DT-Web

DB06953 - 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE


Identification
Name 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE
Accession Number DB06953
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 474.341
Groups experimental
Monoisotopic Weight 473.081015605
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Name Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Gene Name FNTA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3161
Protein farnesyltransferase subunit beta
Name Protein farnesyltransferase subunit beta
Gene Name FNTB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2564

Predictions


Id Partner name Gene Name Score
1994 Geranylgeranyl transferase type-1 subunit beta PGGT1B 0.2993
6574 GTPase KRas KRAS 0.2236
6576 Geranylgeranyl transferase type-2 subunit beta RABGGTB 0.1359
6575 Geranylgeranyl transferase type-2 subunit alpha RABGGTA 0.1359
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.0717
853 Farnesyl pyrophosphate synthetase FDPS 0.0622
6571 Guanine nucleotide-binding protein G(T) subunit gamma-T1 GNGT1 0.0579
6573 Phosducin PDC 0.0578
6572 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 0.0578
6577 Rab proteins geranylgeranyltransferase component A 1 CHM 0.0578
6595 Lantibiotic nisin-Z nisZ 0.0474
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0473
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.0412
5744 Undecaprenyl pyrophosphate synthetase uppS 0.032
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