Identification | |||||||||||||
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Name | Tazobactam | ||||||||||||
Accession Number | DB01606 (EXPT03012) | ||||||||||||
Type | small molecule | ||||||||||||
Description | Tazobactam is a antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases. | ||||||||||||
Structure |
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Categories (*) | |||||||||||||
Molecular Weight | 300.291 | ||||||||||||
Groups | approved | ||||||||||||
Monoisotopic Weight | 300.052840204 | ||||||||||||
Pharmacology | |||||||||||||
Indication | Used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action. | ||||||||||||
Mechanism of action | Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin. | ||||||||||||
Absorption | Not Available | ||||||||||||
Protein binding | Not Available | ||||||||||||
Biotransformation | Not Available | ||||||||||||
Route of elimination | Not Available | ||||||||||||
Toxicity | Not Available | ||||||||||||
Affected organisms |
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Interactions | |||||||||||||
Drug Interactions |
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Food Interactions | Not Available |
Beta-lactamase SHV-1 precursor | |
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Name | Beta-lactamase SHV-1 precursor |
Gene Name | bla |
Pharmacological action | unknown |
Actions | inhibitor |
References | |
DTHybrid score | 1.5162 |
Beta-lactamase TEM | |
Name | Beta-lactamase TEM |
Gene Name | bla |
Pharmacological action | yes |
Actions | inhibitor |
References |
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DTHybrid score | 1.0798 |
Id | Partner name | Gene Name | Score |
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6396 | Beta-lactamase TEM | bla | 1.0798 |
3701 | Beta-lactamase SHV-2 precursor | bla | 0.2002 |
6691 | Beta-lactamase SHV-1 | bla | 0.0876 |
6897 | Class C beta-lactamase | Not Available | 0.0848 |
4629 | Beta-lactamase CTX-M-9a | blaCTX-M-9a | 0.0719 |
332 | Beta-lactamase | blaZ | 0.0707 |
2478 | Beta-lactamase | ampC | 0.0707 |
2613 | Beta-lactamase | ampC | 0.0707 |
2635 | Beta-lactamase | ampC | 0.0707 |
2700 | Beta-lactamase | penP | 0.0707 |
5445 | Beta-lactamase | blaB | 0.0707 |
6019 | Beta-lactamase | SHV-7 | 0.0707 |
6701 | Beta-lactamase | cphA | 0.0707 |