DT-Web

DB04273 - 8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine


Identification
Name 8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine
Accession Number DB04273 (EXPT02072)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 216.107
Groups experimental
Monoisotopic Weight 215.026854771
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Phenylethanolamine N-methyltransferase
Name Phenylethanolamine N-methyltransferase
Gene Name PNMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8616

Predictions


Id Partner name Gene Name Score
4309 S-adenosyl-L-methionine-dependent methyltransferase mraW rsmH 0.0065
3724 Protein methyltransferase hemK hemK 0.0064
4329 Uroporphyrinogen-III C-methyltransferase cobA 0.0064
4313 Probable tRNA/rRNA methyltransferase HI0766 trmL 0.0064
4316 Mycolic acid synthase pcaA 0.0064
4331 Chemotaxis protein methyltransferase cheR 0.0064
4333 Protein-L-isoaspartate O-methyltransferase pcm 0.0064
2551 Cobalt-precorrin-4 C(11)-methyltransferase cbiF 0.0064
4324 Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 SETD7 0.0064
1998 Protein-L-isoaspartate(D-aspartate) O-methyltransferase PCMT1 0.0064
4330 Hypothetical protein TTHA0667 TTHA0667 0.0064
4315 DNA adenine methylase DAM 0.0064
4323 Modification methylase HhaI hhaIM 0.0064
4314 Modification methylase PvuII pvuIIM 0.0064
4310 rRNA adenine N-6-methyltransferase ermC' 0.0056
4302 METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2 mmaA2 0.0056
2242 Cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2 0.0056
3117 Carminomycin 4-O-methyltransferase dnrK 0.0056
4306 HemK protein TM_0488 0.0056
4332 Modification methylase TaqI taqIM 0.0056
2297 Genome polyprotein Not Available 0.0056
2322 Genome polyprotein Not Available 0.0056
2694 Genome polyprotein Not Available 0.0056
2719 Genome polyprotein Not Available 0.0056
2860 Genome polyprotein Not Available 0.0056
2928 Genome polyprotein Not Available 0.0056
3160 Genome polyprotein Not Available 0.0056
3260 Genome polyprotein Not Available 0.0056
4783 Genome polyprotein Not Available 0.0056
5726 Genome polyprotein Not Available 0.0056
5779 Genome polyprotein Not Available 0.0056
5867 Genome polyprotein Not Available 0.0056
6253 Genome polyprotein Not Available 0.0056
6301 Genome polyprotein Not Available 0.0056
6380 Genome polyprotein Not Available 0.0056
6381 Genome polyprotein Not Available 0.0056
6437 Genome polyprotein Not Available 0.0056
6520 Genome polyprotein Not Available 0.0056
6521 Genome polyprotein Not Available 0.0056
6652 Genome polyprotein Not Available 0.0056
6734 Genome polyprotein Not Available 0.0056
6735 Genome polyprotein Not Available 0.0056
6736 Genome polyprotein Not Available 0.0056
6737 Genome polyprotein Not Available 0.0056
6738 Genome polyprotein Not Available 0.0056
6739 Genome polyprotein Not Available 0.0056
6744 Genome polyprotein Not Available 0.0056
6748 Genome polyprotein Not Available 0.0056
6894 Genome polyprotein Not Available 0.0056
6898 Genome polyprotein Not Available 0.0056
4318 Siroheme synthase cysG 0.0052
4327 RdmB rdmB 0.0052
2653 Modification methylase RsrI rsrIM 0.0052
4311 tRNA TRDMT1 0.0046
4325 tRNA trmD 0.0046
4328 tRNA trmD 0.0046
2557 Cap-specific mRNA PAPS 0.0043
411 Glycine N-methyltransferase GNMT 0.0039
624 Guanidinoacetate N-methyltransferase GAMT 0.0039
4203 Histamine N-methyltransferase HNMT 0.0035
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