DT-Web

DB08765 - 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE


Identification
Name 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE
Accession Number DB08765
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 230.264
Groups experimental
Monoisotopic Weight 229.981983448
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Carbonic anhydrase 2
Name Carbonic anhydrase 2
Gene Name CA2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4206
Macrophage migration inhibitory factor
Name Macrophage migration inhibitory factor
Gene Name MIF
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3871

Predictions


Id Partner name Gene Name Score
2369 Photoactive yellow protein pyp 0.0854
96 Histidine ammonia-lyase HAL 0.0853
6257 Histidine ammonia-lyase Not Available 0.0853
6536 Histidine ammonia-lyase hutH 0.0853
6564 Prephenate dehydrogenase tyrA 0.0853
295 Carbonic anhydrase 1 CA1 0.0835
592 Carbonic anhydrase 4 CA4 0.0461
54 Prothrombin F2 0.0386
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0209
3623 Divalent-cation tolerance protein cutA cutA 0.0206
466 Solute carrier family 12 member 3 SLC12A3 0.0202
558 Solute carrier family 12 member 1 SLC12A1 0.0157
6126 Carbonic anhydrase 7 CA7 0.0154
3226 UPF0234 protein HI1034 HI_1034 0.0135
1729 Solute carrier family 22 member 6 SLC22A6 0.0125
3007 Carbonic anhydrase 12 CA12 0.0117
4205 Carbonic anhydrase 9 CA9 0.0117
3105 M-phase inducer phosphatase 2 CDC25B 0.0108
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0105
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0073
3627 UPF0190 protein yedY yedY 0.0067
4512 Cytochrome P450 3A4 CYP3A4 0.0067
1392 Catenin beta-1 CTNNB1 0.0067
3352 Structural polyprotein Not Available 0.0067
3628 Structural polyprotein Not Available 0.0067
4892 Structural polyprotein Not Available 0.0067
1405 Thiopurine S-methyltransferase TPMT 0.0066
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0061
6131 Carbonic anhydrase 14 CA14 0.0052
6122 Carbonic anhydrase 3 CA3 0.0051
4757 Cytochrome P450 2C9 CYP2C9 0.0049
4533 Glyoxalase family protein BC_1747 0.0047
310 Solute carrier family 12 member 2 SLC12A2 0.0046
5591 Complement component C8 gamma chain C8G 0.0046
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0046
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0046
4695 UPF0124 protein yfiH yfiH 0.0046
365 Dihydrofolate reductase DHFR 0.0046
2381 Dihydrofolate reductase DFR1 0.0046
2833 Dihydrofolate reductase Not Available 0.0046
2931 Dihydrofolate reductase folA 0.0046
3544 Dihydrofolate reductase folA 0.0046
3682 Dihydrofolate reductase folA 0.0046
6642 Dihydrofolate reductase folA 0.0046
6756 Dihydrofolate reductase dfrA 0.0046
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0046
2300 Lysozyme E 0.0046
3633 Lysozyme R 0.0046
5597 Lysozyme 17 0.0046
5575 Short tail fiber protein 12 0.0046
5587 Iron(III)-binding periplasmic protein fbpA 0.0046
5600 Pyruvate decarboxylase pdc 0.0046
5582 Regulator of transcription; stringent starvation protein A sspA 0.0046
2838 Ribose-5-phosphate isomerase A rpiA 0.0046
2952 Ribose-5-phosphate isomerase A rpiA 0.0046
5595 Ribose-5-phosphate isomerase A rpiA 0.0046
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0046
5593 Transferase Not Available 0.0046
4238 50S ribosomal protein L4 rplD 0.0046
5578 50S ribosomal protein L4 rplD 0.0046
6173 50S ribosomal protein L4 rplD 0.0046
6219 50S ribosomal protein L4 rplD 0.0046
5060 Intron-associated endonuclease 1 ITEVIR 0.0046
5588 Cell division protein FtsY TM_0570 0.0046
5590 N utilization substance protein B homolog nusB 0.0046
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0046
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0046
4375 Glutamine synthetase 1 glnA1 0.0046
5581 Beta-fructosidase bfrA 0.0046
5580 Hexon protein PII 0.0046
5574 Invasin YPTB1668 0.0046
3583 6-phosphogluconolactonase pgl 0.0044
5006 RNASE4 protein RNASE4 0.004
4992 Cytochrome c peroxidase Not Available 0.004
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.004
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.004
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.004
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.004
3132 Tryptophan synthase alpha chain trpA 0.004
6568 Tryptophan synthase alpha chain trpA 0.004
5328 Prostaglandin F synthase Tb11.02.2310 0.004
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.004
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.004
3729 Citrate synthase gltA 0.004
4575 Citrate synthase cit 0.004
4580 Citrate synthase gltA 0.004
2555 Pol polyprotein pol 0.004
3242 Pol polyprotein gag-pol 0.004
3471 Pol polyprotein gag-pro-pol 0.004
5256 Pol polyprotein pol 0.004
6469 Pol polyprotein gag-pol 0.004
6565 Pol polyprotein Not Available 0.004
315 Arginase-1 ARG1 0.004
2149 Angiogenin ANG 0.0037
2603 Beta-lactamase II blm 0.0037
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0037
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0037
2521 Cell division protein ftsZ ftsZ 0.0037
3301 Cell division protein ftsZ ftsZ 0.0037
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0036
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0035
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0035
2286 Isocitrate dehydrogenase [NADP] icd 0.0035
2302 Isocitrate dehydrogenase [NADP] icd 0.0035
2771 Isocitrate dehydrogenase [NADP] icd 0.0035
3486 Fumarate hydratase class II fumC 0.0035
2942 Sialidase nanH 0.0035
3546 Sialidase nedA 0.0035
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0033
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0033
1123 Eosinophil cationic protein RNASE3 0.0033
332 Beta-lactamase blaZ 0.0032
2478 Beta-lactamase ampC 0.0032
2613 Beta-lactamase ampC 0.0032
2635 Beta-lactamase ampC 0.0032
2700 Beta-lactamase penP 0.0032
5445 Beta-lactamase blaB 0.0032
6019 Beta-lactamase SHV-7 0.0032
6701 Beta-lactamase cphA 0.0032
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0032
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0032
2697 Uridine-cytidine kinase 2 UCK2 0.0032
1025 Aquaporin-1 AQP1 0.0032
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0032
857 Malate dehydrogenase, mitochondrial MDH2 0.0032
2452 Tryptophanyl-tRNA synthetase trpS 0.0032
5579 Carboxypeptidase B CPB1 0.003
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0029
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0029
3426 Glutamine synthetase glnA 0.0028
3987 Glutamine synthetase GLUL 0.0028
411 Glycine N-methyltransferase GNMT 0.0028
6016 Cytochrome P450 2C19 CYP2C19 0.0028
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0028
5682 Ribonuclease pancreatic RNASE1 0.0027
128 Adenine phosphoribosyltransferase APRT 0.0025
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0025
822 Aldose reductase AKR1B1 0.0023
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0023
1024 Solute carrier family 22 member 11 SLC22A11 0.0022
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0021
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.002
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.002
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0017
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0017
6013 Cytochrome P450 2E1 CYP2E1 0.0017
997 Protein kinase C beta type PRKCB 0.0015
2408 Tyrosine-protein kinase SYK SYK 0.0014
118 Organic cation/carnitine transporter 2 SLC22A5 0.0013
1970 Protein kinase C alpha type PRKCA 0.0013
6142 Solute carrier family 22 member 8 SLC22A8 0.0013
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0012
634 Squalene monooxygenase SQLE 0.0012
7196 Squalene monooxygenase ERG1 0.0012
587 Serum albumin ALB 0.0012
2236 Casein kinase II subunit alpha CSNK2A1 0.0011
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.001
4119 Cytochrome P450 2D6 CYP2D6 0.001
6130 Carbonic anhydrase 13 CA13 0.0009
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0009
6127 Carbonic anhydrase-related protein CA8 0.0009
6129 Carbonic anhydrase-related protein 11 CA11 0.0009
6128 Carbonic anhydrase-related protein 10 CA10 0.0009
6135 Sodium channel subunit beta-4 SCN4B 0.0009
6133 Sodium channel subunit beta-2 SCN2B 0.0009
6134 Sodium channel subunit beta-3 SCN3B 0.0009
6132 Sodium channel subunit beta-1 SCN1B 0.0009
4037 Hypothetical protein GPX1 0.0008
4297 Hypothetical protein SP_1951 0.0008
4521 Hypothetical protein BC_2969 0.0008
4540 Hypothetical protein TM_1070 0.0008
4555 Hypothetical protein MT1739 0.0008
4569 Hypothetical protein mshD 0.0008
4578 Hypothetical protein PA3270 0.0008
4747 Hypothetical protein PA3967 0.0008
5177 Hypothetical protein TM_0096 0.0008
5194 Hypothetical protein PA1204 0.0008
5240 Hypothetical protein Rv2991 0.0008
5370 Hypothetical protein TM_1158 0.0008
5710 Hypothetical protein Tb927.5.1360 0.0008
4527 Putative hydrolase ycdX ycdX 0.0008
4536 Transcriptional regulator, IclR family TM_0065 0.0008
2501 Protein ygbM ygbM 0.0008
4545 Molybdopterin-converting factor subunit 2 moaE 0.0008
4522 Arginine N-succinyltransferase subunit alpha astA 0.0008
4106 Guanylate kinase GUK1 0.0008
4516 Guanylate kinase gmk 0.0008
4538 Hypothetical protein VC1899 VC_1899 0.0008
4529 Oxalate decarboxylase oxdC oxdC 0.0008
4514 Citrate lyase beta subunit-like protein citE 0.0008
4781 Citrate lyase beta subunit-like protein DR_1240 0.0008
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0008
4524 Mannose-6-phosphate isomerase yvyI 0.0008
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0008
4547 Iron binding protein FbpA fbpA 0.0008
4548 Gyrase B gyrB 0.0008
4546 Aminotransferase, putative TM_1131 0.0008
658 Para-aminobenzoate synthase component 1 pabB 0.0008
4515 Peripheral plasma membrane protein CASK CASK 0.0008
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0008
4496 C-terminal-binding protein 1 CTBP1 0.0008
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0007
4517 Probable butyrate kinase 2 buk2 0.0007
3261 Signal recognition particle protein ffh 0.0007
4528 Phenazine biosynthesis protein PhzD phzD1 0.0007
56 Delta-aminolevulinic acid dehydratase ALAD 0.0007
2356 Delta-aminolevulinic acid dehydratase hemB 0.0007
3613 Delta-aminolevulinic acid dehydratase hemB 0.0007
3674 Delta-aminolevulinic acid dehydratase hemB 0.0007
3759 Glutathione S-transferase gst 0.0007
4541 Glutathione S-transferase GST 0.0007
4542 Glutaminase 1 glsA1 0.0007
4544 Glutaminase 1 glsA1 0.0007
2929 (S)-2-haloacid dehalogenase dhlB 0.0007
2995 (S)-2-haloacid dehalogenase Not Available 0.0007
3237 Beta-lactamase OXA-2 bla 0.0007
4532 Gephyrin GPHN 0.0007
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0007
2230 Catalase CAT 0.0007
3249 Catalase katA 0.0007
3625 Catalase katA 0.0007
4539 Catalase katA 0.0007
4941 Catalase katB 0.0007
4531 Putative ketoacyl reductase actIII 0.0007
2775 Dihydroorotate dehydrogenase pyrD 0.0007
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0007
3467 Methylglyoxal synthase mgsA 0.0007
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0006
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0006
2688 Peptide deformylase def 0.0006
2708 Peptide deformylase def 0.0006
3004 Peptide deformylase def 0.0006
4337 Peptide deformylase def 0.0006
4338 Peptide deformylase def 0.0006
5368 Peptide deformylase def 0.0006
5371 Peptide deformylase def 0.0006
6375 Peptide deformylase def 0.0006
6378 Peptide deformylase def 0.0006
6379 Peptide deformylase def 0.0006
6776 Peptide deformylase def 0.0006
6900 Peptide deformylase def 0.0006
4534 Cytohesin-2 CYTH2 0.0006
6024 Cytochrome P450 1A1 CYP1A1 0.0006
2548 Subtilisin Carlsberg apr 0.0006
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0006
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0006
6020 Aldehyde oxidase AOX1 0.0005
3939 Amine oxidase [flavin-containing] B MAOB 0.0005
760 Fibroblast growth factor 1 FGF1 0.0005
810 Heme oxygenase 1 HMOX1 0.0005
3391 Heme oxygenase 1 pbsA1 0.0005
3027 Streptavidin Not Available 0.0005
3941 Amine oxidase [flavin-containing] A MAOA 0.0005
500 Monocarboxylate transporter 4 SLC16A3 0.0005
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0004
76 Nitric-oxide synthase, brain NOS1 0.0004
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