DT-Web

DB07437 - 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE


Identification
Name 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE
Accession Number DB07437
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 276.2878
Groups experimental
Monoisotopic Weight 276.11100701
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Uridine phosphorylase
Name Uridine phosphorylase
Gene Name udp
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6806
Uridine phosphorylase 1
Name Uridine phosphorylase 1
Gene Name UPP1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5999

Predictions


Id Partner name Gene Name Score
5132 Uridine phosphorylase udp 1.6806
277 Purine nucleoside phosphorylase PNP 0.0765
2870 Purine nucleoside phosphorylase punA 0.0765
2945 Purine nucleoside phosphorylase punA 0.0765
4659 Purine nucleoside phosphorylase TM_1596 0.0765
4825 Purine nucleoside phosphorylase TTHA1435 0.0765
4226 Uridine phosphorylase 2 UPP2 0.0489
413 Amidophosphoribosyltransferase PPAT 0.0346
2515 Amidophosphoribosyltransferase purF 0.0346
3714 Amidophosphoribosyltransferase purF 0.0346
3755 Nucleoside-specific channel-forming protein tsx precursor tsx 0.0318
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0301
3639 Thymidine phosphorylase deoA 0.0297
3936 Thymidine phosphorylase TYMP 0.0297
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0236
2251 Thymidylate kinase tmk 0.0236
2254 Thymidylate kinase DTYMK 0.0236
3522 Thymidylate kinase tmk 0.0236
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0235
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0235
3917 Methylenetetrahydrofolate reductase MTHFR 0.0231
24 Thymidylate synthase TMP1 0.0228
359 Thymidylate synthase TYMS 0.0228
2626 Thymidylate synthase thyA 0.0228
2729 Thymidylate synthase thyA 0.0228
5352 Thymidylate synthase THYA 0.0228
6136 Multidrug resistance-associated protein 5 ABCC5 0.0208
509 Thymidine kinase TK 0.0198
570 Thymidine kinase TK 0.0198
2559 Thymidine kinase TK 0.0198
3430 Thymidine kinase tdk 0.0198
3518 Thymidine kinase TK 0.0198
5301 Thymidine kinase tdk 0.0198
5771 Thymidine kinase ORF36 0.0198
7009 Thymidine kinase ORF36 0.0198
6171 Solute carrier family 28 member 3 SLC28A3 0.0185
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0185
6143 Solute carrier family 22 member 7 SLC22A7 0.0174
2164 Multidrug resistance-associated protein 4 ABCC4 0.0172
5718 Cytochrome P450 2A6 CYP2A6 0.0154
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0151
587 Serum albumin ALB 0.0139
4924 Cytochrome P450 2C8 CYP2C8 0.0127
4200 Cytochrome P450 1A2 CYP1A2 0.0121
4757 Cytochrome P450 2C9 CYP2C9 0.0117
6145 Solute carrier family 22 member 1 SLC22A1 0.0106
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