DT-Web

DB08558 - 2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL


Identification
Name 2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL
Accession Number DB08558
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 308.434
Groups experimental
Monoisotopic Weight 308.165744696
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Name Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Gene Name lpxA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6153
Antigen 85-C
Name Antigen 85-C
Gene Name fbpC
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0316
Beta-1 adrenergic receptor
Name Beta-1 adrenergic receptor
Gene Name ADRB1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6453
Lactase-phlorizin hydrolase
Name Lactase-phlorizin hydrolase
Gene Name LCT
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2483

Predictions


Id Partner name Gene Name Score
766 Beta-2 adrenergic receptor ADRB2 0.2313
3923 Cholinesterase BCHE 0.1537
4295 Hypothetical protein VC0232 VC_0232 0.0816
4037 Hypothetical protein GPX1 0.0816
4297 Hypothetical protein SP_1951 0.0816
4521 Hypothetical protein BC_2969 0.0816
4540 Hypothetical protein TM_1070 0.0816
4555 Hypothetical protein MT1739 0.0816
4569 Hypothetical protein mshD 0.0816
4578 Hypothetical protein PA3270 0.0816
4747 Hypothetical protein PA3967 0.0816
5177 Hypothetical protein TM_0096 0.0816
5194 Hypothetical protein PA1204 0.0816
5240 Hypothetical protein Rv2991 0.0816
5370 Hypothetical protein TM_1158 0.0816
5710 Hypothetical protein Tb927.5.1360 0.0816
3028 dTDP-4-dehydrorhamnose 3,5-epimerase rfbC 0.0816
4294 DTDP-4-dehydrorhamnose 3,5-epimerase rmlC 0.0816
5127 DTDP-4-dehydrorhamnose 3,5-epimerase rmlC 0.0816
4296 Phosphonoacetate hydrolase phnA 0.0815
2359 Triggering receptor expressed on myeloid cells 1 TREM1 0.0815
4288 Probable ATP-dependent RNA helicase DDX6 DDX6 0.0815
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0815
3726 D-3-phosphoglycerate dehydrogenase serA 0.0815
4291 D-3-phosphoglycerate dehydrogenase serA 0.0815
2336 2,3-diketo-L-gulonate reductase dlgD 0.071
4290 Hypoxia-inducible factor 1 alpha inhibitor HIF1AN 0.071
4289 Cytochrome P450 TT_P0059 0.071
6262 Cytochrome P450 staP 0.071
2291 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 B3GAT1 0.071
1517 Beta-3 adrenergic receptor ADRB3 0.07
6614 Lactase-like protein LCTL 0.0629
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0567
4119 Cytochrome P450 2D6 CYP2D6 0.0536
3289 Beta-glucosidase A bglA 0.0523
3298 Beta-glucosidase A bglA 0.0523
3747 Cellulase B precursor celB 0.0522
1152 Glycogen phosphorylase, muscle form PYGM 0.0393
1588 Multidrug resistance protein 1 ABCB1 0.029
556 Alpha-1A adrenergic receptor ADRA1A 0.0283
320 5-hydroxytryptamine 1A receptor HTR1A 0.0264
4200 Cytochrome P450 1A2 CYP1A2 0.0179
318 Alpha-2A adrenergic receptor ADRA2A 0.0165
5245 Endo-beta-1,4-xylanase Not Available 0.0162
5246 Xylanase Y BH2105 0.0162
6144 Solute carrier family 22 member 2 SLC22A2 0.0157
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0153
4512 Cytochrome P450 3A4 CYP3A4 0.0152
885 5-hydroxytryptamine 1B receptor HTR1B 0.0147
5247 Endo-1,4-beta-xylanase Not Available 0.0141
5248 Endo-1,4-beta-xylanase xlnA 0.0141
5250 Endo-1,4-beta-xylanase xyl 0.0141
4669 Endo-1,4-beta-xylanase A xynA 0.0141
4715 Endo-1,4-beta-xylanase A xlnA 0.0141
5560 Endo-1,4-beta-xylanase A xynA 0.0141
5023 Glycoside hydrolase Not Available 0.0141
5024 Glycoside hydrolase Not Available 0.0141
4808 Endoxylanase xynC 0.0141
4819 Hydrolase Not Available 0.013
5249 Hydrolase Not Available 0.013
5436 Hydrolase Not Available 0.013
2430 Chondroitinase B cslB 0.013
2581 Chondroitinase AC cslA 0.0127
3365 Beta-amylase spoII 0.0123
4830 Aldose 1-epimerase galM 0.0123
632 Alpha-1B adrenergic receptor ADRA1B 0.012
3810 Catechol O-methyltransferase COMT 0.0109
629 Alpha-2B adrenergic receptor ADRA2B 0.0106
6024 Cytochrome P450 1A1 CYP1A1 0.0103
3941 Amine oxidase [flavin-containing] A MAOA 0.0102
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0096
6016 Cytochrome P450 2C19 CYP2C19 0.0096
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0093
378 Alpha-2C adrenergic receptor ADRA2C 0.0088
1820 Beta-nerve growth factor NGF 0.0085
6145 Solute carrier family 22 member 1 SLC22A1 0.0085
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.008
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0077
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0077
828 Phenylalanine-4-hydroxylase PAH 0.0077
3109 Phenylalanine-4-hydroxylase phhA 0.0077
3962 Egl nine homolog 3 EGLN3 0.0077
3948 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 ALKBH2 0.0077
3956 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ALKBH3 0.0077
3946 Hypothetical protein DKFZp686H15154 OGFOD2 0.0077
189 Solute carrier family 23 member 1 SLC23A1 0.0077
3966 Putative HIF-prolyl hydroxylase PH-4 P4HTM 0.0077
3954 Egl nine homolog 2 EGLN2 0.0077
3953 2-oxoglutarate and iron-dependent oxygenase domain containing 1 OGFOD1 0.0077
3935 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 PLOD2 0.0077
3958 Jumonji/ARID domain-containing protein 1D KDM5D 0.0077
3943 Peptidyl-glycine alpha-amidating monooxygenase PAM 0.0076
3960 Egl nine homolog 1 EGLN1 0.0076
789 Alpha-1D adrenergic receptor ADRA1D 0.0074
2485 Hyaluronate lyase SP_0314 0.0068
3172 Hyaluronate lyase hylB 0.0068
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0065
2245 Xylose isomerase xylA 0.0065
2253 Xylose isomerase xylA 0.0065
2260 Xylose isomerase xylA 0.0065
2431 Xylose isomerase xylA 0.0065
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0063
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0063
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0063
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0063
824 Sodium-dependent serotonin transporter SLC6A4 0.0061
777 Tumor necrosis factor TNF 0.0058
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0057
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0057
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0057
713 Sodium-dependent dopamine transporter SLC6A3 0.0055
153 Dopamine beta-hydroxylase DBH 0.0054
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0054
23 D(1A) dopamine receptor DRD1 0.0054
2300 Lysozyme E 0.0052
3633 Lysozyme R 0.0052
5597 Lysozyme 17 0.0052
1176 Mitogen-activated protein kinase 1 MAPK1 0.0043
4878 Glycoprotein hormones alpha chain CGA 0.0041
1072 Granzyme B GZMB 0.0041
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0041
4877 Beta-mannanase man 0.0041
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0041
4889 Ig epsilon chain C region IGHE 0.0041
4850 Beta-2-glycoprotein 1 APOH 0.0041
4880 Membrane cofactor protein CD46 0.0041
1354 Beta-glucuronidase GUSB 0.0041
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0041
4856 CD209 antigen CD209 0.0041
757 Fusion glycoprotein F0 F 0.0041
4875 Fusion glycoprotein F0 F 0.0041
4189 Alpha-galactosidase A GLA 0.0041
4869 Major capsid protein A430L 0.0041
4852 Reticulon-4 receptor RTN4R 0.0041
442 Envelope glycoprotein gp41 0.0041
4859 Envelope glycoprotein env 0.0041
4845 ADAM 33 ADAM33 0.0041
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0041
4721 Beta-1,4-mannanase manA 0.0041
3352 Structural polyprotein Not Available 0.0041
3628 Structural polyprotein Not Available 0.0041
4892 Structural polyprotein Not Available 0.0041
118 Organic cation/carnitine transporter 2 SLC22A5 0.004
4861 Interleukin-6 receptor alpha chain IL6R 0.0036
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0036
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0036
793 T-cell surface antigen CD2 CD2 0.0036
3837 Cytokine receptor common beta chain CSF2RB 0.0036
4757 Cytochrome P450 2C9 CYP2C9 0.0036
1184 Interferon beta IFNB1 0.0035
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0035
6858 Inactive carboxylesterase 4 CES1P1 0.0035
1379 Interleukin-12 subunit beta IL12B 0.0035
4890 Hemagglutinin HA 0.0035
6566 Hemagglutinin Not Available 0.0035
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0032
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0032
2297 Genome polyprotein Not Available 0.0032
2322 Genome polyprotein Not Available 0.0032
2694 Genome polyprotein Not Available 0.0032
2719 Genome polyprotein Not Available 0.0032
2860 Genome polyprotein Not Available 0.0032
2928 Genome polyprotein Not Available 0.0032
3160 Genome polyprotein Not Available 0.0032
3260 Genome polyprotein Not Available 0.0032
4783 Genome polyprotein Not Available 0.0032
5726 Genome polyprotein Not Available 0.0032
5779 Genome polyprotein Not Available 0.0032
5867 Genome polyprotein Not Available 0.0032
6253 Genome polyprotein Not Available 0.0032
6301 Genome polyprotein Not Available 0.0032
6380 Genome polyprotein Not Available 0.0032
6381 Genome polyprotein Not Available 0.0032
6437 Genome polyprotein Not Available 0.0032
6520 Genome polyprotein Not Available 0.0032
6521 Genome polyprotein Not Available 0.0032
6652 Genome polyprotein Not Available 0.0032
6734 Genome polyprotein Not Available 0.0032
6735 Genome polyprotein Not Available 0.0032
6736 Genome polyprotein Not Available 0.0032
6737 Genome polyprotein Not Available 0.0032
6738 Genome polyprotein Not Available 0.0032
6739 Genome polyprotein Not Available 0.0032
6744 Genome polyprotein Not Available 0.0032
6748 Genome polyprotein Not Available 0.0032
6894 Genome polyprotein Not Available 0.0032
6898 Genome polyprotein Not Available 0.0032
3140 Hemagglutinin-neuraminidase HN 0.0032
3609 Hemagglutinin-neuraminidase HN 0.0032
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0032
3444 Cyanovirin-N Not Available 0.0032
1859 Prostatic acid phosphatase ACPP 0.0032
1374 Natriuretic peptides B NPPB 0.0032
1827 Gap junction alpha-1 protein GJA1 0.0032
1908 Vascular cell adhesion protein 1 VCAM1 0.0032
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0031
4787 Envelope glycoprotein gp160 env 0.003
4820 Envelope glycoprotein gp160 env 0.003
5727 Envelope glycoprotein gp160 env 0.003
4666 Fucose-binding lectin PA-IIL lecB 0.003
2372 Bifunctional tail protein 9 0.003
131 Synaptic vesicular amine transporter SLC18A2 0.003
852 Heparin cofactor 2 SERPIND1 0.0029
554 Low-density lipoprotein receptor LDLR 0.0029
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0029
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0029
6107 Cytochrome P450 3A7 CYP3A7 0.0029
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0028
3480 Mannan endo-1,4-beta-mannosidase manA 0.0028
64 Neuraminidase NA 0.0028
641 Neuraminidase NA 0.0028
2676 Neuraminidase NA 0.0028
3026 Neuraminidase NA 0.0028
3519 Neuraminidase NA 0.0028
6007 Neuraminidase NA 0.0028
4118 Cytochrome P450 3A5 CYP3A5 0.0027
595 Fibrinogen alpha chain FGA 0.0027
1439 Lactotransferrin LTF 0.0027
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0027
1243 Cathepsin D CTSD 0.0026
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0026
6147 Solute carrier family 22 member 3 SLC22A3 0.0026
958 Insulin-like growth factor 1 receptor IGF1R 0.0026
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0026
6307 Ig gamma-2 chain C region IGHG2 0.0025
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0025
20 Prostaglandin G/H synthase 1 PTGS1 0.0024
6500 Phospholipase A2 PLA2G1B 0.0024
3939 Amine oxidase [flavin-containing] B MAOB 0.0023
183 Vascular endothelial growth factor A VEGFA 0.0023
233 Potassium channel subfamily K member 2 KCNK2 0.0023
3814 Complement C1r subcomponent C1R 0.0023
2207 Rhodopsin RHO 0.0022
309 Antithrombin-III SERPINC1 0.0022
6151 Monocarboxylate transporter 10 SLC16A10 0.0021
4785 Ig gamma-1 chain C region IGHG1 0.002
76 Nitric-oxide synthase, brain NOS1 0.002
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0019
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0019
1360 Sphingomyelin phosphodiesterase SMPD1 0.0019
6013 Cytochrome P450 2E1 CYP2E1 0.0019
502 5-hydroxytryptamine 2A receptor HTR2A 0.0019
492 Histamine H1 receptor HRH1 0.0018
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0018
952 Dipeptidyl peptidase 4 DPP4 0.0018
4604 Liver carboxylesterase 1 CES1 0.0017
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0017
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0017
3947 Xanthine dehydrogenase/oxidase XDH 0.0016
1256 5-hydroxytryptamine 6 receptor HTR6 0.0016
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0015
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0015
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0015
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0015
124 Histamine H2 receptor HRH2 0.0014
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0014
716 5-hydroxytryptamine 7 receptor HTR7 0.0014
6432 Transporter snf 0.0014
4924 Cytochrome P450 2C8 CYP2C8 0.0014
436 5-hydroxytryptamine 2B receptor HTR2B 0.0013
432 D(4) dopamine receptor DRD4 0.0013
638 D(3) dopamine receptor DRD3 0.0012
590 5-hydroxytryptamine 2C receptor HTR2C 0.0012
831 D(2) dopamine receptor DRD2 0.001
6106 Cytochrome P450 2C18 CYP2C18 0.001
274 Muscarinic acetylcholine receptor M5 CHRM5 0.001
833 Organic cation/carnitine transporter 1 SLC22A4 0.001
587 Serum albumin ALB 0.0009
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0009
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0008
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0008
5718 Cytochrome P450 2A6 CYP2A6 0.0008
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0008
6030 Cytochrome P450 2B6 CYP2B6 0.0007
↑