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Lantibiotic mersacidin


Partner ID 4551
Name Lantibiotic mersacidin
Synonyms 6947
Gene name mrsA
General function Not Available
Specific function Kills a number of Gram-positive bacteria. Acts at the level of cell wall biosynthesis by interfering with bacterial peptidoglycan biosynthesis. Specifically inhibits the conversion of the lipid II intermediate into polymeric nascent glycan strands by transglycosylation. May interact with the peptidoglycan precursor rather than with the enzyme
Gene sequence + ...

ATGAGTCAAGAAGCTATCATTCGTTCATGGAAAGATCCTTTTTCCCGTGAAAATTCTACACAAAATCCAGCTGGTAACCCATTCAGTGAGCTGAAAGAAGCACAAATGGATAAGTTAGTAGGTGCGGGAGACATGGAAGCAGCATGTACTTTTACATTGCCTGGTGGCGGCGGTGTTTGTACTCTAACTTCTGAATGTATTTGTTAA
Protein sequence + ...

MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDMEAACTFTLPGGGGVCTLTSECIC
GO Classification Not Available
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Drugs


Associated as Target

Id Name
DB01968 2-Thioethenamine
DB02688 2,3-Didehydroalanine
DB04454 Alpha-Aminobutyric Acid

Associated as Prediction

Id Name
DB00129 L-Ornithine
DB00145 Glycine
DB00364 Sucralfate
DB01968 2-Thioethenamine
DB02068 Delta-Amino Valeric Acid
DB02411 2-(11-{2-[Benzenesulfonyl-(3-Methyl-Butyl)-Amino]-1-Hydroxy-Ethyl}-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-8-Yl)-Acetamide, Inhibitor 2
DB02530 Gamma(Amino)-Butyric Acid
DB02668 Je-2147, Ag1776, Kni-764
DB02688 2,3-Didehydroalanine
DB03149 Phenylalanylmethane
DB03768 N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3
DB04185 Norvaline
DB04454 Alpha-Aminobutyric Acid
DB07679 (9S,12S)-9-(1-methylethyl)-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid
DB07910 PHENYLALANINDIOL
DB08622 4-(4-CHLORO-PHENYL)-1-{3-[2-(4-FLUORO-PHENYL)-[1,3]DITHIOLAN-2-YL]-PROPYL}-PIPERIDIN-4-OL
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