DT-Web

DB08180 - 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE


Identification
Name 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE
Accession Number DB08180
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 453.4471
Groups experimental
Monoisotopic Weight 453.204525567
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Name Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Gene Name FNTA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1568
Geranylgeranyl transferase type-1 subunit beta
Name Geranylgeranyl transferase type-1 subunit beta
Gene Name PGGT1B
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8468

Predictions


Id Partner name Gene Name Score
4128 Protein farnesyltransferase subunit beta FNTB 0.7668
6576 Geranylgeranyl transferase type-2 subunit beta RABGGTB 0.142
6575 Geranylgeranyl transferase type-2 subunit alpha RABGGTA 0.1419
6574 GTPase KRas KRAS 0.1075
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.094
853 Farnesyl pyrophosphate synthetase FDPS 0.0816
6571 Guanine nucleotide-binding protein G(T) subunit gamma-T1 GNGT1 0.0279
6573 Phosducin PDC 0.0278
6572 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 0.0278
6577 Rab proteins geranylgeranyltransferase component A 1 CHM 0.0278
6595 Lantibiotic nisin-Z nisZ 0.0228
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0228
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.0198
5744 Undecaprenyl pyrophosphate synthetase uppS 0.0154
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