DT-Web

DB07771 - [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID


Identification
Name [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
Accession Number DB07771
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 359.3976
Groups experimental
Monoisotopic Weight 359.186159587
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


GTPase KRas
Name GTPase KRas
Gene Name KRAS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5805
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Name Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Gene Name FNTA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5505
Protein farnesyltransferase subunit beta
Name Protein farnesyltransferase subunit beta
Gene Name FNTB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4954

Predictions


Id Partner name Gene Name Score
1994 Geranylgeranyl transferase type-1 subunit beta PGGT1B 0.2993
6576 Geranylgeranyl transferase type-2 subunit beta RABGGTB 0.2443
6575 Geranylgeranyl transferase type-2 subunit alpha RABGGTA 0.2442
6571 Guanine nucleotide-binding protein G(T) subunit gamma-T1 GNGT1 0.1367
6573 Phosducin PDC 0.1364
6572 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 0.1364
6577 Rab proteins geranylgeranyltransferase component A 1 CHM 0.1364
6595 Lantibiotic nisin-Z nisZ 0.112
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.1117
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.1096
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.0972
853 Farnesyl pyrophosphate synthetase FDPS 0.0951
5744 Undecaprenyl pyrophosphate synthetase uppS 0.0756
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