DT-Web

DB03759 - Dnqx


Identification
Name Dnqx
Accession Number DB03759 (EXPT01239)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 250.1247
Groups experimental
Monoisotopic Weight 249.997433816
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glutamate receptor 2
Name Glutamate receptor 2
Gene Name GRIA2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8054

Predictions


Id Partner name Gene Name Score
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0719
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0516
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0516
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0468
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0452
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0448
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0435
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0414
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0414
923 Glutamate receptor 3 GRIA3 0.0148
172 Potassium channel subfamily K member 1 KCNK1 0.0095
6016 Cytochrome P450 2C19 CYP2C19 0.0067
502 5-hydroxytryptamine 2A receptor HTR2A 0.0065
831 D(2) dopamine receptor DRD2 0.0064
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0059
4512 Cytochrome P450 3A4 CYP3A4 0.0055
4200 Cytochrome P450 1A2 CYP1A2 0.0047
4757 Cytochrome P450 2C9 CYP2C9 0.0046
6030 Cytochrome P450 2B6 CYP2B6 0.0042
6013 Cytochrome P450 2E1 CYP2E1 0.004
3937 Fatty-acid amide hydrolase FAAH 0.0038
4924 Cytochrome P450 2C8 CYP2C8 0.0037
5718 Cytochrome P450 2A6 CYP2A6 0.0032
20 Prostaglandin G/H synthase 1 PTGS1 0.0016
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0013
468 Cytochrome P450 4A11 CYP4A11 0.0012
6106 Cytochrome P450 2C18 CYP2C18 0.001
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.001
776 Bile salt export pump ABCB11 0.001
1898 Cytochrome P450 1B1 CYP1B1 0.001
922 Glutamate receptor 4 GRIA4 0.0009
862 Multidrug resistance-associated protein 1 ABCC1 0.0009
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0008
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0008
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0008
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0008
4027 Glutamate receptor delta-1 subunit GRID1 0.0008
4018 Glutamate receptor delta-2 subunit GRID2 0.0008
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0008
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0008
664 Glutamate decarboxylase 2 GAD2 0.0008
3890 Glutamate decarboxylase 2 GAD2 0.0008
4026 Aspartyl aminopeptidase DNPEP 0.0008
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0008
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0008
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0008
1912 Excitatory amino acid transporter 1 SLC1A3 0.0008
4016 Excitatory amino acid transporter 5 SLC1A7 0.0008
4019 Excitatory amino acid transporter 4 SLC1A6 0.0008
1047 Excitatory amino acid transporter 2 SLC1A2 0.0008
927 Metabotropic glutamate receptor 8 GRM8 0.0008
925 Metabotropic glutamate receptor 4 GRM4 0.0008
926 Metabotropic glutamate receptor 7 GRM7 0.0008
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0008
4020 Glutamyl aminopeptidase ENPEP 0.0008
4017 5-oxoprolinase OPLAH 0.0008
625 Glutamate carboxypeptidase 2 FOLH1 0.0008
6024 Cytochrome P450 1A1 CYP1A1 0.0008
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0008
6107 Cytochrome P450 3A7 CYP3A7 0.0007
5 Glutaminase liver isoform, mitochondrial GLS2 0.0007
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0007
917 Glutaminase kidney isoform, mitochondrial GLS 0.0007
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0007
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0007
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0007
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0007
5261 Phosphoribosylformylglycinamidine synthase purL 0.0007
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0007
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0007
665 Phosphoserine aminotransferase PSAT1 0.0007
4652 Phosphoserine aminotransferase serC 0.0007
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0007
420 Glutamate decarboxylase 1 GAD1 0.0007
3900 Glutamate decarboxylase 1 GAD1 0.0007
916 Metabotropic glutamate receptor 1 GRM1 0.0007
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0007
4118 Cytochrome P450 3A5 CYP3A5 0.0007
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0007
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0007
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0007
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0007
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0007
426 Aspartate aminotransferase, mitochondrial GOT2 0.0007
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0007
1671 Excitatory amino acid transporter 3 SLC1A1 0.0007
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0007
3877 Growth-inhibiting protein 18 GIG18 0.0007
1588 Multidrug resistance protein 1 ABCB1 0.0007
763 Tyrosine aminotransferase TAT 0.0006
5493 Tyrosine aminotransferase Not Available 0.0006
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0006
705 Glutamate receptor 1 GRIA1 0.0006
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0006
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0006
735 Alanine aminotransferase 1 GPT 0.0006
3904 Alanine aminotransferase 2 GPT2 0.0006
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0006
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0006
33 Cystine/glutamate transporter SLC7A11 0.0006
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0006
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0006
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0006
3426 Glutamine synthetase glnA 0.0006
3987 Glutamine synthetase GLUL 0.0006
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0006
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0006
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0005
738 Monocarboxylate transporter 1 SLC16A1 0.0005
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0005
6151 Monocarboxylate transporter 10 SLC16A10 0.0004
↑