DT-Web

DB03991 - 2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid


Identification
Name 2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid
Accession Number DB03991 (EXPT01111)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 291.2546
Groups experimental
Monoisotopic Weight 291.095416525
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Hemagglutinin-neuraminidase
Name Hemagglutinin-neuraminidase
Gene Name HN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7853
Sialidase
Name Sialidase
Gene Name nedA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8787
Neuraminidase
Name Neuraminidase
Gene Name NA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.1599
Hemagglutinin-neuraminidase
Name Hemagglutinin-neuraminidase
Gene Name HN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7853
Trans-sialidase
Name Trans-sialidase
Gene Name TCTS-154
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7231
Sialidase-2
Name Sialidase-2
Gene Name NEU2
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.0635

Predictions


Id Partner name Gene Name Score
2942 Sialidase nanH 0.8787
4335 Trans-sialidase Not Available 0.7231
2570 Tetanus toxin tetX 0.3929
3629 Endo-N-acetylneuraminidase Not Available 0.3221
3547 Enterotoxin type B entB 0.197
4669 Endo-1,4-beta-xylanase A xynA 0.1675
4715 Endo-1,4-beta-xylanase A xlnA 0.1675
5560 Endo-1,4-beta-xylanase A xynA 0.1675
64 Neuraminidase NA 0.1599
641 Neuraminidase NA 0.1599
2676 Neuraminidase NA 0.1599
3519 Neuraminidase NA 0.1599
6007 Neuraminidase NA 0.1599
4819 Hydrolase Not Available 0.1545
5249 Hydrolase Not Available 0.1545
5436 Hydrolase Not Available 0.1545
3382 Glycolipid transfer protein GLTP 0.1345
2592 Beta-galactosidase lacZ 0.119
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0759
4787 Envelope glycoprotein gp160 env 0.0717
4820 Envelope glycoprotein gp160 env 0.0717
5727 Envelope glycoprotein gp160 env 0.0717
1141 Sialidase-1 NEU1 0.0645
3626 Probable polysaccharide deacetylase pdaA pdaA 0.0624
4604 Liver carboxylesterase 1 CES1 0.0603
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0586
4666 Fucose-binding lectin PA-IIL lecB 0.0582
5414 Fiber protein L5 0.053
5418 Fiber protein L5 0.053
1756 E-selectin SELE 0.053
4785 Ig gamma-1 chain C region IGHG1 0.049
1373 Glucosylceramidase GBA 0.0473
1130 Lithostathine 1 alpha REG1A 0.0462
5416 Coat protein VP1 Not Available 0.0461
2324 Botulinum neurotoxin type B botB 0.0425
2058 P-selectin SELP 0.0366
2723 Cholera enterotoxin subunit B ctxB 0.0313
244 Angiotensin-converting enzyme ACE 0.0247
2164 Multidrug resistance-associated protein 4 ABCC4 0.0245
474 Acetylcholinesterase ACHE 0.0242
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0237
3480 Mannan endo-1,4-beta-mannosidase manA 0.0225
6142 Solute carrier family 22 member 8 SLC22A8 0.0222
2207 Rhodopsin RHO 0.0182
4784 Beta-mannosidase manB 0.0179
6695 Beta-mannosidase BT_0458 0.0179
2297 Genome polyprotein Not Available 0.0156
2322 Genome polyprotein Not Available 0.0156
2694 Genome polyprotein Not Available 0.0156
2719 Genome polyprotein Not Available 0.0156
2860 Genome polyprotein Not Available 0.0156
2928 Genome polyprotein Not Available 0.0156
3160 Genome polyprotein Not Available 0.0156
3260 Genome polyprotein Not Available 0.0156
4783 Genome polyprotein Not Available 0.0156
5726 Genome polyprotein Not Available 0.0156
5779 Genome polyprotein Not Available 0.0156
5867 Genome polyprotein Not Available 0.0156
6253 Genome polyprotein Not Available 0.0156
6301 Genome polyprotein Not Available 0.0156
6380 Genome polyprotein Not Available 0.0156
6381 Genome polyprotein Not Available 0.0156
6437 Genome polyprotein Not Available 0.0156
6520 Genome polyprotein Not Available 0.0156
6521 Genome polyprotein Not Available 0.0156
6652 Genome polyprotein Not Available 0.0156
6734 Genome polyprotein Not Available 0.0156
6735 Genome polyprotein Not Available 0.0156
6736 Genome polyprotein Not Available 0.0156
6737 Genome polyprotein Not Available 0.0156
6738 Genome polyprotein Not Available 0.0156
6739 Genome polyprotein Not Available 0.0156
6744 Genome polyprotein Not Available 0.0156
6748 Genome polyprotein Not Available 0.0156
6894 Genome polyprotein Not Available 0.0156
6898 Genome polyprotein Not Available 0.0156
3437 Eosinophil lysophospholipase CLC 0.0144
4878 Glycoprotein hormones alpha chain CGA 0.0143
1072 Granzyme B GZMB 0.0143
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0143
4877 Beta-mannanase man 0.0142
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0142
4189 Alpha-galactosidase A GLA 0.0142
4850 Beta-2-glycoprotein 1 APOH 0.0142
4880 Membrane cofactor protein CD46 0.0142
4889 Ig epsilon chain C region IGHE 0.0142
4856 CD209 antigen CD209 0.0142
442 Envelope glycoprotein gp41 0.0142
4859 Envelope glycoprotein env 0.0142
4852 Reticulon-4 receptor RTN4R 0.0142
4869 Major capsid protein A430L 0.0142
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0142
757 Fusion glycoprotein F0 F 0.0142
4875 Fusion glycoprotein F0 F 0.0142
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0142
1354 Beta-glucuronidase GUSB 0.0142
4721 Beta-1,4-mannanase manA 0.0142
3352 Structural polyprotein Not Available 0.0142
3628 Structural polyprotein Not Available 0.0142
4892 Structural polyprotein Not Available 0.0142
4845 ADAM 33 ADAM33 0.0142
6858 Inactive carboxylesterase 4 CES1P1 0.0124
1184 Interferon beta IFNB1 0.0124
1379 Interleukin-12 subunit beta IL12B 0.0124
793 T-cell surface antigen CD2 CD2 0.0124
4861 Interleukin-6 receptor alpha chain IL6R 0.0124
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0124
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0124
4890 Hemagglutinin HA 0.0124
6566 Hemagglutinin Not Available 0.0124
3837 Cytokine receptor common beta chain CSF2RB 0.0124
3444 Cyanovirin-N Not Available 0.0114
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0114
1859 Prostatic acid phosphatase ACPP 0.0114
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0114
6131 Carbonic anhydrase 14 CA14 0.0114
3923 Cholinesterase BCHE 0.0109
2372 Bifunctional tail protein 9 0.0108
554 Low-density lipoprotein receptor LDLR 0.0106
852 Heparin cofactor 2 SERPIND1 0.0104
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0104
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0103
20 Prostaglandin G/H synthase 1 PTGS1 0.0099
1439 Lactotransferrin LTF 0.0097
595 Fibrinogen alpha chain FGA 0.0095
1243 Cathepsin D CTSD 0.0094
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0093
2430 Chondroitinase B cslB 0.0092
958 Insulin-like growth factor 1 receptor IGF1R 0.0092
6307 Ig gamma-2 chain C region IGHG2 0.009
2581 Chondroitinase AC cslA 0.009
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0088
5591 Complement component C8 gamma chain C8G 0.0088
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0088
5582 Regulator of transcription; stringent starvation protein A sspA 0.0088
5590 N utilization substance protein B homolog nusB 0.0088
4695 UPF0124 protein yfiH yfiH 0.0088
5588 Cell division protein FtsY TM_0570 0.0088
5587 Iron(III)-binding periplasmic protein fbpA 0.0088
2838 Ribose-5-phosphate isomerase A rpiA 0.0088
2952 Ribose-5-phosphate isomerase A rpiA 0.0088
5595 Ribose-5-phosphate isomerase A rpiA 0.0088
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0088
5581 Beta-fructosidase bfrA 0.0088
4238 50S ribosomal protein L4 rplD 0.0088
5578 50S ribosomal protein L4 rplD 0.0088
6173 50S ribosomal protein L4 rplD 0.0088
6219 50S ribosomal protein L4 rplD 0.0088
4375 Glutamine synthetase 1 glnA1 0.0088
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0088
2300 Lysozyme E 0.0088
3633 Lysozyme R 0.0088
5597 Lysozyme 17 0.0088
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0088
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0088
5593 Transferase Not Available 0.0088
5060 Intron-associated endonuclease 1 ITEVIR 0.0088
5574 Invasin YPTB1668 0.0088
5575 Short tail fiber protein 12 0.0088
5600 Pyruvate decarboxylase pdc 0.0088
5580 Hexon protein PII 0.0088
6847 Lactase-phlorizin hydrolase LCT 0.0088
6500 Phospholipase A2 PLA2G1B 0.0087
309 Antithrombin-III SERPINC1 0.008
3814 Complement C1r subcomponent C1R 0.0079
4533 Glyoxalase family protein BC_1747 0.0076
3132 Tryptophan synthase alpha chain trpA 0.0076
6568 Tryptophan synthase alpha chain trpA 0.0076
4992 Cytochrome c peroxidase Not Available 0.0076
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0076
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0076
3729 Citrate synthase gltA 0.0076
4575 Citrate synthase cit 0.0076
4580 Citrate synthase gltA 0.0076
5006 RNASE4 protein RNASE4 0.0076
5328 Prostaglandin F synthase Tb11.02.2310 0.0076
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0076
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0076
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0076
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0076
2555 Pol polyprotein pol 0.0076
3242 Pol polyprotein gag-pol 0.0076
3471 Pol polyprotein gag-pro-pol 0.0076
5256 Pol polyprotein pol 0.0076
6469 Pol polyprotein gag-pol 0.0076
6565 Pol polyprotein Not Available 0.0076
76 Nitric-oxide synthase, brain NOS1 0.0073
2603 Beta-lactamase II blm 0.007
3583 6-phosphogluconolactonase pgl 0.007
2149 Angiogenin ANG 0.007
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.007
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.007
2521 Cell division protein ftsZ ftsZ 0.007
3301 Cell division protein ftsZ ftsZ 0.007
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0067
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0066
2286 Isocitrate dehydrogenase [NADP] icd 0.0066
2302 Isocitrate dehydrogenase [NADP] icd 0.0066
2771 Isocitrate dehydrogenase [NADP] icd 0.0066
3486 Fumarate hydratase class II fumC 0.0066
952 Dipeptidyl peptidase 4 DPP4 0.0064
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0064
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0062
857 Malate dehydrogenase, mitochondrial MDH2 0.0062
332 Beta-lactamase blaZ 0.0061
2478 Beta-lactamase ampC 0.0061
2613 Beta-lactamase ampC 0.0061
2635 Beta-lactamase ampC 0.0061
2700 Beta-lactamase penP 0.0061
5445 Beta-lactamase blaB 0.0061
6019 Beta-lactamase SHV-7 0.0061
6701 Beta-lactamase cphA 0.0061
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0061
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0061
2697 Uridine-cytidine kinase 2 UCK2 0.0061
1123 Eosinophil cationic protein RNASE3 0.0061
2452 Tryptophanyl-tRNA synthetase trpS 0.006
5579 Carboxypeptidase B CPB1 0.0058
3384 Macrophage migration inhibitory factor MIF 0.0057
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0056
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0056
411 Glycine N-methyltransferase GNMT 0.0054
128 Adenine phosphoribosyltransferase APRT 0.0049
5682 Ribonuclease pancreatic RNASE1 0.0044
822 Aldose reductase AKR1B1 0.0044
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0043
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0041
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0033
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