DT-Web

3-ketoacyl-CoA thiolase


Partner ID 6765
Name 3-ketoacyl-CoA thiolase
Synonyms 8995
Gene name fadA
General function Lipid transport and metabolism
Specific function Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed (By similarity)
Gene sequence + ...

ATGATTTACGAAGGTAAAGCCATCACGGTTACGGCTCTTGAAAGTGGCATCGTCGAACTGAAGTTCGACCTCAAGGGTGAGTCCGTCAACAAATTCAACCGTCTAACCCTGAACGAATTGCGTCAGGCGGTAGATGCGATCAAGGCCGACGCTTCGGTCAAGGGTGTCATCGTTTCCAGCGGTAAAGACGTATTTATCGTCGGCGCCGACATCACCGAATTCGTCGAAAACTTCAAGTTGCCGGATGCCGAGCTGATTGCTGGCAACCTCGAAGCCAACAAGATCTTCAGCGATTTTGAAGACCTCAATGTACCCACCGTCGCAGCCATCAATGGCATCGCGTTGGGCGGTGGCCTGGAAATGTGCCTGGCAGCCGACTTCCGGGTCATGGCCGACAGCGCCAAGATCGGCCTGCCGGAAGTCAAACTGGGCATCTACCCGGGCTTTGGCGGCACCGTACGTCTGCCACGCCTGATCGGTGTTGATAACGCGGTTGAGTGGATTGCCTCCGGCAAGGAAAACCGCGCAGAAGACGCTCTGAAAGTCAGCGCCGTTGATGCTGTTGTCACTGCTGACAAGCTGGGCGCAGCTGCCCTGGACCTGATCAAGCGCGCCATCAGTGGCGAACTGGACTACAAGGCCAAGCGTCAGCCGAAGCTGGAAAAACTCAAGCTCAACGCTATCGAACAAATGATGGCTTTCGAAACCGCCAAAGGTTTCGTGGCTGGCCAGGCCGGCCCGAACTACCCGGCCCCGGTTGAAGCGATCAAGACCATCCAGAAAGCCGCGAACTTCGGTCGTGACAAAGCCCTGGAAGTGGAAGCTGCAGGTTTCGCCAAGCTGGCCAAAACCAGCGCCTCGAACTGCCTGATCGGCCTGTTCCTGAACGATCAGGAACTGAAGAAAAAGGCCAAGGTCTACGACAAGATCGCCAAAGACGTGAAGCAGGCCGCCGTTCTGGGCGCCGGCATCATGGGTGGCGGCATTGCCTATCAGTCGGCGTCCAAAGGCACGCCGATCCTGATGAAGGACATCAACGAGCACGGTATCGAGCAGGGCCTGGCTGAAGCCGCCAAGCTGCTGGTAGGTCGCGTTGATAAAGGTCGCATGACCCCGGCAAAAATGGCTGAAGTGCTGAACGGCATTCGTCCTACTCTGTCCTACGGCGATTTCGGCAACGTCGACCTGGTGGTCGAAGCGGTTGTCGAGAACCCGAAGGTCAAGCAGGCCGTGTTGGCGGAAGTGGAAAACCACGTTCGCGAAGACGCCATCCTCGCTTCCAACACCTCGACCATTTCCATCAGCTTGCTGGCCAAGGCCCTCAAGCGTCCGGAAAACTTCGTCGGCATGCACTTCTTCAACCCGGTACACATGATGCCGCTGGTTGAAGTGATCCGTGGCGAGAAGTCCAGCGACCTGGCCGTGGCCACCACCGTTGCCTACGCCAAGAAAATGGGCAAGAACCCGATCGTGGTCAACGACTGCCCGGGCTTCCTGGTCAACCGCGTACTGTTCCCGTACTTCGGCGGTTTCGCCAAGCTGGTCAGCGCCGGTGTCGACTTTGTGCGTATCGACAAAGTGATGGAAAAATTCGGCTGGCCGATGGGCCCGGCGTACCTGATGGACGTGGTCGGTATCGACACTGGCCACCACGGTCGCGACGTGATGGCTGAAGGCTTCCCGGACCGCATGAAAGACGACCGCCGCTCGGCGATCGATGCGCTGTACGAGGCCAAGCGCCTGGGTCAGAAGAACGGCAAGGGCTTCTACGCCTACGAGGCTGACAAAAAGGGCAAGCAGAAGAAACTGGTTGATTCGAGCGTGCTTGAAGTGCTCAAACCAATCGTTTACGAGCAGCGCGACGTGACCGACGAAGACATCATCAACTGGATGATGATCCCGCTGTGCCTGGAAACCGTGCGTTGCCTGGAAGACGGTATCGTTGAAACTGCAGCCGAGGCCGATATGGGCCTGGTCTACGGCATTGGCTTCCCGCTGTTCCGTGGTGGCGCGCTGCGCTACATCGATTCGATCGGTGTTGCAGAGTTCGTCGCCCTGGCCGATCAGTACGCTGAACTGGGCGCGCTGTACCACCCGACTGCGAAGCTGCGTGAGATGGCCAAGAACGGCCAGAGCTTCTTCGGTTAA
Protein sequence + ...

MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVSMMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGISREQQDAFAVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFERV
GO Classification Not Available
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL

Associated as Prediction

Id Name
DB01097 Leflunomide
DB01117 Atovaquone
DB01743 Pyoverdine-Chromophore
DB02262 Orotic Acid
DB02613 Decylamine-N,N-Dimethyl-N-Oxide
DB03247 Riboflavin Monophosphate
DB03480 Brequinar Analog
DB03523 6-Fluoro-2-(2'-Fluoro-1,1'-Biphenyl-4-Yl)-3-Methylquinoline-4-Carboxylic Acid
DB03805 Antiproliferative Agent A771726
DB04147 Lauryl Dimethylamine-N-Oxide
DB04281 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone
DB04583 5-(AMINOCARBONYL)-1,1':4',1''-TERPHENYL-3-CARBOXYLICACID
DB07443 (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide
DB07559 (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07561 (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07646 UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
DB07975 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID
DB07976 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID
DB07977 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID
DB07978 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID
DB08006 N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08008 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08169 (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide
DB08172 (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL
DB08880 Teriflunomide
↑