury Ion
Accession Number DB03674 (EXPT01739)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 215.62
Groups experimental
Monoisotopic Weight 216.9941007
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Carbonic anhydrase 2
Name Carbonic anhydrase 2
Gene Name CA2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.6612
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Name Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Gene Name MGAT1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
UPF0234 protein HI1034
Name UPF0234 protein HI1034
Gene Name HI_1034
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9159
M-phase inducer phosphatase 2
Name M-phase inducer phosphatase 2
Gene Name CDC25B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7808

Predictions


Id Partner name Gene Name Score
295 Carbonic anhydrase 1 CA1 0.0835
1434 Protein DJ-1 PARK7 0.0505
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0505
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0505
4341 Beta crystallin B1 CRYBB1 0.0505
4340 Hypothetical conserved protein GK2698 0.0505
6484 Hypothetical conserved protein TT_C0834 0.0505
4339 Sucrose phosphorylase sucP 0.0505
5367 Peroxiredoxin prx 0.0471
5366 Sugar-phosphate isomerase TM_1080 0.0471
5365 Metallo beta-lactamase blaVIM-2 0.0471
5369 Golgi-associated plant pathogenesis-related protein 1 GLIPR2 0.0471
4699 Methylaspartate ammonia-lyase Not Available 0.0471
592 Carbonic anhydrase 4 CA4 0.0461
3421 Hydroxyethylthiazole kinase thiM 0.044
687 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 0.0435
3858 Cathepsin L CTSL1 0.0411
3596 Deoxynucleotide monophosphate kinase 1 0.041
4343 Alpha-glucosidase aglA 0.0405
2664 S-ribosylhomocysteine lyase luxS 0.0357
2725 S-ribosylhomocysteine lyase luxS 0.0357
2840 Beta-lactamase IMP-1 Not Available 0.0353
2385 Penicillin acylase Not Available 0.0333
3873 Prolyl endopeptidase PREP 0.0325
6928 Prolyl endopeptidase Not Available 0.0325
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0307
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0307
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0307
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0307
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0209
3623 Divalent-cation tolerance protein cutA cutA 0.0206
466 Solute carrier family 12 member 3 SLC12A3 0.0202
2240 Cell division protein kinase 2 CDK2 0.0189
558 Solute carrier family 12 member 1 SLC12A1 0.0157
6126 Carbonic anhydrase 7 CA7 0.0154
3384 Macrophage migration inhibitory factor MIF 0.0132
1729 Solute carrier family 22 member 6 SLC22A6 0.0125
3007 Carbonic anhydrase 12 CA12 0.0117
4205 Carbonic anhydrase 9 CA9 0.0117
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0105
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0073
3627 UPF0190 protein yedY yedY 0.0067
4512 Cytochrome P450 3A4 CYP3A4 0.0067
1392 Catenin beta-1 CTNNB1 0.0067
3352 Structural polyprotein Not Available 0.0067
3628 Structural polyprotein Not Available 0.0067
4892 Structural polyprotein Not Available 0.0067
1405 Thiopurine S-methyltransferase TPMT 0.0066
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0061
6131 Carbonic anhydrase 14 CA14 0.0052
6122 Carbonic anhydrase 3 CA3 0.0051
4757 Cytochrome P450 2C9 CYP2C9 0.0049
310 Solute carrier family 12 member 2 SLC12A2 0.0046
365 Dihydrofolate reductase DHFR 0.0046
2381 Dihydrofolate reductase DFR1 0.0046
2833 Dihydrofolate reductase Not Available 0.0046
2931 Dihydrofolate reductase folA 0.0046
3544 Dihydrofolate reductase folA 0.0046
3682 Dihydrofolate reductase folA 0.0046
6642 Dihydrofolate reductase folA 0.0046
6756 Dihydrofolate reductase dfrA 0.0046
315 Arginase-1 ARG1 0.004
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0036
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0033
1025 Aquaporin-1 AQP1 0.0032
3426 Glutamine synthetase glnA 0.0028
3987 Glutamine synthetase GLUL 0.0028
6016 Cytochrome P450 2C19 CYP2C19 0.0028
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0028
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0025
1024 Solute carrier family 22 member 11 SLC22A11 0.0022
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.002
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.002
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0017
6013 Cytochrome P450 2E1 CYP2E1 0.0017
997 Protein kinase C beta type PRKCB 0.0015
2408 Tyrosine-protein kinase SYK SYK 0.0014
118 Organic cation/carnitine transporter 2 SLC22A5 0.0013
1970 Protein kinase C alpha type PRKCA 0.0013
6142 Solute carrier family 22 member 8 SLC22A8 0.0013
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0012
634 Squalene monooxygenase SQLE 0.0012
7196 Squalene monooxygenase ERG1 0.0012
587 Serum albumin ALB 0.0012
2236 Casein kinase II subunit alpha CSNK2A1 0.0011
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.001
4119 Cytochrome P450 2D6 CYP2D6 0.001
6130 Carbonic anhydrase 13 CA13 0.0009
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0009
6127 Carbonic anhydrase-related protein CA8 0.0009
6129 Carbonic anhydrase-related protein 11 CA11 0.0009
6128 Carbonic anhydrase-related protein 10 CA10 0.0009
6135 Sodium channel subunit beta-4 SCN4B 0.0009
6133 Sodium channel subunit beta-2 SCN2B 0.0009
6134 Sodium channel subunit beta-3 SCN3B 0.0009
6132 Sodium channel subunit beta-1 SCN1B 0.0009
4037 Hypothetical protein GPX1 0.0008
4297 Hypothetical protein SP_1951 0.0008
4521 Hypothetical protein BC_2969 0.0008
4540 Hypothetical protein TM_1070 0.0008
4555 Hypothetical protein MT1739 0.0008
4569 Hypothetical protein mshD 0.0008
4578 Hypothetical protein PA3270 0.0008
4747 Hypothetical protein PA3967 0.0008
5177 Hypothetical protein TM_0096 0.0008
5194 Hypothetical protein PA1204 0.0008
5240 Hypothetical protein Rv2991 0.0008
5370 Hypothetical protein TM_1158 0.0008
5710 Hypothetical protein Tb927.5.1360 0.0008
4527 Putative hydrolase ycdX ycdX 0.0008
4536 Transcriptional regulator, IclR family TM_0065 0.0008
2501 Protein ygbM ygbM 0.0008
4545 Molybdopterin-converting factor subunit 2 moaE 0.0008
4522 Arginine N-succinyltransferase subunit alpha astA 0.0008
4106 Guanylate kinase GUK1 0.0008
4516 Guanylate kinase gmk 0.0008
4538 Hypothetical protein VC1899 VC_1899 0.0008
4529 Oxalate decarboxylase oxdC oxdC 0.0008
4514 Citrate lyase beta subunit-like protein citE 0.0008
4781 Citrate lyase beta subunit-like protein DR_1240 0.0008
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0008
4524 Mannose-6-phosphate isomerase yvyI 0.0008
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0008
4547 Iron binding protein FbpA fbpA 0.0008
4548 Gyrase B gyrB 0.0008
4546 Aminotransferase, putative TM_1131 0.0008
658 Para-aminobenzoate synthase component 1 pabB 0.0008
4515 Peripheral plasma membrane protein CASK CASK 0.0008
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0008
4496 C-terminal-binding protein 1 CTBP1 0.0008
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0007
4517 Probable butyrate kinase 2 buk2 0.0007
3261 Signal recognition particle protein ffh 0.0007
4528 Phenazine biosynthesis protein PhzD phzD1 0.0007
4533 Glyoxalase family protein BC_1747 0.0007
56 Delta-aminolevulinic acid dehydratase ALAD 0.0007
2356 Delta-aminolevulinic acid dehydratase hemB 0.0007
3613 Delta-aminolevulinic acid dehydratase hemB 0.0007
3674 Delta-aminolevulinic acid dehydratase hemB 0.0007
3759 Glutathione S-transferase gst 0.0007
4541 Glutathione S-transferase GST 0.0007
4542 Glutaminase 1 glsA1 0.0007
4544 Glutaminase 1 glsA1 0.0007
2929 (S)-2-haloacid dehalogenase dhlB 0.0007
2995 (S)-2-haloacid dehalogenase Not Available 0.0007
3237 Beta-lactamase OXA-2 bla 0.0007
4532 Gephyrin GPHN 0.0007
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0007
2230 Catalase CAT 0.0007
3249 Catalase katA 0.0007
3625 Catalase katA 0.0007
4539 Catalase katA 0.0007
4941 Catalase katB 0.0007
4531 Putative ketoacyl reductase actIII 0.0007
2775 Dihydroorotate dehydrogenase pyrD 0.0007
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0007
3467 Methylglyoxal synthase mgsA 0.0007
3583 6-phosphogluconolactonase pgl 0.0007
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0006
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0006
2688 Peptide deformylase def 0.0006
2708 Peptide deformylase def 0.0006
3004 Peptide deformylase def 0.0006
4337 Peptide deformylase def 0.0006
4338 Peptide deformylase def 0.0006
5368 Peptide deformylase def 0.0006
5371 Peptide deformylase def 0.0006
6375 Peptide deformylase def 0.0006
6378 Peptide deformylase def 0.0006
6379 Peptide deformylase def 0.0006
6776 Peptide deformylase def 0.0006
6900 Peptide deformylase def 0.0006
4534 Cytohesin-2 CYTH2 0.0006
6024 Cytochrome P450 1A1 CYP1A1 0.0006
2548 Subtilisin Carlsberg apr 0.0006
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0006
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0006
6020 Aldehyde oxidase AOX1 0.0005
3939 Amine oxidase [flavin-containing] B MAOB 0.0005
760 Fibroblast growth factor 1 FGF1 0.0005
810 Heme oxygenase 1 HMOX1 0.0005
3391 Heme oxygenase 1 pbsA1 0.0005
3027 Streptavidin Not Available 0.0005
3941 Amine oxidase [flavin-containing] A MAOA 0.0005
500 Monocarboxylate transporter 4 SLC16A3 0.0005
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0004
76 Nitric-oxide synthase, brain NOS1 0.0004
5682 Ribonuclease pancreatic RNASE1 0.0004
↑