| Name |
Hyaluronate lyase |
| Synonyms |
4369 |
| Gene name |
hylB |
| General function |
Involved in hyaluronidase activity |
| Specific function |
Cleaves hyaluronate chains at a beta-D-GalNAc- (1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D- glucosamine |
| Gene sequence |
+ ...
ATGAAACAAGTAGTAGATAATCAAACTCAAAATAAGGAGCTGGTGAAAAACGGAGATTTTAATCAAACTAACCCTGTATCTGGAAGCTGGTCACATACAAGCGCTAGGGAATGGTCTGCTTGGATTGATAAAGGAAATACTGCTGATAAATCACCTATTATCCAACGTACCGAACAAGGCCAAGTAAGTCTATCCAGCGACAAAGGCTTTAGAGGTGCTGTAACACAAAAAGTGAACATTGATCCCACTAAAAAATATGAGGTTAAGTTTGATATTGAAACAAGTAACAAGGCTGGACAAGCTTTCCTTCGTATTATGGAGAAAAAAGACAACAATACGCGACTTTGGCTTTCTGAGATGACCAGCGGTACTACTAACAAACATACCTTAACAAAGATATATAACCCAAAGTTAAATGTCTCCGAGGTGACACTTGAACTTTATTATGAAAAAGGAACTGGTTTTGTTACTTTTGATAATATATCAATGAAAGCAAAAGGCCCTAAAGACTCAGAGCATCCACAACCCGTCACAACACAAATTGAAAAAAGCGTTAATACGGCTTTAAACAAAAATTACGTTTTTAATAAAGCTGACTACCAATACACTCTAACCAATCCGTCTCTTGGGAAAATTGTTGGGGGAATATTGTATCCAAACGCTACTGGTTCAACAACTGTTAAAATATCTGATAAATCTGGGAAAATAATTAAAGAAGTACCGTTATCAGTTACAGGTTCACCAGAAGATAACTTTACAAAACTCCTCGACAAATGGAACGACGTGACTATTGGTAATTATGTTTACGATACTAATGATTCGAACATGCAAAAGCTTACTCAGAAATTAGATGAAACTAACGGCAAAAACATCGAAGCTATCAAACTGGATTCTAATCGCACTTTCCTTTGGAAAGATTTAGATAATCTCAATAATTCAGCACAGTTAACCGCTACTTATCGTCGTTTGGAAGATTTAGCTAAACAAATCACCAATCCACACTCTACTATTTACAAAAATGAAAAAGCTATTCGTACTGTAAAAGAGAGTCTGGCTTGGCTTCATCAGAACTTCTACAATGTTAATAAAGATATAGAAGGCTCTGCCAATTGGTGGGATTTTGAAATCGGTGTTCCTCGCTCAATTACAGGTACCCTATCTCTCATGAATAACTACTTCACTGACGCTGAAATAAAAACTTATACCGACCCAATTGAACACTTTGTTCCTGATGCAGAATATTTCCGTAAAACGCTTGTCAATCCATTTAAAGCCCTTGGTGGTAATCTAGTAGATATGGGGCGCGTTAAAATCATTGAAGGTTTACTTCGTAAAGACAATACTATTATCGAAAAAACTTCTCATTCTCTAAAAAATCTTTTTACTACTGCTACTAAAGCTGAAGGCTTCTATGCTGACGGTTCTTACATCGACCATACAAATGTTGCTTATACTGGCGCCTATGGTAATGTTCTGATAGATGGTTTGACACAATTGCTGCCTATCATTCAAGAAACTGACTATAAAATCTCTAATCAAGAACTTGATATGGTTTATAAATGGATTAATCAATCATTTTTACCTTTAATTGTAAAAGGTGAGTTAATGGATATGAGTCGTGGACGCTCAATTAGTAGAGAGGCAGCTTCTTCGCATGCGGCTGCAGTTGAAGTTCTCAGAGGTTTCCTCAGATTGGCTAACATGTCTAATGAAGAGCGAAACTTAGACCTCAAATCAACTATTAAAGCGATTATCACTTCAAATAAATTCTACAATGTCTTCAATAACCTCAAATCGTATTCCGATATTGCCAACATGAATAAGCTGCTTAATGACAGTACAGTCGCTACTAAACCTTTAAAAAGTAATTTATCAACCTTTAATAGCATGGACCGCTTAGCTTATTATAATGCCAAGAAAGACTTTGGTTTCGCGCTTTCATTACATTCTAAACGTACCCTCAACTATGAAGGAATGAATGATGAAAATACACGTGGTTGGTATACCGGAGATGGTATGTTCTATATTTATAATAGTGATCAATCTCATTATAGTAATCATTTGGGGCCAACCGTCAATCCTTATAAAATGGCTGGAACAACTGAAAAAGATGCTAAGCGTGAAGATACCACTAAGGAATTCATGAGCAAACATAGCAAAGACGCTAAAGAAAAAACCGGTCAAGTTACAGGAACATCTGACTTTGTTGGTTCCGTCAAACTTAATGATCACTTTGCTCTTGCCGCTATGGATTTTACTAACTGGGATCGCACCTTAACAGCACAAAAAGGTTGGGTTATCTTAAATGATAAGATTGTCTTTTTAGGTAGCAACATCAAGAATACTAACGGCATTGGAAATGTTTCTACAACAATTGATCAACGAAAAGACGATTCTAAAACACCTTATACTACATACGTCAATGGAAAAACTATTGATTTAAAACAAGCAAGTTCTCAACAATTTACAGATACAAAAAGTGTCTTTTTAGAATCAAAAGAACCTGGTCGCAATATTGGTTATATCTTCTTTAAAAATAGCACTATTGATATTGAACGCAAAGAGCAAACAGGTACTTGGAACAGCATTAATCGTACTTCTAAAAATACCTCAATCGTTAGCAATCCTTTTATCACTATAAGCCTTAAGCATGACAACAAAGGTGATAGCTATGGTTACCTGATGGTTCCAAACATTGATCGCACTAGTTTTGATAAATTAGCCAACAGCAAAGAAGTAGAATTACTAGAAAATAGTTCAAAACAACAAGTTATCTATGATAAAAACAGTCAAACTTGGGCTGTTATCAAACACGATAATCAAGAGAGTCTCATTAACAATCAATTCAAAATGAATAAAGCGGGACTTTACCTAGTACAAAAAGTTGGTAATGACTATCAAAATGTCTATTACCAACCTCAAACCATGACAAAAACAGACCAATTAGCTATCTAA
|
| Protein sequence |
+ ...
MKQVVDNQTQNKELVKNGDFNQTNPVSGSWSHTSAREWSAWIDKENTADKSPIIQRTEQGQVSLSSDKGFRGAVTQKVNIDPTKKYEVKFDIETSNKAGQAFLRIMEKKDNNTRLWLSEMTSGTTNKHTLTKIYNPKLNVSEVTLELYYEKGTGSATFDNISMKAKGPKDSEHPQPVTTQIEESVNTALNKNYVFNKADYQYTLTNPSLGKIVGGILYPNATGSTTVKISDKSGKIIKEVPLSVTASTEDKFTKLLDKWNDVTIGNHVYDTNDSNMQKINQKLDETNAKNIKTIKLDSNHTFLWKDLDNLNNSAQLTATYRRLEDLAKQITNPHSTIYKNEKAIRTVKESLAWLHQNFYNVNKDIEGSANWWDFEIGVPRSITATLALMNNYFTDAEIKTYTDPIEHFVPDAGYFRKTLDNPFKALGGNLVDMGRVKIIEGLLRKDNTIIEKTSHSLKNLFTTATKAEGFYADGSYIDHTNVAYTGAYGNVLIDGLTQLLPIIQETDYKISNQELDMVYKWINQSFLPLIVKGELMDMSRGRSISREAASSHAAAVEVLRGFLRLANMSNEERNLDLKSTIKTIITSNKFYNVFNNLKSYSDIANMNKMLNDSTVATKPLKSNLSTFNSMDRLAYYNAEKDFGFALSLHSKRTLNYEGMNDENTRDWYTGDGMFYLYNSDQSHYSNHFWPTVNPYKMAGTTEKDAKREDTTKEFMSKHSKDAKEKTGQVTGTSDFVGSVKLNDHFALAAMDFTNWDRTLTAQKGWVILNDKIVFLGSNIKNTNGIGNVSTTIDQRKDDSKTPYTTYVNGKTIDLKQASSQQFTDTKSVFLESKEPGRNIGYIFFKNSTIDIERKEQTGTWNSINRTSKNTSIVSNPFITISQKHDNKGDSYGYMMVPNIDRTSFDKLANSKEVELLENSSKQQVIYDKNSQTWAVIKHDNQESLINNQFKMNKAGLYLVQKVGNDYQNVYYQPQTMTKTDQLAI
|
| GO Classification |
| component |
| extracellular region |
| function |
| catalytic activity |
| lyase activity |
| carbon-oxygen lyase activity |
| carbon-oxygen lyase activity, acting on polysaccharides |
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