DT-Web

DB04217 - L-2-amino-3-butynoic acid


Identification
Name L-2-amino-3-butynoic acid
Accession Number DB04217 (EXPT02057)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 99.088
Groups experimental
Monoisotopic Weight 99.032028409
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cystathionine gamma-lyase
Name Cystathionine gamma-lyase
Gene Name CTH
Pharmacological action unknown
Actions Not Available
References
  • Yu S, Sugahara K, Nakayama K, Awata S, Kodama H: Accumulation of cystathionine, cystathionine ketimine, and perhydro-1,4-thiazepine-3,5-dicarboxylic acid in whole brain and various regions of the brain of D, L-propargylglycine-treated rats. Metabolism. 2000 Aug;49(8):1025-9. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0481
Cysteine desulfurase
Name Cysteine desulfurase
Gene Name sufS
Pharmacological action unknown
Actions Not Available
References
  • Mihara H, Fujii T, Kato S, Kurihara T, Hata Y, Esaki N: Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine. J Biochem. 2002 May;131(5):679-85. - Pubmed
DTHybrid score 1.1315

Predictions


Id Partner name Gene Name Score
2638 Formate dehydrogenase H fdhF 0.1872
5294 Nucleoside diphosphate kinase A NME1 0.0995
3204 Thiosulfate sulfurtransferase glpE glpE 0.0625
3527 Thiosulfate sulfurtransferase rhdA 0.0625
4806 Thiosulfate sulfurtransferase TTHA1028 0.0625
6965 Thiosulfate sulfurtransferase TST 0.0625
4801 Diphtheria toxin repressor dtxR 0.0625
4803 3-mercaptopyruvate sulfurtransferase sseA 0.0624
4802 L-cysteine/cystine lyase C-DES c-des 0.0544
3274 Hydroxylamine reductase hcp 0.0544
4804 Hydroxylamine reductase hcp 0.0544
4134 Mercaptopyruvate sulfurtransferase MST 0.0543
89 Cysteine sulfinic acid decarboxylase CSAD 0.0238
171 Cysteine dioxygenase CDO-1 0.0229
774 Cysteinyl-tRNA synthetase, cytoplasmic CARS 0.0228
1314 Thiamine transporter 2 SLC19A3 0.0228
4064 Probable cysteinyl-tRNA synthetase, mitochondrial CARS2 0.0228
169 Cysteine desulfurase, mitochondrial NFS1 0.0219
1999 Methylated-DNA--protein-cysteine methyltransferase MGMT 0.0211
358 Cystathionine beta-synthase CBS 0.0208
586 Aspartate aminotransferase, cytoplasmic GOT1 0.02
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0191
626 Cysteine dioxygenase type 1 CDO1 0.0182
207 Glutathione synthetase GSS 0.0175
5269 Glutathione synthetase gshB 0.0175
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.017
6151 Monocarboxylate transporter 10 SLC16A10 0.0114
3883 Ornithine aminotransferase variant Not Available 0.0047
306 Pyridoxal phosphate phosphatase PDXP 0.0047
3881 Selenocysteine lyase variant Not Available 0.0047
3887 Phosphorylase PYGB 0.0047
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0047
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0047
3911 Uncharacterized protein C20orf38 SPTLC3 0.0047
3906 Serine dehydratase-like SDSL 0.0047
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0047
3891 Putative L-Dopa decarboxylase DDC 0.0047
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.0047
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0047
3886 Migration-inducing protein 4 ALAS1 0.0047
3878 GAD1 protein GAD1 0.0047
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.0047
3893 DDC protein DDC 0.0047
3880 Serine hydroxymethyltransferase 1 Not Available 0.0047
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0047
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0047
664 Glutamate decarboxylase 2 GAD2 0.0047
3890 Glutamate decarboxylase 2 GAD2 0.0047
3894 KIAA0251 protein PDXDC1 0.0047
3875 Glycogen phosphorylase, brain form PYGB 0.0047
3882 Brain glycogen phosphorylase variant Not Available 0.0047
3905 Molybdenum cofactor sulfurase MOCOS 0.0047
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0041
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0041
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0041
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0041
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0041
184 L-serine dehydratase SDS 0.004
491 Serine palmitoyltransferase 1 SPTLC1 0.004
727 Serine palmitoyltransferase 2 SPTLC2 0.004
431 Serine racemase SRR 0.004
435 Kynureninase KYNU 0.004
4654 Kynureninase kynU 0.004
534 Threonine synthase-like 1 THNSL1 0.004
3 Histidine decarboxylase HDC 0.004
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.004
665 Phosphoserine aminotransferase PSAT1 0.004
4652 Phosphoserine aminotransferase serC 0.004
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.004
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.004
420 Glutamate decarboxylase 1 GAD1 0.004
3900 Glutamate decarboxylase 1 GAD1 0.004
499 Arginine decarboxylase ADC 0.0039
472 Ornithine aminotransferase, mitochondrial OAT 0.0039
3913 Glutamic acid decarboxylase GAD65 0.0039
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0038
426 Aspartate aminotransferase, mitochondrial GOT2 0.0037
3877 Growth-inhibiting protein 18 GIG18 0.0036
3884 SHMT2 protein SHMT2 0.0036
3901 SHMT2 protein SHMT2 0.0036
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0036
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0036
3879 Serine hydroxymethyltransferase 2 Not Available 0.0036
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0036
449 Ornithine decarboxylase ODC1 0.0035
349 Serine--pyruvate aminotransferase AGXT 0.0035
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0034
763 Tyrosine aminotransferase TAT 0.0034
5493 Tyrosine aminotransferase Not Available 0.0034
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0034
735 Alanine aminotransferase 1 GPT 0.0034
3904 Alanine aminotransferase 2 GPT2 0.0034
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0034
10 Glycogen phosphorylase, liver form PYGL 0.0032
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0031
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.003
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0029
1152 Glycogen phosphorylase, muscle form PYGM 0.0025
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