DT-Web

DB03067 - 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid


Identification
Name 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid
Accession Number DB03067 (EXPT00062)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 586.4627
Groups experimental
Monoisotopic Weight 586.097207438
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glycogen phosphorylase, muscle form
Name Glycogen phosphorylase, muscle form
Gene Name PYGM
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6205

Predictions


Id Partner name Gene Name Score
10 Glycogen phosphorylase, liver form PYGL 0.0267
2503 Phosphomannomutase/phosphoglucomutase algC 0.0197
6614 Lactase-like protein LCTL 0.0185
6847 Lactase-phlorizin hydrolase LCT 0.015
3101 Glucose-1-phosphatase agp 0.0148
3091 Maltodextrin phosphorylase malP 0.0126
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0095
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0095
3799 Hypoxanthine phosphoribosyltransferase hpt 0.0092
3719 Inosine-5'-monophosphate dehydrogenase guaB 0.0092
2538 6-phospho-beta-glucosidase bglT bglT 0.0072
2393 Maltose-6'-phosphate glucosidase glvA 0.0072
1881 Hexokinase-1 HK1 0.0069
5492 Cystathionine gamma-synthase metB 0.0067
5491 Methionine gamma-lyase mdeA 0.0067
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0064
2439 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] otsA 0.0062
3950 Cell division protein kinase 9 CDK9 0.0062
3968 Cell division protein kinase 8 CDK8 0.0062
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0059
2632 Adenylosuccinate synthetase purA 0.0058
3323 Adenylosuccinate synthetase purA 0.0058
3975 Adenylosuccinate synthetase ADSS 0.0058
4598 Adenylosuccinate synthetase Adss 0.0058
6817 Adenylosuccinate synthetase purA 0.0058
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0057
2206 Glucose-6-phosphate isomerase GPI 0.0054
4823 L-allo-threonine aldolase TM_1744 0.0054
2758 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase bioA 0.0054
3482 Cell division protein kinase 7 CDK7 0.0054
3959 Cell division protein kinase 4 CDK4 0.0054
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0052
3955 Cell division protein kinase 6 CDK6 0.0049
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0048
449 Ornithine decarboxylase ODC1 0.0046
1742 D-HSCDK2 CDK2deltaT 0.0043
1771 Cell division control protein 2 homolog CDK1 0.0043
3321 Cell division control protein 2 homolog CRK2 0.0043
1058 Cell division protein kinase 5 CDK5 0.0042
2514 Phosphocarrier protein HPr ptsH 0.0041
5689 Phosphocarrier protein HPr ptsH 0.0041
3602 Anti-sigma F factor antagonist spoIIAA 0.0041
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0041
349 Serine--pyruvate aminotransferase AGXT 0.0041
822 Aldose reductase AKR1B1 0.0041
2249 Aspartate aminotransferase aspC 0.0039
2671 Aspartate aminotransferase aspC 0.0039
5490 Aspartate aminotransferase Not Available 0.0039
1130 Lithostathine 1 alpha REG1A 0.0036
4542 Glutaminase 1 glsA1 0.0036
4544 Glutaminase 1 glsA1 0.0036
4318 Siroheme synthase cysG 0.0033
3119 Fimbrial protein pilE1 0.0033
2530 Protein kinase C theta type PRKCQ 0.0033
844 Epidermal growth factor receptor EGFR 0.0033
3453 Alkaline phosphatase phoA 0.0031
5150 Endo-1,4-beta-xylanase Y xynY 0.003
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0024
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0023
2240 Cell division protein kinase 2 CDK2 0.0023
2207 Rhodopsin RHO 0.0023
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0022
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0019
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0018
3689 Endoglucanase A celA 0.0009
5563 Galectin-2 LGALS2 0.0009
5411 Slt-IIvB stxB2e 0.0009
5046 Ecotin eco 0.0009
5554 D-galactose-binding periplasmic protein mglB 0.0009
3741 D-galactose-binding periplasmic protein precursor mglB 0.0009
3009 Beta-glucanase Not Available 0.0009
1875 Pulmonary surfactant-associated protein D SFTPD 0.0009
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0009
5568 Endoglucanase C307 celC307 0.0009
5562 Hexokinase Not Available 0.0009
3744 Endoglucanase SS precursor celS 0.0009
3793 Aspartate ammonia-lyase aspA 0.0009
5569 Endo-1,4-beta glucanase EngF engF 0.0009
5553 Endoglucanase E1 Acel_0614 0.0009
5559 Neopullulanase nplT 0.0009
4670 Cellulase B celB 0.0009
4668 Laminarinase TM_0024 0.0009
4671 Endoglucanase C cenC 0.0009
5570 Endoglucanase E-4 celD 0.0009
4667 BH0236 protein BH0236 0.0009
1184 Interferon beta IFNB1 0.0008
4509 Acetoin(diacetyl) reductase budC 0.0008
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0008
5176 YtnJ moxC 0.0008
1503 Galectin-7 LGALS7 0.0008
5416 Coat protein VP1 Not Available 0.0008
5247 Endo-1,4-beta-xylanase Not Available 0.0008
5248 Endo-1,4-beta-xylanase xlnA 0.0008
5250 Endo-1,4-beta-xylanase xyl 0.0008
5498 Maltoporin lamB 0.0008
5561 Maltoporin lamB 0.0008
4622 Amylase Not Available 0.0008
2705 Dimethyl sulfoxide reductase dmsA 0.0008
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0008
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0008
4669 Endo-1,4-beta-xylanase A xynA 0.0008
4715 Endo-1,4-beta-xylanase A xlnA 0.0008
5560 Endo-1,4-beta-xylanase A xynA 0.0008
3875 Glycogen phosphorylase, brain form PYGB 0.0008
3882 Brain glycogen phosphorylase variant Not Available 0.0008
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0007
3547 Enterotoxin type B entB 0.0007
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0007
3747 Cellulase B precursor celB 0.0007
2531 Alpha-amylase amyE 0.0007
2948 Alpha-amylase amy 0.0007
3169 Alpha-amylase Not Available 0.0007
4819 Hydrolase Not Available 0.0007
5249 Hydrolase Not Available 0.0007
5436 Hydrolase Not Available 0.0007
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0007
2324 Botulinum neurotoxin type B botB 0.0007
2606 Neopullulanase 2 tvaII 0.0007
4811 Amylosucrase ams 0.0007
2541 Neopullulanase 1 tvaI 0.0007
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0007
3887 Phosphorylase PYGB 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
2826 Glucose--fructose oxidoreductase gfo 0.0007
2372 Bifunctional tail protein 9 0.0007
3225 Shiga toxin B-chain stxB 0.0007
4830 Aldose 1-epimerase galM 0.0007
3365 Beta-amylase spoII 0.0007
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.0007
3911 Uncharacterized protein C20orf38 SPTLC3 0.0007
3883 Ornithine aminotransferase variant Not Available 0.0007
306 Pyridoxal phosphate phosphatase PDXP 0.0007
3891 Putative L-Dopa decarboxylase DDC 0.0007
3881 Selenocysteine lyase variant Not Available 0.0007
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0007
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0007
3893 DDC protein DDC 0.0007
3880 Serine hydroxymethyltransferase 1 Not Available 0.0007
3906 Serine dehydratase-like SDSL 0.0007
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0007
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.0007
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0007
3886 Migration-inducing protein 4 ALAS1 0.0007
3878 GAD1 protein GAD1 0.0007
664 Glutamate decarboxylase 2 GAD2 0.0007
3890 Glutamate decarboxylase 2 GAD2 0.0007
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0007
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0007
3905 Molybdenum cofactor sulfurase MOCOS 0.0007
3894 KIAA0251 protein PDXDC1 0.0007
1675 Glucokinase GCK 0.0006
4662 Glucokinase glk 0.0006
3030 Salivary alpha-amylase AMY1A 0.0006
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0006
2508 Cyclomaltodextrin glucanotransferase cgt 0.0006
2523 Cyclomaltodextrin glucanotransferase cgt 0.0006
3207 Cyclomaltodextrin glucanotransferase amyA 0.0006
868 Cystathionine gamma-lyase CTH 0.0006
472 Ornithine aminotransferase, mitochondrial OAT 0.0006
3668 Maltose-binding periplasmic protein precursor malE 0.0006
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0006
2802 Endoglucanase G celCCG 0.0006
2570 Tetanus toxin tetX 0.0006
4692 A/G-specific adenine glycosylase mutY 0.0006
435 Kynureninase KYNU 0.0006
4654 Kynureninase kynU 0.0006
4272 POSSIBLE CELLULASE CELA1 celA1 0.0006
2440 Endoglucanase F celCCF 0.0006
2430 Chondroitinase B cslB 0.0006
3913 Glutamic acid decarboxylase GAD65 0.0006
184 L-serine dehydratase SDS 0.0006
431 Serine racemase SRR 0.0006
727 Serine palmitoyltransferase 2 SPTLC2 0.0006
491 Serine palmitoyltransferase 1 SPTLC1 0.0006
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0006
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0006
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0006
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0006
3 Histidine decarboxylase HDC 0.0006
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0006
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0006
665 Phosphoserine aminotransferase PSAT1 0.0006
4652 Phosphoserine aminotransferase serC 0.0006
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0006
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0006
420 Glutamate decarboxylase 1 GAD1 0.0006
3900 Glutamate decarboxylase 1 GAD1 0.0006
499 Arginine decarboxylase ADC 0.0006
534 Threonine synthase-like 1 THNSL1 0.0006
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0006
89 Cysteine sulfinic acid decarboxylase CSAD 0.0006
426 Aspartate aminotransferase, mitochondrial GOT2 0.0006
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0006
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0006
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0006
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0005
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0005
2245 Xylose isomerase xylA 0.0005
2253 Xylose isomerase xylA 0.0005
2260 Xylose isomerase xylA 0.0005
2431 Xylose isomerase xylA 0.0005
2252 Endoglucanase 5A cel5A 0.0005
2723 Cholera enterotoxin subunit B ctxB 0.0005
358 Cystathionine beta-synthase CBS 0.0005
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0005
3884 SHMT2 protein SHMT2 0.0005
3901 SHMT2 protein SHMT2 0.0005
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0005
3879 Serine hydroxymethyltransferase 2 Not Available 0.0005
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0005
3877 Growth-inhibiting protein 18 GIG18 0.0005
169 Cysteine desulfurase, mitochondrial NFS1 0.0005
2427 Ferrichrome-iron receptor fhuA 0.0005
4513 Pancreatic alpha-amylase AMY2A 0.0005
763 Tyrosine aminotransferase TAT 0.0005
5493 Tyrosine aminotransferase Not Available 0.0005
3904 Alanine aminotransferase 2 GPT2 0.0005
735 Alanine aminotransferase 1 GPT 0.0005
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0005
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0005
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0005
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0005
20 Prostaglandin G/H synthase 1 PTGS1 0.0003
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