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Fatty acid oxidation complex subunit alpha


Partner ID 6764
Name Fatty acid oxidation complex subunit alpha
Synonyms 8992
Gene name fadB
General function Lipid transport and metabolism
Specific function Catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities (By similarity)
Gene sequence + ...

ATGATTTACGAAGGTAAAGCCATCACGGTTACGGCTCTTGAAAGTGGCATCGTCGAACTGAAGTTCGACCTCAAGGGTGAGTCCGTCAACAAATTCAACCGTCTAACCCTGAACGAATTGCGTCAGGCGGTAGATGCGATCAAGGCCGACGCTTCGGTCAAGGGTGTCATCGTTTCCAGCGGTAAAGACGTATTTATCGTCGGCGCCGACATCACCGAATTCGTCGAAAACTTCAAGTTGCCGGATGCCGAGCTGATTGCTGGCAACCTCGAAGCCAACAAGATCTTCAGCGATTTTGAAGACCTCAATGTACCCACCGTCGCAGCCATCAATGGCATCGCGTTGGGCGGTGGCCTGGAAATGTGCCTGGCAGCCGACTTCCGGGTCATGGCCGACAGCGCCAAGATCGGCCTGCCGGAAGTCAAACTGGGCATCTACCCGGGCTTTGGCGGCACCGTACGTCTGCCACGCCTGATCGGTGTTGATAACGCGGTTGAGTGGATTGCCTCCGGCAAGGAAAACCGCGCAGAAGACGCTCTGAAAGTCAGCGCCGTTGATGCTGTTGTCACTGCTGACAAGCTGGGCGCAGCTGCCCTGGACCTGATCAAGCGCGCCATCAGTGGCGAACTGGACTACAAGGCCAAGCGTCAGCCGAAGCTGGAAAAACTCAAGCTCAACGCTATCGAACAAATGATGGCTTTCGAAACCGCCAAAGGTTTCGTGGCTGGCCAGGCCGGCCCGAACTACCCGGCCCCGGTTGAAGCGATCAAGACCATCCAGAAAGCCGCGAACTTCGGTCGTGACAAAGCCCTGGAAGTGGAAGCTGCAGGTTTCGCCAAGCTGGCCAAAACCAGCGCCTCGAACTGCCTGATCGGCCTGTTCCTGAACGATCAGGAACTGAAGAAAAAGGCCAAGGTCTACGACAAGATCGCCAAAGACGTGAAGCAGGCCGCCGTTCTGGGCGCCGGCATCATGGGTGGCGGCATTGCCTATCAGTCGGCGTCCAAAGGCACGCCGATCCTGATGAAGGACATCAACGAGCACGGTATCGAGCAGGGCCTGGCTGAAGCCGCCAAGCTGCTGGTAGGTCGCGTTGATAAAGGTCGCATGACCCCGGCAAAAATGGCTGAAGTGCTGAACGGCATTCGTCCTACTCTGTCCTACGGCGATTTCGGCAACGTCGACCTGGTGGTCGAAGCGGTTGTCGAGAACCCGAAGGTCAAGCAGGCCGTGTTGGCGGAAGTGGAAAACCACGTTCGCGAAGACGCCATCCTCGCTTCCAACACCTCGACCATTTCCATCAGCTTGCTGGCCAAGGCCCTCAAGCGTCCGGAAAACTTCGTCGGCATGCACTTCTTCAACCCGGTACACATGATGCCGCTGGTTGAAGTGATCCGTGGCGAGAAGTCCAGCGACCTGGCCGTGGCCACCACCGTTGCCTACGCCAAGAAAATGGGCAAGAACCCGATCGTGGTCAACGACTGCCCGGGCTTCCTGGTCAACCGCGTACTGTTCCCGTACTTCGGCGGTTTCGCCAAGCTGGTCAGCGCCGGTGTCGACTTTGTGCGTATCGACAAAGTGATGGAAAAATTCGGCTGGCCGATGGGCCCGGCGTACCTGATGGACGTGGTCGGTATCGACACTGGCCACCACGGTCGCGACGTGATGGCTGAAGGCTTCCCGGACCGCATGAAAGACGACCGCCGCTCGGCGATCGATGCGCTGTACGAGGCCAAGCGCCTGGGTCAGAAGAACGGCAAGGGCTTCTACGCCTACGAGGCTGACAAAAAGGGCAAGCAGAAGAAACTGGTTGATTCGAGCGTGCTTGAAGTGCTCAAACCAATCGTTTACGAGCAGCGCGACGTGACCGACGAAGACATCATCAACTGGATGATGATCCCGCTGTGCCTGGAAACCGTGCGTTGCCTGGAAGACGGTATCGTTGAAACTGCAGCCGAGGCCGATATGGGCCTGGTCTACGGCATTGGCTTCCCGCTGTTCCGTGGTGGCGCGCTGCGCTACATCGATTCGATCGGTGTTGCAGAGTTCGTCGCCCTGGCCGATCAGTACGCTGAACTGGGCGCGCTGTACCACCCGACTGCGAAGCTGCGTGAGATGGCCAAGAACGGCCAGAGCTTCTTCGGTTAA
Protein sequence + ...

MIYEGKAITVTALESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISGELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDKIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQKKLVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVALADQYAELGALYHPTAKLREMAKNGQSFFG
GO Classification
function
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-NH group of donors
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
process
fatty acid metabolism
physiological process
metabolism
cellular metabolism
organic acid metabolism
carboxylic acid metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL

Associated as Prediction

Id Name
DB01097 Leflunomide
DB01117 Atovaquone
DB01743 Pyoverdine-Chromophore
DB02262 Orotic Acid
DB02613 Decylamine-N,N-Dimethyl-N-Oxide
DB03247 Riboflavin Monophosphate
DB03480 Brequinar Analog
DB03523 6-Fluoro-2-(2'-Fluoro-1,1'-Biphenyl-4-Yl)-3-Methylquinoline-4-Carboxylic Acid
DB03805 Antiproliferative Agent A771726
DB04147 Lauryl Dimethylamine-N-Oxide
DB04281 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone
DB04583 5-(AMINOCARBONYL)-1,1':4',1''-TERPHENYL-3-CARBOXYLICACID
DB07443 (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide
DB07559 (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07561 (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07646 UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
DB07975 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID
DB07976 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID
DB07977 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID
DB07978 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID
DB08006 N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08008 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08169 (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide
DB08172 (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL
DB08880 Teriflunomide
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